DK628087A - Diazepinderivater - Google Patents

Diazepinderivater

Info

Publication number: DK628087A
Authority: DK; Denmark
Prior art keywords: diazepine
Prior art date: 1986-12-15

Application number

DK628087A

Other languages

English (en)

Other versions

DK628087D0 (da

Inventor

Geoffrey Lawton

Sally Redshaw

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-12-15

Filing date

1987-11-30

Publication date

1988-06-16

1987-11-30 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1987-11-30 Publication of DK628087D0 publication Critical patent/DK628087D0/da

1988-06-16 Publication of DK628087A publication Critical patent/DK628087A/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Pharmacology & Pharmacy (AREA)
Cardiology (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK628087A 1986-12-15 1987-11-30 Diazepinderivater DK628087A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB868629875A GB8629875D0 (en)	1986-12-15	1986-12-15	Pyridazodiazepine derivatives

Publications (2)

Publication Number	Publication Date
DK628087D0 DK628087D0 (da)	1987-11-30
DK628087A true DK628087A (da)	1988-06-16

Family

ID=10609005

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK628087A DK628087A (da)	1986-12-15	1987-11-30	Diazepinderivater

Country Status (17)

Country	Link
US (2)	US4757069A (da)
EP (1)	EP0271795A3 (da)
JP (1)	JPS63162693A (da)
KR (1)	KR880007538A (da)
AU (1)	AU602546B2 (da)
CA (1)	CA1291478C (da)
DK (1)	DK628087A (da)
FI (1)	FI85482C (da)
GB (1)	GB8629875D0 (da)
HU (1)	HU198492B (da)
IL (1)	IL84765A (da)
MC (1)	MC1879A1 (da)
NO (1)	NO166083C (da)
NZ (1)	NZ222825A (da)
PH (1)	PH23813A (da)
PT (1)	PT86365B (da)
ZA (1)	ZA879229B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5430145A (en) *	1990-10-18	1995-07-04	Merrell Dow Pharmaceuticals Inc.	Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace
US5308841A (en) *	1990-12-21	1994-05-03	Merrell Dow Pharmaceuticals Inc.	Amino and nitro containing tricyclic compounds useful as inhibitors of ACE
DE69220744T2 (de) *	1991-09-27	1997-11-13	Merrell Pharma Inc	2-Substituierte Indan-2-Mercaptoacetylamid-Verbindungen mit Enkephalinase und ACE-Hemmwirkung
US5457196A (en) *	1991-09-27	1995-10-10	Merrell Dow Pharmaceuticals Inc.	2-substituted indane-2-carboxyalkyl derivatives useful as inhibitors of enkephalinase and ACE
US5455242A (en) *	1991-09-27	1995-10-03	Merrell Dow Pharmaceuticals Inc.	Carboxyalkyl tricyclic derivatives useful as inhibitors of enkephalinase and ace
AU668707B2 (en) *	1992-02-14	1996-05-16	Merrell Pharmaceuticals Inc.	Aminoacetylmercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ACE
DK0640086T3 (da) *	1992-05-15	1999-12-06	Merrell Pharma Inc	Mercaptoacetylamido-pyridazo[1,2-a][1,2]diazepin-derivateranvendelige som enkephalinase- og ACE-inhibitorer
US5420271A (en) *	1992-08-24	1995-05-30	Merrell Dow Pharmaceuticals, Inc.	2-substituted indane-2-mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase
DE69329701T2 (de) *	1992-10-30	2001-05-10	Merrell Pharmaceuticals Inc., Cincinnati	Mercaptoacetylamid substituiertes bizyclisches laktam zur verwendung als enkephalinase und ace-hemmer
DE69516128T2 (de) *	1994-02-14	2000-12-21	Merrell Pharmaceuticals Inc., Cincinnati	Mercaptoacetylamid-1,3,4,5-tetrahydrobenzo(c)azepin-3-ein disulfidderivate als enkephalinase und ace inhibitoren
CN1142831A (zh) *	1994-02-14	1997-02-12	默里尔药物公司	用作脑啡肽酶和ace抑制剂的新的2-取代的1，2-二氢化茚-2-巯基乙酰胺二硫化物衍生物
HUT74584A (en) *	1994-02-14	1997-01-28	Merrell Pharma Inc	Novel heterocycle fused benzazepine-2-mercaptoacetylamide disulfide derivatives useful as inhibitors of enkephalinase, process for producing them and pharmaceutical compositions containing them
ATE177098T1 (de) *	1994-02-14	1999-03-15	Merrell Pharma Inc	Mercaptoacetylamid disulfidderivate als enkephalinase und ace inhibitoren
US5530013A (en) *	1994-02-14	1996-06-25	American Home Products Corporation	Venlafaxine in the inducement of cognition enhancement
US5484783A (en) *	1994-03-24	1996-01-16	Merrell Dow Pharmaceuticals Inc.	Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide and benzazapine derivatives
FI963784A0 (fi) *	1994-03-24	1996-09-23	Merrell Pharma Inc	Hypokolesteroleemisiä, antiateroskleroottisia ja hypotriglyserideemisiä merkaptoasetyyliamididisulfidijohdannaisia
ATE189392T1 (de) *	1994-03-24	2000-02-15	Merrell Pharma Inc	Hypocholesterolemische, antiatherosklerotische und hypotriglyceridemische verwendung von aminoacetylmercapto derivaten
AU2000265534A1 (en) *	2000-02-17	2001-08-27	China Petroleum And Chemical Corporation	Multiblock copolymer the preparing method thereof
GB0119305D0 (en)	2001-04-12	2001-10-03	Aventis Pharma Gmbh	Mercaptoacetylamide derivatives,a process for their preparation and their use
IE20070935A1 (en) *	2007-12-21	2009-06-24	Trinity College Dublin	Guanidine based compounds and their use in the treatment of mental and neurological disorders.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4092438A (en) *	1977-04-29	1978-05-30	Carnation Company	Non-dairy coffee whitener containing acetate salt
GB2128984B (en) *	1982-05-12	1985-05-22	Hoffmann La Roche	Diaza-bicyclic compounds
GB8320764D0 (en) *	1983-08-02	1983-09-01	Rhodes Joseph Ltd	Bending machines
US4692438A (en) *	1984-08-24	1987-09-08	Hoffmann-La Roche Inc.	Pyridazo-diazepines, diazocines, and -triazepines having anti-hypertensive activity
EP0187037A3 (en) *	1984-12-21	1988-03-23	Takeda Chemical Industries, Ltd.	Piperidine derivatives, their production and use

