DK7487A - Fremgangsmaade til paa bestilling at fremstille en homogen mikrokapselsuspension - Google Patents

Fremgangsmaade til paa bestilling at fremstille en homogen mikrokapselsuspension

Info

Publication number
DK7487A
DK7487A DK007487A DK7487A DK7487A DK 7487 A DK7487 A DK 7487A DK 007487 A DK007487 A DK 007487A DK 7487 A DK7487 A DK 7487A DK 7487 A DK7487 A DK 7487A
Authority
DK
Denmark
Prior art keywords
suspension
microcapsel
homogenic
ordering
make
Prior art date
Application number
DK007487A
Other languages
English (en)
Other versions
DK157730C (da
DK157730B (da
DK7487D0 (da
Inventor
Massimo Calanchi
Leonardo Gentilini
Marco Marconi
Original Assignee
Eurand Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurand Spa filed Critical Eurand Spa
Publication of DK7487D0 publication Critical patent/DK7487D0/da
Publication of DK7487A publication Critical patent/DK7487A/da
Publication of DK157730B publication Critical patent/DK157730B/da
Application granted granted Critical
Publication of DK157730C publication Critical patent/DK157730C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989—Microcapsule with solid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK007487A 1985-05-08 1987-01-07 Fremgangsmaade til fremstilling af et farmaceutisk mikrokapselpraeparat og praeparat fremstillet ved fremgangsmaaden DK157730C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IT20617/85A IT1183574B (it) 1985-05-08 1985-05-08 Metodo per ottenere una sospensione estemporanea omogenea di microcapsule
IT2061785 1985-05-08
EP8600280 1986-05-02
PCT/EP1986/000280 WO1986006626A1 (en) 1985-05-08 1986-05-02 Method of preparing an extemporaneous homogeneous microcapsule suspension

Publications (4)

Publication Number Publication Date
DK7487D0 DK7487D0 (da) 1987-01-07
DK7487A true DK7487A (da) 1987-01-07
DK157730B DK157730B (da) 1990-02-12
DK157730C DK157730C (da) 1990-07-16

Family

ID=11169617

Family Applications (1)

Application Number Title Priority Date Filing Date
DK007487A DK157730C (da) 1985-05-08 1987-01-07 Fremgangsmaade til fremstilling af et farmaceutisk mikrokapselpraeparat og praeparat fremstillet ved fremgangsmaaden

Country Status (19)

