DK67582A - Fremgangsmaade til fremstilling af aroylimidazol-2-oner - Google Patents

Fremgangsmaade til fremstilling af aroylimidazol-2-oner Download PDF

Info

Publication number: DK67582A
Authority: DK; Denmark
Prior art keywords: alkyl; aroylimidazole; oner; preparing; procedure
Prior art date: 1981-02-18

Application number

DK67582A

Other languages

English (en)

Other versions

DK161250C (da

DK161250B (da

Inventor

R A Schnettler

R C Dage

J M Grisar

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-02-18

Filing date

1982-02-16

Publication date

1982-08-19

1982-02-16 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1982-08-19 Publication of DK67582A publication Critical patent/DK67582A/da

1991-06-17 Publication of DK161250B publication Critical patent/DK161250B/da

1991-12-09 Application granted granted Critical

1991-12-09 Publication of DK161250C publication Critical patent/DK161250C/da

Links

125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
-1 methylenedioxy Chemical group 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 1
125000002941 2-furyl group Chemical group O1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
125000005360 alkyl sulfoxide group Chemical group 0.000 abstract 1
125000004414 alkyl thio group Chemical group 0.000 abstract 1
230000002785 anti-thrombosis Effects 0.000 abstract 1
239000002220 antihypertensive agent Substances 0.000 abstract 1
229940030600 antihypertensive agent Drugs 0.000 abstract 1
229960004676 antithrombotic agent Drugs 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
239000000496 cardiotonic agent Substances 0.000 abstract 1
230000003177 cardiotonic effect Effects 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical group 0.000 abstract 1
150000002431 hydrogen Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Cardiology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Hematology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Diaphragms For Electromechanical Transducers (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Polyurethanes Or Polyureas (AREA)
Luminescent Compositions (AREA)
Cephalosporin Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DK067582A 1981-02-18 1982-02-16 Analogifremgangsmaade til fremstilling af 4-aroyl-imidazol-2-oner eller pharmaceutisk acceptable salte deraf DK161250C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US23545381A	1981-02-18	1981-02-18
US23545381		1981-02-18

Publications (3)

Publication Number	Publication Date
DK67582A true DK67582A (da)	1982-08-19
DK161250B DK161250B (da)	1991-06-17
DK161250C DK161250C (da)	1991-12-09

Family

ID=22885573

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK067582A DK161250C (da)	1981-02-18	1982-02-16	Analogifremgangsmaade til fremstilling af 4-aroyl-imidazol-2-oner eller pharmaceutisk acceptable salte deraf

Country Status (18)

Country	Link
EP (1)	EP0058435B1 (da)
JP (1)	JPS57150668A (da)
KR (1)	KR860001338B1 (da)
AT (1)	ATE24496T1 (da)
AU (1)	AU558789B2 (da)
CA (1)	CA1173047A (da)
DE (1)	DE3274855D1 (da)
DK (1)	DK161250C (da)
ES (1)	ES509636A0 (da)
GB (1)	GB2093031B (da)
GR (1)	GR76025B (da)
HK (1)	HK61586A (da)
IE (1)	IE52422B1 (da)
IL (1)	IL65010A0 (da)
MY (1)	MY8600710A (da)
NZ (1)	NZ199733A (da)
PH (1)	PH18106A (da)
ZA (1)	ZA82969B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4405628A (en) *	1981-03-05	1983-09-20	Merrell Dow Pharmaceuticals Inc.	4-Pyridylimidazolones and method of use
US4410540A (en) *	1981-11-04	1983-10-18	Merrell Dow Pharmaceuticals Inc.	Cardiotonic 4-aroylimidazolidin-2-ones
US4367236A (en) *	1981-11-04	1983-01-04	Merrell Dow Pharmaceuticals Inc.	Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
ZA826501B (en) *	1982-09-06	1984-04-25	Du Pont	Anti-hypertensive imidazole derivative
US4552880A (en) *	1983-02-15	1985-11-12	Merrell Dow Pharmaceuticals Inc.	Aroylimidazolones
US4556665A (en) *	1984-07-09	1985-12-03	Schering A.G.	Cardiotonic 1,3-dihydro-4-[[(imidazol-1-yl)aryl]carbonyl]imidazol-2-ones
EP1737448A1 (en) *	2004-03-22	2007-01-03	Myogen, Inc.	(s) - enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
JP2007530566A (ja) *	2004-03-22	2007-11-01	ミオゲンインコーポレイティッド	（ｒ）−エノキシモンスルホキシドおよびｐｄｅ−ｉｉｉ媒介疾患の治療におけるその使用
CN117105827A (zh) *	2017-03-27	2023-11-24	魁北克电力公司	用于电解质组合物中或用作电极添加剂的盐

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA803332B (en) *	1979-06-18	1981-01-28	Richardson Merrell Inc	Novel 4-aroylimidazol-2-ones
NZ193935A (en) *	1979-06-18	1985-05-31	Richardson Merrell Inc	4-aroyl-imidazol-2-one derivatives;pharmaceutical compositions

