ECSP034813A - Arilsulfonamidas como agentes antivirales - Google Patents

Arilsulfonamidas como agentes antivirales

Info

Publication number
ECSP034813A
ECSP034813A EC2003004813A ECSP034813A ECSP034813A EC SP034813 A ECSP034813 A EC SP034813A EC 2003004813 A EC2003004813 A EC 2003004813A EC SP034813 A ECSP034813 A EC SP034813A EC SP034813 A ECSP034813 A EC SP034813A
Authority
EC
Ecuador
Prior art keywords
antiviral agents
arilsulfonamids
well
substituents
procedures
Prior art date
Application number
EC2003004813A
Other languages
English (en)
Inventor
Joerg Keldenich
Tobias Wunberg
Juergen Reefschlaeger
Kerstin Henninger
Siegfried Raddatz
Armin Kern
Gunther Schmidt
Peter Eckenberg
Wolfgang Bender
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ECSP034813A publication Critical patent/ECSP034813A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención muestra que los sustituyentes R1, R2, R3, R4 así como A y X tienen los significados dados, así como a procedimientos para su preparación y a su uso como agentes antivirales, especialmente frente a citomegalovirus.
EC2003004813A 2001-04-19 2003-10-17 Arilsulfonamidas como agentes antivirales ECSP034813A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10119137 2001-04-19

Publications (1)

Publication Number Publication Date
ECSP034813A true ECSP034813A (es) 2003-12-01

Family

ID=7681939

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2003004813A ECSP034813A (es) 2001-04-19 2003-10-17 Arilsulfonamidas como agentes antivirales

Country Status (9)

Country Link
KR (1) KR20030088509A (es)
AR (1) AR034309A1 (es)
CO (1) CO5540388A2 (es)
DE (1) DE10148598A1 (es)
EC (1) ECSP034813A (es)
GT (1) GT200200075A (es)
PE (1) PE20021061A1 (es)
SV (1) SV2003000995A (es)
ZA (1) ZA200307892B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7482366B2 (en) * 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
HRP20050168A2 (en) * 2002-08-23 2005-10-31 Rigel Pharmaceuticals Pyridyl substituted heterocycles useful for treating or preventing hcv infection
JP2006516250A (ja) * 2002-12-18 2006-06-29 サイトビア インコーポレイティッド カスパーゼ活性化剤およびアポトーシス誘導物質としての３，５−二置換−［１，２，４］−オキサジアゾールおよびそれらの誘導体ならびにそれらの使用
DE10300109A1 (de) * 2003-01-07 2004-07-15 Bayer Healthcare Ag Methode zur Inhibition der Replikation von Herpesviren
US7326790B2 (en) 2003-05-02 2008-02-05 Rigel Pharmaceuticals, Inc. Diphenylisoxazole compounds and hydro isomers thereof
US8580842B2 (en) 2003-09-30 2013-11-12 Abbott Gmbh & Co. Kg Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
US7410979B2 (en) 2003-11-19 2008-08-12 Rigel Pharmaceuticals, Inc. Synergistically effective combinations of dihaloacetamide compounds and interferon or ribavirin against HCV infections
US7514434B2 (en) 2004-02-23 2009-04-07 Rigel Pharmaceuticals, Inc. Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof
JP2008540425A (ja) 2005-05-02 2008-11-20 ライジェル ファーマシューティカルズ， インコーポレイテッド 代謝可能部分を含む複素環式抗ウイルス性化合物およびその使用
US8486979B2 (en) 2006-12-12 2013-07-16 Abbvie Inc. 1,2,4 oxadiazole compounds and methods of use thereof
UY30846A1 (es) 2006-12-30 2008-07-31 Abbott Gmbh & Amp Derivados de oxindol sustituidos, medicamentos que los comprenden y uso de los mismos
US20080255203A1 (en) * 2007-04-12 2008-10-16 Abbott Laboratories Heterocyclic compounds and their methods of use
EP2231644B1 (de) 2007-12-07 2014-01-15 AbbVie Deutschland GmbH & Co KG 5,6-Disubstitutierte Oxindol-Derivate und ihre Verwendung zur Herstellung eines Medikaments zur Behandlung von Vasopressin-abhängigen Erkrankungen
US8703774B2 (en) 2007-12-07 2014-04-22 AbbVie Deutschland GmbH & Co. KG Carbamate-substituted oxindole derivatives and use thereof for the treatment of vasopressin-dependent diseases
NZ586651A (en) 2007-12-07 2012-06-29 Abbott Gmbh & Co Kg 5-halogen-substituted oxindole derivatives and use thereof for treating vasopressine-dependent diseases
ES2398676T3 (es) 2007-12-07 2013-03-20 Abbott Gmbh & Co. Kg Derivados de oxindol sustituidos con amidometilo y su uso para la producción de un medicamento para el tratamiento de enfermedades dependientes de la vasopresina
US9040568B2 (en) 2009-05-29 2015-05-26 Abbvie Inc. Pharmaceutical compositions for the treatment of pain

