DK157730C - Fremgangsmaade til fremstilling af et farmaceutisk mikrokapselpraeparat og praeparat fremstillet ved fremgangsmaaden - Google Patents

Fremgangsmaade til fremstilling af et farmaceutisk mikrokapselpraeparat og praeparat fremstillet ved fremgangsmaaden

Info

Publication number
DK157730C
DK157730C DK007487A DK7487A DK157730C DK 157730 C DK157730 C DK 157730C DK 007487 A DK007487 A DK 007487A DK 7487 A DK7487 A DK 7487A DK 157730 C DK157730 C DK 157730C
Authority
DK
Denmark
Prior art keywords
preparation
procedure
microcasple
pharmaceutical
prepared
Prior art date
Application number
DK007487A
Other languages
English (en)
Other versions
DK7487D0 (da
DK157730B (da
DK7487A (da
Inventor
Massimo Calanchi
Leonardo Gentilini
Marco Marconi
Original Assignee
Eurand Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eurand Spa filed Critical Eurand Spa
Publication of DK7487D0 publication Critical patent/DK7487D0/da
Publication of DK7487A publication Critical patent/DK7487A/da
Publication of DK157730B publication Critical patent/DK157730B/da
Application granted granted Critical
Publication of DK157730C publication Critical patent/DK157730C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989—Microcapsule with solid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK007487A 1985-05-08 1987-01-07 Fremgangsmaade til fremstilling af et farmaceutisk mikrokapselpraeparat og praeparat fremstillet ved fremgangsmaaden DK157730C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IT20617/85A IT1183574B (it) 1985-05-08 1985-05-08 Metodo per ottenere una sospensione estemporanea omogenea di microcapsule
IT2061785 1985-05-08
EP8600280 1986-05-02
PCT/EP1986/000280 WO1986006626A1 (en) 1985-05-08 1986-05-02 Method of preparing an extemporaneous homogeneous microcapsule suspension

Publications (4)

Publication Number Publication Date
DK7487D0 DK7487D0 (da) 1987-01-07
DK7487A DK7487A (da) 1987-01-07
DK157730B DK157730B (da) 1990-02-12
DK157730C true DK157730C (da) 1990-07-16

Family

ID=11169617

Family Applications (1)

Application Number Title Priority Date Filing Date
DK007487A DK157730C (da) 1985-05-08 1987-01-07 Fremgangsmaade til fremstilling af et farmaceutisk mikrokapselpraeparat og praeparat fremstillet ved fremgangsmaaden

Country Status (19)

