DZ2254A1 - Analogues d'indazole nouveaux. - Google Patents

Analogues d'indazole nouveaux.

Info

Publication number
DZ2254A1
DZ2254A1 DZ970104A DZ970104A DZ2254A1 DZ 2254 A1 DZ2254 A1 DZ 2254A1 DZ 970104 A DZ970104 A DZ 970104A DZ 970104 A DZ970104 A DZ 970104A DZ 2254 A1 DZ2254 A1 DZ 2254A1
Authority
DZ
Algeria
Prior art keywords
indazole analogues
new indazole
new
analogues
indazole
Prior art date
Application number
DZ970104A
Other languages
English (en)
Inventor
Anthony Marfat
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DZ2254A1 publication Critical patent/DZ2254A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DZ970104A 1996-06-25 1997-06-24 Analogues d'indazole nouveaux. DZ2254A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2038596P 1996-06-25 1996-06-25

Publications (1)

Publication Number Publication Date
DZ2254A1 true DZ2254A1 (fr) 2002-12-18

Family

ID=21798354

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ970104A DZ2254A1 (fr) 1996-06-25 1997-06-24 Analogues d'indazole nouveaux.

Country Status (42)

Country Link
US (1) US6040329A (fr)
EP (1) EP0912558B1 (fr)
JP (1) JP3152940B2 (fr)
KR (1) KR20000022516A (fr)
CN (1) CN1080260C (fr)
AP (1) AP1025A (fr)
AR (1) AR007456A1 (fr)
AT (1) ATE244713T1 (fr)
AU (1) AU716376B2 (fr)
BG (1) BG64052B1 (fr)
BR (1) BR9712782A (fr)
CA (1) CA2258285C (fr)
CO (1) CO4900056A1 (fr)
CZ (1) CZ423398A3 (fr)
DE (1) DE69723447T2 (fr)
DK (1) DK0912558T3 (fr)
DZ (1) DZ2254A1 (fr)
EA (1) EA002274B1 (fr)
ES (1) ES2201299T3 (fr)
GT (1) GT199700075A (fr)
HN (1) HN1997000079A (fr)
HR (1) HRP970350B1 (fr)
HU (1) HUP9903009A3 (fr)
ID (1) ID18579A (fr)
IL (1) IL127036A (fr)
IS (1) IS4910A (fr)
MA (1) MA24225A1 (fr)
MY (1) MY116915A (fr)
NO (1) NO986103L (fr)
NZ (1) NZ332752A (fr)
OA (1) OA10934A (fr)
PA (1) PA8432301A1 (fr)
PL (1) PL330974A1 (fr)
PT (1) PT912558E (fr)
SI (1) SI0912558T1 (fr)
SK (1) SK176598A3 (fr)
TN (1) TNSN97108A1 (fr)
TR (1) TR199802685T2 (fr)
TW (1) TW434237B (fr)
WO (1) WO1997049702A1 (fr)
YU (1) YU60198A (fr)
ZA (1) ZA975581B (fr)

