ECSP034455A - Forma de dosificacion de farmaco activada por hidrogel - Google Patents

Forma de dosificacion de farmaco activada por hidrogel

Info

Publication number
ECSP034455A
ECSP034455A EC2003004455A ECSP034455A ECSP034455A EC SP034455 A ECSP034455 A EC SP034455A EC 2003004455 A EC2003004455 A EC 2003004455A EC SP034455 A ECSP034455 A EC SP034455A EC SP034455 A ECSP034455 A EC SP034455A
Authority
EC
Ecuador
Prior art keywords
core
dosage form
pharmaco
hydrogel
activated
Prior art date
Application number
EC2003004455A
Other languages
English (en)
Inventor
William Jhon Curatolo
Scott Max Herbig
Dwayne Thomas Friesen
Walter C Babcock
Avinash Govind Thombre
Leah Elizabeth Appel
Mark Brian Chidlaw
Ronald Arthur Beyerinck
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ECSP034455A publication Critical patent/ECSP034455A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Una forma de dosificación de liberación controlada comprende un núcleo recubierto, comprendiendo el núcleo una composición que contiene fármaco y una composición hinchable con agua y ocupando cada una regiones separadas dentro del núcleo. El recubrimiento que rodea el núcleo es permeable al agua, insoluble en agua y tiene al menos una abertura de suministro. Se describen una diversidad de configuraciones geométricas.
EC2003004455A 2000-08-09 2003-01-28 Forma de dosificacion de farmaco activada por hidrogel ECSP034455A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US22419900P 2000-08-09 2000-08-09

Publications (1)

Publication Number Publication Date
ECSP034455A true ECSP034455A (es) 2003-03-10

Family

ID=22839665

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2003004455A ECSP034455A (es) 2000-08-09 2003-01-28 Forma de dosificacion de farmaco activada por hidrogel

Country Status (30)

