EA201400869A1 - Масляная дисперсия, способ её получения, упаковка и применение борной кислоты в качестве стимулятора консервации масляной дисперсии - Google Patents

Масляная дисперсия, способ её получения, упаковка и применение борной кислоты в качестве стимулятора консервации масляной дисперсии

Info

Publication number
EA201400869A1
EA201400869A1 EA201400869A EA201400869A EA201400869A1 EA 201400869 A1 EA201400869 A1 EA 201400869A1 EA 201400869 A EA201400869 A EA 201400869A EA 201400869 A EA201400869 A EA 201400869A EA 201400869 A1 EA201400869 A1 EA 201400869A1
Authority
EA
Eurasian Patent Office
Prior art keywords
oil dispersion
boric acid
stimulator
conservation
packaging
Prior art date
Application number
EA201400869A
Other languages
English (en)
Inventor
Жан-Себастьян Гарриг
Фредерик Лаллеман
Бетти Филипс
Original Assignee
Сантен Сас
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Сантен Сас filed Critical Сантен Сас
Publication of EA201400869A1 publication Critical patent/EA201400869A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/22—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Colloid Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Описана самоконсервируемая масляная дисперсия. В частности, описана самоконсервируемая масляная дисперсия, содержащая дисперсную масляную фазу, водную фазу и по меньшей мере одно поверхностно-активное вещество, при этом масляная дисперсия содержит борную кислоту в количестве от 0,005 до 0,075% от общей массы масляной дисперсии, количество которой является эффективным консервирующим количеством для придания консервирующей способности масляной дисперсии.
EA201400869A 2012-02-23 2013-02-22 Масляная дисперсия, способ её получения, упаковка и применение борной кислоты в качестве стимулятора консервации масляной дисперсии EA201400869A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261602369P 2012-02-23 2012-02-23
EP12156652.5A EP2630952A1 (en) 2012-02-23 2012-02-23 Self-preserved oil dispersions comprising boric acid
PCT/EP2013/053556 WO2013124415A1 (en) 2012-02-23 2013-02-22 Self-preserved oil dispersions comprising boric

Publications (1)

Publication Number Publication Date
EA201400869A1 true EA201400869A1 (ru) 2014-12-30

Family

ID=45656502

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201400869A EA201400869A1 (ru) 2012-02-23 2013-02-22 Масляная дисперсия, способ её получения, упаковка и применение борной кислоты в качестве стимулятора консервации масляной дисперсии

Country Status (19)

