DK95291A - Rekombinante dna-molekyler - Google Patents

Rekombinante dna-molekyler Download PDF

Info

Publication number: DK95291A
Authority: DK; Denmark
Prior art keywords: dna molecules; polypeptides; carrier protein; human; processes
Prior art date: 1988-12-22

Application number

DK095291A

Other languages

English (en)

Other versions

DK95291D0 (da

Inventor

Emerald Martin Spencer

Carol Talkingtonverser

Original Assignee

Biogrowth Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-12-22

Filing date

1991-05-21

Publication date

1991-08-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23115154&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK95291(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1991-05-21 Application filed by Biogrowth Inc filed Critical Biogrowth Inc

1991-05-21 Publication of DK95291D0 publication Critical patent/DK95291D0/da

1991-08-16 Publication of DK95291A publication Critical patent/DK95291A/da

Links

108020004511 Recombinant DNA Proteins 0.000 title abstract 4
229920001184 polypeptide Polymers 0.000 abstract 7
102000004196 processed proteins & peptides Human genes 0.000 abstract 7
108090000765 processed proteins & peptides Proteins 0.000 abstract 7
108090000723 Insulin-Like Growth Factor I Proteins 0.000 abstract 5
102000013275 Somatomedins Human genes 0.000 abstract 5
238000000034 method Methods 0.000 abstract 5
102000014914 Carrier Proteins Human genes 0.000 abstract 4
108010078791 Carrier Proteins Proteins 0.000 abstract 4
108020004414 DNA Proteins 0.000 abstract 4
230000004071 biological effect Effects 0.000 abstract 1
238000011210 chromatographic step Methods 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
210000002966 serum Anatomy 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4743—Insulin-like growth factor binding protein
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Physical Education & Sports Medicine (AREA)
Obesity (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Orthopedic Medicine & Surgery (AREA)
Hematology (AREA)
Rheumatology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Ophthalmology & Optometry (AREA)
Nutrition Science (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

DK095291A 1988-12-22 1991-05-21 Rekombinante dna-molekyler DK95291A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US29025088A	1988-12-22	1988-12-22
PCT/US1989/005791 WO1990006950A1 (en)	1988-12-22	1989-12-21	Recombinant dna molecules, hosts, processes and human somatomedin carrier protein-like polypeptides

Publications (2)

Publication Number	Publication Date
DK95291D0 DK95291D0 (da)	1991-05-21
DK95291A true DK95291A (da)	1991-08-16

Family

ID=23115154

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK095291A DK95291A (da)	1988-12-22	1991-05-21	Rekombinante dna-molekyler

Country Status (13)