Country Link
US (2) US20030086972A1 (es)
EP (1) EP1326587A2 (es)
JP (1) JP2004505907A (es)
KR (1) KR20030024844A (es)
CN (1) CN1461212A (es)
AP (1) AP2001002237A0 (es)
AU (1) AU2002229141A1 (es)
BG (1) BG107538A (es)
BR (1) BR0113067A (es)
CA (1) CA2418907A1 (es)
DO (1) DOP2001000229A (es)
EA (1) EA200300081A1 (es)
EC (1) ECSP034455A (es)
EE (1) EE200300055A (es)
GT (1) GT200100161A (es)
HR (1) HRP20030082A2 (es)
HU (1) HUP0300722A2 (es)
IL (1) IL154012A0 (es)
IS (1) IS6686A (es)
MA (1) MA26939A1 (es)
MX (1) MXPA03001209A (es)
NO (1) NO20030627L (es)
OA (1) OA12365A (es)
PA (1) PA8524901A1 (es)
PE (1) PE20020307A1 (es)
PL (1) PL360658A1 (es)
SV (1) SV2002000586A (es)
TN (1) TNSN01123A1 (es)
UY (1) UY26876A1 (es)
WO (1) WO2002011702A2 (es)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0957073A1 (en) 1998-05-12 1999-11-17 Schwarz Pharma Ag Novel derivatives of 3,3-diphenylpropylamines
PT1242055E (pt) * 1999-12-23 2008-07-02 Pfizer Prod Inc Forma de dosagem de fármaco baseada em hidrogel
AR030557A1 (es) 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento
WO2002055009A1 (en) 2001-01-12 2002-07-18 Sun Pharmaceutical Industries Limited Spaced drug delivery system
WO2003026626A2 (en) 2001-09-28 2003-04-03 Mcneil-Ppc, Inc. Modified release dosage forms
WO2003096968A2 (en) * 2002-05-15 2003-11-27 Sun Pharmaceutical Industries Limited Oral osmotic controlled drug delivery system
US7785627B2 (en) 2002-09-20 2010-08-31 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US8084058B2 (en) 2002-09-20 2011-12-27 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
AU2003272504A1 (en) * 2002-09-20 2004-04-08 Andrx Labs Llc Multistage formulation containing a biguanide and thiazolidindione derivatives
US7959946B2 (en) 2002-09-20 2011-06-14 Watson Pharmaceuticals, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US9060941B2 (en) 2002-09-20 2015-06-23 Actavis, Inc. Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
US7807197B2 (en) 2002-09-28 2010-10-05 Mcneil-Ppc, Inc. Composite dosage forms having an inlaid portion
NZ538842A (en) * 2002-09-28 2008-03-28 Mcneil Ppc Inc Immediate release dosage form comprising a solid core of density 0.9 g/ml surrounded by a shell that is readily soluble to gastrointestinal fluids
FR2850576B1 (fr) 2003-02-05 2007-03-23 Ethypharm Sa Composition comprenant un melange de principes actifs, et procede de preparation
US20060210633A1 (en) * 2003-04-03 2006-09-21 Sun Pharmaceutical Industries Limited Programmed drug delivery system
DE10315917A1 (de) * 2003-04-08 2004-11-18 Schwarz Pharma Ag Hochreine Basen von 3,3-Diphenylpropylaminmonoestern
AR040157A1 (es) * 2003-06-06 2005-03-16 Rodriguez Julio Cesar Una formulacion en microgranulos para administracion oral en suspension acuosa
MXPA06001506A (es) * 2003-08-04 2006-05-15 Pfizer Prod Inc Formas de dosificacion de inhibidores de la proteina de transferencia de colesteril ester e inhibidores de la hmg-coa reductasa.
US8067029B2 (en) 2004-01-13 2011-11-29 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
US7879354B2 (en) 2004-01-13 2011-02-01 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
WO2006082500A1 (en) * 2005-02-03 2006-08-10 Pfizer Products Inc. Dosage forms providing controlled and immediate release of cholesteryl ester transfer protein inhibitors and immediate release of hmg-coa reductase inhibitors
US20060193912A1 (en) * 2005-02-28 2006-08-31 Penwest Pharmaceuticals Co. Controlled release O-desmethylvenlafaxine formulations
US20080213381A1 (en) * 2005-03-14 2008-09-04 Pharmaceutical Industries Limited Oral Drug Delivery System
WO2006099618A1 (en) * 2005-03-16 2006-09-21 Dr. Reddy's Laboratories Ltd. Delivery system for multiple drugs
US8673352B2 (en) 2005-04-15 2014-03-18 Mcneil-Ppc, Inc. Modified release dosage form
CN100448433C (zh) * 2005-09-21 2009-01-07 广州贝氏药业有限公司 一种克拉霉素肠溶药物组合物
EP2012706A4 (en) * 2006-04-20 2013-02-13 Transport Pharmaceuticals Inc PHARMACEUTICAL FORMULATIONS FOR IONTOPHORETIC METHOTREXATE RELEASE
SA07280459B1 (ar) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
KR20080076382A (ko) * 2007-02-15 2008-08-20 (주)아모레퍼시픽 실로스타졸의 제어방출 제제 및 그 제조방법
BRPI0908114A2 (pt) * 2008-02-15 2015-10-06 Sun Pharma Advanced Res Co Ltd tabuleta oral de liberação controlada
WO2011055269A1 (en) * 2009-11-09 2011-05-12 Pfizer Inc. Delivery carrier
KR101792299B1 (ko) 2010-03-19 2017-10-31 다이이찌 산쿄 가부시키가이샤 항응고제의 용출 개선 방법
TWI578988B (zh) 2011-08-10 2017-04-21 第一三共股份有限公司 含二胺衍生物之醫藥組成物
EP2950822B1 (en) * 2013-01-30 2019-04-24 Daewoong Co., Ltd. Pharmaceutical composition for protecting wounds, providing hemostasis, or preventing adhesion in the gastrointestinal tract
MA41868A (fr) * 2015-04-01 2018-02-06 Spectrum Brands Inc Pastille retard et procédés s'y rapportant
US10350822B1 (en) * 2018-01-09 2019-07-16 Triastek Inc. Dosage forms with desired release profiles and methods of designing and making thereof
CN111867562B (zh) * 2018-03-07 2023-07-07 陈献 不溶性药物的水性制剂
WO2022251620A1 (en) * 2021-05-28 2022-12-01 Amgen Inc. Formulations of apremilast
CN113600179B (zh) * 2021-09-16 2023-07-04 山东博霖环保科技发展有限公司 一种脱硝催化剂及其制备方法
WO2023063381A1 (ja) * 2021-10-14 2023-04-20 静岡県公立大学法人 粉末製剤