Country Link
US (1) US5008117A (da)
EP (1) EP0222856B1 (da)
JP (1) JP2609597B2 (da)
KR (1) KR900000212B1 (da)
AT (1) ATE59287T1 (da)
AU (1) AU589644B2 (da)
CA (1) CA1274144A (da)
DE (1) DE3676642D1 (da)
DK (1) DK157730C (da)
ES (1) ES8707103A1 (da)
FI (1) FI86596C (da)
HU (1) HUT44168A (da)
IT (1) IT1183574B (da)
NO (1) NO171949C (da)
NZ (1) NZ216062A (da)
PT (1) PT82541B (da)
RU (1) RU2059409C1 (da)
WO (1) WO1986006626A1 (da)
ZA (1) ZA863399B (da)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8628359D0 (en) * 1986-11-27 1986-12-31 Zyma Sa Galenical formulation
GB8702411D0 (en) * 1987-02-03 1987-03-11 Zyma Sa Swellable pellets
US5064650A (en) * 1988-04-19 1991-11-12 Southwest Research Institute Controlled-release salt sensitive capsule for oral use and adhesive system
JPH03504968A (ja) * 1988-04-19 1991-10-31 サウスウェスト・リサーチ・インスティチュート 塩感受性シェル物質を有するカプセルからの活性成分の制御放出
FR2634376B1 (fr) 1988-07-21 1992-04-17 Farmalyoc Nouvelle forme unitaire, solide et poreuse comprenant des microparticules et/ou des nanoparticules, ainsi que sa preparation
NZ234143A (en) * 1989-06-28 1991-10-25 Mcneil Ppc Inc Aqueous pharmaceutical suspension formulation for administering substantially insoluble pharmaceutical agents
US5112604A (en) * 1989-09-01 1992-05-12 Riker Laboratories, Inc. Oral suspension formulation
IT1246350B (it) * 1990-07-11 1994-11-17 Eurand Int Metodo per ottenere una rapida sospensione in acqua di farmaci insolubili
US5300302A (en) * 1990-10-04 1994-04-05 Nestec S.A. Pharmaceutical composition in gel form in a dispensing package
US5252337A (en) * 1991-06-25 1993-10-12 Eurand America, Inc. Controlled release calcium channel blocker microcapsules
US5599556A (en) * 1991-12-31 1997-02-04 Abbott Laboratories Prolamine coatings for taste masking
US5272137A (en) * 1992-02-14 1993-12-21 Mcneil-Pfc, Inc. Aqueous pharmaceutical suspension for pharmaceutical actives
MX9301821A (es) * 1992-03-30 1994-03-31 Alza Corp Sistema de matriz polimerica biodegradable regulador de degradacion y metodo de tratamiento del mismo.
WO1993019739A1 (en) * 1992-03-30 1993-10-14 Alza Corporation Viscous suspensions of controlled-release drug particles
CZ283428B6 (cs) * 1992-04-30 1998-04-15 Schering Corporation Stabilní hydratovaný suchý práškový cefalosporin vhodný pro orální aplikaci ve formě suspenze
US5422122A (en) * 1992-08-04 1995-06-06 Eurand America, Incorporated Controlled release potassium chloride tablet
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US5981719A (en) 1993-03-09 1999-11-09 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
FI941777A7 (fi) * 1993-04-16 1994-10-17 Mcneil Ppc Inc Vesipitoinen farmaseuttinen suspensio ja menetelmä sen valmistamiseksi
GB2318511A (en) * 1996-10-23 1998-04-29 Eurand Int Process for the preparation of a pharmaceutical composition for rapid suspension in water
RU2147923C1 (ru) * 1997-12-02 2000-04-27 Ивановский государственный университет Способ получения микрокапсул
UA65607C2 (uk) * 1998-03-04 2004-04-15 Орто-Макнейл Фармацевтикал, Інк. Фармацевтична композиція (варіанти) та спосіб її приготування
GB9822170D0 (en) * 1998-10-13 1998-12-02 Danbioyst Uk Ltd Novel formulations of fexofenadine
US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6159491A (en) * 1999-02-12 2000-12-12 Biovector Technologies, Inc. Prolonged release bioadhesive vaginal gel dosage form
US6500462B1 (en) 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
US6932861B2 (en) * 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
BR0115585A (pt) 2000-11-28 2005-12-13 Fmc Corp Composições de revestimento de pronta liberação, endurecìvel, comestìvel, seca e, úmida, forma de dosagem sólida, e, método para revestir uma forma de dosagem sólida farmacêutica ou veterinária, confeito, semente, ração animal, fertilizante, comprimido de pesticida ou alimento
PL362979A1 (en) * 2000-12-11 2004-11-02 Takeda Chemical Industries, Ltd. Medicinal compositions improved in solublity in water
JP2004168703A (ja) * 2002-11-20 2004-06-17 Shin Etsu Chem Co Ltd マイクロカプセル及びその製造方法
US20040170686A1 (en) * 2003-01-31 2004-09-02 Fredrickson Jennifer K. Suspension vehicle for coated drug particles
US20040191326A1 (en) * 2003-03-31 2004-09-30 Reo Joseph P. Taste-masking vehicle for coated oxazolidinone particles
US7632521B2 (en) * 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
US20050118194A1 (en) * 2003-12-01 2005-06-02 Sin Yoke M. Oral vaccine, method for its preparation and use thereof
US20060134210A1 (en) * 2004-12-22 2006-06-22 Astrazeneca Ab Solid dosage form comprising proton pump inhibitor and suspension made thereof
PL3568122T3 (pl) * 2017-01-10 2024-03-18 Dukebox Sp. Z O.O. Sposób wytwarzania zawiesiny nanocząsteczek soli potasowej albo soli magnezowej
KR20210129649A (ko) 2019-02-22 2021-10-28 카탈렌트 유.케이. 스윈던 지디스 리미티드 이부프로펜을 포함하는 약학적 조성물의 응집, 에어레이션 최소화 및 코팅 보존
AU2020225818B2 (en) 2019-02-22 2025-09-18 Catalent U.K. Swindon Zydis Limited Preserving functionally-coated API particles produced by solventless mixing processes in aqueous suspension
JP7543291B2 (ja) 2019-02-22 2024-09-02 キャタレント・ユーケー・スウィンドン・ザイディス・リミテッド 医薬品の崩壊時間を安定させるための、保管中の薬物粒子コーティング材料の凝集を最小限に抑える
ES2961850T3 (es) * 2019-02-22 2024-03-14 Catalent Uk Swindon Zydis Ltd Minimización de la aireación de suspensiones durante la mezcla en línea
RU2731599C1 (ru) * 2019-07-17 2020-09-04 Общество с ограниченной ответственностью "РУСИНТЕХ" Способ получения микрокапсулированного термоактивируемого огнегасящего агента
US12208160B2 (en) 2020-07-31 2025-01-28 Catalent U.K. Swindon Zydis Limited Pharmaceutical compositions comprising coated API

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB844772A (en) * 1956-04-19 1960-08-17 Pfizer & Co C Granular pharmaceutical compositions and process for preparing same
FR2077696B1 (da) * 1970-02-06 1973-03-16 Synthelabo
DE2211019C3 (de) * 1972-03-08 1980-08-28 Bayer Ag, 5090 Leverkusen Geschmacksverbessernde Formulierungen oraler Penicilline
US4155741A (en) * 1974-05-01 1979-05-22 Stauffer Chemical Company Stable suspension system for microencapsulated flowable formulations, and method of preparing stable suspension of microcapsules
US4126672A (en) * 1976-02-04 1978-11-21 Hoffmann-La Roche Inc. Sustained release pharmaceutical capsules
US4189499A (en) * 1977-03-16 1980-02-19 Biochefarm S.A. Lysine 4-allyloxy-3-chlorophenylacetate and method of its preparation
IT1148784B (it) * 1980-04-09 1986-12-03 Eurand Spa Procedimento per la preparazione di microcapsule in un veicolo liquido
IT1209276B (it) * 1980-11-05 1989-07-16 Magis Farmaceutici Composizione farmaceutica per la somministrazione orale del metilestere dell'acido 13a-etil-2,3,5,6,12,13,13a,13b-ottaidro-12-idrossi1h-indolo-[3,2,1-de] pirido [3,2,1-ij] [1,5] naftiridina -12-carbossilico

Also Published As

Publication number Publication date
AU5903186A (en) 1986-12-04
ZA863399B (en) 1987-01-28
PT82541A (en) 1986-06-01
KR870700209A (ko) 1987-05-30
DK7487D0 (da) 1987-01-07
NZ216062A (en) 1989-07-27
KR900000212B1 (ko) 1990-01-23
NO171949B (no) 1993-02-15
DK157730B (da) 1990-02-12
FI86596B (fi) 1992-06-15
WO1986006626A1 (en) 1986-11-20
ATE59287T1 (de) 1991-01-15
EP0222856B1 (en) 1990-12-27
ES554777A0 (es) 1987-07-16
RU2059409C1 (ru) 1996-05-10
PT82541B (pt) 1988-03-03
FI865336A0 (fi) 1986-12-30
JPS62502859A (ja) 1987-11-12
CA1274144A (en) 1990-09-18
EP0222856A1 (en) 1987-05-27
US5008117A (en) 1991-04-16
DK7487A (da) 1987-01-07
JP2609597B2 (ja) 1997-05-14
IT1183574B (it) 1987-10-22
FI86596C (fi) 1992-09-25
FI865336L (fi) 1986-12-30
HUT44168A (en) 1988-02-29
DE3676642D1 (de) 1991-02-07
IT8520617A0 (it) 1985-05-08
ES8707103A1 (es) 1987-07-16
NO865162L (no) 1986-12-18
NO171949C (no) 1993-05-26
AU589644B2 (en) 1989-10-19

