DK633789A - Benzothiazol-derivater, deres fremstilling og anvendelse i laegemidler - Google Patents

Benzothiazol-derivater, deres fremstilling og anvendelse i laegemidler Download PDF

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Publication number
DK633789A
DK633789A DK633789A DK633789A DK633789A DK 633789 A DK633789 A DK 633789A DK 633789 A DK633789 A DK 633789A DK 633789 A DK633789 A DK 633789A DK 633789 A DK633789 A DK 633789A
Authority
DK
Denmark
Prior art keywords
pharmaceuticals
preparation
benzothiazol
derivatives
benzothiazol derivatives
Prior art date
Application number
DK633789A
Other languages
English (en)
Other versions
DK633789D0 (da
DK169921B1 (da
Inventor
Francois Audiau
Claude Gueremy
Patrick Jimonet
Serge Mignani
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8816547A external-priority patent/FR2640623B1/fr
Priority claimed from FR8909482A external-priority patent/FR2649703B1/fr
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of DK633789D0 publication Critical patent/DK633789D0/da
Publication of DK633789A publication Critical patent/DK633789A/da
Application granted granted Critical
Publication of DK169921B1 publication Critical patent/DK169921B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK633789A 1988-12-15 1989-12-14 2-Iminobenzothiazolin-forbindelser, fremgangsmåder til deres fremstilling, lægemidler med indhold deraf og deres anvendelse til fremstilling af lægemidler. DK169921B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8816547 1988-12-15
FR8816547A FR2640623B1 (fr) 1988-12-15 1988-12-15 Derives de la benzothiazoline, leurs procedes de preparation et les medicaments les contenant
FR8909482A FR2649703B1 (fr) 1989-07-13 1989-07-13 Derives d'imino-2 polyfluoroalcoxy-6 benzothiazole, leurs procedes de preparation et les medicaments les contenant
FR8909482 1989-07-13

Publications (3)

Publication Number Publication Date
DK633789D0 DK633789D0 (da) 1989-12-14
DK633789A true DK633789A (da) 1990-06-16
DK169921B1 DK169921B1 (da) 1995-04-03

Family

ID=26227050

Family Applications (1)

Application Number Title Priority Date Filing Date
DK633789A DK169921B1 (da) 1988-12-15 1989-12-14 2-Iminobenzothiazolin-forbindelser, fremgangsmåder til deres fremstilling, lægemidler med indhold deraf og deres anvendelse til fremstilling af lægemidler.

Country Status (12)

Country Link
US (2) US4980356A (da)
EP (1) EP0375510B1 (da)
JP (1) JPH0733377B2 (da)
CA (1) CA2005591A1 (da)
DE (1) DE68903484T2 (da)
DK (1) DK169921B1 (da)
ES (1) ES2052954T3 (da)
FI (1) FI93107C (da)
GR (1) GR3006372T3 (da)
IE (1) IE62406B1 (da)
NO (1) NO174200C (da)
PT (1) PT92605B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260297A (en) * 1989-07-13 1993-11-09 Rhone Poulenc Rorer, S.A. 2-imino-3-alkylbenzothiazoline derivatives bearing a heterocyclic substituent on the alkyl group, their preparation and medicinal products containing them.
ES2062445T3 (es) * 1989-07-13 1994-12-16 Rhone Poulenc Sante Derivados de imino-2 heterociclilalquil-3 benzotiazolina, su preparacion y los medicamentos que les contienen.
US5240948A (en) * 1989-12-13 1993-08-31 Rhone-Poulenc Rorer Pharmaceuticals Inc. 3-(3-alkylthiopropyl)benzothiazoline derivatives, their preparation and the medicament containing them
FR2663029B1 (fr) * 1990-06-07 1992-07-31 Rhone Poulenc Sante Derives de benzothiazole, leur preparation et les medicaments les contenant.
FR2678619B1 (fr) * 1991-07-04 1993-09-17 Rhone Poulenc Rorer Sa Derives de 1,2,4-thiadiazolo[3,4-b]benzothiazole, leur preparation et les medicaments les contenant.
FR2688138B1 (fr) * 1992-03-06 1995-05-05 Rhone Poulenc Rorer Sa Application de l'amino-2 trifluoromethoxy-6 benzothiazole pour obtenir un medicament destine au traitement de la sclerose laterale amyotrophique.
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
WO1998013046A1 (en) 1996-09-27 1998-04-02 Guilford Pharmaceuticals Inc. Naaladase compositions and methods for treating glutamate abnormality and effecting neuronal activity in animals
DE10232440B4 (de) 2002-06-28 2018-06-07 Zf Friedrichshafen Ag Antriebssystem für ein Fahrzeug
CN111689929B (zh) 2014-06-06 2024-05-31 斯克里普斯研究所 氟化硫(vi)化合物及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2631163B2 (de) * 1976-07-10 1978-06-29 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 2-Iminobenzothiazolen
FR2492258A1 (fr) * 1980-10-17 1982-04-23 Pharmindustrie Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole
US4826860A (en) * 1987-03-16 1989-05-02 Warner-Lambert Company Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents
FI91859C (fi) * 1987-06-17 1994-08-25 Eisai Co Ltd Analogiamenetelmä antiallergisena aineena aktiivisen bentsotiatsolijohdannaisen valmistamiseksi

Also Published As

Publication number Publication date
PT92605A (pt) 1990-06-29
PT92605B (pt) 1995-09-12
IE62406B1 (en) 1995-01-25
EP0375510A1 (fr) 1990-06-27
CA2005591A1 (fr) 1990-06-15
JPH02223570A (ja) 1990-09-05
FI93107B (fi) 1994-11-15
NO174200B (no) 1993-12-20
GR3006372T3 (da) 1993-06-21
IE894007L (en) 1990-06-15
ES2052954T3 (es) 1994-07-16
FI93107C (fi) 1995-02-27
NO895031L (no) 1990-06-18
EP0375510B1 (fr) 1992-11-11
DK633789D0 (da) 1989-12-14
US4980356A (en) 1990-12-25
NO174200C (no) 1994-04-06
JPH0733377B2 (ja) 1995-04-12
NO895031D0 (no) 1989-12-14
US5026717A (en) 1991-06-25
DE68903484D1 (de) 1992-12-17
DK169921B1 (da) 1995-04-03
DE68903484T2 (de) 1993-03-18
FI895982A0 (fi) 1989-12-14

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed