DZ2316A1 - Micro sphères pharmaceutiques d'acide valproique pour administration orale. - Google Patents

Micro sphères pharmaceutiques d'acide valproique pour administration orale.

Info

Publication number: DZ2316A1
Authority: DZ; Algeria
Prior art keywords: oral administration; valproic acid; micro spheres; pharmaceutical micro; pharmaceutical
Prior art date: 1996-10-07

Application number

DZ970166A

Other languages

English (en)

French (fr)

Inventor

Christian Langlois

Jean-Yves Lanne

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-10-07

Filing date

1997-09-24

Publication date

2002-12-28

1997-09-24 Application filed by Sanofi Sa filed Critical Sanofi Sa

2002-12-28 Application granted granted Critical

2002-12-28 Publication of DZ2316A1 publication Critical patent/DZ2316A1/xx

Links

NIJJYAXOARWZEE-UHFFFAOYSA-N Valproic acid Chemical compound CCCC(C(O)=O)CCC NIJJYAXOARWZEE-UHFFFAOYSA-N 0.000 title 2
239000004005 microsphere Substances 0.000 title 1
229960000604 valproic acid Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Neurosurgery (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DZ970166A 1996-10-07 1997-09-24 Micro sphères pharmaceutiques d'acide valproique pour administration orale. DZ2316A1 (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9612201A FR2754177B1 (fr)	1996-10-07	1996-10-07	Microspheres pharmaceutiques d'acide valproique pour administration orale

Publications (1)

Publication Number	Publication Date
DZ2316A1 true DZ2316A1 (fr)	2002-12-28

Family

ID=9496427

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ970166A DZ2316A1 (fr)	1996-10-07	1997-09-24	Micro sphères pharmaceutiques d'acide valproique pour administration orale.

Country Status (39)

Country	Link
US (3)	US20020001598A1 (de)
EP (1)	EP0956010B1 (de)
JP (1)	JP3523270B2 (de)
KR (1)	KR100334687B1 (de)
CN (1)	CN100367945C (de)
AR (1)	AR013613A1 (de)
AT (1)	ATE216228T1 (de)
AU (1)	AU731235B2 (de)
BR (1)	BR9712268A (de)
CA (1)	CA2267096C (de)
CO (1)	CO4900080A1 (de)
CZ (1)	CZ288876B6 (de)
DE (1)	DE69712100T2 (de)
DK (1)	DK0956010T3 (de)
DZ (1)	DZ2316A1 (de)
EE (1)	EE03744B1 (de)
EG (1)	EG24070A (de)
ES (1)	ES2174293T3 (de)
FR (1)	FR2754177B1 (de)
HR (1)	HRP970537B1 (de)
HU (1)	HU225103B1 (de)
ID (1)	ID24596A (de)
IL (1)	IL128745A (de)
IS (1)	IS1985B (de)
ME (1)	ME00664B (de)
MY (1)	MY120521A (de)
NO (1)	NO325723B1 (de)
NZ (1)	NZ334399A (de)
PL (1)	PL190105B1 (de)
PT (1)	PT956010E (de)
RS (1)	RS49602B (de)
RU (1)	RU2177315C2 (de)
SI (1)	SI0956010T1 (de)
SK (1)	SK282113B6 (de)
TR (1)	TR199900789T2 (de)
TW (1)	TW508251B (de)
UY (1)	UY24738A1 (de)
WO (1)	WO1998015268A1 (de)
ZA (1)	ZA978954B (de)