Country Link
US (1) US9682147B2 (ru)
EP (2) EP2630952A1 (ru)
JP (2) JP6231499B2 (ru)
KR (1) KR20140124405A (ru)
CN (1) CN104220048A (ru)
AU (1) AU2013224043B2 (ru)
CA (1) CA2862932A1 (ru)
EA (1) EA201400869A1 (ru)
GE (1) GEP20186824B (ru)
HK (2) HK1203154A1 (ru)
IN (1) IN2014DN06853A (ru)
MX (1) MX2014010005A (ru)
MY (1) MY169504A (ru)
NZ (1) NZ627861A (ru)
PH (1) PH12014501906A1 (ru)
SG (1) SG11201405098PA (ru)
TW (1) TWI564032B (ru)
UA (1) UA112669C2 (ru)
WO (1) WO2013124415A1 (ru)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8633178B2 (en) 2011-11-23 2014-01-21 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
EP2630952A1 (en) * 2012-02-23 2013-08-28 Novagali Pharma S.A. Self-preserved oil dispersions comprising boric acid
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
EP3145489A1 (en) 2014-05-22 2017-03-29 TherapeuticsMD, Inc. Natural combination hormone replacement formulations and therapies
RU2016141135A (ru) 2014-07-29 2018-08-28 Терапьютиксмд, Инк. Трансдермальный крем
MX2017010544A (es) * 2015-02-24 2018-06-18 Univ Illinois Metodos y composiciones para tratar la enfermedad del ojo seco y otros trastornos del ojo.
US10004683B2 (en) 2015-06-18 2018-06-26 Common Pharma, Inc. Antimicrobial formulations
WO2016205574A1 (en) * 2015-06-18 2016-12-22 Common Pharma, Inc Antimicrobial formulations
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US10066229B2 (en) * 2015-07-28 2018-09-04 Otonomy, Inc. Treatment using truncated Trk B and Trk C antagonists
WO2017173071A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
ES2704918T3 (es) * 2016-04-15 2019-03-20 Dr Gerhard Mann Chem Pharm Fabrik Gmbh Composición oftálmica estable en almacenamiento
US9821510B2 (en) * 2016-04-18 2017-11-21 Xerox Corporation Using depth in three-dimensional object printing to form colors that change with viewing and illumination angles
BE1024559B1 (nl) * 2017-02-21 2018-04-05 Purna Pharmaceuticals Nv Werkwijze voor het maken van een verstuifbare emulsie omvattende een corticosteroïde, een aminoglycoside en een zuur
CN107019669B (zh) * 2017-04-13 2020-01-21 山东天音生物科技有限公司 一种玉米黄质纳米混悬剂及其制备方法
WO2018212846A1 (en) 2017-05-19 2018-11-22 Ocugen, Inc. Ophthalmic compositions and methods of use
KR102657908B1 (ko) * 2017-11-14 2024-04-17 프로펨 게엠베하 점막 감염을 치료하기 위한 에멀젼
PL3681500T3 (pl) 2018-04-24 2022-08-01 Allergan, Inc. Zastosowanie chlorowodorku pilokarpiny w leczeniu starczowzroczności
MY198184A (en) 2018-09-21 2023-08-09 Petroliam Nasional Berhad Ionic liquids formulation as an environmentally friendly oil dispersant
CN108853016A (zh) * 2018-09-26 2018-11-23 广州大光制药有限公司 一种地夸磷索钠滴眼液及其制备方法
EP3952900A1 (en) * 2019-04-11 2022-02-16 R.P. Scherer Technologies, LLC Formulation for oral delivery of proteins, peptides and small molecules with poor permeability
US20230049050A1 (en) * 2019-12-18 2023-02-16 National Research Council Of Canada Emulsions of bioactive lipophilic compounds including oils
US20230057383A1 (en) * 2020-03-21 2023-02-23 Mihan JAFARI JAVID Composition and methods for prevention and treatment of vascular disorders, neurodegenerative disease and neuropathic disorders
GR1010012B (el) * 2020-05-12 2021-05-27 Φαρματεν Α.Β.Ε.Ε. Φαρμακευτικο σκευασμα ελευθερο συντηρητικου για οφθαλμικη χορηγηση περιεχον κυκλοσπορινη
TWI819317B (zh) * 2021-06-07 2023-10-21 溫士頓醫藥股份有限公司 含前列腺素衍生物的眼用奈米乳劑組合物

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW274516B (ru) 1993-11-12 1996-04-21 Ciba Geigy Ag
PT877600E (pt) * 1996-08-09 2004-02-27 Alcon Mfg Ltd Sistemas conservantes para composicoes farmaceuticas contendo ciclodextrinas
US6379688B2 (en) * 1997-02-28 2002-04-30 Senju Pharmaceutical Co., Ltd. Preservative for emulsion and emulsion containing same
JP4221073B2 (ja) * 1997-02-28 2009-02-12 千寿製薬株式会社 乳剤用保存剤および乳剤
US6166012A (en) 1999-07-30 2000-12-26 Allergan Sales, Inc. Antibiotic compositions and method for using same
DE19954516A1 (de) * 1999-11-12 2001-05-17 Boehringer Ingelheim Int Epinastin-haltige Lösungen
US6528070B1 (en) * 2000-09-15 2003-03-04 Stepan Company Emulsion comprising a ternary surfactant blend of cationic, anionic, and bridging surfactants, oil and water, and methods of preparing same
AU2002350207A1 (en) * 2001-11-19 2003-06-10 Control Delivery Systems, Inc. Topical delivery of codrugs
US20040191332A1 (en) 2003-03-27 2004-09-30 Allergan, Inc. Preserved ophthalmic compositions
US20060233739A1 (en) * 2003-11-24 2006-10-19 Thornfeldt Carl R Treatment of mucocutaneous disorders through reversing chronic imflammation and barrier disruption
US20060141059A1 (en) 2004-12-27 2006-06-29 Alcon, Inc. Self-preserved ophthalmic pharmaceutical compositions containing tobramycin
US20100021561A1 (en) 2006-09-21 2010-01-28 Chowhan Masood A Self-preserved aqueous pharmaceutical compositions
TWI394564B (zh) 2006-09-21 2013-05-01 Alcon Res Ltd 自行保存型水性藥學組成物
WO2008042619A2 (en) * 2006-09-28 2008-04-10 Alcon Research, Ltd. Self-preserved aqueous pharmaceutical compositions
US9629852B2 (en) * 2007-10-16 2017-04-25 Sun Pharma Advanced Research Company Ltd. Ophthalmic composition comprising a prostaglandin
US8669241B2 (en) 2008-12-02 2014-03-11 Rohto Pharmaceutical Co., Ltd. Ophthalmic composition
EP2389939A1 (en) * 2010-05-28 2011-11-30 Novagali Pharma S.A. Use of prostaglandins F2alpha and analogues for the healing of corneal and conjunctival lesions
TWI478730B (zh) * 2009-12-03 2015-04-01 Alcon Res Ltd 眼科乳劑
JP6093701B2 (ja) * 2011-07-08 2017-03-08 ロート製薬株式会社 眼科用水性組成物
EP2630952A1 (en) * 2012-02-23 2013-08-28 Novagali Pharma S.A. Self-preserved oil dispersions comprising boric acid

