DOP2002000389A - Metodo para fabricar una composición farmaceutica de dosis baja que tiene una distribución y potencia del fármaco uniforme - Google Patents

Metodo para fabricar una composición farmaceutica de dosis baja que tiene una distribución y potencia del fármaco uniforme

Info

Publication number
DOP2002000389A
DOP2002000389A DO2002000389A DO2002000389A DOP2002000389A DO P2002000389 A DOP2002000389 A DO P2002000389A DO 2002000389 A DO2002000389 A DO 2002000389A DO 2002000389 A DO2002000389 A DO 2002000389A DO P2002000389 A DOP2002000389 A DO P2002000389A
Authority
DO
Dominican Republic
Prior art keywords
manufacturing
distribution
power
pharmaceutical composition
low dose
Prior art date
Application number
DO2002000389A
Other languages
English (en)
Inventor
Daniel Scott Gierer
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of DOP2002000389A publication Critical patent/DOP2002000389A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se describe un método para fabricar una compasión farmacéutica que tiene una distribución y potencia del fármaco uniformes, el cual utiliza dióxido de silicio para reducir la pérdida de ingrediente activo durante el proceso de fabricación. El método es particularmente útil para la fabricación de composiciones para comprimidos de baja dosificación.
DO2002000389A 2001-05-01 2002-04-26 Metodo para fabricar una composición farmaceutica de dosis baja que tiene una distribución y potencia del fármaco uniforme DOP2002000389A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28784101P 2001-05-01 2001-05-01

Publications (1)

Publication Number Publication Date
DOP2002000389A true DOP2002000389A (es) 2002-11-30

Family

ID=23104578

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2002000389A DOP2002000389A (es) 2001-05-01 2002-04-26 Metodo para fabricar una composición farmaceutica de dosis baja que tiene una distribución y potencia del fármaco uniforme

Country Status (44)

Country Link
US (2) US7037530B2 (es)
EP (1) EP1383482B1 (es)
JP (1) JP2004531537A (es)
KR (1) KR100568380B1 (es)
CN (1) CN1240375C (es)
AP (1) AP2003002900A0 (es)
AR (1) AR033288A1 (es)
AT (1) ATE367152T1 (es)
AU (1) AU2002236166B2 (es)
BG (1) BG108297A (es)
BR (1) BR0209283A (es)
CA (1) CA2445519C (es)
CZ (1) CZ20032959A3 (es)
DE (1) DE60221238T2 (es)
DK (1) DK1383482T3 (es)
DO (1) DOP2002000389A (es)
EA (1) EA005949B1 (es)
EC (1) ECSP034826A (es)
EE (1) EE200300537A (es)
ES (1) ES2286226T3 (es)
GE (1) GEP20053654B (es)
GT (1) GT200200078A (es)
HR (1) HRP20030858A2 (es)
HU (1) HUP0401391A3 (es)
IL (1) IL158390A0 (es)
IS (1) IS6985A (es)
MA (1) MA27017A1 (es)
MX (1) MXPA03009391A (es)
NO (1) NO20034709L (es)
NZ (1) NZ528886A (es)
OA (1) OA12596A (es)
PA (1) PA8544401A1 (es)
PE (1) PE20021137A1 (es)
PL (1) PL366453A1 (es)
PT (1) PT1383482E (es)
PY (1) PY0206703A (es)
SK (1) SK286536B6 (es)
TN (1) TNSN03106A1 (es)
TW (1) TWI264311B (es)
UA (1) UA75135C2 (es)
UY (1) UY27277A1 (es)
WO (1) WO2002087546A2 (es)
YU (1) YU81503A (es)
ZA (1) ZA200307819B (es)

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CN103830196A (zh) * 2014-03-14 2014-06-04 王志刚 一种酒石酸拉索昔芬分散片及其制备方法
CN106176649B (zh) * 2016-08-31 2020-04-17 北京斯利安药业有限公司 叶酸vb12片及其制备方法
KR102558187B1 (ko) * 2017-02-17 2023-07-24 메사추세츠 인스티튜트 오브 테크놀로지 제약 정제를 비롯한 정제의 제작을 위한 시스템 및 방법
CZ309820B6 (cs) * 2021-04-23 2023-11-08 Pro.Med.Cs Praha A.S. Způsob přípravy pevné lékové formy obsahující kompozici s nízkým obsahem účinné látky
CN117530926A (zh) 2022-08-02 2024-02-09 江苏众红生物工程创药研究院有限公司 一种舌下片及其在脱敏治疗药物中的应用

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Also Published As

Publication number Publication date
AP2003002900A0 (en) 2003-12-31
IL158390A0 (en) 2004-05-12
AR033288A1 (es) 2003-12-10
OA12596A (en) 2006-06-08
KR20040015226A (ko) 2004-02-18
EP1383482B1 (en) 2007-07-18
MXPA03009391A (es) 2004-01-29
US20060093667A1 (en) 2006-05-04
EE200300537A (et) 2004-04-15
AU2002236166B2 (en) 2006-12-07
TWI264311B (en) 2006-10-21
NO20034709L (no) 2003-10-31
HK1065705A1 (en) 2005-03-04
KR100568380B1 (ko) 2006-04-05
PA8544401A1 (es) 2003-07-28
DE60221238D1 (de) 2007-08-30
ES2286226T3 (es) 2007-12-01
HUP0401391A3 (en) 2009-06-29
CA2445519C (en) 2009-01-20
EA200301040A1 (ru) 2004-04-29
ZA200307819B (en) 2004-10-07
IS6985A (is) 2003-10-09
ATE367152T1 (de) 2007-08-15
WO2002087546A3 (en) 2003-02-13
YU81503A (sh) 2006-08-17
US20030004182A1 (en) 2003-01-02
NZ528886A (en) 2005-04-29
MA27017A1 (fr) 2004-12-20
ECSP034826A (es) 2004-02-26
BG108297A (bg) 2005-07-29
CA2445519A1 (en) 2002-11-07
PT1383482E (pt) 2007-09-20
HUP0401391A2 (hu) 2004-12-28
PE20021137A1 (es) 2002-12-14
CZ20032959A3 (cs) 2004-01-14
DE60221238T2 (de) 2007-10-31
GT200200078A (es) 2003-01-31
JP2004531537A (ja) 2004-10-14
UA75135C2 (en) 2006-03-15
DK1383482T3 (da) 2007-10-29
HRP20030858A2 (en) 2005-08-31
UY27277A1 (es) 2002-11-29
BR0209283A (pt) 2004-07-13
CN1240375C (zh) 2006-02-08
EP1383482A2 (en) 2004-01-28
SK13552003A3 (sk) 2004-09-08
US7037530B2 (en) 2006-05-02
EA005949B1 (ru) 2005-08-25
NO20034709D0 (no) 2003-10-21
WO2002087546A2 (en) 2002-11-07
TNSN03106A1 (fr) 2005-12-23
US7176221B2 (en) 2007-02-13
CN1531423A (zh) 2004-09-22
SK286536B6 (sk) 2008-12-05
PY0206703A (es) 2004-07-01
GEP20053654B (en) 2005-11-10
PL366453A1 (pl) 2005-02-07

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