DZ3489A1 - Procede de preparation de mesylates de derives de piperazine - Google Patents

Procede de preparation de mesylates de derives de piperazine

Info

Publication number
DZ3489A1
DZ3489A1 DZ023489A DZ023489A DZ3489A1 DZ 3489 A1 DZ3489 A1 DZ 3489A1 DZ 023489 A DZ023489 A DZ 023489A DZ 023489 A DZ023489 A DZ 023489A DZ 3489 A1 DZ3489 A1 DZ 3489A1
Authority
DZ
Algeria
Prior art keywords
mesylates
preparation
piperazine derivatives
piperazine
derivatives
Prior art date
Application number
DZ023489A
Other languages
English (en)
Inventor
Marcel P M Van Aar
Stefanus J Schouten
Jan Zorgdrager
Michiel C Heslinga
Original Assignee
Solvay Pharm Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Bv filed Critical Solvay Pharm Bv
Application granted granted Critical
Publication of DZ3489A1 publication Critical patent/DZ3489A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DZ023489A 2001-02-16 2002-02-14 Procede de preparation de mesylates de derives de piperazine DZ3489A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01200534 2001-02-16
PCT/EP2002/001666 WO2002066449A2 (fr) 2001-02-16 2002-02-14 Procede de preparation de mesylates de derives de piperazine

Publications (1)

Publication Number Publication Date
DZ3489A1 true DZ3489A1 (fr) 2002-08-29

Family

ID=8179894

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ023489A DZ3489A1 (fr) 2001-02-16 2002-02-14 Procede de preparation de mesylates de derives de piperazine

Country Status (34)

Country Link
US (1) US7030241B2 (fr)
EP (1) EP1362040B1 (fr)
JP (1) JP4328528B2 (fr)
KR (2) KR100859106B1 (fr)
CN (1) CN1176079C (fr)
AR (1) AR034206A1 (fr)
AT (1) ATE284875T1 (fr)
AU (1) AU2002250962B2 (fr)
BG (1) BG66101B1 (fr)
BR (1) BR0205683A (fr)
CA (1) CA2422703C (fr)
CZ (1) CZ301780B6 (fr)
DE (1) DE60202261T2 (fr)
DK (1) DK1362040T3 (fr)
DZ (1) DZ3489A1 (fr)
ES (1) ES2230481T3 (fr)
HR (1) HRP20030610B1 (fr)
HU (1) HUP0400772A3 (fr)
IL (1) IL153509A (fr)
IS (1) IS2417B (fr)
ME (1) MEP37508A (fr)
MX (1) MXPA03002359A (fr)
MY (1) MY130687A (fr)
NO (1) NO324460B1 (fr)
NZ (1) NZ524632A (fr)
PL (1) PL208363B1 (fr)
PT (1) PT1362040E (fr)
RS (1) RS51126B (fr)
RU (1) RU2272036C2 (fr)
SI (1) SI1362040T1 (fr)
SK (1) SK286143B6 (fr)
UA (1) UA75390C2 (fr)
WO (1) WO2002066449A2 (fr)
ZA (1) ZA200301590B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR045362A1 (es) * 2003-08-18 2005-10-26 Solvay Pharm Bv Forma cristalina estable de mesilato de bifeprunox (monometansulfonato de 7-[4-([1,1- bifenil] -3- ilmetil) -1- piperazinil] - 2-(3h) -benzoxazolona
US7435738B2 (en) 2003-08-18 2008-10-14 Solvay Pharmaceuticals, Inc. Stable crystalline form of bifeprunox mesylate (7-[4-([1,1′-biphenyl]-3-ylmethyl)-1-piperazinyl]-2(3H)-benzoxazolone monomethanesulfonate)
US7405216B2 (en) * 2004-08-18 2008-07-29 Solvay Pharmaceuticals, B.V. Stable crystalline form of bifeprunox mesylate (7-[4-([1,1′-biphenyl]-3-ylmethyl)-1-piperazinyl]-2(3H)-benzoxazolone monomethanesulfonate)
US7964604B2 (en) * 2005-02-18 2011-06-21 Solvay Pharmaceuticals B.V. Bifeprunox mesylate maintenance dose compositions and methods for using the same
US7423040B2 (en) * 2005-02-18 2008-09-09 Irene Eijgendaal Stable crystalline form of bifeprunox mesylate, dosage forms thereof and methods for using same
US20070275977A1 (en) * 2006-05-02 2007-11-29 Van Aar Marcel P N-oxides of pyridylmethyl -piperazine and -piperidine derivatives
US8106056B2 (en) * 2006-06-16 2012-01-31 Solvay Pharmaceuticals B.V. Combination preparations comprising bifeprunox and a dopamine agonist
US7786126B2 (en) * 2006-06-16 2010-08-31 Solvay Pharmaceuticals B.V. Combination preparations comprising SLV308 and a dopamine agonist
US20090068290A1 (en) * 2006-08-31 2009-03-12 Michel Bourin Bifeprunox doses for treating schizophrenia
AU2007291234A1 (en) 2006-08-31 2008-03-06 Solvay Pharmaceuticals B.V. Titration schedule for bifeprunox for treating schizophrenia and kits for use therein
US20080132520A1 (en) * 2006-08-31 2008-06-05 Winsemius Antje A Compositions, kits and methods for administering a titration schedule comprising bifeprunox compounds
EA018974B9 (ru) 2008-02-05 2014-04-30 Харбор Терапьютикс, Инк. Твердые лекарственные формы
WO2011023796A1 (fr) 2009-08-31 2011-03-03 Abbott Healthcare Products B.V. Bifeprunox destiné au traitement de l'addiction
UY32935A (es) 2009-10-12 2011-05-31 Abbott Healthcare Products Bv Polimorfos de pardoprunox

