DZ2954A1 - Antagoniste des recepteurs de vitronectine, procédé pour sa préparation et compositions pharmaceutiques le contenant. - Google Patents

Antagoniste des recepteurs de vitronectine, procédé pour sa préparation et compositions pharmaceutiques le contenant.

Info

Publication number
DZ2954A1
DZ2954A1 DZ990254A DZ990254A DZ2954A1 DZ 2954 A1 DZ2954 A1 DZ 2954A1 DZ 990254 A DZ990254 A DZ 990254A DZ 990254 A DZ990254 A DZ 990254A DZ 2954 A1 DZ2954 A1 DZ 2954A1
Authority
DZ
Algeria
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
receptor antagonist
vitronectin receptor
Prior art date
Application number
DZ990254A
Other languages
English (en)
Inventor
William H Miller
Peter J Manley
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of DZ2954A1 publication Critical patent/DZ2954A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
DZ990254A 1998-12-04 1999-12-01 Antagoniste des recepteurs de vitronectine, procédé pour sa préparation et compositions pharmaceutiques le contenant. DZ2954A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11090398P 1998-12-04 1998-12-04

Publications (1)

Publication Number Publication Date
DZ2954A1 true DZ2954A1 (fr) 2004-06-20

Family

ID=22335565

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ990254A DZ2954A1 (fr) 1998-12-04 1999-12-01 Antagoniste des recepteurs de vitronectine, procédé pour sa préparation et compositions pharmaceutiques le contenant.

Country Status (39)

Country Link
US (1) US6495560B1 (fr)
EP (1) EP1146874B1 (fr)
JP (1) JP4481504B2 (fr)
KR (1) KR100620485B1 (fr)
CN (1) CN1147300C (fr)
AP (1) AP1534A (fr)
AR (1) AR035006A1 (fr)
AT (1) ATE277043T1 (fr)
AU (1) AU754408B2 (fr)
BG (1) BG65118B1 (fr)
BR (1) BR9915879A (fr)
CA (1) CA2353415A1 (fr)
CO (1) CO5150166A1 (fr)
CZ (1) CZ20011963A3 (fr)
DE (1) DE69920518T2 (fr)
DK (1) DK1146874T3 (fr)
DZ (1) DZ2954A1 (fr)
EA (1) EA003254B1 (fr)
EG (1) EG24025A (fr)
ES (1) ES2229798T3 (fr)
HK (1) HK1042037B (fr)
HU (1) HUP0104804A3 (fr)
ID (1) ID28811A (fr)
IL (2) IL143390A0 (fr)
MA (1) MA25265A1 (fr)
NO (1) NO318895B1 (fr)
NZ (1) NZ511876A (fr)
OA (1) OA11724A (fr)
PE (1) PE20001563A1 (fr)
PL (1) PL195973B1 (fr)
PT (1) PT1146874E (fr)
SI (1) SI1146874T1 (fr)
SK (1) SK7452001A3 (fr)
TR (1) TR200101654T2 (fr)
TW (1) TW482673B (fr)
UA (1) UA71586C2 (fr)
UY (1) UY25824A1 (fr)
WO (1) WO2000033838A1 (fr)
ZA (1) ZA200104398B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY26780A1 (es) * 2000-06-15 2002-01-31 Pharmacia Corp Cicloalquil avb3 antagonistas
JP2004513953A (ja) * 2000-10-24 2004-05-13 メルク エンド カムパニー インコーポレーテッド ジベンズオキサゼピンαVインテグリン受容体アンタゴニスト
NZ539682A (en) 2001-01-29 2006-03-31 Dimensional Pharm Inc Substituted indoles and their use as integrin antagonists
US6872730B2 (en) 2001-04-27 2005-03-29 3-Dimensional Pharmaceuticals, Inc. Substituted benzofurans and benzothiophenes, methods of making and methods of use as integrin antagonists
US20040224986A1 (en) 2002-08-16 2004-11-11 Bart De Corte Piperidinyl targeting compounds that selectively bind integrins
EP1572690A1 (fr) 2002-12-20 2005-09-14 Pharmacia Corporation Composés de thiazole en tant que dérives d'antagonistes des récepteurs de l'integrine
GB0319069D0 (en) * 2003-08-14 2003-09-17 Glaxo Group Ltd Therapeutically useful compounds
TW200635902A (en) * 2004-12-21 2006-10-16 Smithkline Beecham Corp Methods and formulations
EP2593452B1 (fr) 2010-07-14 2017-01-18 Novartis AG Composés hétérocycliques agonistes du récepteur ip
AR089698A1 (es) 2012-01-13 2014-09-10 Novartis Ag Compuestos heterociclicos antagonistas del receptor ip
ES2637719T3 (es) 2013-02-13 2017-10-16 Novartis Ag Compuestos heterocíclicos agonistas del receptor IP
PL3050878T3 (pl) 2013-09-24 2022-01-24 Fujifilm Corporation Zawierający atom azotu związek lub jego sól, lub ich kompleks z metalem