Also Published As

Publication number Publication date
SG11201405098PA (en) 2014-09-26
TWI564032B (zh) 2017-01-01
CA2862932A1 (en) 2013-08-29
TW201347786A (zh) 2013-12-01
JP2015509494A (ja) 2015-03-30
MY169504A (en) 2019-04-15
KR20140124405A (ko) 2014-10-24
IN2014DN06853A (ru) 2015-05-22
US20150025020A1 (en) 2015-01-22
AU2013224043B2 (en) 2017-07-27
HK1203153A1 (en) 2015-10-23
AU2013224043A1 (en) 2014-08-21
PH12014501906A1 (en) 2014-11-24
HK1203154A1 (en) 2015-10-23
JP2018039828A (ja) 2018-03-15
UA112669C2 (uk) 2016-10-10
MX2014010005A (es) 2015-03-09
GEP20186824B (en) 2018-02-26
US9682147B2 (en) 2017-06-20
NZ627861A (en) 2016-02-26
JP6231499B2 (ja) 2017-11-15
EP2816998A1 (en) 2014-12-31
CN104220048A (zh) 2014-12-17
WO2013124415A1 (en) 2013-08-29
EP2630952A1 (en) 2013-08-28

Similar Documents

Publication Publication Date Title
EA201400869A1 (ru) Масляная дисперсия, способ её получения, упаковка и применение борной кислоты в качестве стимулятора консервации масляной дисперсии
MX362655B (es) Composiciones cosmeticas.
UY34811A (es) Compuestos y composiciones para inhibir la actividad de la abl1, abl2 y bcr-abl1
EA201490458A1 (ru) Способ получения тернесита
IN2015DN01951A (ru)
EA201791321A1 (ru) Составы ингибитора lfa-1
MX2014004464A (es) Insecticida líquido que incluye tierra de diatomeas.
EA201591433A1 (ru) Офтальмологические составы
EA201590041A1 (ru) Твердая форма холиновой соли вемурафениба
BR112015012081A2 (pt) tratamento de café solúvel
WO2013162933A3 (en) Active halogen antimicrobial composition and method of use
PH12016501902A1 (en) Composition in the form of an oil-in-water emulsion comprising ground white or yellow mustard seed
MY189487A (en) Fabric softener compositions
EA201591434A1 (ru) Способ обеспечения глазной нейропротекции
EA201291354A1 (ru) Новое применение диатомитовой земли в фармацевтической промышленности
MX375205B (es) Relleno estable al horneado que contiene micropartículas.
GB2514741A (en) Composition for use as a paint binder
BR112015031820A2 (pt) composto, composição farmacêutica, intermediário, processo para a preparação de um composto e métodos
WO2014201034A3 (en) Treatment for polyomavirus infection
CA2911044C (fr) Procede de stabilisation d'une composition contenant au moins un produit de deshydratation interne d'un sucre hydrogene, composition obtenue et ses utilisations
MX363828B (es) 3-metil-benzofuran-5-ol y su uso en composiciones de perfume.
MX2014005455A (es) Dietil-metil-hexahidro-isobenzofuranos novedosos y su uso en las composiciones de perfume.
MX364401B (es) Dispersiones acuosas de amidas grasas.
EA201390435A1 (ru) Способ выпрямления волос
MX373879B (es) Emulsión de propofol para administración parenteral.