ECSP034852A - Moduladores de receptores ampa alostéricos naftotiazina-positivos (paarm) - Google Patents
Moduladores de receptores ampa alostéricos naftotiazina-positivos (paarm)Info
- Publication number
- ECSP034852A ECSP034852A EC2003004852A ECSP034852A ECSP034852A EC SP034852 A ECSP034852 A EC SP034852A EC 2003004852 A EC2003004852 A EC 2003004852A EC SP034852 A ECSP034852 A EC SP034852A EC SP034852 A ECSP034852 A EC SP034852A
- Authority
- EC
- Ecuador
- Prior art keywords
- ampa
- paarm
- naftotiazine
- alosteric
- receptors modulators
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/02—1,2-Thiazines; Hydrogenated 1,2-thiazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Abstract
La presente invención se refiere a nuevos moduladores de receptores AMPA alotéricos positivos de la fórmula general (I), donde R1, R2, R3, R4 y R5 pueden tener los significados dados en las especificaciones y reivindicaciones, procesos para la preparación de éstos y el uso de los mismos como composiciones farmacéuticas
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10123952A DE10123952A1 (de) | 2001-05-17 | 2001-05-17 | Neue positive allosterische AMPA-Rezeptor Modulatoren (PAARM), Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP034852A true ECSP034852A (es) | 2003-12-24 |
Family
ID=7685080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2003004852A ECSP034852A (es) | 2001-05-17 | 2003-11-17 | Moduladores de receptores ampa alostéricos naftotiazina-positivos (paarm) |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP1404340A1 (es) |
| JP (1) | JP2004529980A (es) |
| KR (1) | KR20040007572A (es) |
| CN (1) | CN1533278A (es) |
| AR (1) | AR036332A1 (es) |
| BG (1) | BG108324A (es) |
| BR (1) | BR0209796A (es) |
| CA (1) | CA2449189A1 (es) |
| CO (1) | CO5550460A2 (es) |
| CZ (1) | CZ20033112A3 (es) |
| DE (1) | DE10123952A1 (es) |
| EA (1) | EA006608B1 (es) |
| EC (1) | ECSP034852A (es) |
| EE (1) | EE200300566A (es) |
| HR (1) | HRP20030933A2 (es) |
| HU (1) | HUP0401273A3 (es) |
| IL (1) | IL158642A0 (es) |
| MX (1) | MXPA03010373A (es) |
| NO (1) | NO20035088D0 (es) |
| NZ (1) | NZ530154A (es) |
| PL (1) | PL364053A1 (es) |
| SK (1) | SK14222003A3 (es) |
| UY (1) | UY27290A1 (es) |
| WO (1) | WO2002100411A1 (es) |
| YU (1) | YU90403A (es) |
| ZA (1) | ZA200308466B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010501597A (ja) * | 2006-08-31 | 2010-01-21 | ザ ガバナーズ オブ ザ ユニバーシティー オブ アルバータ | 正のアロステリックａｍｐａ受容体モジュレーターを用いて呼吸抑制を阻害する方法 |
| CN111518058B (zh) * | 2020-05-29 | 2021-03-09 | 四川大学华西医院 | 一种噁噻嗪类化合物及其用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4345297A (en) * | 1996-09-17 | 1998-04-14 | Regents Of The University Of California, The | Benzothiadiazide derivatives and their use as allosteric up-modulators of the ampa receptor |
| US6346526B1 (en) * | 1998-06-25 | 2002-02-12 | Merck & Co., Inc. | Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment |
| DE10004572A1 (de) * | 2000-02-02 | 2001-08-09 | Boehringer Ingelheim Pharma | Neue positive allosterische AMPA-Rezeptor Modulatoren (PAARM), Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
-
2001
- 2001-05-17 DE DE10123952A patent/DE10123952A1/de not_active Withdrawn
-
2002
- 2002-05-15 EA EA200301167A patent/EA006608B1/ru not_active IP Right Cessation
- 2002-05-15 MX MXPA03010373A patent/MXPA03010373A/es unknown
- 2002-05-15 YU YU90403A patent/YU90403A/sh unknown
- 2002-05-15 UY UY27290A patent/UY27290A1/es not_active Application Discontinuation
- 2002-05-15 EP EP02750931A patent/EP1404340A1/en not_active Withdrawn
- 2002-05-15 CZ CZ20033112A patent/CZ20033112A3/cs unknown
- 2002-05-15 SK SK1422-2003A patent/SK14222003A3/sk unknown
- 2002-05-15 CN CNA028100832A patent/CN1533278A/zh active Pending
- 2002-05-15 NZ NZ530154A patent/NZ530154A/en unknown
- 2002-05-15 WO PCT/EP2002/005338 patent/WO2002100411A1/en not_active Ceased
- 2002-05-15 CA CA002449189A patent/CA2449189A1/en not_active Abandoned
- 2002-05-15 JP JP2003503232A patent/JP2004529980A/ja not_active Abandoned
- 2002-05-15 IL IL15864202A patent/IL158642A0/xx unknown
- 2002-05-15 HR HR20030933A patent/HRP20030933A2/xx not_active Application Discontinuation
- 2002-05-15 EE EEP200300566A patent/EE200300566A/xx unknown
- 2002-05-15 PL PL02364053A patent/PL364053A1/xx not_active Application Discontinuation
- 2002-05-15 HU HU0401273A patent/HUP0401273A3/hu unknown
- 2002-05-15 BR BR0209796-6A patent/BR0209796A/pt not_active IP Right Cessation
- 2002-05-15 KR KR10-2003-7014965A patent/KR20040007572A/ko not_active Withdrawn
- 2002-05-17 AR ARP020101827A patent/AR036332A1/es unknown
-
2003
- 2003-10-30 ZA ZA200308466A patent/ZA200308466B/en unknown
- 2003-11-07 BG BG108324A patent/BG108324A/bg unknown
- 2003-11-14 NO NO20035088A patent/NO20035088D0/no not_active Application Discontinuation
- 2003-11-17 EC EC2003004852A patent/ECSP034852A/es unknown
- 2003-12-01 CO CO03105591A patent/CO5550460A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR0209796A (pt) | 2004-06-01 |
| ZA200308466B (en) | 2004-05-24 |
| MXPA03010373A (es) | 2004-03-16 |
| CA2449189A1 (en) | 2002-12-19 |
| KR20040007572A (ko) | 2004-01-24 |
| CO5550460A2 (es) | 2005-08-31 |
| YU90403A (sh) | 2006-05-25 |
| IL158642A0 (en) | 2004-05-12 |
| CN1533278A (zh) | 2004-09-29 |
| HUP0401273A2 (hu) | 2004-10-28 |
| PL364053A1 (en) | 2004-12-13 |
| CZ20033112A3 (en) | 2004-03-17 |
| UY27290A1 (es) | 2002-12-31 |
| NO20035088L (no) | 2003-11-14 |
| JP2004529980A (ja) | 2004-09-30 |
| NO20035088D0 (no) | 2003-11-14 |
| SK14222003A3 (sk) | 2004-05-04 |
| BG108324A (bg) | 2004-12-30 |
| HUP0401273A3 (en) | 2006-11-28 |
| AR036332A1 (es) | 2004-09-01 |
| DE10123952A1 (de) | 2002-11-21 |
| HRP20030933A2 (en) | 2004-04-30 |
| EA006608B1 (ru) | 2006-02-24 |
| WO2002100411A1 (en) | 2002-12-19 |
| EE200300566A (et) | 2004-02-16 |
| NZ530154A (en) | 2005-09-30 |
| EP1404340A1 (en) | 2004-04-07 |
| EA200301167A1 (ru) | 2004-06-24 |
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