Country Link
US (1) US5008117A (da)
EP (1) EP0222856B1 (da)
JP (1) JP2609597B2 (da)
KR (1) KR900000212B1 (da)
AT (1) ATE59287T1 (da)
AU (1) AU589644B2 (da)
CA (1) CA1274144A (da)
DE (1) DE3676642D1 (da)
DK (1) DK157730C (da)
ES (1) ES8707103A1 (da)
FI (1) FI86596C (da)
HU (1) HUT44168A (da)
IT (1) IT1183574B (da)
NO (1) NO171949C (da)
NZ (1) NZ216062A (da)
PT (1) PT82541B (da)
RU (1) RU2059409C1 (da)
WO (1) WO1986006626A1 (da)
ZA (1) ZA863399B (da)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8628359D0 (en) * 1986-11-27 1986-12-31 Zyma Sa Galenical formulation
GB8702411D0 (en) * 1987-02-03 1987-03-11 Zyma Sa Swellable pellets
US5064650A (en) * 1988-04-19 1991-11-12 Southwest Research Institute Controlled-release salt sensitive capsule for oral use and adhesive system
JPH03504968A (ja) * 1988-04-19 1991-10-31 サウスウェスト・リサーチ・インスティチュート 塩感受性シェル物質を有するカプセルからの活性成分の制御放出
FR2634376B1 (fr) * 1988-07-21 1992-04-17 Farmalyoc Nouvelle forme unitaire, solide et poreuse comprenant des microparticules et/ou des nanoparticules, ainsi que sa preparation
NZ234143A (en) * 1989-06-28 1991-10-25 Mcneil Ppc Inc Aqueous pharmaceutical suspension formulation for administering substantially insoluble pharmaceutical agents
US5112604A (en) * 1989-09-01 1992-05-12 Riker Laboratories, Inc. Oral suspension formulation
IT1246350B (it) * 1990-07-11 1994-11-17 Eurand Int Metodo per ottenere una rapida sospensione in acqua di farmaci insolubili
US5300302A (en) * 1990-10-04 1994-04-05 Nestec S.A. Pharmaceutical composition in gel form in a dispensing package
US5252337A (en) * 1991-06-25 1993-10-12 Eurand America, Inc. Controlled release calcium channel blocker microcapsules
US5599556A (en) * 1991-12-31 1997-02-04 Abbott Laboratories Prolamine coatings for taste masking
US5272137A (en) * 1992-02-14 1993-12-21 Mcneil-Pfc, Inc. Aqueous pharmaceutical suspension for pharmaceutical actives
EP0633907A1 (en) * 1992-03-30 1995-01-18 Alza Corporation Additives for bioerodible polymers to regulate degradation
ZA932272B (en) * 1992-03-30 1993-10-19 Alza Corp Viscous suspensions of controlled-release drug particles
ES2099438T3 (es) * 1992-04-30 1997-05-16 Schering Corp Polvo seco y estable de cefalosporina hidratada para formulacion de suspension oral.
US5422122A (en) * 1992-08-04 1995-06-06 Eurand America, Incorporated Controlled release potassium chloride tablet
US5981719A (en) 1993-03-09 1999-11-09 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
NO941358L (no) * 1993-04-16 1994-10-17 Mcneil Ppc Inc Vandig farmasöytisk suspensjon og fremgangsmåte for fremstilling derav
GB2318511A (en) * 1996-10-23 1998-04-29 Eurand Int Process for the preparation of a pharmaceutical composition for rapid suspension in water
RU2147923C1 (ru) * 1997-12-02 2000-04-27 Ивановский государственный университет Способ получения микрокапсул
UA65607C2 (uk) 1998-03-04 2004-04-15 Орто-Макнейл Фармацевтикал, Інк. Фармацевтична композиція (варіанти) та спосіб її приготування
GB9822170D0 (en) * 1998-10-13 1998-12-02 Danbioyst Uk Ltd Novel formulations of fexofenadine
US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6159491A (en) * 1999-02-12 2000-12-12 Biovector Technologies, Inc. Prolonged release bioadhesive vaginal gel dosage form
US6500462B1 (en) * 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
TR200300731T2 (tr) 2000-11-28 2004-08-23 Fmc Corporation Yenebilir PGA kaplama bileşimi
US6932861B2 (en) 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
CA2431319A1 (en) * 2000-12-11 2002-06-20 Hiroto Bando Pharmaceutical composition having an improved water solubility
JP2004168703A (ja) * 2002-11-20 2004-06-17 Shin Etsu Chem Co Ltd マイクロカプセル及びその製造方法
US20040170686A1 (en) * 2003-01-31 2004-09-02 Fredrickson Jennifer K. Suspension vehicle for coated drug particles
US20040191326A1 (en) * 2003-03-31 2004-09-30 Reo Joseph P. Taste-masking vehicle for coated oxazolidinone particles
US7632521B2 (en) * 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
US20050118194A1 (en) * 2003-12-01 2005-06-02 Sin Yoke M. Oral vaccine, method for its preparation and use thereof
US20060134210A1 (en) * 2004-12-22 2006-06-22 Astrazeneca Ab Solid dosage form comprising proton pump inhibitor and suspension made thereof
EP3568122B1 (en) * 2017-01-10 2023-10-04 Dukebox SP. Z O.O. A method of manufacturing a suspension of nanoparticles of potassium salt or magnesium salt
AU2020225818B2 (en) 2019-02-22 2025-09-18 Catalent U.K. Swindon Zydis Limited Preserving functionally-coated API particles produced by solventless mixing processes in aqueous suspension
WO2020169989A1 (en) 2019-02-22 2020-08-27 Catalent U.K. Swindon Zydis Limited Minimizing agglomeration, aeration, and preserving the coating of pharmaceutical compositions comprising ibuprofen
KR20210130144A (ko) * 2019-02-22 2021-10-29 카탈렌트 유.케이. 스윈던 지디스 리미티드 인-라인 혼합 동안 현탁액의 에어레이션 최소화
US11141380B2 (en) 2019-02-22 2021-10-12 Catalent U.K. Swindon Zydis Limited Minimizing agglomeration of drug particle coating material during storage to stabilize disintegration times of pharmaceutical products
RU2731599C1 (ru) * 2019-07-17 2020-09-04 Общество с ограниченной ответственностью "РУСИНТЕХ" Способ получения микрокапсулированного термоактивируемого огнегасящего агента
WO2022024066A1 (en) 2020-07-31 2022-02-03 Catalent U.K. Swindon Zydis Limited Pharmaceutical compositions comprising coated api

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB844772A (en) * 1956-04-19 1960-08-17 Pfizer & Co C Granular pharmaceutical compositions and process for preparing same
FR2077696B1 (da) * 1970-02-06 1973-03-16 Synthelabo
DE2211019C3 (de) * 1972-03-08 1980-08-28 Bayer Ag, 5090 Leverkusen Geschmacksverbessernde Formulierungen oraler Penicilline
US4155741A (en) * 1974-05-01 1979-05-22 Stauffer Chemical Company Stable suspension system for microencapsulated flowable formulations, and method of preparing stable suspension of microcapsules
US4126672A (en) * 1976-02-04 1978-11-21 Hoffmann-La Roche Inc. Sustained release pharmaceutical capsules
US4189499A (en) * 1977-03-16 1980-02-19 Biochefarm S.A. Lysine 4-allyloxy-3-chlorophenylacetate and method of its preparation
IT1148784B (it) * 1980-04-09 1986-12-03 Eurand Spa Procedimento per la preparazione di microcapsule in un veicolo liquido
IT1209276B (it) * 1980-11-05 1989-07-16 Magis Farmaceutici Composizione farmaceutica per la somministrazione orale del metilestere dell'acido 13a-etil-2,3,5,6,12,13,13a,13b-ottaidro-12-idrossi1h-indolo-[3,2,1-de] pirido [3,2,1-ij] [1,5] naftiridina -12-carbossilico

