ECSP003836A - Composicion estable para dosis oral de liberacion extendida - Google Patents
Composicion estable para dosis oral de liberacion extendidaInfo
- Publication number
- ECSP003836A ECSP003836A EC2000003836A ECSP003836A ECSP003836A EC SP003836 A ECSP003836 A EC SP003836A EC 2000003836 A EC2000003836 A EC 2000003836A EC SP003836 A ECSP003836 A EC SP003836A EC SP003836 A ECSP003836 A EC SP003836A
- Authority
- EC
- Ecuador
- Prior art keywords
- hours
- extended release
- pseudoephedrine
- stable composition
- composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Toxicology (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Toys (AREA)
- Cosmetics (AREA)
Abstract
Se describe una composición para dosis oral sólida de liberación extendida revestida con una película que contiene un descongestivo nasal, pseudoefedrina, o su sal por ejemplo, sulfato de pseudoefedrina en un núcleo efectivo como proporcionar una concentración en plasma máxima geométrica de pseudoefedrina entre alrededor de 345 ng/ml en un tiempo entre alrededor de 7,60 horas y alrededor de 8,40 horas y que tiene dos o tres revestimientos de película sobre el núcleo, el segundo contiene una cantidad de antihistamina, no sedativa, desloratadina, efectiva como para proporcionar una concentración en plasma máximo geométrica de desloratadina entre alrededor de 2,15 ng/ml y alrededor de 2,45 ng/ml en un tiempo entre alrededor de 4,0 horas y alrededor de 4,5 horas, y el uso de la composición para tratar pacientes que muestran signos y síntomas asociadas con las condiciones alérgicas y/o inflamatorias de la piel y de las vías aéreas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17283699P | 1999-12-20 | 1999-12-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP003836A true ECSP003836A (es) | 2002-02-25 |
Family
ID=22629437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2000003836A ECSP003836A (es) | 1999-12-20 | 2000-12-20 | Composicion estable para dosis oral de liberacion extendida |
Country Status (37)
| Country | Link |
|---|---|
| US (2) | US6979463B2 (es) |
| EP (2) | EP2196195A3 (es) |
| JP (3) | JP5042403B2 (es) |
| KR (2) | KR100936572B1 (es) |
| CN (3) | CN1679569A (es) |
| AR (1) | AR027033A1 (es) |
| AT (1) | ATE463240T1 (es) |
| AU (4) | AU2277101A (es) |
| BR (1) | BR0006403A (es) |
| CA (1) | CA2329217C (es) |
| CO (1) | CO5251435A1 (es) |
| CY (1) | CY1110693T1 (es) |
| CZ (1) | CZ302860B6 (es) |
| DE (1) | DE60044117D1 (es) |
| DK (1) | DK1112738T3 (es) |
| EC (1) | ECSP003836A (es) |
| EG (1) | EG23759A (es) |
| ES (1) | ES2341751T3 (es) |
| HU (1) | HUP0004988A3 (es) |
| ID (1) | ID28675A (es) |
| IL (1) | IL140450A (es) |
| MX (1) | MXPA00013037A (es) |
| MY (1) | MY130773A (es) |
| NO (1) | NO331645B1 (es) |
| NZ (1) | NZ509028A (es) |
| PE (1) | PE20010982A1 (es) |
| PL (1) | PL211573B1 (es) |
| PT (1) | PT1112738E (es) |
| RU (2) | RU2303440C2 (es) |
| SA (2) | SA01210741B1 (es) |
| SG (1) | SG109438A1 (es) |
| SI (1) | SI1112738T1 (es) |
| SK (1) | SK287684B6 (es) |
| TR (1) | TR200003787A2 (es) |
| TW (1) | TWI225414B (es) |
| WO (1) | WO2001045668A2 (es) |
| ZA (1) | ZA200007715B (es) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001045668A2 (en) | 1999-12-20 | 2001-06-28 | Schering Corporation | Stable extended release oral dosage composition comprising pseudoephedrine and desloratadine |
| AU2276801A (en) | 1999-12-20 | 2001-07-03 | Schering Corporation | Extended release oral dosage composition |
| US7405223B2 (en) | 2000-02-03 | 2008-07-29 | Schering Corporation | Treating allergic and inflammatory conditions |
| US20030070584A1 (en) | 2001-05-15 | 2003-04-17 | Cynthia Gulian | Dip coating compositions containing cellulose ethers |
| CN1518448A (zh) * | 2001-06-20 | 2004-08-04 | ���鹫˾ | 用于治疗鼻充血和鼻塞的抗组胺剂 |
| US8309118B2 (en) | 2001-09-28 | 2012-11-13 | Mcneil-Ppc, Inc. | Film forming compositions containing sucralose |