1982
- 1982-02-12 PH PH26861A patent/PH18106A/en unknown
- 1982-02-14 IL IL65010A patent/IL65010A0/xx unknown
- 1982-02-15 NZ NZ199733A patent/NZ199733A/en unknown
- 1982-02-15 AU AU80486/82A patent/AU558789B2/en not_active Expired
- 1982-02-15 CA CA000396247A patent/CA1173047A/en not_active Expired
- 1982-02-15 ZA ZA82969A patent/ZA82969B/xx unknown
- 1982-02-15 GR GR67318A patent/GR76025B/el unknown
- 1982-02-16 IE IE333/82A patent/IE52422B1/en not_active IP Right Cessation
- 1982-02-16 DK DK067582A patent/DK161250C/da not_active IP Right Cessation
- 1982-02-16 ES ES509636A patent/ES509636A0/es active Granted
- 1982-02-16 JP JP57022154A patent/JPS57150668A/ja active Granted
- 1982-02-17 GB GB8204721A patent/GB2093031B/en not_active Expired
- 1982-02-18 EP EP82101233A patent/EP0058435B1/en not_active Expired
- 1982-02-18 AT AT82101233T patent/ATE24496T1/de not_active IP Right Cessation
- 1982-02-18 DE DE8282101233T patent/DE3274855D1/de not_active Expired
- 1982-02-18 KR KR8200715A patent/KR860001338B1/ko not_active Expired
1986
- 1986-08-21 HK HK615/86A patent/HK61586A/xx not_active IP Right Cessation
- 1986-12-30 MY MY710/86A patent/MY8600710A/xx unknown

Also Published As

Publication number	Publication date
PH18106A (en)	1985-03-21
DK161250C (da)	1991-12-09
AU8048682A (en)	1982-08-26
CA1173047A (en)	1984-08-21
KR830009045A (ko)	1983-12-17
JPS57150668A (en)	1982-09-17
ES8307002A1 (es)	1983-07-01
IE820333L (en)	1982-08-18
ES509636A0 (es)	1983-07-01
KR860001338B1 (ko)	1986-09-15
HK61586A (en)	1986-08-29
IL65010A0 (en)	1982-04-30
GR76025B (da)	1984-08-03
EP0058435A2 (en)	1982-08-25
EP0058435A3 (en)	1984-03-21
NZ199733A (en)	1985-05-31
ATE24496T1 (de)	1987-01-15
DK161250B (da)	1991-06-17
DE3274855D1 (de)	1987-02-05
GB2093031B (en)	1984-10-24
IE52422B1 (en)	1987-10-28
ZA82969B (en)	1983-09-28
AU558789B2 (en)	1987-02-12
JPH048421B2 (da)	1992-02-17
EP0058435B1 (en)	1986-12-30
MY8600710A (en)	1986-12-31
GB2093031A (en)	1982-08-25

Legal Events

Date	Code	Title	Description
2002-03-04	PUP	Patent expired

Publication	Publication Date	Title
DK1026147T3 (da)	2004-03-22	Forbindelser, der er anvendelige som mellemprodukter i fremstillingen af piperidinderivater
DK0795025T3 (da)	2003-08-04	Enantioselektiv fremstilling af farmaceutisk aktive sulfoxider ved bioreduktion
FI970246A7 (fi)	1997-01-21	Dihydrobentsofuraanit
AU558789B2 (en)	1987-02-12	4-aroylimidazol-2-ones
DE3575140D1 (de)	1990-02-08	Dreizyklische oxindole als antientzuendungsmittel.
MA21995A1 (fr)	1991-07-01	Nouvelles fluoronaphthacenediones,leurs derives glycozyles et leurs procedes de fabrication .
FR2694020B1 (fr)	1994-10-14	Procédé de préparation de substances aromatiques par voie enzymatique.
AU552310B2 (en)	1986-05-29	4-aroylimidazolin-2-ones
DK0573464T3 (da)	1997-09-01	Fremgangsmåde til fremstilling af trans-piperidin-2,5-dicarboxylater
DK552682A (da)	1983-06-15	Fremgangsmaade til fremstilling af hydroxybenzylaminobenzener
BG102488A (en)	1999-04-30	Pesticidal compounds, compositions and methods for their preparation
DK0543584T3 (da)	1996-07-01	Benzo(b)thiophen-2-carboxamider til behandling af forstyrrelser i centralnervesystemet
DE3781783D1 (de)	1992-10-22	N-alkyl-derivate von 2-amino-6,7-dimethoxytetralin, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen mit antihypertensiver wirkung.
DK537180A (da)	1981-06-22	Fremgangsmaade til fremstilling af 4-amino-2,6-diaryl-tetrahydrothiopyraner eller deres syreadditionssalte
DK0763516T3 (da)	2001-09-17	Fremstilling og anvendelse af rene enantiomerer af 8-halogen-6-hydroxyoctansyrer, deres alkylestere og deres salte med rene enantiomerer af alfa-methylbenzylamin
SE8802162L (sv)	1988-12-13	Nya aminoacylater av glycerolacetal
DK320582A (da)	1983-01-19	Substituerede phenyl-cyclopropancarboxylsyreestere,fremgangsmaade til fremstilling deraf samt deres anvendelse som midler til bekaempelse af skadelige organismer
DK358486D0 (da)	1986-07-28	Fremgangsmaade til fremstilling af 2-acyl-3,4-dialkoxyaniliner
MX9804482A (es)	1998-12-31	Quinolinas y quinazolinas utiles en terapias.