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EE200100660A (et) *	1999-06-07	2003-04-15	Byk Gulden Lomberg Chemische Fabrik Gmbh	Ravimvorm happe suhtes labiilsete toimeainete jaoks, toimeaine üksus, selle valmistamismeetod ja mikrokerake
AU2003289782A1 (en) *	2002-12-16	2004-07-09	The University Of British Columbia	Valproic acid analogues and pharmaceutical compositions thereof
TWI547431B (zh) *	2004-06-09	2016-09-01	史密斯克萊美占公司	生產藥物之裝置及方法
BRPI0515645A (pt) *	2004-09-07	2008-03-04	Orphan Medical Inc	métodos terapêuticos, composições, compostos e usos de compostos
US9149433B2 (en) *	2004-11-30	2015-10-06	Basf Corporation	Method for formation of micro-prilled polymers
US20060252830A1 (en) *	2005-05-06	2006-11-09	Brandon Stephen F	Method for the treatment of magnesium and potassium deficiencies
US20060252831A1 (en) *	2005-05-06	2006-11-09	Christopher Offen	Method for the treatment of magnesium and potassium deficiencies
US8992422B2 (en)	2006-03-23	2015-03-31	Ethicon Endo-Surgery, Inc.	Robotically-controlled endoscopic accessory channel
CN101543631B (zh) *	2008-03-28	2012-01-11	沈阳兴齐制药有限公司	含蜂蜡的微球基质、含有它的药物组合物及其用途
EP2431031B1 (de) *	2009-05-12	2016-06-08	Amorepacific Corporation	Zusammensetzung zur verhinderung von haarverlust und zur stimulation des haarwachstums
AU2014350208B2 (en) *	2013-11-13	2017-09-07	Tillotts Pharma Ag	Multi-particulate drug delivery system
CN104013596A (zh) *	2014-05-16	2014-09-03	安士制药（中山）有限公司	一种丙戊酸软胶囊及其制备方法
CN105456217A (zh) *	2014-08-27	2016-04-06	捷思英达医药技术（上海）有限公司	一种双丙戊酸钠缓释剂组合物及其制备方法
WO2019039345A1 (ja)	2017-08-24	2019-02-28	三井化学株式会社	リチウム二次電池及び非水電解液
US11652237B2 (en)	2017-08-24	2023-05-16	Mitsui Chemicals, Inc.	Nonaqueous electrolyte solution including boron compound additive having higher reductive decomposition potential than additional additive and lithium secondary battery including the same
FR3087445B1 (fr) *	2018-10-19	2021-12-17	Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic	Composition lipidique pour l'encapsulation d'une substance active et permettant le controle de la vitesse de liberation de ladite substance active
CN111012753A (zh) *	2020-01-07	2020-04-17	仁和堂药业有限公司	一种提高丙戊酸钠片剂稳定性的方法
CN112274499A (zh) *	2020-11-16	2021-01-29	仁和堂药业有限公司	一种提高丙戊酸钠片剂稳定性的方法

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FR2293974A1 (fr) *	1973-03-02	1976-07-09	Kaltenbach Roger	Procede et dispositif pour la granulation reguliere de divers produits
US5212326A (en) *	1979-08-20	1993-05-18	Abbott Laboratories	Sodium hydrogen divalproate oligomer
DK150008C (da) *	1981-11-20	1987-05-25	Benzon As Alfred	Fremgangsmaade til fremstilling af et farmaceutisk oralt polydepotpraeparat
IL72381A (en) *	1983-07-20	1988-03-31	Sanofi Sa	Pharmaceutical composition based on valproic acid
US5185159A (en) *	1983-07-20	1993-02-09	Sanofi	Pharmaceutical composition based on valproic acid and a process for preparing it
US4913906B1 (en) *	1985-02-28	2000-06-06	Yissum Res Dev Co	Controlled release dosage form of valproic acid
JP2893191B2 (ja) *	1988-11-08	1999-05-17	武田薬品工業株式会社	放出制御性マトリックス剤
EP0418596A3 (en) *	1989-09-21	1991-10-23	American Cyanamid Company	Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form
FR2657257B1 (fr) *	1990-01-19	1994-09-02	Rhone Poulenc Sante	Procede de preparation de medicaments sous forme de perles.
TW209174B (de) *	1991-04-19	1993-07-11	Takeda Pharm Industry Co Ltd
WO1992020326A1 (en) *	1991-05-20	1992-11-26	Marion Laboratories, Inc.	Multi-layered controlled release formulation
FR2682677A1 (fr) *	1991-10-17	1993-04-23	Sanofi Elf	Complexe forme de l'acide propyl-2 pentene-2 ouique (e) et de son sel de sodium, sa preparation et compositions pharmaceutiques le contenant.
US6287598B1 (en) *	1993-05-28	2001-09-11	Alza Corporation	Method for providing sustained antiepileptic therapy
US5690959A (en) *	1993-05-29	1997-11-25	Smithkline Beecham Corporation	Pharmaceutical thermal infusion process
AUPN969796A0 (en) *	1996-05-07	1996-05-30	F.H. Faulding & Co. Limited	Taste masked liquid suspensions
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US6248363B1 (en) *	1999-11-23	2001-06-19	Lipocine, Inc.	Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
UA80393C2 (uk) *	2000-12-07	2007-09-25	Алтана Фарма Аг	Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці

1996
- 1996-10-07 FR FR9612201A patent/FR2754177B1/fr not_active Expired - Fee Related
1997
- 1997-09-24 DZ DZ970166A patent/DZ2316A1/xx active
- 1997-10-03 ES ES97943943T patent/ES2174293T3/es not_active Expired - Lifetime
- 1997-10-03 NZ NZ334399A patent/NZ334399A/xx not_active IP Right Cessation
- 1997-10-03 CZ CZ19991211A patent/CZ288876B6/cs not_active IP Right Cessation
- 1997-10-03 RU RU99109087/14A patent/RU2177315C2/ru active
- 1997-10-03 DE DE69712100T patent/DE69712100T2/de not_active Expired - Lifetime
- 1997-10-03 SI SI9730352T patent/SI0956010T1/xx unknown
- 1997-10-03 IL IL12874597A patent/IL128745A/en not_active IP Right Cessation
- 1997-10-03 ME MEP-1999-178A patent/ME00664B/me unknown
- 1997-10-03 SK SK364-99A patent/SK282113B6/sk not_active IP Right Cessation
- 1997-10-03 AT AT97943943T patent/ATE216228T1/de active
- 1997-10-03 HU HU9903855A patent/HU225103B1/hu unknown
- 1997-10-03 CO CO97057983A patent/CO4900080A1/es unknown
- 1997-10-03 EE EEP199900140A patent/EE03744B1/xx unknown
- 1997-10-03 US US09/147,788 patent/US20020001598A1/en not_active Abandoned
- 1997-10-03 BR BR9712268-8A patent/BR9712268A/pt not_active IP Right Cessation
- 1997-10-03 PT PT97943943T patent/PT956010E/pt unknown
- 1997-10-03 CA CA002267096A patent/CA2267096C/fr not_active Expired - Lifetime
- 1997-10-03 KR KR1019997002824A patent/KR100334687B1/ko not_active Expired - Lifetime
- 1997-10-03 CN CNB971985375A patent/CN100367945C/zh not_active Expired - Lifetime
- 1997-10-03 EP EP97943943A patent/EP0956010B1/de not_active Expired - Lifetime
- 1997-10-03 JP JP51724598A patent/JP3523270B2/ja not_active Expired - Lifetime
- 1997-10-03 AU AU45602/97A patent/AU731235B2/en not_active Expired
- 1997-10-03 WO PCT/FR1997/001762 patent/WO1998015268A1/fr not_active Ceased
- 1997-10-03 PL PL97332249A patent/PL190105B1/pl unknown
- 1997-10-03 TR TR1999/00789T patent/TR199900789T2/xx unknown
- 1997-10-03 DK DK97943943T patent/DK0956010T3/da active
- 1997-10-03 ID IDW990095D patent/ID24596A/id unknown
- 1997-10-03 RS YUP-178/99A patent/RS49602B/sr unknown
- 1997-10-06 AR ARP970104595A patent/AR013613A1/es active IP Right Grant
- 1997-10-06 UY UY24738A patent/UY24738A1/es not_active Application Discontinuation
- 1997-10-07 ZA ZA978954A patent/ZA978954B/xx unknown
- 1997-10-07 EG EG103597A patent/EG24070A/xx active
- 1997-10-07 MY MYPI97004682A patent/MY120521A/en unknown
- 1997-10-07 HR HR970537A patent/HRP970537B1/xx not_active IP Right Cessation
- 1997-11-25 TW TW086117675A patent/TW508251B/zh active
1999
- 1999-03-11 IS IS4996A patent/IS1985B/is unknown
- 1999-04-06 NO NO19991613A patent/NO325723B1/no not_active IP Right Cessation
2002
- 2002-10-15 US US10/270,159 patent/US20030157177A1/en not_active Abandoned
2006
- 2006-02-21 US US11/357,426 patent/US8535721B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2267096C (fr)	2003-09-16
SK282113B6 (sk)	2001-11-06
UY24738A1 (es)	2001-05-31
SI0956010T1 (en)	2002-10-31
NZ334399A (en)	2000-05-26
HUP9903855A3 (en)	2000-06-28
HRP970537A2 (en)	1998-08-31
NO991613L (no)	1999-04-06
FR2754177B1 (fr)	1999-08-06
PL190105B1 (pl)	2005-10-31
AU4560297A (en)	1998-05-05
ATE216228T1 (de)	2002-05-15
NO991613D0 (no)	1999-04-06
EE03744B1 (et)	2002-06-17
CZ121199A3 (cs)	1999-08-11
JP2000504038A (ja)	2000-04-04
KR100334687B1 (ko)	2002-04-27
AR013613A1 (es)	2001-01-10
IS1985B (is)	2005-02-15
ZA978954B (en)	1999-04-07
EP0956010A1 (de)	1999-11-17
HUP9903855A2 (hu)	2000-05-28
MY120521A (en)	2005-11-30
TR199900789T2 (xx)	1999-07-21
DK0956010T3 (da)	2002-08-12
CZ288876B6 (cs)	2001-09-12
IL128745A0 (en)	2000-01-31
HU225103B1 (en)	2006-06-28
US20020001598A1 (en)	2002-01-03
SK36499A3 (en)	2000-12-11
IS4996A (is)	1999-03-11
CN1232391A (zh)	1999-10-20
TW508251B (en)	2002-11-01
ME00664B (me)	2007-06-04
CN100367945C (zh)	2008-02-13
DE69712100T2 (de)	2002-11-28
JP3523270B2 (ja)	2004-04-26
RU2177315C2 (ru)	2001-12-27
HRP970537B1 (en)	2002-08-31
FR2754177A1 (fr)	1998-04-10
CA2267096A1 (fr)	1998-04-16
DE69712100D1 (de)	2002-05-23
WO1998015268A1 (fr)	1998-04-16
US8535721B2 (en)	2013-09-17
ID24596A (id)	2000-07-27
IL128745A (en)	2004-05-12
BR9712268A (pt)	1999-08-31
ES2174293T3 (es)	2002-11-01
US20060263437A1 (en)	2006-11-23
NO325723B1 (no)	2008-07-07
YU17899A (sh)	2000-03-21
CO4900080A1 (es)	2000-03-27
EP0956010B1 (de)	2002-04-17
AU731235B2 (en)	2001-03-29
KR20000048828A (ko)	2000-07-25
RS49602B (sr)	2007-06-04
EG24070A (en)	2008-05-11
PT956010E (pt)	2002-08-30
PL332249A1 (en)	1999-08-30
US20030157177A1 (en)	2003-08-21
EE9900140A (et)	1999-12-15
HK1021939A1 (zh)	2000-07-21