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JP4373497B2 (ja) 1996-06-19 2009-11-25 ローン−プーラン・ロレ・リミテツド 置換されたアザビシクロ化合物、ならびにｔｎｆおよびサイクリックａｍｐホスホジエステラーゼ産生の阻害剤としてのそれらの使用
EA002113B1 (ru) * 1996-09-04 2001-12-24 Пфайзер Инк. Производные индазола и их использование в качестве ингибиторов фосфодиэстеразы (фдэ) типа iv и продуцирования фактора некроза опухоли (фно)
US6248746B1 (en) 1998-01-07 2001-06-19 Euro-Celtique S.A. 3-(arylalkyl) xanthines
IL135714A0 (en) * 1997-11-04 2001-05-20 Pfizer Prod Inc Therapeutically active compounds based on indazole bioisostere replacement of catechol in pde4 inhibitors
IL135900A0 (en) * 1997-11-04 2001-05-20 Pfizer Prod Inc Indazole bioisostere replacement of catechol in therapeuticaly active compounds
US6362213B1 (en) 1999-12-23 2002-03-26 Icos Corporation Cyclic AMP-specific phosphodiesterase inhibitors
PT1244649E (pt) * 1999-12-23 2005-06-30 Icos Corp Inibidores de fosfodiesterase especificos de mfa ciclica
US6953774B2 (en) 2000-08-11 2005-10-11 Applied Research Systems Ars Holding N.V. Methods of inducing ovulation
US7153871B2 (en) 2001-01-22 2006-12-26 Memory Pharmaceuticals Corporation Phosphodiesterase 4 inhibitors, including aminoindazole and aminobenzofuran analogs
US7205320B2 (en) 2001-01-22 2007-04-17 Memory Pharmaceuticals Corp. Phosphodiesterase 4 inhibitors
CN1300116C (zh) * 2001-04-16 2007-02-14 卫材株式会社 1h－吲唑化合物
US7507707B2 (en) 2001-12-14 2009-03-24 Laboratoires Serono Sa Methods of inducing ovulation using a non-polypeptide camp level modulator
AU2003256616B2 (en) 2002-07-19 2009-08-27 Memory Pharmaceuticals Corporation Phosphodiesterase 4 inhibitors, including N-substituted aniline and diphenylamine analogs
DE60325984D1 (de) * 2002-07-19 2009-03-12 Memory Pharmaceutical Corp 4-aminobenzofuranverbindungen als phosphodiesterase-4-inhibitoren
CA2506297A1 (fr) 2002-11-19 2004-06-03 Memory Pharmaceuticals Corporation Inhibiteurs de la phosphodiesterase 4
EP1631568A1 (fr) * 2003-04-18 2006-03-08 Memory Pharmaceuticals Corporation Derives du pyrazole inhibiteurs de la phosphodiesterase 4
US20090048255A1 (en) * 2003-07-21 2009-02-19 Schumacher Richard A Phosphodiesterase 4 inhibitors, including n-substituted aniline and diphenylamine analogs
MY141255A (en) * 2003-12-11 2010-03-31 Memory Pharm Corp Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs
EP1799673A1 (fr) 2004-10-15 2007-06-27 Memory Pharmaceuticals Corporation Derives de pyrazole utilises en tant qu'inhibiteurs de phosphodiesterase 4
US7601847B2 (en) 2004-10-26 2009-10-13 Wyeth Preparation and purification of 4-(indazol-3-yl)phenols
EP1891060A2 (fr) * 2005-05-30 2008-02-27 Ranbaxy Laboratories Limited Derives de 3-indazolyl-isoxazoline en tant qu'inhibiteurs de la phosphodiesterase de type iv
EP2258358A3 (fr) 2005-08-26 2011-09-07 Braincells, Inc. Neurogenèse avec un inhibiteur de l'acetylcholinestérase
EP2275095A3 (fr) 2005-08-26 2011-08-17 Braincells, Inc. Neurogenese par modulation des recepteurs muscariniques
US7781460B2 (en) 2005-09-05 2010-08-24 Ranbaxy Laboratories Limited Substituted indazoles as inhibitors of phosphodiesterase type-IV
WO2007031838A1 (fr) 2005-09-16 2007-03-22 Ranbaxy Laboratories Limited Pyrazolo[3,4-b]pyridines substituees en tant qu'inhibiteurs de la phosphodiesterase
EP1940389A2 (fr) 2005-10-21 2008-07-09 Braincells, Inc. Modulation de la neurogenese par inhibition de la pde
AU2006308889A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. GABA receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2382975A3 (fr) 2006-05-09 2012-02-29 Braincells, Inc. Neurogénèse par modulation d'angiotensine
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
NZ579645A (en) 2007-03-14 2012-01-12 Ranbaxy Lab Ltd Pyrazolo (3, 4-b) pyridine derivatives as phosphodiesterase inhibitors
US20100029689A1 (en) * 2008-07-02 2010-02-04 Memory Pharmaceuticals Corporation Phosphodiesterase 4 inhibitors
WO2010099217A1 (fr) 2009-02-25 2010-09-02 Braincells, Inc. Modulation de neurogenèse à l'aide de combinaisons de d-cyclosérine
KR101774035B1 (ko) * 2009-10-30 2017-09-01 얀센 파마슈티카 엔.브이. 이미다조［１，２―ｂ］피리다진 유도체 및 ＰＤＥ１０ 저해제로서의 그의 용도
WO2013106547A1 (fr) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Composés promoteurs de réplication des cellules bêta et leurs procédés d'utilisation
US20150125438A1 (en) * 2012-07-20 2015-05-07 Sang Jae Kim Anti-Inflammatory Peptides and Composition Comprising the Same
EP3137454A1 (fr) 2014-04-28 2017-03-08 Pfizer Inc. Composés hétéroaromatiques et leur utilisation en tant que ligands de la dopamine d1
KR20220167804A (ko) * 2021-06-11 2022-12-22 주식회사 메타센테라퓨틱스 인돌 유도체를 포함하는 최종당화산물 관련 질환의 치료용 조성물
KR20220167441A (ko) * 2021-06-11 2022-12-21 주식회사 메타센테라퓨틱스 신규한 인돌 유도체 및 이의 최종당화산물 관련 질환의 치료 용도