| MXPA04008100A (es) * | 2002-02-21 | 2005-06-17 | Biovail Lab Int Srl | Formulaciones de liberacion modificada de al menos una forma de tramadol. |
| US8323692B2 (en) | 2002-02-21 | 2012-12-04 | Valeant International Bermuda | Controlled release dosage forms |
| ATE352305T1 (de) * | 2003-03-12 | 2007-02-15 | Teva Pharma | Stabile pharmazeutische zusammensetzungen mit desloratadine |
| US20050013863A1 (en) | 2003-07-18 | 2005-01-20 | Depomed, Inc., A Corporation Of The State Of California | Dual drug dosage forms with improved separation of drugs |
| EP1700591A4 (en) * | 2003-12-01 | 2011-08-03 | Takeda Pharmaceutical | METHOD FOR THE TREATMENT OF A SOLID PHARMACEUTICAL PREPARATION BEFORE PRINTING AND PRESTIGIOUS SOLENOID PREPARATION TREATED BEFORE PRINTING |
| WO2006047427A1 (en) * | 2004-10-25 | 2006-05-04 | Schering Corporation | M1 and/or m3 receptor antagonists in combination with other actives for treating respiratory disorders |
| US20060252831A1 (en) * | 2005-05-06 | 2006-11-09 | Christopher Offen | Method for the treatment of magnesium and potassium deficiencies |
| US20060252830A1 (en) * | 2005-05-06 | 2006-11-09 | Brandon Stephen F | Method for the treatment of magnesium and potassium deficiencies |
| US20070014855A1 (en) * | 2005-07-12 | 2007-01-18 | Rahul Gawande S | Stable desloratadine compositions |
| US20070036859A1 (en) * | 2005-08-11 | 2007-02-15 | Perry Ronald L | Sustained release antihistamine and decongestant composition |
| US7827042B2 (en) | 2005-11-30 | 2010-11-02 | The Invention Science Fund I, Inc | Methods and systems related to transmission of nutraceutical associated information |
| US8000981B2 (en) | 2005-11-30 | 2011-08-16 | The Invention Science Fund I, Llc | Methods and systems related to receiving nutraceutical associated information |
| US7927787B2 (en) | 2006-06-28 | 2011-04-19 | The Invention Science Fund I, Llc | Methods and systems for analysis of nutraceutical associated components |
| US10296720B2 (en) | 2005-11-30 | 2019-05-21 | Gearbox Llc | Computational systems and methods related to nutraceuticals |
| US20080210748A1 (en) | 2005-11-30 | 2008-09-04 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware, | Systems and methods for receiving pathogen related information and responding |
| US8340944B2 (en) | 2005-11-30 | 2012-12-25 | The Invention Science Fund I, Llc | Computational and/or control systems and methods related to nutraceutical agent selection and dosing |
| US8297028B2 (en) | 2006-06-14 | 2012-10-30 | The Invention Science Fund I, Llc | Individualized pharmaceutical selection and packaging |
| US7974856B2 (en) | 2005-11-30 | 2011-07-05 | The Invention Science Fund I, Llc | Computational systems and methods related to nutraceuticals |
| FR2894143B1 (fr) * | 2005-12-01 | 2008-05-02 | Pierre Fabre Medicament Sa | Composition a liberation prolongee de l'actif, son procede de preparation et son utilisation. |
| NZ573174A (en) * | 2006-06-01 | 2012-01-12 | Msd Consumer Care Inc | Sustained release pharmaceutical dosage form containing phenylephrine |
| RU2008151945A (ru) * | 2006-06-01 | 2010-07-20 | Шеринг Корпорейшн (US) | Лекарственные формы с пульсирующим высвобождением и фармацевтические композиции фенилэфрина |
| WO2007143163A2 (en) * | 2006-06-01 | 2007-12-13 | Schering Corporation | Pharmaceutical compositions for sustained release of phenyephrine |
| WO2007143158A2 (en) * | 2006-06-01 | 2007-12-13 | Schering-Plough Healthcare Products, Inc. | Sustained release pharmaceutical formulation comprising phenylephrine |
| US20080095843A1 (en) * | 2006-07-11 | 2008-04-24 | Nutalapati Siva R K | Controlled-release formulations |
| CN101848706A (zh) * | 2007-06-01 | 2010-09-29 | 先灵-普劳健康护理产品公司 | 包含底物和含活性成分和聚乙烯醇的包衣的药用组合物 |
| PE20091084A1 (es) * | 2007-12-07 | 2009-07-23 | Schering Plough Healthcare | Formulaciones farmaceuticas de fenilefrina y composiciones para absorcion transmucosal |
