EA202192541A1 - Фармацевтическая композиция для местного применения в виде водного геля, содержащая, по меньшей мере, амитриптилин - Google Patents

Фармацевтическая композиция для местного применения в виде водного геля, содержащая, по меньшей мере, амитриптилин

Info

Publication number
EA202192541A1
EA202192541A1 EA202192541A EA202192541A EA202192541A1 EA 202192541 A1 EA202192541 A1 EA 202192541A1 EA 202192541 A EA202192541 A EA 202192541A EA 202192541 A EA202192541 A EA 202192541A EA 202192541 A1 EA202192541 A1 EA 202192541A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pharmaceutical composition
amitriptiline
local application
water gel
water
Prior art date
Application number
EA202192541A
Other languages
English (en)
Inventor
Паола Принсипе Николас
Фредерик Лаллеман
Стефан Тиролуа
Original Assignee
Альготерапьютикс
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Альготерапьютикс filed Critical Альготерапьютикс
Publication of EA202192541A1 publication Critical patent/EA202192541A1/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Изобретение относится к топической фармацевтической композиции в виде водного геля, включающей, по меньшей мере, амитриптилин и/или одну из его фармацевтически приемлемых солей, в содержании от 10 до 30 вес.% от полного веса композиции, и воду.
EA202192541A 2020-04-06 2021-03-31 Фармацевтическая композиция для местного применения в виде водного геля, содержащая, по меньшей мере, амитриптилин EA202192541A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR2003425A FR3108841B1 (fr) 2020-04-06 2020-04-06 Composition pharmaceutique topique sous forme de gel aqueux comprenant au moins de l’amitriptyline
PCT/EP2021/058518 WO2021204634A1 (fr) 2020-04-06 2021-03-31 Composition pharmaceutique topique sous forme de gel aqueux comprenant au moins de l'amitriptyline

Publications (1)

Publication Number Publication Date
EA202192541A1 true EA202192541A1 (ru) 2021-11-26

Family

ID=71894918

Family Applications (1)

Application Number Title Priority Date Filing Date
EA202192541A EA202192541A1 (ru) 2020-04-06 2021-03-31 Фармацевтическая композиция для местного применения в виде водного геля, содержащая, по меньшей мере, амитриптилин

Country Status (14)

Country Link
US (3) US20220304949A1 (ru)
EP (1) EP4106726B1 (ru)
JP (1) JP7295273B2 (ru)
KR (1) KR20210153085A (ru)
CN (1) CN113966212A (ru)
AU (1) AU2021229214B2 (ru)
BR (1) BR112021022564A2 (ru)
CA (1) CA3130171C (ru)
EA (1) EA202192541A1 (ru)
ES (1) ES3045060T3 (ru)
FR (1) FR3108841B1 (ru)
IL (1) IL286390A (ru)
MX (1) MX2021011572A (ru)
WO (1) WO2021204634A1 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3108841B1 (fr) 2020-04-06 2023-11-03 Algotherapeutix Composition pharmaceutique topique sous forme de gel aqueux comprenant au moins de l’amitriptyline
CN120585733A (zh) * 2025-06-18 2025-09-05 兰州大学第一医院 一种阿米替林凝胶及其制备方法和应用

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GB9422571D0 (en) * 1994-11-09 1995-01-04 Whitehall Lab Ltd Haemorrihoidal compositions and method of use
SK20012000A3 (sk) 1998-06-29 2001-08-06 Pharmaceuticals Applications Asociates, Llc Transdermálny prostriedok na zmiernenie bolesti
KR100452972B1 (ko) * 2000-05-16 2004-10-14 주식회사 삼양사 경피투여용 하이드로젤 조성물
CA2315815A1 (en) * 2000-07-19 2002-01-19 Peter R. Ford Topical pain relief composition and carrier
US6638981B2 (en) 2001-08-17 2003-10-28 Epicept Corporation Topical compositions and methods for treating pain
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FR3108841B1 (fr) 2020-04-06 2023-11-03 Algotherapeutix Composition pharmaceutique topique sous forme de gel aqueux comprenant au moins de l’amitriptyline
FR3120787B1 (fr) 2021-03-19 2024-04-26 Algotherapeutix Composition pharmaceutique topique comprenant de l’amitriptyline et une phase aqueuse alcaline
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FR3127689B1 (fr) 2021-10-01 2024-10-04 Algotherapeutix Composition pharmaceutique topique sous forme de gel comprenant au moins de l’amitriptyline pour son utilisation dans le traitement des douleurs neuropathiques du membre fantôme

Also Published As

Publication number Publication date
FR3108841A1 (fr) 2021-10-08
JP2022531708A (ja) 2022-07-08
IL286390A (en) 2021-12-01
EP4106726A1 (fr) 2022-12-28
KR20210153085A (ko) 2021-12-16
CA3130171C (fr) 2024-05-21
US20240277630A1 (en) 2024-08-22
ES3045060T3 (en) 2025-11-27
CA3130171A1 (fr) 2021-10-06
WO2021204634A1 (fr) 2021-10-14
MX2021011572A (es) 2022-01-24
BR112021022564A2 (pt) 2022-10-11
AU2021229214A1 (en) 2021-10-21
US12150920B2 (en) 2024-11-26
FR3108841B1 (fr) 2023-11-03
EP4106726C0 (fr) 2025-09-03
CN113966212A (zh) 2022-01-21
US12156854B2 (en) 2024-12-03
AU2021229214B2 (en) 2023-04-13
US20220304949A1 (en) 2022-09-29
JP7295273B2 (ja) 2023-06-20
EP4106726B1 (fr) 2025-09-03
US20240293341A1 (en) 2024-09-05

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