ECSP003527A - Antagonistas del receptor de il - 8 v - Google Patents

Antagonistas del receptor de il - 8 v

Info

Publication number
ECSP003527A
ECSP003527A EC2000003527A ECSP003527A ECSP003527A EC SP003527 A ECSP003527 A EC SP003527A EC 2000003527 A EC2000003527 A EC 2000003527A EC SP003527 A ECSP003527 A EC SP003527A EC SP003527 A ECSP003527 A EC SP003527A
Authority
EC
Ecuador
Prior art keywords
receiver antagonists
antagonists
receiver
chemokine
interleukin
Prior art date
Application number
EC2000003527A
Other languages
English (en)
Inventor
Katherine L Widdowson
John G Gleason
Gregory M Benson
Deborah L Bryan
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of ECSP003527A publication Critical patent/ECSP003527A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Biotechnology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Esta invención se refiere a nuevos compuestos de la fórmula (I), y a composiciones de los mismos, útiles en el tratamiento de enfermedades mediadas por la quimioquina interleuquina-8(IL-8)
EC2000003527A 1999-06-16 2000-06-14 Antagonistas del receptor de il - 8 v ECSP003527A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13967799P 1999-06-16 1999-06-16

Publications (1)

Publication Number Publication Date
ECSP003527A true ECSP003527A (es) 2002-01-25

Family

ID=22487800

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2000003527A ECSP003527A (es) 1999-06-16 2000-06-14 Antagonistas del receptor de il - 8 v

Country Status (9)

Country Link
EP (1) EP1185270A4 (es)
JP (1) JP2003501472A (es)
AU (1) AU5748300A (es)
CO (1) CO5190712A1 (es)
EC (1) ECSP003527A (es)
HK (1) HK1044475A1 (es)
PE (1) PE20010321A1 (es)
UY (1) UY26207A1 (es)
WO (1) WO2000076517A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6642215B2 (en) * 2001-05-24 2003-11-04 Leo Pharma A/S Method of modulating NF-kB activity
WO2005113534A2 (en) 2004-05-12 2005-12-01 Schering Corporation Cxcr1 and cxcr2 chemokine antagonists
EP3355876A2 (en) * 2015-09-30 2018-08-08 Instituto de Medicina Molecular Methods for attenuating parasite virulence

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2928485A1 (de) * 1979-07-14 1981-01-29 Bayer Ag Verwendung von harnstoffderivaten als arzneimittel bei der behandlung von fettstoffwechselstoerungen
ATE98223T1 (de) * 1988-03-30 1993-12-15 Warner Lambert Co N-(((2,6-disubstituierte)phenyl>n'- arylalkyl> harnstoffe als antihypercholesterolemische und antiatherosclerotische mittel.
US5780483A (en) * 1995-02-17 1998-07-14 Smithkline Beecham Corporation IL-8 receptor antagonists
US6335352B1 (en) * 1996-08-15 2002-01-01 Smithkline Beecham Corporation IL-8 receptor antagonists

Also Published As

Publication number Publication date
JP2003501472A (ja) 2003-01-14
HK1044475A1 (zh) 2002-10-25
EP1185270A4 (en) 2004-02-11
EP1185270A1 (en) 2002-03-13
AU5748300A (en) 2001-01-02
CO5190712A1 (es) 2002-08-29
UY26207A1 (es) 2000-12-29
PE20010321A1 (es) 2001-05-18
WO2000076517A1 (en) 2000-12-21

Similar Documents

Publication Publication Date Title
BR0313109A (pt) Ciclobuteno-1,2-dionas 3,4-dissubstituìdas como ligandos de receptor de quimiocina de cxc
CY1106514T1 (el) Ανταγωνιστες υποδοχεων il-8
EA200300717A1 (ru) Гетероциклилиндазольные и -азаиндазольные соединения в качестве 5-гидрокситриптамин-6-лигандов
ATE419845T1 (de) Il-8-rezeptor-antagonisten
CR8475A (es) Fenilalanina-amidas sustituidas por benzoilo
BG66084B1 (bg) Циклопентаноиндоли, състави,съдържащи такива съединения и използването им
TR199900318T2 (xx) IL-8 resept�r antagonistleri.
DE60129154D1 (de) Neuartige verbindungen
UY26601A1 (es) Antagonistas de los receptores de il-8
AR024350A1 (es) Antagonistas de los receptores de il-8
AP1548A (en) Il-8 Receptor Antagonists.
BR0010843A (pt) Antagonistas de receptores de il-8
MY143477A (en) Il-8 receptor antagonists
AP2002002606A0 (en) INTERLEUKIN 8 RECEPTOR ANTAGONISTS
ECSP003529A (es) Antagonistas del receptor de il - 8 vii
UY26207A1 (es) Antagonistas de los receptores de la il-8.
UY26209A1 (es) Antagonistas de los receptores de la il-8.
BR0010863A (pt) Antagonistas de receptores de il-8
WO2001068033A3 (en) Il-8 receptor antagonists
BR0214613A (pt) N-ureìdo-piperidinas como antagonistas viii para receptor de ccr-3
BR9815951A (pt) Antagonistas do receptor de il-8
UY26206A1 (es) Antagonistas del receptor de il-8.
PE20001466A1 (es) Nuevas 3-fenoxi- y 3-fenilalquiloxi-2-fenil-propilaminas sustituidas como bloqueadores del canal de sodio
WO2001068570A3 (en) Il-8 receptor antagonists
PA8607401A1 (es) 3-nitro-piriazolo[1,5a]pirimidinas 7-sustituidas y composiciones y metodos relacionados