ECSP003743A - Profarmacos de higromicina a - Google Patents
Profarmacos de higromicina aInfo
- Publication number
- ECSP003743A ECSP003743A EC2000003743A ECSP003743A ECSP003743A EC SP003743 A ECSP003743 A EC SP003743A EC 2000003743 A EC2000003743 A EC 2000003743A EC SP003743 A ECSP003743 A EC SP003743A EC SP003743 A ECSP003743 A EC SP003743A
- Authority
- EC
- Ecuador
- Prior art keywords
- compounds
- formula
- propharms
- hygromycin
- infections
- Prior art date
Links
- YQYJSBFKSSDGFO-UHFFFAOYSA-N Epihygromycin Natural products OC1C(O)C(C(=O)C)OC1OC(C(=C1)O)=CC=C1C=C(C)C(=O)NC1C(O)C(O)C2OCOC2C1O YQYJSBFKSSDGFO-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 208000035143 Bacterial infection Diseases 0.000 abstract 2
- 206010037075 Protozoal infections Diseases 0.000 abstract 2
- 230000001580 bacterial effect Effects 0.000 abstract 2
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 2
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000003904 antiprotozoal agent Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Esta invención se refiere a compuestos de fórmula (gráfico), y a sales y solvatos farmacéuticamente aceptables de estos, siendo a,b,X, Y, Z, R1, R2 y R3 como se han definido en la descripción adjunta. Los compuestos de fórmula I son agentes antibacterianos y antiprotozoarios que pueden utilizarse para tratar infecciones bacterianas y protozoarias y enfermedades relacionadas con dichas infecciones. La invención se refiere también a composiciones farmacéuticas que contienen los compuestos de fórmula I y a procedimientos para tratar infecciones bacterianas y protozoarias mediante la administración de los compuestos de fórmula I.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16272299P | 1999-10-29 | 1999-10-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP003743A true ECSP003743A (es) | 2002-05-23 |
Family
ID=22586880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2000003743A ECSP003743A (es) | 1999-10-29 | 2000-10-27 | Profarmacos de higromicina a |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US6492342B1 (es) |
| EP (1) | EP1224194A1 (es) |
| JP (1) | JP2003512472A (es) |
| KR (1) | KR20020043255A (es) |
| CN (1) | CN1382149A (es) |
| AP (1) | AP2002002492A0 (es) |
| AR (1) | AR026285A1 (es) |
| AU (1) | AU7307900A (es) |
| BG (1) | BG106635A (es) |
| BR (1) | BR0015156A (es) |
| CA (1) | CA2389019A1 (es) |
| CO (1) | CO5261547A1 (es) |
| CZ (1) | CZ20021347A3 (es) |
| EA (1) | EA200200413A1 (es) |
| EC (1) | ECSP003743A (es) |
| EE (1) | EE200200226A (es) |
| GT (1) | GT200000178A (es) |
| HK (1) | HK1049844A1 (es) |
| HU (1) | HUP0203223A2 (es) |
| IL (1) | IL148580A0 (es) |
| IS (1) | IS6312A (es) |
| MA (1) | MA26839A1 (es) |
| MX (1) | MXPA02004359A (es) |
| NO (1) | NO20021822D0 (es) |
| OA (1) | OA12079A (es) |
| PE (1) | PE20010757A1 (es) |
| PL (1) | PL357080A1 (es) |
| SK (1) | SK5322002A3 (es) |
| SV (1) | SV2002000210A (es) |
| TN (1) | TNSN00209A1 (es) |
| TR (1) | TR200201143T2 (es) |
| WO (1) | WO2001030793A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020041179A1 (en) * | 2018-08-20 | 2020-02-27 | Northeastern University | Hygromycin a compounds and methods of treating spirochete diseases |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3393189B2 (ja) * | 1998-12-02 | 2003-04-07 | ファイザー・プロダクツ・インク | 抗菌薬としてのハイグロマイシンａ誘導体 |
-
2000
