EA201190285A1 - Иммуногенные композиции, имеющие низкую концентрацию хлорида натрия - Google Patents

Иммуногенные композиции, имеющие низкую концентрацию хлорида натрия

Info

Publication number
EA201190285A1
EA201190285A1 EA201190285A EA201190285A EA201190285A1 EA 201190285 A1 EA201190285 A1 EA 201190285A1 EA 201190285 A EA201190285 A EA 201190285A EA 201190285 A EA201190285 A EA 201190285A EA 201190285 A1 EA201190285 A1 EA 201190285A1
Authority
EA
Eurasian Patent Office
Prior art keywords
sodium chloride
immunogenous
compositions
low concentration
concentration
Prior art date
Application number
EA201190285A
Other languages
English (en)
Inventor
Вероник Эндерикс
Доминик Ингрид Лемуан
Original Assignee
Глаксосмитклайн Байолоджикалс С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Глаксосмитклайн Байолоджикалс С.А. filed Critical Глаксосмитклайн Байолоджикалс С.А.
Publication of EA201190285A1 publication Critical patent/EA201190285A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K39/001188—NY-ESO
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
    • A61K39/001189—PRAME
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

Предложены иммуногенные композиции, содержащие антиген, где концентрация хлорида натрия или ионная сила композиции составляет менее 100 мМ, и их применение в медицине.
EA201190285A 2009-06-10 2010-06-08 Иммуногенные композиции, имеющие низкую концентрацию хлорида натрия EA201190285A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0910045.4A GB0910045D0 (en) 2009-06-10 2009-06-10 Novel compositions
PCT/EP2010/058018 WO2010142686A1 (en) 2009-06-10 2010-06-08 Immunogenic compositions having low sodium chloride concentration

Publications (1)

Publication Number Publication Date
EA201190285A1 true EA201190285A1 (ru) 2012-06-29

Family

ID=40937236

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201190285A EA201190285A1 (ru) 2009-06-10 2010-06-08 Иммуногенные композиции, имеющие низкую концентрацию хлорида натрия

Country Status (15)

Country Link
US (1) US20120093921A1 (ru)
EP (1) EP2440243A1 (ru)
JP (1) JP2012529465A (ru)
KR (1) KR20120031498A (ru)
CN (1) CN102802660A (ru)
AU (1) AU2010257539A1 (ru)
BR (1) BRPI1013051A2 (ru)
CA (1) CA2764251A1 (ru)
EA (1) EA201190285A1 (ru)
GB (1) GB0910045D0 (ru)
IL (1) IL216028A0 (ru)
MX (1) MX2011013161A (ru)
SG (1) SG176091A1 (ru)
WO (1) WO2010142686A1 (ru)
ZA (1) ZA201108504B (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0910046D0 (en) * 2009-06-10 2009-07-22 Glaxosmithkline Biolog Sa Novel compositions
CA2819297A1 (en) * 2010-12-14 2012-06-21 Glaxosmithkline Biologicals S.A. Mycobacterium antigenic composition
CN103717613A (zh) * 2011-07-22 2014-04-09 葛兰素史密丝克莱恩生物有限公司 Prame纯化
GB201318858D0 (en) * 2013-10-25 2013-12-11 Glaxosmithkline Biolog Sa Calcium fluoride compositions
GB201522068D0 (en) * 2015-12-15 2016-01-27 Glaxosmithkline Biolog Sa Dried composition
CA3045952A1 (en) * 2016-12-07 2018-06-14 Glaxosmithkline Biologicals Sa Novel process
GB201707700D0 (en) 2017-05-12 2017-06-28 Glaxosmithkline Biologicals Sa Dried composition
JP2020521781A (ja) 2017-05-30 2020-07-27 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム リポソームに内包されたｒｎａを製造する方法
FR3066920A1 (fr) 2017-05-30 2018-12-07 Glaxosmithkline Biologicals S.A. Nouveaux procedes de fabrication d'un adjuvant
WO2020109365A1 (en) * 2018-11-29 2020-06-04 Glaxosmithkline Biologicals Sa Methods for manufacturing an adjuvant
EP4021407A1 (en) 2019-08-30 2022-07-06 GlaxoSmithKline Biologicals S.A. Jet mixing lipid nanoparticle manufacturing process

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA56132C2 (ru) * 1995-04-25 2003-05-15 Смітклайн Бічем Байолоджікалс С.А. Композиция вакцины (варианты), способ стабилизации qs21 по отношению к гидролизу (варианты), способ приготовления вакцины
DE19803453A1 (de) * 1998-01-30 1999-08-12 Boehringer Ingelheim Int Vakzine
DK1075276T3 (da) * 1998-05-07 2008-02-11 Corixa Corp Adjuvanssammensætning og fremgangsmåder til dens anvendelse
GB0411411D0 (en) * 2004-05-21 2004-06-23 Glaxosmithkline Biolog Sa Vaccines
WO2008142433A1 (en) * 2007-05-24 2008-11-27 Loders Croklaan B.V. Process for producing compositions comprising tocoherols and tocotrienols
CA2687632C (en) * 2007-05-24 2013-01-15 Glaxosmithkline Biologicals S.A. Lyophilised antigen composition

Also Published As

Publication number Publication date
EP2440243A1 (en) 2012-04-18
JP2012529465A (ja) 2012-11-22
CN102802660A (zh) 2012-11-28
IL216028A0 (en) 2012-01-31
GB0910045D0 (en) 2009-07-22
ZA201108504B (en) 2013-04-24
MX2011013161A (es) 2012-01-30
AU2010257539A1 (en) 2011-12-01
US20120093921A1 (en) 2012-04-19
WO2010142686A1 (en) 2010-12-16
SG176091A1 (en) 2011-12-29
BRPI1013051A2 (pt) 2016-04-05
CA2764251A1 (en) 2010-12-16
KR20120031498A (ko) 2012-04-03

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