Publication	Publication Date	Title
FR2754177B1 (fr)	1999-08-06	Microspheres pharmaceutiques d'acide valproique pour administration orale
FR2761266B1 (fr)	1999-07-02	Composition pharmaceutique formee par granulation humide pour l'administration orale d'un derive du n-piperidino-3- pyrazolecarboxamide, de ses sels et de leurs solvates
FI950947L (fi)	1995-09-03	Oraalisesti annettavat farmaseuttiset formulaatiot
MA26456A1 (fr)	2004-12-20	Formulations pharmaceutiques pour la distribution prolongee de medicament.
DZ1876A1 (fr)	2002-02-17	Médicaments pour administration orale.
FR2734483B1 (fr)	1997-07-11	Forme d'administration pharmaceutique comprenant de l'oxybutynine
EP1028710A4 (de)	2006-03-15	Topische mittel zur verabreichung nichtsteroidaler antiinflammatorischer wirkstoffe
MA26471A1 (fr)	2004-12-20	Derives d'acide arylsulfonylaminohydroxamique, procede pour leur preparation et compositions pharmaceutiques les contenant.
DZ1078A1 (fr)	2004-09-13	Formulation pharmaceutiques de substance labiles aux acides pour administration orale.
MA26571A1 (fr)	2004-12-20	Derives d'acide hydroxamique, compositions pharmaceutiques les contenant et procede pour leur preparation
FR2688405B1 (fr)	1995-03-03	Procede d'une preparation d'une solution medicinale stable pour voie orale a liberation controlee, a base d'un beta-bloquant, et composition pharmaceutique a base d'un beta-bloquant.
EP0652770A4 (de)	1996-05-29	Orale gabe von antigenen.
EP0601058A4 (de)	1995-05-31	Transdermale formulierungen zur prazosinverabreichung.
ITMI941262A0 (it)	1994-06-17	Composizione farmaceutica solida contenente acido (s)-2-(4- isobutilfenil) propionico come principio attivo
NO950134D0 (no)	1995-01-13	Formuleringer for oralt administrerte farmasöytiske midler
NL193820B (nl)	2000-08-01	Vaste farmaceutische doseringsvorm voor orale toediening van Ibuprofen.
MA24183A1 (fr)	1997-12-31	Procede pour la preparation de compositions pharmaceutiques a base de diclofenac
MA23663A1 (fr)	1996-04-01	Procede de preparation de formulations pharmaceutiques
FR2678836B1 (fr)	1995-06-09	Formulations pour voie orale d'ubidecarenone sous la forme de solutions aqueuses.
NO951933D0 (no)	1995-05-16	Farmasöytiske formuleringer av ibuprofen
FR2685204B1 (fr)	1995-06-16	Compositions pharmaceutiques pour l'administration transcutanee de la fenfluramine.
FR2702960B1 (fr)	1995-06-16	Leurre pour l'administration orale de médicaments vétérinaires.
FR2602680B1 (fr)	1993-04-16	Compositions pharmaceutiques pour l'administration par voie nasale
FR2541114B1 (fr)	1986-04-11	Compositions pharmaceutiques antifongiques utilisables par voie orale contenant de l'omoconazole
KR970000226A (ko)	1997-01-21	S-이부프로펜의 경구용 제형