| WO2010099508A1 (en) | 2009-02-26 | 2010-09-02 | Theraquest Biosciences, Inc. | Extended release oral pharmaceutical compositions of 3-hydroxy-n-methylmorphinan and method of use |
| WO2010143202A1 (en) * | 2009-06-09 | 2010-12-16 | Sun Pharmaceutical Industries Ltd. | Pharmaceutical composition |
| TR201009396A2 (tr) | 2010-11-11 | 2012-05-21 | Bi̇lgi̇ç Mahmut | Desloratadin granüller |
| DE102016107760B4 (de) * | 2016-04-26 | 2018-09-20 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Essbare Funktionsschichten und Überzüge auf Hybridpolymerbasis für Pharmazie und Lebensmittel |
| US10463656B2 (en) | 2017-01-05 | 2019-11-05 | Iowa State University Research Foundation, Inc. | Methods and compositions for prevention of feedlot bovine respiratory disease |
| CR20230109A (es) | 2020-07-30 | 2023-05-11 | Faes Farma Sa | Sistema de liberación de fármacos descongestivos y bilastina |
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| US100000A (en) | 1870-02-22 | Improved sun-bonnet for horses | ||
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| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US3940485A (en) | 1973-12-12 | 1976-02-24 | Levinson Harold N | Treatment and pre-treatment of dysmetric dyslexia by improving sequential scanning and ocular fixation abilities and therapeutic compounds |
| US4008796A (en) | 1974-03-26 | 1977-02-22 | General Concrete Of Canada Limited | Control method for feeding items on a conveyor |
| GB1548022A (en) | 1976-10-06 | 1979-07-04 | Wyeth John & Brother Ltd | Pharmaceutial dosage forms |
| US4282233B1 (en) | 1980-06-19 | 2000-09-05 | Schering Corp | Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines |
| HU194864B (en) | 1984-02-15 | 1988-03-28 | Schering Corp | Process for production of 8-chlor-6,11-dihydro-11-(4-piperidilidene)-5h-benzo (5,6)-cyclo-hepta (1,2-b) pyridine and its salts |
| US4552899A (en) | 1984-04-09 | 1985-11-12 | Analgesic Associates | Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs |
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| JPS6396126A (ja) * | 1986-10-13 | 1988-04-27 | Taisho Pharmaceut Co Ltd | 安定化組成物 |
| US5089496A (en) * | 1986-10-31 | 1992-02-18 | Schering Corporation | Benzo[5,6]cycloheptapyridine compounds, compositions and method of treating allergies |
| US4777170A (en) | 1987-02-03 | 1988-10-11 | Heinrich William A | Method to prevent and treat the signs and symptoms of motion sickness |
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| US4863931A (en) * | 1988-09-15 | 1989-09-05 | Schering Corporation | Antihistaminic fluoro substituted benzocycloheptapyridines |
| US5019591A (en) * | 1989-02-17 | 1991-05-28 | Pennsylvania Research Corporation | Method for treating retinopathy and other small vessel disorders associated with diabetes |
| US4990535A (en) * | 1989-05-03 | 1991-02-05 | Schering Corporation | Pharmaceutical composition comprising loratadine, ibuprofen and pseudoephedrine |
| IE68935B1 (en) | 1990-06-22 | 1996-07-24 | Schering Corp | Bis-benzo or benzopyrido cyclohepta piperidene piperidylidene and piperazine compounds compositions and methods of use |
| WO1992011034A1 (en) | 1990-12-18 | 1992-07-09 | The Wellcome Foundation Limited | Agents for potentiating the effects of antitumor agents and combating multiple drug resistance |
| MX9202350A (es) | 1991-05-20 | 1992-11-01 | Alza Corp | Composiciones de incrementador de penetracion a la piel que usan monolinoleato de glicerol. |
| YU48263B (sh) * | 1991-06-17 | 1997-09-30 | Byk Gulden Lomberg Chemische Fabrik Gmbh. | Postupak za dobijanje farmaceutskog preparata na bazi pantoprazola |
| US5266331A (en) * | 1991-11-27 | 1993-11-30 | Euroceltique, S.A. | Controlled release oxycodone compositions |
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| US5314697A (en) * | 1992-10-23 | 1994-05-24 | Schering Corporation | Stable extended release oral dosage composition comprising loratadine and pseudoephedrine |
