EA200401357A1 - Болеутоляющая композиция для перорального применения с регулируемым высвобождением опиоида - Google Patents

Болеутоляющая композиция для перорального применения с регулируемым высвобождением опиоида

Info

Publication number
EA200401357A1
EA200401357A1 EA200401357A EA200401357A EA200401357A1 EA 200401357 A1 EA200401357 A1 EA 200401357A1 EA 200401357 A EA200401357 A EA 200401357A EA 200401357 A EA200401357 A EA 200401357A EA 200401357 A1 EA200401357 A1 EA 200401357A1
Authority
EA
Eurasian Patent Office
Prior art keywords
composition
survival
frozen
oral application
opioid
Prior art date
Application number
EA200401357A
Other languages
English (en)
Other versions
EA006846B1 (ru
Inventor
Любослав Разус
Ондрей Гаттнар
Иван Варга
Микулаш Легоцкий
Вера Корманова
Вера Губинова
Original Assignee
Зентива, А. С.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Зентива, А. С. filed Critical Зентива, А. С.
Publication of EA200401357A1 publication Critical patent/EA200401357A1/ru
Publication of EA006846B1 publication Critical patent/EA006846B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)

Abstract

Изобретение описывает композицию и способ получения твердой фармацевтической композиции для перорального применения с регулируемым высвобождением активного вещества, которая содержит дигидрокодеин и его фармацевтически приемлемые соли в требуемом количестве, вместе с микронизированным эфиром глицерина и бегеновой кислоты, дигидратом фосфата кальция, сополимером винилпирролидона и винилацетата и натриевой солью сложного эфира фумаровой кислоты и стеарилового спирта.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200401357A 2002-04-12 2003-04-10 Болеутоляющая композиция для перорального применения с регулируемым высвобождением опиоида EA006846B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SK501-2002A SK286107B6 (sk) 2002-04-12 2002-04-12 Analgeticky účinný perorálny liečivý prípravok s kontrolovaným uvoľňovaním opioidnej účinnej látky a spôsob jeho prípravy
PCT/SK2003/000008 WO2003086365A1 (en) 2002-04-12 2003-04-10 Analgesical oral composition with controlled release of an opioid

Publications (2)

Publication Number Publication Date
EA200401357A1 true EA200401357A1 (ru) 2005-04-28
EA006846B1 EA006846B1 (ru) 2006-04-28

Family

ID=29247067

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200401357A EA006846B1 (ru) 2002-04-12 2003-04-10 Болеутоляющая композиция для перорального применения с регулируемым высвобождением опиоида

Country Status (13)

Country Link
EP (1) EP1494656B1 (ru)
AT (1) ATE398446T1 (ru)
AU (1) AU2003219641A1 (ru)
CZ (1) CZ20041054A3 (ru)
DE (1) DE60321672D1 (ru)
EA (1) EA006846B1 (ru)
GE (1) GEP20063991B (ru)
HU (1) HUP0500438A3 (ru)
NO (1) NO20044502L (ru)
PL (1) PL372698A1 (ru)
SK (1) SK286107B6 (ru)
UA (1) UA74991C2 (ru)
WO (1) WO2003086365A1 (ru)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3750145T2 (de) * 1986-06-10 1994-11-03 Euro Celtique Sa Zusammensetzung mit kontrollierter Freisetzung von Dihydrocodein.
FR2753904B1 (fr) * 1996-10-01 1998-10-30 Gattefosse Ets Sa Composition pharmaceutique a liberation modifiee de principe actif, comportant une matrice, et procede de fabrication
DE19747261A1 (de) * 1997-10-25 1999-04-29 Bayer Ag Osmotisches Arzneimittelfreisetzungssystem
KR100889069B1 (ko) * 1999-10-29 2009-03-17 유로-셀티크 소시에떼 아노뉨 서방성 하이드로코돈 제형
SK285128B6 (sk) * 1999-12-28 2006-07-07 Zentiva, A. S. Liečivý prípravok s riadeným uvoľňovaním obsahujúci tramadol hydrochlorid a spôsob jeho prípravy

Also Published As

Publication number Publication date
ATE398446T1 (de) 2008-07-15
SK286107B6 (sk) 2008-03-05
NO20044502L (no) 2004-10-26
EP1494656A1 (en) 2005-01-12
UA74991C2 (en) 2006-02-15
SK5012002A3 (en) 2003-11-04
AU2003219641A1 (en) 2003-10-27
CZ20041054A3 (cs) 2005-01-12
PL372698A1 (en) 2005-07-25
HUP0500438A2 (hu) 2005-08-29
HUP0500438A3 (en) 2008-03-28
WO2003086365A1 (en) 2003-10-23
EP1494656B1 (en) 2008-06-18
DE60321672D1 (de) 2008-07-31
GEP20063991B (en) 2006-12-11
EA006846B1 (ru) 2006-04-28

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KG TJ TM