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1025765B (it) * 1974-11-18 1978-08-30 Gastaldi Francesco Essiccatore perfezionato a spruzzo
US4187617A (en) * 1978-12-18 1980-02-12 Becker James J Jr Spray dryer
US4327725A (en) * 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
US4449983A (en) * 1982-03-22 1984-05-22 Alza Corporation Simultaneous delivery of two drugs from unit delivery device
US4612008A (en) * 1983-05-11 1986-09-16 Alza Corporation Osmotic device with dual thermodynamic activity
US4624848A (en) * 1984-05-10 1986-11-25 Ciba-Geigy Corporation Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use
US4851232A (en) * 1987-02-13 1989-07-25 Alza Corporation Drug delivery system with means for obtaining desirable in vivo release rate pattern
GB8820353D0 (en) * 1988-08-26 1988-09-28 Staniforth J N Controlled release tablet
US5612059A (en) * 1988-08-30 1997-03-18 Pfizer Inc. Use of asymmetric membranes in delivery devices
US5096716A (en) * 1988-09-01 1992-03-17 Alza Corporation Dosage form for administering calcium antagonist nicardipine
US5030452A (en) * 1989-01-12 1991-07-09 Pfizer Inc. Dispensing devices powered by lyotropic liquid crystals
IL92966A (en) * 1989-01-12 1995-07-31 Pfizer Dispensing devices powered by hydrogel
US5120548A (en) * 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
JPH05178763A (ja) * 1991-02-19 1993-07-20 Nippon Saafuakutanto Kogyo Kk 難溶解性薬物溶解剤組成物
NZ283160A (en) * 1994-05-06 1998-07-28 Pfizer Azithromycin in a controlled release dosage form for treating microbiol infections
US5654005A (en) * 1995-06-07 1997-08-05 Andrx Pharmaceuticals, Inc. Controlled release formulation having a preformed passageway
TW487582B (en) * 1995-08-11 2002-05-21 Nissan Chemical Ind Ltd Method for converting sparingly water-soluble medical substance to amorphous state
SK180499A3 (en) * 1997-07-01 2001-08-06 Pfizer Sertraline salts and sustained-release dosage forms of sertraline
CN1261794A (zh) * 1997-07-01 2000-08-02 辉瑞产品公司 增溶的舍曲林组合物
DE19747261A1 (de) * 1997-10-25 1999-04-29 Bayer Ag Osmotisches Arzneimittelfreisetzungssystem
US6037346A (en) * 1997-10-28 2000-03-14 Vivus, Inc. Local administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction
OA11662A (en) * 1998-10-13 2004-12-08 Pfizer Prod Inc Sertraline oral concentrate.
ATE433318T1 (de) * 1999-02-10 2009-06-15 Pfizer Prod Inc Osmotisches system zur verabreichung von wirkstoffen, die feste amorphe dispersionen enthalten
US6500459B1 (en) * 1999-07-21 2002-12-31 Harinderpal Chhabra Controlled onset and sustained release dosage forms and the preparation thereof
AR028253A1 (es) * 2000-03-16 2003-04-30 Pfizer Prod Inc Inhibidores de la glucogeno fosforilasa
AU2003283688A1 (en) * 2002-12-11 2004-06-30 Pfizer Products Inc. Controlled-release of an active substance into a high fat environment

Also Published As

Publication number Publication date
DOP2001000229A (es) 2002-09-30
HRP20030082A2 (en) 2003-04-30
NO20030627D0 (no) 2003-02-07
WO2002011702A2 (en) 2002-02-14
SV2002000586A (es) 2002-10-24
MA26939A1 (fr) 2004-12-20
PL360658A1 (en) 2004-09-20
AU2002229141A1 (en) 2002-02-18
UY26876A1 (es) 2002-03-22
IL154012A0 (en) 2003-07-31
EP1326587A2 (en) 2003-07-16
TNSN01123A1 (fr) 2005-11-10
WO2002011702A3 (en) 2002-11-28
MXPA03001209A (es) 2003-06-30
GT200100161A (es) 2002-03-22
EA200300081A1 (ru) 2003-08-28
KR20030024844A (ko) 2003-03-26
BR0113067A (pt) 2003-07-01
NO20030627L (no) 2003-04-08
IS6686A (is) 2003-01-16
PA8524901A1 (es) 2002-04-25
BG107538A (bg) 2003-11-28
AP2001002237A0 (en) 2001-09-30
EE200300055A (et) 2004-12-15
OA12365A (en) 2006-05-16
HUP0300722A2 (hu) 2003-11-28
PE20020307A1 (es) 2002-04-23
CN1461212A (zh) 2003-12-10
US20030086972A1 (en) 2003-05-08
JP2004505907A (ja) 2004-02-26
CA2418907A1 (en) 2002-02-14
US20040052845A1 (en) 2004-03-18

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