Also Published As

Publication number Publication date
ZA200307892B (en) 2004-10-11
CO5540388A2 (es) 2005-07-29
DE10148598A1 (de) 2002-10-24
PE20021061A1 (es) 2002-12-12
GT200200075A (es) 2002-12-24
AR034309A1 (es) 2004-02-18
SV2003000995A (es) 2003-03-18
KR20030088509A (ko) 2003-11-19

Similar Documents

Publication Publication Date Title
UY27226A1 (es) Pirazolopirimidinas como agentes terapéuticos
ECSP045245A (es) N-aril-2-oxazolidinona-5-carboxamidas y sus derivados
ECSP034773A (es) Pirazolopirimmidinas como agentes terapeuticos
SV2004001432A (es) 2-tio-3,5-diciano-4-4fenil-6-aminopiridinas substituidas y su uso ref. lea 35 640-sv
UY28342A1 (es) Nuevos compuestos
AR030185A1 (es) Glutarimidas sustituidas, su preparacion, medicamentos que las contienen, y uso de las mismas para la fabricacion de medicamentos, especialmente inmunomoduladores, como asi tambien inhibidores de angiopatias y/o enfermedades hematologicas/oncologicas
HN2002000300A (es) Nuevos derivados de piperazina
PA8570901A1 (es) Derivados de acil-4-carboxifenilurea, procedimientos para su preparacion y su uso
UY28348A1 (es) Compuestos novedosos
CY1105386T1 (el) Βενζοϋλοσουλφοναμιδια και σουλφονυλβενζαμιδινες για χρηση σαν παραγοντες κατα του ογκου
AR035284A1 (es) Formulaciones en combinacion de derivados de propanol-amina sustituidos con arilo, junto con otras sustancias activas y su utilizacion
PA8575601A1 (es) Procedimiento para su preparacion, medicamentos que comprenden estos compuestos y su uso
UY27263A1 (es) Nuevas arilsulfonamidas como agentes antivirales
ECSP044999A (es) Agentes antidiabeticos
SV2003000995A (es) Nuevas arilsulfonamidas como agentes antivirales ref. lea35214-sv
UY28694A1 (es) Nuevos compuestos
GT199900010A (es) Nuevas sulfonamidas naftil- y anilido-substituidas.
ECSP066481A (es) Formulaciones que contienen cobre
AR030537A1 (es) Acidos quinolincarboxilicos y naftiridincarboxilico antibacterianos
AR020563A1 (es) Compuestos (poli)tia-alquinoicos y sus derivados, composiciones que los incluyen y su utilizacion
AR027575A1 (es) Benzoilciclohexenonas substituidas
PA8557201A1 (es) Compuestos basicos lineales que tienen actividad antagonista de nk-2 y su formulaciones
CU23309B7 (es) Compuestos anã logos de astrobilurinas y su uso como acaricida e insecticida
SV2004001441A (es) Compuestos de isocromano ref. x-14205
BR0110490A (pt) Agentes de tingimento contendo derivados de n-heteroarilmetil-m-fenilenodiamina para fibras de queratina bem como novos derivados de n-heteroarilmetil-m-fenilenodiamina