Country	Link
EP (2)	EP0451194B1 (da)
JP (2)	JPH04503352A (da)
KR (1)	KR910700261A (da)
AT (1)	ATE155793T1 (da)
AU (1)	AU4836890A (da)
CA (1)	CA2006322C (da)
DE (1)	DE68928203T2 (da)
DK (1)	DK95291A (da)
ES (1)	ES2107422T3 (da)
GR (1)	GR3025094T3 (da)
IL (1)	IL92816A0 (da)
WO (1)	WO1990006950A1 (da)
ZA (1)	ZA899832B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5258287A (en) *	1988-03-22	1993-11-02	Genentech, Inc.	DNA encoding and methods of production of insulin-like growth factor binding protein BP53
US5198340A (en) *	1991-01-17	1993-03-30	Genentech, Inc.	Assay for free igf-i, igf-ii, and gh levels in body fluids
US5187151A (en) *	1991-02-12	1993-02-16	Genentech, Inc.	Use of binding protein with igf-i as an anabolic growth promoting agent
US5643867A (en) *	1992-08-26	1997-07-01	Celtrix Pharmaceuticals, Inc.	Method for treating catabolic conditions
AU713275B2 (en) *	1994-07-20	1999-11-25	Celtrix Pharmaceuticals, Inc.	IGF/IGFBP complex for promoting bone formation and for regulating bone remodeling
US5565204A (en) *	1994-08-24	1996-10-15	American Cyanamid Company	Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections
US6121416A (en)	1997-04-04	2000-09-19	Genentech, Inc.	Insulin-like growth factor agonist molecules
US6420518B1 (en)	1997-04-04	2002-07-16	Genetech, Inc.	Insulin-like growth factor agonist molecules
IL143834A0 (en)	1999-01-06	2002-04-21	Genentech Inc	Insulin-like growth factor (igf) i mutant variants
DE60016560T2 (de)	1999-01-06	2005-12-15	Genentech, Inc., South San Francisco	Mutierte variante des insulin-ähnlichen wachstumsfaktor-i (igf-i)
DE60133271T2 (de)	2000-05-16	2009-04-23	Genentech, Inc., South San Francisco	Behandlung von knorpelerkrankungen
WO2002072780A2 (en)	2001-03-14	2002-09-19	Genentech, Inc.	Igf antagonist peptides
ES2527871T3 (es)	2003-05-01	2015-02-02	Imclone Llc	Anticuerpos completamente humanos dirigidos contra el receptor del factor de crecimiento 1 similar a la insulina humana
ATE536186T1 (de)	2003-09-12	2011-12-15	Tercica Inc	Verfahren zur behandlung von igf-1 (insulin-like growth factor 1)-mangel
CA2541015A1 (en)	2003-10-03	2005-04-14	Genentech, Inc.	Igf binding proteins
JP2009501141A (ja)	2005-06-17	2009-01-15	イムクローンシステムズインコーポレイテッド	転移性骨癌の治療のための受容体アンタゴニスト
EA017265B1 (ru)	2006-02-03	2012-11-30	Имклоун Элэлси	Применение антитела imc-a12, которое является ингибитором igf-ir, для лечения рака предстательной железы
IL273174B2 (en)	2017-09-11	2024-12-01	Shire Human Genetic Therapies	Insulin-like growth factor-1 (igf-1) for use in treating chronic lung diseases
PT4228676T (pt)	2020-10-19	2025-01-24	Oak Hill Bio Ltd	Composições adequadas para utilização em recém-nascidos
WO2023139115A1 (en)	2022-01-19	2023-07-27	Oak Hill Bio Limited	Compositions and methods for reducing oxidation of igf‐1/igfbp
WO2023242439A1 (en)	2022-06-17	2023-12-21	Oak Hill Bio Limited	Vascular stabilisation (preterm infants)
WO2023242442A1 (en)	2022-06-17	2023-12-21	Oak Hill Bio Limited	Method of maturing/differentiating neurons and/or modulating the vagus nerve
WO2023242440A1 (en)	2022-06-17	2023-12-21	Oak Hill Bio Limited	Treament of lungs in infants
AU2024220592A1 (en)	2023-02-14	2025-07-03	Ann and Robert Lurie Children's Hospital of Chicago	Treatment of healing dysregulation in gi tissue

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL68218A (en) *	1983-03-23	1985-12-31	Univ Ramot	Compositions for cartilage repair comprising embryonal chondrocytes
US4738921A (en) *	1984-09-27	1988-04-19	Eli Lilly And Company	Derivative of the tryptophan operon for expression of fused gene products
CA1322714C (en) *	1986-11-14	1993-10-05	Harry N. Antoniades	Wound healing and bone regeneration
US4885163A (en) *	1987-02-24	1989-12-05	Eli Lilly And Company	Topical use of IGF-II for wound healing
US5057417A (en) *	1987-06-12	1991-10-15	Genentech, Inc.	Compositions and methods for the synthesis of growth hormone receptor and growth hormone binding protein
NZ228370A (en) *	1988-03-17	1994-01-26	Novo Nordisk As	Heparin-binding protein and preparation thereof.
US5258287A (en) *	1988-03-22	1993-11-02	Genentech, Inc.	DNA encoding and methods of production of insulin-like growth factor binding protein BP53
ATE132164T1 (de) *	1988-04-12	1996-01-15	Amgen Boulder Inc	Verfahren zur steigerung und zur hemmung der wirkung eines insulinähnlichen wachstumfaktors

1989
- 1989-12-20 IL IL92816A patent/IL92816A0/xx unknown
- 1989-12-21 DE DE68928203T patent/DE68928203T2/de not_active Revoked
- 1989-12-21 JP JP2501912A patent/JPH04503352A/ja active Pending
- 1989-12-21 WO PCT/US1989/005791 patent/WO1990006950A1/en not_active Ceased
- 1989-12-21 AU AU48368/90A patent/AU4836890A/en not_active Abandoned
- 1989-12-21 ES ES90901407T patent/ES2107422T3/es not_active Expired - Lifetime
- 1989-12-21 CA CA002006322A patent/CA2006322C/en not_active Expired - Fee Related
- 1989-12-21 ZA ZA899832A patent/ZA899832B/xx unknown
- 1989-12-21 AT AT90901407T patent/ATE155793T1/de not_active IP Right Cessation
- 1989-12-21 EP EP90901407A patent/EP0451194B1/en not_active Revoked
- 1989-12-21 KR KR1019900701824A patent/KR910700261A/ko not_active Withdrawn
- 1989-12-21 EP EP19890313463 patent/EP0375438A3/en active Pending
1991
- 1991-05-21 DK DK095291A patent/DK95291A/da unknown
1997
- 1997-10-20 GR GR970402735T patent/GR3025094T3/el unknown
1998
- 1998-10-23 JP JP10303047A patent/JPH11236400A/ja active Pending