Similar Documents

Publication Publication Date Title
DK157730C (da) Fremgangsmaade til fremstilling af et farmaceutisk mikrokapselpraeparat og praeparat fremstillet ved fremgangsmaaden
DK158718C (da) Fremgangsmaade til flokkulation af suspenderede faste stoffer i en vandig suspension
ES2060107T3 (es) Nuevo procedimiento de preparacion de microparticulas lipidicas.
DK160430C (da) Stabile salte af s-adenosyl-l-methionin med polyanioniske materialer, fremgangsmaade til fremstilling af disse samt farmaceutiske praeparater indeholdende disse
NZ504017A (en) Preparation of gatifloxacin and disodium edetate
DK280789D0 (da) Komplekser af beta-cyclodextrin med salte af ibuprofen, fremgangsmaade til fremstilling af saadanne komplekser og farmaceutiske midler indeholdende disse
FI891332A0 (fi) Akrylaatipolymeerin vesidispersioita ja menetelmä niiden valmistamiseksi
DE3688114D1 (de) Inklusionskomplexe von 7-isopropoxy-isoflavon mit cyclodextrinen, verfahren zu deren herstellung und diese inklusionskomplexe enthaltende pharmazeutische praeparate.
BR9609614A (pt) Composição e processos para prover pelo menos uma dentre a coagulação e a despegajosidade de partículas sólidas em suspensão em um sistema aquoso para desemulsificar um emulsão oleo-em-água
NO881625L (no) Fremgangsmaate for fremstilling av stabile sucralfatsuspensjoner.
NO169189C (no) Blanding paa basis av biopolymerer, fremgangsmaate for deres fremstilling og anvendelse av blandingen
FI852851A7 (fi) Mevalonolaktonin naftyylianalogeja ja niiden johdannaisia, menetelmiä niiden valmistamiseksi ja niiden käytt
BR9904286A (pt) Suspensões antiácidas e antigás termoestáveis
DE3585293D1 (de) Stabile suspension von pigmenten in waessrigen hypochlorid-bleichmittel-zusammensetzungen.
AR016869A1 (es) Metodo para preparar una suspension farmaceutica acuosa de nevirapina, dicha suspension farmaceutica y uso de nevirapina para preparar dicha suspensionfarmaceutica
DK565486A (da) Carboxylgruppeholdige polyamider, fremgangsmaader til fremstilling heraf samt deres anvendelse til fremstilling af vandige bronzedispersioner
FI831914A7 (fi) Pyrimidinonien ja niiden happoadditiosuolojen valmistusmenetelmät.
DK164588A (da) Fremgangsmaade til sterilisering af en vandig suspension af et uoploeseligt salt i vand
DK319384D0 (da) 1-0-alkyl-3-amino-propan-1,2-diol-2-0-phospholipider, fremgangsmaade til deres fremstilling samt farmaceutiske praeparater indeholdende disse
FR2657010B1 (fr) Composition pharmaceutique sous forme de suspension aqueuse stable a base de sucrafalte et d'une substance anti-acide ainsi que son procede de preparation.
IT8723050A0 (it) Procedimento per la preparazione di sospensioni fluide stabili ed induribili e composizioni cosi'ottenute.
Swislocki et al. Effects of pentoxifylline on Ca2+‐dependent transglutaminase in rat erythrocytes
GR890100737A (el) Μέ?οδος παρασκευής μιας φαρμακευτικής συν?έσεως δι'οφ?αλμική χρήσιν η οποία περιλαμβάνει ένα υδατοδιαλυτό άλας δια προσ?ήκης οξέος ιμποπαμίνης.
IT8620295A0 (it) Sospensione acquosa di carbone e relativi procedimenti di preparazione.
NO863735L (no) Fremgangsmaate for fremstilling av ranitidin eller syreaddisjonssalter derav.

Legal Events

Date Code Title Description
PBP Patent lapsed

Country of ref document: DK