EA201401045A1 - Соединения для лечения заболеваний, связанных с ишемией-реперфузией - Google Patents

Соединения для лечения заболеваний, связанных с ишемией-реперфузией

Info

Publication number
EA201401045A1
EA201401045A1 EA201401045A EA201401045A EA201401045A1 EA 201401045 A1 EA201401045 A1 EA 201401045A1 EA 201401045 A EA201401045 A EA 201401045A EA 201401045 A EA201401045 A EA 201401045A EA 201401045 A1 EA201401045 A1 EA 201401045A1
Authority
EA
Eurasian Patent Office
Prior art keywords
reperfusion
ischemia
treatment
connections
diseases associated
Prior art date
Application number
EA201401045A
Other languages
English (en)
Other versions
EA033160B1 (ru
Inventor
Антонио Гуарна
Федерико Коццолино
Original Assignee
Минерва Патентс С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Минерва Патентс С.А. filed Critical Минерва Патентс С.А.
Publication of EA201401045A1 publication Critical patent/EA201401045A1/ru
Publication of EA033160B1 publication Critical patent/EA033160B1/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/886Streptomyces

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • External Artificial Organs (AREA)

Abstract

Изобретение относится к соединениям формулы (I), применимым при лечении патологий, связанных с ишемией-реперфузией.
EA201401045A 2012-03-21 2013-03-20 Соединения для лечения заболеваний, связанных с ишемией-реперфузией EA033160B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000062A ITFI20120062A1 (it) 2012-03-21 2012-03-21 Componenti per il trattamento di malattie correlate a ischemia-riperfusione.
PCT/IB2013/052205 WO2013140348A1 (en) 2012-03-21 2013-03-20 Compounds for the treatment of ischemia-reperfusion- related diseases

Publications (2)

Publication Number Publication Date
EA201401045A1 true EA201401045A1 (ru) 2015-03-31
EA033160B1 EA033160B1 (ru) 2019-09-30

Family

ID=46147570

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201401045A EA033160B1 (ru) 2012-03-21 2013-03-20 Соединения для лечения заболеваний, связанных с ишемией-реперфузией

Country Status (24)

Country Link
US (2) US9932352B2 (ru)
EP (1) EP2855487B1 (ru)
JP (2) JP6382791B2 (ru)
KR (2) KR20150014910A (ru)
CN (1) CN104395321B (ru)
AU (2) AU2013237021B2 (ru)
CA (1) CA2907652C (ru)
CY (1) CY1118282T1 (ru)
DK (1) DK2855487T3 (ru)
EA (1) EA033160B1 (ru)
ES (1) ES2601384T3 (ru)
HR (1) HRP20161436T1 (ru)
HU (1) HUE031535T2 (ru)
IL (1) IL234796B (ru)
IN (1) IN2014CH07744A (ru)
IT (1) ITFI20120062A1 (ru)
LT (1) LT2855487T (ru)
ME (1) ME02553B (ru)
PL (1) PL2855487T3 (ru)
PT (1) PT2855487T (ru)
RS (1) RS55337B1 (ru)
SI (1) SI2855487T1 (ru)
SM (2) SMT201700055T1 (ru)
WO (1) WO2013140348A1 (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10531655B2 (en) 2011-12-02 2020-01-14 The Regents Of The University Of California Reperfusion protection solution and uses thereof
IT202000008125A1 (it) * 2020-04-16 2021-10-16 Minerva Srl Acidi carbossilici 3-aza-biciclo[3.2.1]ottani e loro derivati per l’uso nel trattamento di infiammazioni
IT202200016614A1 (it) 2022-08-04 2024-02-04 Mimetech S R L Udonitrectag e sue formulazioni ad uso topico per l’uso nel trattamento di patologie dermatologiche

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR75910B (ru) 1981-04-21 1984-08-02 Delalande Sa
DE60042585D1 (de) 2000-02-29 2009-09-03 Univ Firenze 3-Aza-6,8-dioxabicycloÄ3.2.1Üoctane und Analoga sowie diese enthaltende kombinatorische Bibliotheken
ITFI20020107A1 (it) * 2002-06-19 2003-12-19 Antonio Guarna Composizioni farmaceutiche atte all'uso nel trattamento di patologie correlate all'azione di neutrofine e composti attivi in esse contenuti
AP2005003196A0 (en) * 2002-07-18 2005-03-31 Pfizer Prod Inc Bicyclic piperidine derivatives as antagonists of the CCR1 chemokine receptor.
WO2006015183A2 (en) * 2004-07-30 2006-02-09 Axonyx, Inc. Pharmaceutical compositions for treating disorders of the skin
ES2380613T3 (es) * 2008-11-25 2012-05-16 Universita' Degli Studi Di Firenze Inhibidores peptidomiméticos bicíclicos de aspartil-proteasas para el tratamiento de enfermedades infecciosas

Also Published As

Publication number Publication date
JP2015514069A (ja) 2015-05-18
KR20150014910A (ko) 2015-02-09
SMT201700055B (it) 2017-03-08
LT2855487T (lt) 2016-11-25
ES2601384T3 (es) 2017-02-15
EP2855487A1 (en) 2015-04-08
EP2855487B1 (en) 2016-08-03
HRP20161436T1 (hr) 2017-01-13
IL234796B (en) 2018-02-28
US20150080388A1 (en) 2015-03-19
US20180155363A1 (en) 2018-06-07
AU2017265037A1 (en) 2017-12-07
EA033160B1 (ru) 2019-09-30
US9932352B2 (en) 2018-04-03
JP2018168173A (ja) 2018-11-01
SMT201700055T1 (it) 2017-03-08
CN104395321B (zh) 2017-05-03
CA2907652A1 (en) 2013-09-26
KR20200049912A (ko) 2020-05-08
DK2855487T3 (en) 2016-12-05
AU2013237021B2 (en) 2017-08-24
ITFI20120062A1 (it) 2013-09-22
HUE031535T2 (en) 2017-07-28
CA2907652C (en) 2021-03-16
PL2855487T3 (pl) 2017-02-28
IN2014CH07744A (ru) 2016-07-01
CN104395321A (zh) 2015-03-04
ME02553B (me) 2017-02-20
PT2855487T (pt) 2016-12-20
RS55337B1 (sr) 2017-03-31
AU2017265037B2 (en) 2018-03-15
JP6382791B2 (ja) 2018-08-29
CY1118282T1 (el) 2017-06-28
WO2013140348A1 (en) 2013-09-26
AU2013237021A1 (en) 2014-11-13
SI2855487T1 (sl) 2017-05-31
KR102181346B1 (ko) 2020-11-23

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