Also Published As

Publication number	Publication date
ZA899832B (en)	1990-10-31
DE68928203D1 (de)	1997-09-04
EP0375438A3 (en)	1992-03-25
HK1000826A1 (en)	1998-05-01
JPH11236400A (ja)	1999-08-31
CA2006322C (en)	2000-08-01
EP0375438A2 (en)	1990-06-27
DK95291D0 (da)	1991-05-21
KR910700261A (ko)	1991-03-14
JPH04503352A (ja)	1992-06-18
AU4836890A (en)	1990-07-10
EP0451194A4 (en)	1992-09-02
EP0451194A1 (en)	1991-10-16
CA2006322A1 (en)	1990-06-22
EP0451194B1 (en)	1997-07-23
DE68928203T2 (de)	1998-01-15
IL92816A0 (en)	1990-09-17
WO1990006950A1 (en)	1990-06-28
ATE155793T1 (de)	1997-08-15
GR3025094T3 (en)	1998-01-30
ES2107422T3 (es)	1997-12-01

Publication	Publication Date	Title
DK95291A (da)	1991-08-16	Rekombinante dna-molekyler
DK677688A (da)	1988-12-05	Humane somatomedinbaererproteinunderenheder og fremgangsmaade til fremstilling af saadanne
IL92257A0 (en)	1990-07-26	Binding proteins for insulin-like growth factors,pharmaceutical compositions containing them and dna fragments encoding them
DE3783191D1 (de)	1993-02-04	Verfahren und mittel zur herstellung eines proteins mit der gleichen igg-spezifizitaet wie protein g.
DE68926888D1 (de)	1996-09-05	Verfahren zur Herstellung von sekretierten Rezeptoranalogen
WO1995021919A3 (en)	1995-12-07	Protein having tpo activity
DE69637148D1 (de)	2007-08-09	Nukleinsäuremoleküle, proteine und peptide, die im zusammenhang stehen mit dickdarmzellen und dickdarm-krebszellen
FI103892B1 (fi)	1999-10-15	Rekombinantti-DNA-molekyyli, joka koodaa polypeptidiä/proteiinia, jolla on oleellisesti vaskulaaristen antikoaguloivien proteiinien biologiset ominaisuudet sekä niiden valmistus
DE3855084D1 (de)	1996-04-18	Herstellung und Reinigung eines Proteins, das mit einem Bindungsprotein fusioniert ist
FI101542B1 (fi)	1998-07-15	Kemiallinen syntetointimenetelmä fibronektiiniä sitovan proteiinin tai polypeptidin valmistamiseksi
PT98806A (pt)	1992-08-31	Processo de preparacao de material genetico codificando novas proteinas de ligacao ao factor de crescimento semelhante a insulina (igfbp-5)
FI921600A0 (fi)	1992-04-10	Bjoerkpollenallergen p14 foer diagnos och behandling av allergiska sjukdomar.
PT98804A (pt)	1992-08-31	Processo de preparacao de igfbp-4 ou um fragmento da mesma
EP0261403A3 (de)	1988-04-13	Polypeptide des Rhinovirusstammes HRV89 sowie die hierfür codierenden DNA-Moleküle
SE8801723D0 (sv)	1988-05-06	Fibronectin binding protein as well as its preparation
WO1995008628A3 (en)	1995-05-11	Nucleic acids encoding merosin, merosin fragments and uses thereof
DK595187D0 (da)	1987-11-13	Minactivin og fremgangsmaade til fremstilling deraf
IL78278A0 (en)	1986-07-31	Process for the production of polypeptides,dna sequence encoding desired polypeptide human somatomedin c polypeptide and recombinant dna molecules
Spencer et al.	1997	Uses for antibodies which bind to human somatomedin carrier protein subunits
MX9504057A (es)	1997-04-30	Proteina que tiene actividad tpo.