ECSP034552A - AZA AND POLIAZA-NAFTALENIL CARBOXAMIDES USEFUL AS INHIBITORS OF HIV INTEGRESS - Google Patents

AZA AND POLIAZA-NAFTALENIL CARBOXAMIDES USEFUL AS INHIBITORS OF HIV INTEGRESS

Info

Publication number
ECSP034552A
ECSP034552A ECSP034552A ECSP034552A EC SP034552 A ECSP034552 A EC SP034552A EC SP034552 A ECSP034552 A EC SP034552A EC SP034552 A ECSP034552 A EC SP034552A
Authority
EC
Ecuador
Prior art keywords
inhibitors
hiv
aza
treatment
poliaza
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Neville J Anthony
Melissa Egbertson
John S Wai
Linghang Zhuang
James P Guare
Robert P Gomez
Steven D Young
Mark Embrey
Lekhanh Tran
Jeffrey Y Melamed
Marie Langford
Thorsten E Fisher
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of ECSP034552A publication Critical patent/ECSP034552A/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Se describen derivados de aza y poliaza-neftalenil carboxamida, con inclusión de ciertos derivados de quinolín carboxamida y de naftiridin carboxamida. Estos compuestos son inhibidores de la integrasa del VIH e inhibidores de la replicación del VIH y son útiles en la prevención o el tratamiento del SIDA, como compuestos o sales farmacéuticamente aceptables o como ingredientes en composiciones farmacéuticas, optativamente en combinación con otros agentes antivirales inmunomodulantes, antibióticos o vacunas. También se describen métodos para la prevención el tratamiento y la demora del inicio del SIDA y métodos para la prevención o el tratamiento de la infección por el VIH.Aza and polyaza-nephthalenyl carboxamide derivatives are described, including certain quinoline carboxamide and naphthyridine carboxamide derivatives. These compounds are inhibitors of HIV integrase and inhibitors of HIV replication and are useful in the prevention or treatment of AIDS, as pharmaceutically acceptable compounds or salts or as ingredients in pharmaceutical compositions, optionally in combination with other immunomodulating antiviral agents, antibiotics or vaccines Methods for preventing the treatment and delay of the onset of AIDS and methods for the prevention or treatment of HIV infection are also described.

ECSP034552 2000-10-12 2003-04-11 AZA AND POLIAZA-NAFTALENIL CARBOXAMIDES USEFUL AS INHIBITORS OF HIV INTEGRESS ECSP034552A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23970700P 2000-10-12 2000-10-12

Publications (1)

Publication Number Publication Date
ECSP034552A true ECSP034552A (en) 2003-06-25

Family

ID=34078783

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP034552 ECSP034552A (en) 2000-10-12 2003-04-11 AZA AND POLIAZA-NAFTALENIL CARBOXAMIDES USEFUL AS INHIBITORS OF HIV INTEGRESS

Country Status (3)

Country Link
DO (1) DOP2001000263A (en)
EC (1) ECSP034552A (en)
ZA (1) ZA200302616B (en)

Also Published As

Publication number Publication date
DOP2001000263A (en) 2002-06-15
ZA200302616B (en) 2004-07-15

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