1986
- 1986-12-15 GB GB868629875A patent/GB8629875D0/en active Pending
1987
- 1987-11-24 US US07/124,749 patent/US4757069A/en not_active Expired - Fee Related
- 1987-11-30 DK DK628087A patent/DK628087A/da not_active Application Discontinuation
- 1987-12-07 NZ NZ222825A patent/NZ222825A/en unknown
- 1987-12-07 EP EP87118047A patent/EP0271795A3/de not_active Ceased
- 1987-12-08 ZA ZA879229A patent/ZA879229B/xx unknown
- 1987-12-08 CA CA000553720A patent/CA1291478C/en not_active Expired - Lifetime
- 1987-12-09 IL IL84765A patent/IL84765A/xx unknown
- 1987-12-09 AU AU82254/87A patent/AU602546B2/en not_active Ceased
- 1987-12-10 MC MC871934A patent/MC1879A1/fr unknown
- 1987-12-11 HU HU875592A patent/HU198492B/hu unknown
- 1987-12-14 PH PH36217A patent/PH23813A/en unknown
- 1987-12-14 JP JP62314308A patent/JPS63162693A/ja active Pending
- 1987-12-14 FI FI875483A patent/FI85482C/fi not_active IP Right Cessation
- 1987-12-14 NO NO875200A patent/NO166083C/no unknown
- 1987-12-14 KR KR870014258A patent/KR880007538A/ko not_active Withdrawn
- 1987-12-15 PT PT86365A patent/PT86365B/pt not_active IP Right Cessation
1988
- 1988-03-17 US US07/169,266 patent/US4782149A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
MC1879A1 (fr)	1989-01-24
ZA879229B (en)	1988-06-15
JPS63162693A (ja)	1988-07-06
EP0271795A3 (de)	1989-08-09
PT86365B (pt)	1990-11-20
PH23813A (en)	1989-11-23
NO875200D0 (no)	1987-12-14
HUT47279A (en)	1989-02-28
FI85482B (fi)	1992-01-15
PT86365A (en)	1988-01-01
NZ222825A (en)	1990-11-27
GB8629875D0 (en)	1987-01-28
NO166083C (no)	1991-05-29
FI85482C (fi)	1992-04-27
EP0271795A2 (de)	1988-06-22
FI875483A0 (fi)	1987-12-14
KR880007538A (ko)	1988-08-27
IL84765A (en)	1991-06-30
DK628087D0 (da)	1987-11-30
HU198492B (en)	1989-10-30
NO166083B (no)	1991-02-18
US4757069A (en)	1988-07-12
FI875483L (fi)	1988-06-16
NO875200L (no)	1988-06-16
CA1291478C (en)	1991-10-29
US4782149A (en)	1988-11-01
AU602546B2 (en)	1990-10-18
IL84765A0 (en)	1988-05-31
AU8225487A (en)	1988-06-16

Legal Events

Date	Code	Title	Description
1994-07-25	AHB	Application shelved due to non-payment

Publication	Publication Date	Title
AT399804B (de)	1995-07-25	Sportschuh
DK126388D0 (da)	1988-03-09	Referenceelektrode
DK628087D0 (da)	1987-11-30	Diazepinderivater
DK190789D0 (da)	1989-04-19	Diazepinderivater
AT386436B (de)	1988-08-25	Schachtsystem
ATA48386A (de)	1988-08-15	Kranbahn
BR8603659A (pt)	1988-02-09	Mini-infiltrometro
ATA179487A (de)	1990-12-15	Maishaecksler
BR8603768A (pt)	1988-05-17	Perspectivografo
BR8604278A (pt)	1987-08-04	Oxigenador
BR8600774A (pt)	1987-09-08	Popette
BR6600378U (pt)	1987-11-03	Agenda-calendario
BR6600467U (pt)	1987-11-10	Antiassalt
SE8602709D0 (sv)	1986-06-18	Vermevexlare
SE8600732D0 (sv)	1986-02-19	Fodervineger
BR8604705A (pt)	1988-05-10	Vibro-massageador
BR6600495U (pt)	1987-11-10	Micro-fragmentadora
BR6600559U (pt)	1987-12-01	Mini-tripe
BR8604578A (pt)	1988-05-10	Endovaporizadora
BR6600239U (pt)	1987-10-13	Condutivimetro
BR8604238A (pt)	1988-04-26	Minibol
BR8604019A (pt)	1988-04-19	Doc-junior dossie infanto-juvenil
BR6600215U (pt)	1987-10-06	Duplo-ventilador
BR6600893U (pt)	1987-09-29	Aiveca
BR8601218A (pt)	1987-10-27	Lencol casulo