DOP2002000386A - ANTIBACTERIAL AGENTS - Google Patents

ANTIBACTERIAL AGENTS

Info

Publication number
DOP2002000386A
DOP2002000386A DO2002000386A DO2002000386A DOP2002000386A DO P2002000386 A DOP2002000386 A DO P2002000386A DO 2002000386 A DO2002000386 A DO 2002000386A DO 2002000386 A DO2002000386 A DO 2002000386A DO P2002000386 A DOP2002000386 A DO P2002000386A
Authority
DO
Dominican Republic
Prior art keywords
formula
antibacterial agents
compounds
useful
preparing compounds
Prior art date
Application number
DO2002000386A
Other languages
Spanish (es)
Inventor
Ellsworth Edmund Lee
Showalter Howard Daniel Hollis
Kim Marie Hutchings
Nguyen Dai Quoc
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of DOP2002000386A publication Critical patent/DOP2002000386A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención proporciona compuestos de la fórmula I: En los que R1-R6 y K tienen cualquiera de los valores definidos en la memoria descriptiva, y sus sales farmacéuticamente aceptables, que son útiles como agentes antibacterianos. También se describen composiciones farmacéuticas que comprenden uno o más compuestos de la fórmula l, procedimientos para preparar compuestos de la fórmula l e intermedios útiles para preparar compuestos de la fórmula l.The present invention provides compounds of the formula I: In which R1-R6 and K have any of the values defined in the specification, and their pharmaceutically acceptable salts, which are useful as antibacterial agents. Pharmaceutical compositions comprising one or more compounds of the formula l, processes for preparing compounds of the formula l and intermediates useful for preparing compounds of the formula l are also described.

DO2002000386A 2001-05-30 2002-04-23 ANTIBACTERIAL AGENTS DOP2002000386A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US29433801P 2001-05-30 2001-05-30

Publications (1)

Publication Number Publication Date
DOP2002000386A true DOP2002000386A (en) 2002-12-15

Family

ID=23132979

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2002000386A DOP2002000386A (en) 2001-05-30 2002-04-23 ANTIBACTERIAL AGENTS

Country Status (4)

Country Link
CA (1) CA2446697A1 (en)
DO (1) DOP2002000386A (en)
PA (1) PA8546201A1 (en)
WO (1) WO2002096908A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200526626A (en) 2003-09-13 2005-08-16 Astrazeneca Ab Chemical compounds
NZ561613A (en) 2005-02-18 2010-12-24 Astrazeneca Ab Antibacterial piperidine derivatives
JP2009520785A (en) * 2005-12-23 2009-05-28 アストラゼネカ アクチボラグ Antibacterial pyrrolopyridine, pyrrolopyrimidine, and pyrroloazepine
US20080139574A1 (en) 2006-11-30 2008-06-12 Cadila Healthcare Limited Novel quinoline derivatives
EA202091945A1 (en) 2018-02-16 2021-01-18 Суновион Фармасьютикалз Инк. SALTS, CRYSTALLINE FORMS AND METHODS OF THEIR PRODUCTION
CN115734785A (en) 2020-04-14 2023-03-03 桑诺维恩药品公司 (S) - (4, 5-dihydro-7H-thieno [2,3-c ] pyran-7-yl) -N-methylmethanamine for the treatment of neurological and psychiatric disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5670506A (en) * 1993-04-05 1997-09-23 Cell Therapeutics, Inc. Halogen, isothiocyanate or azide substituted xanthines
KR960704887A (en) * 1993-10-14 1996-10-09 챨스 엠. 브록 Quininolizinone type compounds

Also Published As

Publication number Publication date
PA8546201A1 (en) 2003-06-30
CA2446697A1 (en) 2002-12-05
WO2002096908A1 (en) 2002-12-05

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