EA036704B1 - Способ лечения неалкогольной жировой болезни печени и неалкогольного стеатогепатита - Google Patents

Способ лечения неалкогольной жировой болезни печени и неалкогольного стеатогепатита Download PDF

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Publication number
EA036704B1
EA036704B1 EA201692050A EA201692050A EA036704B1 EA 036704 B1 EA036704 B1 EA 036704B1 EA 201692050 A EA201692050 A EA 201692050A EA 201692050 A EA201692050 A EA 201692050A EA 036704 B1 EA036704 B1 EA 036704B1
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EA
Eurasian Patent Office
Prior art keywords
nash
nafld
mbx
treatment
alcoholic
Prior art date
Application number
EA201692050A
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English (en)
Russian (ru)
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EA201692050A1 (ru
Inventor
Брайан Робертс
Сюэянь Ванг
Юнь-Цзюн Чой
Дэвид Карпф
Роберт Мартин
Чарльз А. Макуэртер
Original Assignee
Саймабэй Терапьютикс, Инк.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53373532&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA036704(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Саймабэй Терапьютикс, Инк. filed Critical Саймабэй Терапьютикс, Инк.
Publication of EA201692050A1 publication Critical patent/EA201692050A1/ru
Publication of EA036704B1 publication Critical patent/EA036704B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EA201692050A 2014-04-11 2015-04-10 Способ лечения неалкогольной жировой болезни печени и неалкогольного стеатогепатита EA036704B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461978335P 2014-04-11 2014-04-11
PCT/US2015/025416 WO2015157697A1 (en) 2014-04-11 2015-04-10 Treatment of nafld and nash

Publications (2)

Publication Number Publication Date
EA201692050A1 EA201692050A1 (ru) 2017-01-30
EA036704B1 true EA036704B1 (ru) 2020-12-10

Family

ID=53373532

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201692050A EA036704B1 (ru) 2014-04-11 2015-04-10 Способ лечения неалкогольной жировой болезни печени и неалкогольного стеатогепатита

Country Status (27)

Country Link
US (7) US9381181B2 (2)
EP (1) EP3129018B1 (2)
JP (1) JP6865038B2 (2)
KR (1) KR102374499B1 (2)
CN (1) CN106163508A (2)
AU (1) AU2015243239B2 (2)
BR (1) BR112016023269A8 (2)
CA (1) CA2944139C (2)
CL (1) CL2016002517A1 (2)
CY (1) CY1122602T1 (2)
DK (1) DK3129018T3 (2)
EA (1) EA036704B1 (2)
ES (1) ES2764467T3 (2)
HR (1) HRP20192299T1 (2)
IL (1) IL248193B (2)
LT (1) LT3129018T (2)
MX (1) MX369921B (2)
NZ (1) NZ724740A (2)
PH (1) PH12016501978B1 (2)
PL (1) PL3129018T3 (2)
PT (1) PT3129018T (2)
RS (1) RS59637B1 (2)
SG (1) SG11201608077PA (2)
SI (1) SI3129018T1 (2)
SM (1) SMT202000019T1 (2)
UA (1) UA121208C2 (2)
WO (1) WO2015157697A1 (2)

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EP3129018A1 (en) 2017-02-15
MX369921B (es) 2019-11-26
US20160324812A1 (en) 2016-11-10
KR102374499B1 (ko) 2022-03-14
US20150290154A1 (en) 2015-10-15
PH12016501978B1 (en) 2023-07-12
SG11201608077PA (en) 2016-10-28
CA2944139A1 (en) 2015-10-15
CA2944139C (en) 2020-11-03
IL248193B (en) 2019-03-31
AU2015243239B2 (en) 2019-11-14
US10342770B2 (en) 2019-07-09
AU2015243239A1 (en) 2016-10-20
US9962346B2 (en) 2018-05-08
SI3129018T1 (sl) 2020-02-28
SMT202000019T1 (it) 2020-03-13
WO2015157697A1 (en) 2015-10-15
DK3129018T3 (da) 2020-01-20
PH12016501978A1 (en) 2016-12-19
EA201692050A1 (ru) 2017-01-30
US9616039B2 (en) 2017-04-11
US11179359B2 (en) 2021-11-23
PL3129018T3 (pl) 2020-05-18
CN106163508A (zh) 2016-11-23
ES2764467T3 (es) 2020-06-03
CL2016002517A1 (es) 2017-05-05
LT3129018T (lt) 2020-01-10
PT3129018T (pt) 2020-01-15
JP6865038B2 (ja) 2021-04-28
MX2016013375A (es) 2017-02-15
RS59637B1 (sr) 2020-01-31
US20200009092A1 (en) 2020-01-09
UA121208C2 (uk) 2020-04-27
CY1122602T1 (el) 2021-03-12
US9381181B2 (en) 2016-07-05
HRP20192299T1 (hr) 2020-03-06
US10188620B2 (en) 2019-01-29
BR112016023269A2 (pt) 2017-08-15
US20180008566A1 (en) 2018-01-11
EP3129018B1 (en) 2019-10-23
US20210038546A1 (en) 2021-02-11
US20190142776A1 (en) 2019-05-16
US10722483B2 (en) 2020-07-28
KR20160136451A (ko) 2016-11-29
BR112016023269A8 (pt) 2021-06-29
NZ724740A (en) 2019-11-29
US20180228752A1 (en) 2018-08-16
JP2017513836A (ja) 2017-06-01

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