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Also Published As

Publication number Publication date
IL127036A0 (en) 1999-09-22
AU2785797A (en) 1998-01-14
NZ332752A (en) 2001-04-27
MY116915A (en) 2004-04-30
BR9712782A (pt) 1999-12-07
OA10934A (en) 2002-02-18
GT199700075A (es) 1998-12-04
HN1997000079A (es) 1997-12-26
PL330974A1 (en) 1999-06-21
HRP970350A2 (en) 1998-06-30
IS4910A (is) 1998-11-27
TNSN97108A1 (fr) 2005-03-15
SI0912558T1 (en) 2003-10-31
CN1223651A (zh) 1999-07-21
CN1080260C (zh) 2002-03-06
AU716376B2 (en) 2000-02-24
HUP9903009A3 (en) 2002-01-28
TW434237B (en) 2001-05-16
BG103056A (en) 1999-10-29
DE69723447T2 (de) 2003-12-24
IL127036A (en) 2001-06-14
CZ423398A3 (cs) 1999-12-15
JPH11514668A (ja) 1999-12-14
DE69723447D1 (de) 2003-08-14
EP0912558B1 (fr) 2003-07-09
NO986103D0 (no) 1998-12-23
EA199801047A1 (ru) 1999-06-24
CO4900056A1 (es) 2000-03-27
ES2201299T3 (es) 2004-03-16
AP9701020A0 (en) 1997-07-31
SK176598A3 (en) 2000-06-12
PA8432301A1 (es) 1999-12-27
WO1997049702A1 (fr) 1997-12-31
YU60198A (sh) 1999-09-27
KR20000022516A (ko) 2000-04-25
PT912558E (pt) 2003-11-28
DK0912558T3 (da) 2003-08-18
EA002274B1 (ru) 2002-02-28
HRP970350B1 (en) 2003-04-30
HK1018700A1 (en) 1999-12-30
ID18579A (id) 1998-04-23
NO986103L (no) 1998-12-23
ZA975581B (en) 1998-12-24
AR007456A1 (es) 1999-10-27
CA2258285C (fr) 2002-11-26
TR199802685T2 (xx) 1999-03-22
ATE244713T1 (de) 2003-07-15
JP3152940B2 (ja) 2001-04-03
HUP9903009A2 (hu) 2000-05-28
EP0912558A1 (fr) 1999-05-06
US6040329A (en) 2000-03-21
AP1025A (en) 2001-11-19
MA24225A1 (fr) 1997-12-31
CA2258285A1 (fr) 1997-12-31
BG64052B1 (bg) 2003-11-28

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