DK619989A - Dipeptidderivater, deres fremstilling og anvendelse som laegemidler - Google Patents

Dipeptidderivater, deres fremstilling og anvendelse som laegemidler Download PDF

Info

Publication number: DK619989A
Authority: DK; Denmark
Prior art keywords: pharmaceuticals; preparation; dipeptide derivatives; dipeptide; derivatives
Prior art date: 1988-12-10

Application number

DK619989A

Other languages

English (en)

Other versions

DK619989D0 (da

Inventor

Wolf-Ulrich Nickel

Hansjoerg Urbach

Dieter Ruppert

Bernward Schoelkens

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-12-10

Filing date

1989-12-08

Publication date

1990-06-11

1989-12-08 Application filed by Hoechst Ag filed Critical Hoechst Ag

1989-12-08 Publication of DK619989D0 publication Critical patent/DK619989D0/da

1990-06-11 Publication of DK619989A publication Critical patent/DK619989A/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cardiology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Engineering & Computer Science (AREA)
Virology (AREA)
Bioinformatics & Cheminformatics (AREA)
Heart & Thoracic Surgery (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DK619989A 1988-12-10 1989-12-08 Dipeptidderivater, deres fremstilling og anvendelse som laegemidler DK619989A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE3841732A DE3841732A1 (de)	1988-12-10	1988-12-10	Dipeptid-derivate mit enzym-inhibitorischer wirkung

Publications (2)

Publication Number	Publication Date
DK619989D0 DK619989D0 (da)	1989-12-08
DK619989A true DK619989A (da)	1990-06-11

Family

ID=6368937

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK619989A DK619989A (da)	1988-12-10	1989-12-08	Dipeptidderivater, deres fremstilling og anvendelse som laegemidler

Country Status (15)

Country	Link
EP (1)	EP0373497A3 (da)
JP (1)	JPH02202899A (da)
KR (1)	KR900009687A (da)
CN (1)	CN1043132A (da)
AU (1)	AU634188B2 (da)
DD (1)	DD290895A5 (da)
DE (1)	DE3841732A1 (da)
DK (1)	DK619989A (da)
FI (1)	FI895874A7 (da)
HU (1)	HU206371B (da)
IL (1)	IL92618A0 (da)
NO (1)	NO894944L (da)
PT (1)	PT92496A (da)
RU (1)	RU1836381C (da)
ZA (1)	ZA899407B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0546115A1 (en) *	1990-08-24	1993-06-16	The Upjohn Company	Peptides containing amino-polyols as transition-state mimics
US6313094B1 (en)	1990-12-11	2001-11-06	Japan Energy Corporation	β-amino-α-hydroxycarboxylic acid derivatives and HIV protease inhibitors
PL294866A1 (en) *	1991-06-21	1993-05-31	Hoechst Ag	Method of obtaining novel rennin redtarding heterocyclic compounds
PL294870A1 (da) *	1991-06-21	1993-02-08	Hoechst Ag
EP1155009A2 (en) *	1999-02-19	2001-11-21	Oklahoma Medical Research Foundation	Protease inhibitors that overcome drug resistance
US6969731B1 (en)	1999-02-19	2005-11-29	The University of Illinois, Board of Trustees	Protease inhibitors that overcome drug resistance
DE10029077A1 (de) *	2000-06-13	2001-12-20	Bayer Ag	Thiazolylsubstituierte Heterocyclen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3627877A1 (de) *	1986-07-30	1988-02-04	Hoechst Ag	Renin-hemmende di- und tripeptide, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung
SE8605573D0 (sv) *	1986-12-29	1986-12-29	Haessle Ab	Novel compounds

1988
- 1988-12-10 DE DE3841732A patent/DE3841732A1/de not_active Withdrawn
1989
- 1989-12-06 PT PT92496A patent/PT92496A/pt not_active Application Discontinuation
- 1989-12-06 EP EP19890122519 patent/EP0373497A3/de not_active Withdrawn
- 1989-12-07 DD DD89335367A patent/DD290895A5/de not_active IP Right Cessation
- 1989-12-08 JP JP1317941A patent/JPH02202899A/ja active Pending
- 1989-12-08 DK DK619989A patent/DK619989A/da not_active Application Discontinuation
- 1989-12-08 KR KR1019890018152A patent/KR900009687A/ko not_active Withdrawn
- 1989-12-08 ZA ZA899407A patent/ZA899407B/xx unknown
- 1989-12-08 AU AU46003/89A patent/AU634188B2/en not_active Ceased
- 1989-12-08 RU SU894742564A patent/RU1836381C/ru active
- 1989-12-08 NO NO89894944A patent/NO894944L/no unknown
- 1989-12-08 HU HU896475A patent/HU206371B/hu not_active IP Right Cessation
- 1989-12-08 IL IL92618A patent/IL92618A0/xx unknown
- 1989-12-08 FI FI895874A patent/FI895874A7/fi not_active Application Discontinuation
- 1989-12-09 CN CN89109164A patent/CN1043132A/zh active Pending

Also Published As

Publication number	Publication date
HU896475D0 (en)	1990-02-28
HU206371B (en)	1992-10-28
KR900009687A (ko)	1990-07-05
RU1836381C (ru)	1993-08-23
IL92618A0 (en)	1990-08-31
ZA899407B (en)	1990-08-29
DE3841732A1 (de)	1990-06-13
DK619989D0 (da)	1989-12-08
NO894944D0 (no)	1989-12-08
HUT54176A (en)	1991-01-28
FI895874A7 (fi)	1990-06-11
DD290895A5 (de)	1991-06-13
FI895874A0 (fi)	1989-12-08
JPH02202899A (ja)	1990-08-10
PT92496A (pt)	1990-06-29
CN1043132A (zh)	1990-06-20
AU634188B2 (en)	1993-02-18
NO894944L (no)	1990-06-11
AU4600389A (en)	1990-08-09
EP0373497A3 (de)	1991-04-10
EP0373497A2 (de)	1990-06-20

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Legal Events

Date	Code	Title	Description
1993-09-27	ATS	Application withdrawn