DZ2609A1 - Composés nouveaux antagonistes des récepteurs de vitronectine et compositions pharmaceutiques les contenant. - Google Patents

Composés nouveaux antagonistes des récepteurs de vitronectine et compositions pharmaceutiques les contenant.

Info

Publication number: DZ2609A1
Authority: DZ; Algeria
Prior art keywords: pharmaceutical compositions; compositions containing; receptor antagonists; new compounds; vitronectin receptor
Prior art date: 1997-09-19

Application number

DZ980219A

Other languages

English (en)

French (fr)

Inventor

William E Bondinell

William H Miller

Heerding Dirk

James M Samanen

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-19

Filing date

1998-09-16

Publication date

2003-03-01

1998-09-16 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

2003-03-01 Application granted granted Critical

2003-03-01 Publication of DZ2609A1 publication Critical patent/DZ2609A1/xx

Links

102100022337 Integrin alpha-V Human genes 0.000 title 1
108010048673 Vitronectin Receptors Proteins 0.000 title 1
150000001875 compounds Chemical class 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
239000002464 receptor antagonist Substances 0.000 title 1
229940044551 receptor antagonist Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/44—Nitrogen atoms not forming part of a nitro radical
- C07D233/48—Nitrogen atoms not forming part of a nitro radical with acyclic hydrocarbon or substituted acyclic hydrocarbon radicals, attached to said nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D239/08—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
- C07D239/12—Nitrogen atoms not forming part of a nitro radical
- C07D239/14—Nitrogen atoms not forming part of a nitro radical with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to said nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/14—[b,f]-condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Orthopedic Medicine & Surgery (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pain & Pain Management (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Thiazole And Isothizaole Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

DZ980219A 1997-09-19 1998-09-16 Composés nouveaux antagonistes des récepteurs de vitronectine et compositions pharmaceutiques les contenant. DZ2609A1 (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US5934297P	1997-09-19	1997-09-19
US6343897P	1997-10-29	1997-10-29

Publications (1)

Publication Number	Publication Date
DZ2609A1 true DZ2609A1 (fr)	2003-03-01

Family

ID=26738652

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DZ980219A DZ2609A1 (fr)	1997-09-19	1998-09-16	Composés nouveaux antagonistes des récepteurs de vitronectine et compositions pharmaceutiques les contenant.

Country Status (26)

Country	Link
EP (1)	EP1025090A4 (id)
JP (1)	JP2001517658A (id)
KR (1)	KR20010024141A (id)
CN (1)	CN1278250A (id)
AP (1)	AP2000001766A0 (id)
AR (1)	AR015446A1 (id)
AU (1)	AU738433B2 (id)
BG (1)	BG104314A (id)
BR (1)	BR9812340A (id)
CA (1)	CA2303487A1 (id)
CO (1)	CO5011087A1 (id)
DZ (1)	DZ2609A1 (id)
EA (1)	EA200000336A1 (id)
HU (1)	HUP0003641A3 (id)
ID (1)	ID24162A (id)
IL (1)	IL135028A0 (id)
MA (1)	MA26547A1 (id)
NO (1)	NO20001407L (id)
NZ (1)	NZ503389A (id)
OA (1)	OA11341A (id)
PE (1)	PE122699A1 (id)
PL (1)	PL339381A1 (id)
SK (1)	SK4082000A3 (id)
TR (1)	TR200000721T2 (id)
TW (1)	TW513303B (id)
WO (1)	WO1999015508A1 (id)

Families Citing this family (18)

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CO4920232A1 (es) *	1997-01-08	2000-05-29	Smithkline Beecham Corp	Acidos aceticos dibenzo [a,d] cicloheptano con actividad antagonista del receptor de vitronectin
CA2358855A1 (en)	1999-02-03	2000-08-10	Merck & Co., Inc.	Benzazepine derivatives as alpha-v integrin receptor antagonists
DE19936780A1 (de) *	1999-08-09	2001-02-15	Basf Ag	Neue Antagonisten von Integrinrezeptoren
US6881736B1 (en)	1999-09-07	2005-04-19	Smithkline Beecham Corporation	Vitronectin receptor antagonists
EG24179A (en) *	1999-09-07	2008-09-28	Smithkline Beecham Corp	Vitronectin receptor antagonists
US6514964B1 (en)	1999-09-27	2003-02-04	Amgen Inc.	Fused cycloheptane and fused azacycloheptane compounds and their methods of use
FR2806082B1 (fr) *	2000-03-07	2002-05-17	Adir	Nouveaux composes bicycliques antagonistes des recepteurs de la vitronectine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
AU2001268490A1 (en) *	2000-06-15	2001-12-24	Pharmacia Corporation	Dihydrostilbene alkanoic acid derivatives useful as vitronectin antagonists
JP2004513953A (ja) *	2000-10-24	2004-05-13	メルク　エンド　カムパニー　インコーポレーテッド	ジベンズオキサゼピンαＶインテグリン受容体アンタゴニスト
WO2002085405A2 (en)	2001-04-24	2002-10-31	Merck Patent Gmbh	COMBINATION THERAPY USING ANTI-ANGIOGENIC AGENTS AND TNF$g(a)
GB0215867D0 (en) *	2002-07-09	2002-08-14	Glaxosmithkline Spa	Novel method and compounds
US20040224986A1 (en)	2002-08-16	2004-11-11	Bart De Corte	Piperidinyl targeting compounds that selectively bind integrins
UA87854C2 (en)	2004-06-07	2009-08-25	Мерк Энд Ко., Инк.	N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
AU2007207465B2 (en)	2006-01-18	2012-12-06	Merck Patent Gmbh	Specific therapy using integrin ligands for treating cancer
CN101588812A (zh)	2007-01-18	2009-11-25	默克专利有限公司	使用整联蛋白配体治疗癌的特异疗法和药物
NZ597339A (en)	2009-05-25	2013-10-25	Merck Patent Gmbh	Continuous administration of cilengitide in cancer treatments
SG11201609050UA (en)	2014-05-30	2016-12-29	Pfizer	Carbonitrile derivatives as selective androgen receptor modulators
WO2023275715A1 (en)	2021-06-30	2023-01-05	Pfizer Inc.	Metabolites of selective androgen receptor modulators

