ECSP034813A - ARILSULFONAMIDS AS ANTIVIRAL AGENTS - Google Patents

ARILSULFONAMIDS AS ANTIVIRAL AGENTS

Info

Publication number
ECSP034813A
ECSP034813A EC2003004813A ECSP034813A ECSP034813A EC SP034813 A ECSP034813 A EC SP034813A EC 2003004813 A EC2003004813 A EC 2003004813A EC SP034813 A ECSP034813 A EC SP034813A EC SP034813 A ECSP034813 A EC SP034813A
Authority
EC
Ecuador
Prior art keywords
antiviral agents
arilsulfonamids
well
substituents
procedures
Prior art date
Application number
EC2003004813A
Other languages
Spanish (es)
Inventor
Joerg Keldenich
Tobias Wunberg
Juergen Reefschlaeger
Kerstin Henninger
Siegfried Raddatz
Armin Kern
Gunther Schmidt
Peter Eckenberg
Wolfgang Bender
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ECSP034813A publication Critical patent/ECSP034813A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención muestra que los sustituyentes R1, R2, R3, R4 así como A y X tienen los significados dados, así como a procedimientos para su preparación y a su uso como agentes antivirales, especialmente frente a citomegalovirus.The present invention shows that the substituents R1, R2, R3, R4 as well as A and X have the meanings given, as well as procedures for their preparation and their use as antiviral agents, especially against cytomegalovirus.

EC2003004813A 2001-04-19 2003-10-17 ARILSULFONAMIDS AS ANTIVIRAL AGENTS ECSP034813A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10119137 2001-04-19

Publications (1)

Publication Number Publication Date
ECSP034813A true ECSP034813A (en) 2003-12-01

Family

ID=7681939

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2003004813A ECSP034813A (en) 2001-04-19 2003-10-17 ARILSULFONAMIDS AS ANTIVIRAL AGENTS

Country Status (9)

Country Link
KR (1) KR20030088509A (en)
AR (1) AR034309A1 (en)
CO (1) CO5540388A2 (en)
DE (1) DE10148598A1 (en)
EC (1) ECSP034813A (en)
GT (1) GT200200075A (en)
PE (1) PE20021061A1 (en)
SV (1) SV2003000995A (en)
ZA (1) ZA200307892B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7482366B2 (en) * 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
HRP20050168A2 (en) 2002-08-23 2005-10-31 Rigel Pharmaceuticals Pyridyl substituted heterocycles useful for treating or preventing hcv infection
CN100364531C (en) * 2002-12-18 2008-01-30 西托维亚公司 3,5-disubstituted-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof
DE10300109A1 (en) * 2003-01-07 2004-07-15 Bayer Healthcare Ag Method for inhibiting replication of herpes viruses
US7326790B2 (en) 2003-05-02 2008-02-05 Rigel Pharmaceuticals, Inc. Diphenylisoxazole compounds and hydro isomers thereof
US8580842B2 (en) 2003-09-30 2013-11-12 Abbott Gmbh & Co. Kg Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
WO2005049065A2 (en) 2003-11-19 2005-06-02 Rigel Pharmaceuticals, Inc. Synergistic combinations of dihaloacetamide with interferon or ribavirin for treatment hcv infections
US7514434B2 (en) 2004-02-23 2009-04-07 Rigel Pharmaceuticals, Inc. Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof
JP2008540425A (en) 2005-05-02 2008-11-20 ライジェル ファーマシューティカルズ， インコーポレイテッド Heterocyclic antiviral compounds containing metabolizable moieties and uses thereof
US8486979B2 (en) 2006-12-12 2013-07-16 Abbvie Inc. 1,2,4 oxadiazole compounds and methods of use thereof
UY30846A1 (en) 2006-12-30 2008-07-31 Abbott Gmbh & Amp OXINDOL DERIVATIVES REPLACED, MEDICINES THAT UNDERSTAND AND USE THEMSELVES
US20080255203A1 (en) * 2007-04-12 2008-10-16 Abbott Laboratories Heterocyclic compounds and their methods of use
US8703775B2 (en) 2007-12-07 2014-04-22 AbbVie Deutschland GmbH & Co. KG Amidomethyl-substituted oxindole derivatives and the use thereof for the treatment of vasopressin-dependent illnesses
CA2707671C (en) 2007-12-07 2016-02-02 Abbott Gmbh & Co. Kg 5,6-disubstituted oxindole-derivatives and use thereof for treating vasopressine-dependent diseases
US8703774B2 (en) 2007-12-07 2014-04-22 AbbVie Deutschland GmbH & Co. KG Carbamate-substituted oxindole derivatives and use thereof for the treatment of vasopressin-dependent diseases
CA2707669C (en) 2007-12-07 2016-07-05 Wilfried Braje 5-halogen-substituted oxindole derivatives and use thereof for treating vasopressine-dependent diseases
EP2435080A2 (en) 2009-05-29 2012-04-04 Abbott Laboratories Pharmaceutical compositions for the treatment of pain

Also Published As

Publication number Publication date
KR20030088509A (en) 2003-11-19
AR034309A1 (en) 2004-02-18
CO5540388A2 (en) 2005-07-29
PE20021061A1 (en) 2002-12-12
DE10148598A1 (en) 2002-10-24
GT200200075A (en) 2002-12-24
ZA200307892B (en) 2004-10-11
SV2003000995A (en) 2003-03-18

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