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2687154B1 (fr) * 1992-02-07 1995-05-12 Rhone Poulenc Rorer Sa Nouveau derive de l'isoindolinone, sa preparation et les compositions pharmaceutiques qui le contiennent.
PT910563E (pt) 1995-06-29 2003-09-30 Smithkline Beecham Corp Antagonistas de receptores de integrina
WO1998013278A1 (fr) * 1996-09-27 1998-04-02 Merkler, H. Cuve pour liquides, en particulier pour liquides chimiquement corrosifs
JP2001501951A (ja) * 1996-10-07 2001-02-13 スミスクライン・ビーチャム・コーポレイション 骨形成刺激方法
UY24949A1 (es) 1997-04-08 2001-04-30 Smithkline Beecham Corp Compuestos calcilíticos

Also Published As

Publication number Publication date
NZ511876A (en) 2004-02-27
EP1146874A4 (fr) 2002-06-05
JP2003523931A (ja) 2003-08-12
HUP0104804A3 (en) 2002-12-28
EA200100618A1 (ru) 2001-12-24
HK1042037B (en) 2005-07-29
CZ20011963A3 (cs) 2001-11-14
ES2229798T3 (es) 2005-04-16
AU1750200A (en) 2000-06-26
BR9915879A (pt) 2002-02-13
CO5150166A1 (es) 2002-04-29
PL195973B1 (pl) 2007-11-30
KR100620485B1 (ko) 2006-09-13
AR035006A1 (es) 2004-04-14
DE69920518D1 (de) 2004-10-28
AP1534A (en) 2006-01-09
TW482673B (en) 2002-04-11
CN1334730A (zh) 2002-02-06
ATE277043T1 (de) 2004-10-15
US6495560B1 (en) 2002-12-17
EG24025A (en) 2008-03-26
ID28811A (id) 2001-07-05
EP1146874A1 (fr) 2001-10-24
BG65118B1 (bg) 2007-03-30
PT1146874E (pt) 2005-02-28
UY25824A1 (es) 2001-07-31
AU754408B2 (en) 2002-11-14
NO318895B1 (no) 2005-05-18
JP4481504B2 (ja) 2010-06-16
NO20012732D0 (no) 2001-06-01
CA2353415A1 (fr) 2000-06-15
PE20001563A1 (es) 2001-02-09
EP1146874B1 (fr) 2004-09-22
EA003254B1 (ru) 2003-02-27
HUP0104804A2 (hu) 2002-05-29
MA25265A1 (fr) 2001-10-01
BG105651A (en) 2002-02-28
IL143390A (en) 2006-07-05
SI1146874T1 (en) 2005-04-30
SK7452001A3 (en) 2001-12-03
NO20012732L (no) 2001-08-01
KR20010080669A (ko) 2001-08-22
WO2000033838A1 (fr) 2000-06-15
ZA200104398B (en) 2002-05-29
DE69920518T2 (de) 2005-09-22
IL143390A0 (en) 2002-04-21
DK1146874T3 (da) 2005-01-31
UA71586C2 (en) 2004-12-15
HK1042037A1 (en) 2002-08-02
TR200101654T2 (tr) 2002-03-21
OA11724A (en) 2005-01-26
PL348702A1 (en) 2002-06-03
CN1147300C (zh) 2004-04-28

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