ECSP034768A - Dimetil(1-(1-fenil-ciclohexil)-piperidin-3-ilmetil)-amina sustituida y su uso como analgesico - Google Patents

Dimetil(1-(1-fenil-ciclohexil)-piperidin-3-ilmetil)-amina sustituida y su uso como analgesico

Info

Publication number
ECSP034768A
ECSP034768A EC2003004768A ECSP034768A ECSP034768A EC SP034768 A ECSP034768 A EC SP034768A EC 2003004768 A EC2003004768 A EC 2003004768A EC SP034768 A ECSP034768 A EC SP034768A EC SP034768 A ECSP034768 A EC SP034768A
Authority
EC
Ecuador
Prior art keywords
piperidin
cyclohexyl
phenyl
dimethyl
ilmetile
Prior art date
Application number
EC2003004768A
Other languages
English (en)
Inventor
Michael Sattlegger
Elke Reismueller
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of ECSP034768A publication Critical patent/ECSP034768A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

La invención trata de dimetil-[I-1(fenil-ciclohexil)-piperidin-3-ilmetil-amina sustituida, un procedimiento para su elaboración, un fármaco que contiene estos compuestos y uso de esta sustancia para la elaboración de fármacos.
EC2003004768A 2001-03-14 2003-09-12 Dimetil(1-(1-fenil-ciclohexil)-piperidin-3-ilmetil)-amina sustituida y su uso como analgesico ECSP034768A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10112198A DE10112198A1 (de) 2001-03-14 2001-03-14 Substituierte Dimethyl-[1-(1-phenyl-cyclohexyl)-piperidin-3-ylmethyl]-amine

Publications (1)

Publication Number Publication Date
ECSP034768A true ECSP034768A (es) 2003-10-28

Family

ID=7677392

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2003004768A ECSP034768A (es) 2001-03-14 2003-09-12 Dimetil(1-(1-fenil-ciclohexil)-piperidin-3-ilmetil)-amina sustituida y su uso como analgesico

Country Status (23)

Country Link
US (1) US7049327B2 (es)
EP (1) EP1370529B1 (es)
JP (1) JP2004526726A (es)
KR (1) KR20040012733A (es)
CN (1) CN1496352A (es)
AT (1) ATE315551T1 (es)
BR (1) BR0208243A (es)
CA (1) CA2440758A1 (es)
CZ (1) CZ20032455A3 (es)
DE (2) DE10112198A1 (es)
DK (1) DK1370529T3 (es)
EC (1) ECSP034768A (es)
ES (1) ES2256499T3 (es)
HU (1) HUP0302800A2 (es)
IL (1) IL157893A0 (es)
MX (1) MXPA03007967A (es)
NO (1) NO20034029L (es)
PE (1) PE20020926A1 (es)
PL (1) PL364415A1 (es)
RU (1) RU2003129061A (es)
SK (1) SK11122003A3 (es)
WO (1) WO2002072550A1 (es)
ZA (1) ZA200307964B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105646332B (zh) * 2014-11-09 2018-05-25 复旦大学 氨基甲基哌啶类衍生物及其制备方法和药物用途
WO2018136546A1 (en) 2017-01-17 2018-07-26 Mebias Discovery Llc Substituted 3-dialkylaminomethyl-piperidin-4-yl-benzamides and methods of making and using same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL40064A0 (en) * 1972-08-07 1972-10-29 Univ Tel Aviv Phencyclidine and its derivatives as short-time acting midriatics
US6342511B1 (en) * 1977-06-03 2002-01-29 Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) Phencyclidine derivatives, preparation method and pharmaceutical compositions containing same
US4598153A (en) * 1984-12-19 1986-07-01 The United States Of America As Represented By The Department Of Health And Human Services Metaphit, a specific acylating agent for the [3 H] phencyclidine
US5155212A (en) * 1986-05-21 1992-10-13 Abbott Laboratories Phencyclidine and phencyclidine metabolites assay, tracers, immunogens, antibodies and reagent kit
ES2172595T3 (es) * 1994-09-30 2002-10-01 Novartis Ag Compuestos de 1-acil-4-alifatilaminopiperidina.
ID29137A (id) * 1998-07-27 2001-08-02 Schering Corp Ligan-ligan afinitas tinggi untuk reseptor nosiseptin orl-1
DE10000312A1 (de) * 2000-01-05 2001-07-12 Gruenenthal Gmbh Substituierte Aminomethyl-Phenyl-Cyclohexanderivate

Also Published As

Publication number Publication date
NO20034029L (no) 2003-11-13
HUP0302800A2 (hu) 2003-11-28
IL157893A0 (en) 2004-03-28
DE10112198A1 (de) 2002-09-19
EP1370529B1 (de) 2006-01-11
KR20040012733A (ko) 2004-02-11
CN1496352A (zh) 2004-05-12
JP2004526726A (ja) 2004-09-02
CA2440758A1 (en) 2002-09-19
WO2002072550A1 (de) 2002-09-19
CZ20032455A3 (cs) 2003-12-17
PE20020926A1 (es) 2002-10-26
DK1370529T3 (da) 2006-05-22
RU2003129061A (ru) 2005-04-10
EP1370529A1 (de) 2003-12-17
PL364415A1 (en) 2004-12-13
US7049327B2 (en) 2006-05-23
SK11122003A3 (sk) 2004-01-08
MXPA03007967A (es) 2004-10-15
ZA200307964B (en) 2004-09-14
ATE315551T1 (de) 2006-02-15
BR0208243A (pt) 2004-03-09
NO20034029D0 (no) 2003-09-11
DE50205593D1 (de) 2006-04-06
ES2256499T3 (es) 2006-07-16
US20040127516A1 (en) 2004-07-01

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