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0185429A1 (fr) * 1984-12-21 1986-06-25 Duphar International Research B.V Pipérazines bicycliques
DE3586794T2 (de) 1984-12-21 1993-05-27 Duphar Int Res Arzneimittel mit psychotroper wirkung.
JPH0344383A (ja) * 1989-07-12 1991-02-26 Ihara Chem Ind Co Ltd ５―トリフルオロメチル―２―ハロメチルベンゾチアゾール類の製造法
JP3044383B2 (ja) * 1990-05-22 2000-05-22 コニカ株式会社 含窒素６員環化合物の製造方法
GB9200293D0 (en) * 1992-01-08 1992-02-26 Wyeth John & Brother Ltd Piperazine derivatives
DE69736704T2 (de) * 1996-03-29 2007-09-13 Duphar International Research B.V. Piperazin- und piperidin- derivate
SE9702799D0 (sv) * 1997-07-25 1997-07-25 Astra Ab New compounds
UA71590C2 (en) * 1998-11-13 2004-12-15 Duphar Int Res Piperazine and piperidine derivatives
US7435738B2 (en) * 2003-08-18 2008-10-14 Solvay Pharmaceuticals, Inc. Stable crystalline form of bifeprunox mesylate (7-[4-([1,1′-biphenyl]-3-ylmethyl)-1-piperazinyl]-2(3H)-benzoxazolone monomethanesulfonate)

Also Published As

Publication number Publication date
HK1059934A1 (en) 2004-07-23
DE60202261D1 (de) 2005-01-20
PL369330A1 (en) 2005-04-18
ES2230481T3 (es) 2005-05-01
WO2002066449A3 (fr) 2002-10-24
MXPA03002359A (es) 2003-06-30
NO324460B1 (no) 2007-10-22
RU2272036C2 (ru) 2006-03-20
EP1362040A2 (fr) 2003-11-19
SI1362040T1 (en) 2005-06-30
AU2002250962B2 (en) 2006-08-24
CA2422703C (fr) 2010-04-13
BR0205683A (pt) 2004-07-06
US7030241B2 (en) 2006-04-18
KR20030077523A (ko) 2003-10-01
KR20080064206A (ko) 2008-07-08
IL153509A0 (en) 2003-07-06
DE60202261T2 (de) 2005-05-19
BG66101B1 (bg) 2011-04-29
ATE284875T1 (de) 2005-01-15
DK1362040T3 (da) 2005-01-24
MY130687A (en) 2007-07-31
RS51126B (sr) 2010-10-31
NO20031754L (no) 2003-04-15
MEP37508A (en) 2011-02-10
CZ2003697A3 (cs) 2003-06-18
CN1463268A (zh) 2003-12-24
CA2422703A1 (fr) 2002-08-29
WO2002066449A2 (fr) 2002-08-29
HRP20030610B1 (en) 2006-02-28
PT1362040E (pt) 2005-05-31
KR101000733B1 (ko) 2010-12-14
AR034206A1 (es) 2004-02-04
HRP20030610A2 (en) 2005-06-30
US20040077631A1 (en) 2004-04-22
CN1176079C (zh) 2004-11-17
KR100859106B1 (ko) 2008-09-18
HUP0400772A2 (hu) 2004-08-30
PL208363B1 (pl) 2011-04-29
IS6876A (is) 2003-07-17
IL153509A (en) 2007-12-03
NO20031754D0 (no) 2003-04-15
HUP0400772A3 (en) 2008-02-28
UA75390C2 (en) 2006-04-17
SK286143B6 (sk) 2008-04-07
ZA200301590B (en) 2004-02-05
NZ524632A (en) 2004-03-26
JP2004518741A (ja) 2004-06-24
EP1362040B1 (fr) 2004-12-15
IS2417B (is) 2008-10-15
SK3092003A3 (en) 2003-09-11
JP4328528B2 (ja) 2009-09-09
BG108090A (bg) 2004-12-30
YU64403A (sh) 2006-05-25
CZ301780B6 (cs) 2010-06-23

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