- 2000-09-28 BR BR0015156-4A patent/BR0015156A/pt not_active IP Right Cessation
- 2000-09-28 SK SK532-2002A patent/SK5322002A3/sk unknown
- 2000-09-28 AU AU73079/00A patent/AU7307900A/en not_active Abandoned
- 2000-09-28 HK HK03101876.4A patent/HK1049844A1/zh unknown
- 2000-09-28 CZ CZ20021347A patent/CZ20021347A3/cs unknown
- 2000-09-28 AP APAP/P/2002/002492A patent/AP2002002492A0/en unknown
- 2000-09-28 EP EP00960929A patent/EP1224194A1/en not_active Withdrawn
- 2000-09-28 EA EA200200413A patent/EA200200413A1/ru unknown
- 2000-09-28 JP JP2001533144A patent/JP2003512472A/ja not_active Withdrawn
- 2000-09-28 OA OA1200200127A patent/OA12079A/en unknown
- 2000-09-28 CN CN00814799A patent/CN1382149A/zh active Pending
- 2000-09-28 KR KR1020027005467A patent/KR20020043255A/ko not_active Ceased
- 2000-09-28 WO PCT/IB2000/001390 patent/WO2001030793A1/en not_active Ceased
- 2000-09-28 MX MXPA02004359A patent/MXPA02004359A/es active IP Right Grant
- 2000-09-28 IL IL14858000A patent/IL148580A0/xx unknown
- 2000-09-28 TR TR2002/01143T patent/TR200201143T2/xx unknown
- 2000-09-28 PL PL00357080A patent/PL357080A1/xx not_active Application Discontinuation
- 2000-09-28 HU HU0203223A patent/HUP0203223A2/hu unknown
- 2000-09-28 EE EEP200200226A patent/EE200200226A/xx unknown
- 2000-09-28 CA CA002389019A patent/CA2389019A1/en not_active Abandoned
- 2000-10-16 GT GT200000178A patent/GT200000178A/es unknown
- 2000-10-25 PE PE2000001141A patent/PE20010757A1/es not_active Application Discontinuation
- 2000-10-27 EC EC2000003743A patent/ECSP003743A/es unknown
- 2000-10-27 SV SV2000000210A patent/SV2002000210A/es unknown
- 2000-10-27 US US09/698,399 patent/US6492342B1/en not_active Expired - Fee Related
- 2000-10-27 AR ARP000105699A patent/AR026285A1/es not_active Application Discontinuation
- 2000-10-27 CO CO00082085A patent/CO5261547A1/es not_active Application Discontinuation
- 2000-10-27 TN TNTNSN00209A patent/TNSN00209A1/fr unknown
-
2002
- 2002-03-19 IS IS6312A patent/IS6312A/is unknown
- 2002-04-18 NO NO20021822A patent/NO20021822D0/no unknown
- 2002-04-22 MA MA26614A patent/MA26839A1/fr unknown
- 2002-04-23 BG BG106635A patent/BG106635A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SK5322002A3 (en) | 2003-01-09 |
| BG106635A (en) | 2002-12-29 |
| CZ20021347A3 (cs) | 2002-11-13 |
| PE20010757A1 (es) | 2001-07-25 |
| SV2002000210A (es) | 2002-06-07 |
| BR0015156A (pt) | 2002-07-16 |
| WO2001030793A1 (en) | 2001-05-03 |
| MA26839A1 (fr) | 2004-12-20 |
| KR20020043255A (ko) | 2002-06-08 |
| TR200201143T2 (tr) | 2002-08-21 |
| EP1224194A1 (en) | 2002-07-24 |
| EA200200413A1 (ru) | 2002-10-31 |
| CN1382149A (zh) | 2002-11-27 |
| EE200200226A (et) | 2003-06-16 |
| OA12079A (en) | 2006-05-04 |
| NO20021822L (no) | 2002-04-18 |
| HUP0203223A2 (en) | 2003-02-28 |
| AP2002002492A0 (en) | 2002-06-30 |
| AU7307900A (en) | 2001-05-08 |
| JP2003512472A (ja) | 2003-04-02 |
| MXPA02004359A (es) | 2002-11-07 |
| US6492342B1 (en) | 2002-12-10 |
| IS6312A (is) | 2002-03-19 |
| AR026285A1 (es) | 2003-02-05 |
| HK1049844A1 (zh) | 2003-05-30 |
| TNSN00209A1 (fr) | 2005-11-10 |
| NO20021822D0 (no) | 2002-04-18 |
| GT200000178A (es) | 2002-04-09 |
| PL357080A1 (en) | 2004-07-12 |
| IL148580A0 (en) | 2002-09-12 |
| CO5261547A1 (es) | 2003-03-31 |
| CA2389019A1 (en) | 2001-05-03 |
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