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH443281A (de) *	1964-02-18	1967-09-15	Hoffmann La Roche	Verfahren zur Herstellung von Dibenzocycloheptatrienverbindungen
US3335148A (en) *	1966-02-17	1967-08-08	Lilly Co Eli	9(3-pyridyl)derivative of fluorene, 9-fluorenol, xanthene, 9-xanthenol and the corresponding nonphytotoxic acid addition salts thereof
US5698551A (en) *	1995-04-07	1997-12-16	Novo Nordisk A/S	Heterocyclic compounds
PT910563E (pt) *	1995-06-29	2003-09-30	Smithkline Beecham Corp	Antagonistas de receptores de integrina
US5659033A (en) *	1995-09-13	1997-08-19	Neurogen Corporation	N-aminoalkylfluorenecarboxamides; a new class of dopamine receptor subtype specific ligands
JP2001501951A (ja) *	1996-10-07	2001-02-13	スミスクライン・ビーチャム・コーポレイション	骨形成刺激方法
CO4920232A1 (es) *	1997-01-08	2000-05-29	Smithkline Beecham Corp	Acidos aceticos dibenzo [a,d] cicloheptano con actividad antagonista del receptor de vitronectin

1998
- 1998-09-16 DZ DZ980219A patent/DZ2609A1/xx active
- 1998-09-16 PE PE1998000881A patent/PE122699A1/es not_active Application Discontinuation
- 1998-09-16 AR ARP980104604A patent/AR015446A1/es not_active Application Discontinuation
- 1998-09-18 ID IDW20000468A patent/ID24162A/id unknown
- 1998-09-18 AP APAP/P/2000/001766A patent/AP2000001766A0/en unknown
- 1998-09-18 SK SK408-2000A patent/SK4082000A3/sk unknown
- 1998-09-18 EP EP98947116A patent/EP1025090A4/en not_active Withdrawn
- 1998-09-18 CO CO98053986A patent/CO5011087A1/es unknown
- 1998-09-18 EA EA200000336A patent/EA200000336A1/ru unknown
- 1998-09-18 JP JP2000512816A patent/JP2001517658A/ja not_active Withdrawn
- 1998-09-18 NZ NZ503389A patent/NZ503389A/en not_active IP Right Cessation
- 1998-09-18 IL IL13502898A patent/IL135028A0/xx unknown
- 1998-09-18 CA CA002303487A patent/CA2303487A1/en not_active Abandoned
- 1998-09-18 BR BR9812340-8A patent/BR9812340A/pt not_active Application Discontinuation
- 1998-09-18 HU HU0003641A patent/HUP0003641A3/hu unknown
- 1998-09-18 KR KR1020007002901A patent/KR20010024141A/ko not_active Ceased
- 1998-09-18 WO PCT/US1998/019466 patent/WO1999015508A1/en not_active Ceased
- 1998-09-18 TR TR2000/00721T patent/TR200000721T2/xx unknown
- 1998-09-18 CN CN98810811A patent/CN1278250A/zh active Pending
- 1998-09-18 AU AU93972/98A patent/AU738433B2/en not_active Ceased
- 1998-09-18 PL PL98339381A patent/PL339381A1/xx unknown
- 1998-09-18 MA MA25266A patent/MA26547A1/fr unknown
- 1998-09-23 TW TW087115535A patent/TW513303B/zh not_active IP Right Cessation
2000
- 2000-03-16 OA OA1200000079A patent/OA11341A/en unknown
- 2000-03-17 NO NO20001407A patent/NO20001407L/no not_active Application Discontinuation
- 2000-04-07 BG BG104314A patent/BG104314A/xx unknown

Also Published As

Publication number	Publication date
CN1278250A (zh)	2000-12-27
EP1025090A1 (en)	2000-08-09
AU738433B2 (en)	2001-09-20
CA2303487A1 (en)	1999-04-01
JP2001517658A (ja)	2001-10-09
NO20001407D0 (no)	2000-03-17
CO5011087A1 (es)	2001-02-28
KR20010024141A (ko)	2001-03-26
WO1999015508A1 (en)	1999-04-01
AR015446A1 (es)	2001-05-02
TR200000721T2 (tr)	2000-11-21
EA200000336A1 (ru)	2000-10-30
AU9397298A (en)	1999-04-12
BR9812340A (pt)	2001-12-18
TW513303B (en)	2002-12-11
ID24162A (id)	2000-07-13
HUP0003641A2 (en)	2001-03-28
PE122699A1 (es)	2000-02-12
MA26547A1 (fr)	2004-12-20
AP2000001766A0 (en)	1998-09-18
EP1025090A4 (en)	2000-11-08
BG104314A (en)	2001-01-31
HUP0003641A3 (en)	2002-10-28
NZ503389A (en)	2002-03-28
OA11341A (en)	2003-12-10
IL135028A0 (en)	2001-05-20
NO20001407L (no)	2000-03-17
PL339381A1 (en)	2000-12-18
SK4082000A3 (en)	2000-09-12

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MA26715A1 (fr)	2004-12-20	Composes chimiques nouveaux modulateurs de ccr5, et compositions pharmaceutiques les contenant.
FR2805818B1 (fr)	2002-04-26	Derives d'azetidine, leur preparation et les compositions pharmaceutiques les contenant
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