Also Published As

Publication number Publication date
NO171949B (no) 1993-02-15
ES8707103A1 (es) 1987-07-16
JP2609597B2 (ja) 1997-05-14
ATE59287T1 (de) 1991-01-15
FI865336L (fi) 1986-12-30
AU589644B2 (en) 1989-10-19
FI865336A0 (fi) 1986-12-30
HUT44168A (en) 1988-02-29
FI86596C (fi) 1992-09-25
AU5903186A (en) 1986-12-04
DK157730C (da) 1990-07-16
EP0222856B1 (en) 1990-12-27
JPS62502859A (ja) 1987-11-12
EP0222856A1 (en) 1987-05-27
US5008117A (en) 1991-04-16
ES554777A0 (es) 1987-07-16
NO865162L (no) 1986-12-18
IT1183574B (it) 1987-10-22
IT8520617A0 (it) 1985-05-08
FI86596B (fi) 1992-06-15
PT82541A (en) 1986-06-01
PT82541B (pt) 1988-03-03
CA1274144A (en) 1990-09-18
DK157730B (da) 1990-02-12
DE3676642D1 (de) 1991-02-07
KR900000212B1 (ko) 1990-01-23
WO1986006626A1 (en) 1986-11-20
DK7487D0 (da) 1987-01-07
NZ216062A (en) 1989-07-27
KR870700209A (ko) 1987-05-30
NO171949C (no) 1993-05-26
ZA863399B (en) 1987-01-28
RU2059409C1 (ru) 1996-05-10

Similar Documents

Publication Publication Date Title
DK7487A (da) Fremgangsmaade til paa bestilling at fremstille en homogen mikrokapselsuspension
NO871361D0 (no) Fremgangsmaate for redusering av fluidtap i sementsammensetninger som kan inneholde vesentlige saltkonsentrasjoner.
NO965523L (no) Filtrering
IT8619344A0 (it) Procedimento di purificazione di proteine del latte e di suoi derivati.
FI861515A7 (fi) Peritoneaalidialyysilaite ja sen liitin.
FR2553293B1 (fr) Procede pour empecher l'encrassement d'une membrane d'electrodialyse dans la desalinisation d'une solution aqueuse
DE3680984D1 (de) Fleischprodukte in form von krabbenbeinen und verfahren zu ihrer herstellung.
DE3682661D1 (de) System zur parenteralen verabreichung von fluessigkeiten.
BR8704486A (pt) Aditivo,concentrado de aditivo e fluido aquoso isento de oleo
NO873081D0 (no) Termoplastiske preparater med meget hoeyt innhold av pulverformige mineralstoffer.
DE3679714D1 (de) Stabilisierung von tee in kaltem wasser.
ES2021732B3 (es) Procedimiento y dispositivo de tratamiento de fluidos que contienen particulas en suspension.
DE3779063D1 (de) Verfahren zur stabilisierung von waesserigen phosphoenolbrenztraubensaeureloesungen und container dafuer.
DK313486D0 (da) Fremgangsmaade til koncentrering af overfladeaktive midler i en oploesning indeholdende samme og vand eller saltvand
NO882255L (no) Fremgangsmaate for fremstilling av olefin-maleinsyreanhydrid-kopolymer i form av partikler.
JPS57132508A (en) Protein flocculating agent using seaweeds extract as raw material
IT8447914A1 (it) Procedimento per impedire la gelificazione di soluzioni acquose concentrate di fotoattivatori e soluzioni cosi' ottenute.
RO94652A (ro) Procedeu pentru prepararea unei solutii apoase de polizaharida
BR6601358U (pt) Disposicoes introduzidas no agrupamento de dois ou mais filtros de piscinas,para poder funcionar em paralelo
FI821476A7 (fi) Selektiivinen hapetusjärjestelmä ja sen soveltaminen ortodihydroksiloitujen tai ortodialkoksiloitujen aromaattisten johdannaisten valmistuksessa.
FI884293A7 (fi) Menetelmä mikro-organismien kasvun estämiseksi vesipitoisissa nesteissä.
ES2001620A6 (es) Procedimiento para la obtencion de una solucion a base de luprostiol
NO862740D0 (no) Fremgangsmaate for stabilisering av xantangummi i vandig loesning.
RU92016552A (ru) Очистка водной жидкости
DE3770888D1 (de) Ph- und waermestabile subtilisinanaloge und deren herstellung.

Legal Events

Date Code Title Description
PBP Patent lapsed

Country of ref document: DK