| IT1264517B1 (it) * | 1993-05-31 | 1996-09-24 | Ekita Investments Nv | Compressa farmaceutica atta al rilascio in tempi successivi dei principi attivi in essa veicolati |
| JP2646972B2 (ja) | 1993-11-01 | 1997-08-27 | 日本電気株式会社 | 多ビットメモリ |
| DE4442999A1 (de) | 1994-12-02 | 1996-06-05 | Hexal Pharma Gmbh | Pharmazeutische Zusammensetzung mit einem aktiven Loratidin-Metaboliten |
| US5595997A (en) * | 1994-12-30 | 1997-01-21 | Sepracor Inc. | Methods and compositions for treating allergic rhinitis and other disorders using descarboethoxyloratadine |
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| US6114346A (en) * | 1999-10-22 | 2000-09-05 | Schering Corporation | Treating sleep disorders using desloratadine |
| WO2001045668A2 (en) | 1999-12-20 | 2001-06-28 | Schering Corporation | Stable extended release oral dosage composition comprising pseudoephedrine and desloratadine |
| AU2276801A (en) * | 1999-12-20 | 2001-07-03 | Schering Corporation | Extended release oral dosage composition |
| US7405223B2 (en) * | 2000-02-03 | 2008-07-29 | Schering Corporation | Treating allergic and inflammatory conditions |
| HK1046367A1 (zh) * | 2000-02-03 | 2003-01-10 | Schering Corporation | 治疗过敏和炎症症状 |
| AU5722701A (en) * | 2000-05-19 | 2001-12-03 | Alcon Universal Ltd | Aniline disulfide derivatives for treating allergic diseases |
| US6599913B1 (en) * | 2001-06-29 | 2003-07-29 | Schering Corporation | Treating allergic and inflammatory conditions |
-
2000
- 2000-12-19 WO PCT/US2000/034412 patent/WO2001045668A2/en not_active Ceased
- 2000-12-19 SK SK1967-2000A patent/SK287684B6/sk not_active IP Right Cessation
- 2000-12-19 AU AU22771/01A patent/AU2277101A/en not_active Abandoned
- 2000-12-20 EP EP10159005A patent/EP2196195A3/en not_active Withdrawn
- 2000-12-20 DK DK00311445.1T patent/DK1112738T3/da active
- 2000-12-20 AR ARP000106790A patent/AR027033A1/es not_active Application Discontinuation
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- 2000-12-20 EG EG20001571A patent/EG23759A/xx active
- 2000-12-20 MX MXPA00013037A patent/MXPA00013037A/es active IP Right Grant
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- 2000-12-20 CN CNA2005100713014A patent/CN1679569A/zh active Pending
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- 2000-12-20 KR KR1020000079045A patent/KR100936572B1/ko not_active Expired - Fee Related
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- 2000-12-20 TW TW089127375A patent/TWI225414B/zh not_active IP Right Cessation
- 2000-12-20 NZ NZ509028A patent/NZ509028A/xx not_active IP Right Cessation
- 2000-12-20 RU RU2000131898/15A patent/RU2303440C2/ru not_active IP Right Cessation
- 2000-12-20 CN CN2006100944812A patent/CN101081224B/zh not_active Expired - Fee Related
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- 2000-12-20 PE PE2000001371A patent/PE20010982A1/es not_active Application Discontinuation
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- 2000-12-20 BR BR0006403-3A patent/BR0006403A/pt not_active Application Discontinuation
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2001
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2002
- 2002-06-19 US US10/175,460 patent/US6979463B2/en not_active Expired - Lifetime
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2005
- 2005-08-22 AU AU2005203771A patent/AU2005203771A1/en not_active Abandoned
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2007
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2009
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2010
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2011
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2012
- 2012-08-17 JP JP2012181028A patent/JP2012224642A/ja not_active Withdrawn
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