DOP2004000983A - Antagonistas 4-cicloalquilaminopirazol pirimidina de nmda/nr2b - Google Patents
Antagonistas 4-cicloalquilaminopirazol pirimidina de nmda/nr2bInfo
- Publication number
- DOP2004000983A DOP2004000983A DO2004000983A DO2004000983A DOP2004000983A DO P2004000983 A DOP2004000983 A DO P2004000983A DO 2004000983 A DO2004000983 A DO 2004000983A DO 2004000983 A DO2004000983 A DO 2004000983A DO P2004000983 A DOP2004000983 A DO P2004000983A
- Authority
- DO
- Dominican Republic
- Prior art keywords
- nmda
- nr2b
- cyclalkylaminopirazol
- antigonists
- pyrimidine
- Prior art date
Links
- HOKKHZGPKSLGJE-GSVOUGTGSA-N N-Methyl-D-aspartic acid Chemical compound CN[C@@H](C(O)=O)CC(O)=O HOKKHZGPKSLGJE-GSVOUGTGSA-N 0.000 title abstract 2
- 102000034527 Retinoid X Receptors Human genes 0.000 title abstract 2
- 108010038912 Retinoid X Receptors Proteins 0.000 title abstract 2
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 title 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 208000029028 brain injury Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 230000000302 ischemic effect Effects 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Compounds represented by Formula (I): (where R1 and Y are defined herein) or pharmaceutically acceptable salts thereof, are effective as NMDA/NR2B antagonists useful for treating neurological conditions such as, for example, pain, Parkinson's disease, Alzheimer's disease, epilepsy, depression, anxiety, ischemic brain injury including stroke, and other conditions.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DO2004000983A DOP2004000983A (es) | 2004-08-23 | 2004-08-23 | Antagonistas 4-cicloalquilaminopirazol pirimidina de nmda/nr2b |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DO2004000983A DOP2004000983A (es) | 2004-08-23 | 2004-08-23 | Antagonistas 4-cicloalquilaminopirazol pirimidina de nmda/nr2b |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DOP2004000983A true DOP2004000983A (es) | 2006-03-28 |
Family
ID=44261399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DO2004000983A DOP2004000983A (es) | 2004-08-23 | 2004-08-23 | Antagonistas 4-cicloalquilaminopirazol pirimidina de nmda/nr2b |
Country Status (1)
| Country | Link |
|---|---|
| DO (1) | DOP2004000983A (es) |
-
2004
- 2004-08-23 DO DO2004000983A patent/DOP2004000983A/es unknown
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