DK69389A - Renin-haemmende aminosyrederivater og fysiologisk acceptable salte deraf, deres fremstilling og anvendelse - Google Patents
Renin-haemmende aminosyrederivater og fysiologisk acceptable salte deraf, deres fremstilling og anvendelseInfo
- Publication number
- DK69389A DK69389A DK069389A DK69389A DK69389A DK 69389 A DK69389 A DK 69389A DK 069389 A DK069389 A DK 069389A DK 69389 A DK69389 A DK 69389A DK 69389 A DK69389 A DK 69389A
- Authority
- DK
- Denmark
- Prior art keywords
- physially
- pure
- preparation
- amino acid
- acceptable salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Furan Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3804793A DE3804793A1 (de) | 1988-02-16 | 1988-02-16 | Renin-hemmende aminosaeurederivate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK69389D0 DK69389D0 (da) | 1989-02-15 |
| DK69389A true DK69389A (da) | 1989-08-17 |
Family
ID=6347510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK069389A DK69389A (da) | 1988-02-16 | 1989-02-15 | Renin-haemmende aminosyrederivater og fysiologisk acceptable salte deraf, deres fremstilling og anvendelse |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5204357A (da) |
| EP (1) | EP0329013A3 (da) |
| JP (1) | JPH023665A (da) |
| KR (1) | KR890013053A (da) |
| CN (1) | CN1035286A (da) |
| AU (1) | AU626535B2 (da) |
| DE (1) | DE3804793A1 (da) |
| DK (1) | DK69389A (da) |
| FI (1) | FI890699L (da) |
| HU (1) | HU203226B (da) |
| IL (1) | IL89304A0 (da) |
| NO (1) | NO890635L (da) |
| NZ (1) | NZ227976A (da) |
| PT (1) | PT89730B (da) |
| ZA (1) | ZA891135B (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3717631A1 (de) * | 1987-05-26 | 1988-12-15 | Merck Patent Gmbh | Aminosaeurederivate |
| ATE135368T1 (de) * | 1989-09-12 | 1996-03-15 | Hoechst Ag | Aminosäurederivate mit reninhemmenden eigenschaften, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung |
| EP0432974A1 (en) * | 1989-12-08 | 1991-06-19 | Merck & Co. Inc. | Cyclic renin inhibitors |
| US5330737A (en) * | 1991-12-06 | 1994-07-19 | Mallinckrodt Medical, Inc. | Nitrogen-sulfur ligands as opiate receptor drug mimics |
| US6455734B1 (en) * | 2000-08-09 | 2002-09-24 | Magnesium Diagnostics, Inc. | Antagonists of the magnesium binding defect as therapeutic agents and methods for treatment of abnormal physiological states |
| US9604930B2 (en) | 2012-12-21 | 2017-03-28 | Epizyme, Inc. | Tetrahydro- and dihydro-isoquinoline PRMT5 inhibitors and uses thereof |
| US10118918B2 (en) | 2012-12-21 | 2018-11-06 | Epizyme, Inc. | PRMT5 inhibitors and uses thereof |
| US9365555B2 (en) | 2012-12-21 | 2016-06-14 | Epizyme, Inc. | PRMT5 inhibitors and uses thereof |
| US9908887B2 (en) | 2012-12-21 | 2018-03-06 | Epizyme, Inc. | PRMT5 inhibitors and uses thereof |
| JP2016505002A (ja) | 2012-12-21 | 2016-02-18 | エピザイム,インコーポレイティド | ジヒドロイソキノリンまたはテトラヒドロイソキノリンを含有するprmt5阻害剤およびその使用 |
| AU2015301196A1 (en) | 2014-08-04 | 2017-01-12 | Epizyme, Inc. | PRMT5 inhibitors and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4435329A (en) * | 1981-10-16 | 1984-03-06 | American Cyanamid Company | Substituted N-(ω-aroylpropionyl) derivatives of α-amino acids and esters thereof |
| DE3467754D1 (de) * | 1983-10-03 | 1988-01-07 | Squibb & Sons Inc | Enkephalinase inhibitors |
| EP0236734A3 (de) * | 1986-02-07 | 1988-05-11 | Ciba-Geigy Ag | Durch schwefelhaltigen Gruppen substituierte 5-Amino-4-hydroxyvalerylderivate |
| DE3732971A1 (de) * | 1987-09-30 | 1989-04-20 | Hoechst Ag | Renin-hemmende dipeptide, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung |
-
1988
- 1988-02-16 DE DE3804793A patent/DE3804793A1/de not_active Withdrawn
-
1989
- 1989-02-09 EP EP19890102215 patent/EP0329013A3/de not_active Withdrawn
- 1989-02-14 FI FI890699A patent/FI890699L/fi not_active Application Discontinuation
- 1989-02-14 ZA ZA891135A patent/ZA891135B/xx unknown
- 1989-02-14 NZ NZ227976A patent/NZ227976A/xx unknown
- 1989-02-14 US US07/310,183 patent/US5204357A/en not_active Expired - Fee Related
- 1989-02-15 KR KR1019890001707A patent/KR890013053A/ko not_active Withdrawn
- 1989-02-15 CN CN89100812A patent/CN1035286A/zh active Pending
- 1989-02-15 DK DK069389A patent/DK69389A/da not_active Application Discontinuation
- 1989-02-15 NO NO89890635A patent/NO890635L/no unknown
- 1989-02-15 AU AU29977/89A patent/AU626535B2/en not_active Ceased
- 1989-02-15 JP JP1033895A patent/JPH023665A/ja active Pending
- 1989-02-15 HU HU89763A patent/HU203226B/hu not_active IP Right Cessation
- 1989-02-15 IL IL89304A patent/IL89304A0/xx not_active IP Right Cessation
- 1989-02-16 PT PT89730A patent/PT89730B/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ227976A (en) | 1991-12-23 |
| ZA891135B (en) | 1989-10-25 |
| DK69389D0 (da) | 1989-02-15 |
| HUT50789A (en) | 1990-03-28 |
| EP0329013A2 (de) | 1989-08-23 |
| PT89730B (pt) | 1994-03-31 |
| FI890699A7 (fi) | 1989-08-17 |
| IL89304A0 (en) | 1989-09-10 |
| EP0329013A3 (de) | 1991-03-13 |
| HU203226B (en) | 1991-06-28 |
| JPH023665A (ja) | 1990-01-09 |
| US5204357A (en) | 1993-04-20 |
| AU626535B2 (en) | 1992-08-06 |
| FI890699A0 (fi) | 1989-02-14 |
| NO890635L (no) | 1989-08-17 |
| DE3804793A1 (de) | 1989-08-24 |
| NO890635D0 (no) | 1989-02-15 |
| PT89730A (pt) | 1989-10-04 |
| CN1035286A (zh) | 1989-09-06 |
| KR890013053A (ko) | 1989-09-21 |
| AU2997789A (en) | 1989-08-17 |
| FI890699L (fi) | 1989-08-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |