ECSP045123A - Composición para catéteres y sus usos - Google Patents

Composición para catéteres y sus usos

Info

Publication number
ECSP045123A
ECSP045123A EC2004005123A ECSP045123A ECSP045123A EC SP045123 A ECSP045123 A EC SP045123A EC 2004005123 A EC2004005123 A EC 2004005123A EC SP045123 A ECSP045123 A EC SP045123A EC SP045123 A ECSP045123 A EC SP045123A
Authority
EC
Ecuador
Prior art keywords
composition
amount
catheters
efficacy
fibrin
Prior art date
Application number
EC2004005123A
Other languages
English (en)
Inventor
Charles P Sembra
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of ECSP045123A publication Critical patent/ECSP045123A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Una composición útil para retirar coágulos de sangre relacionados con la fibrina de un catéter, composición que contiene agua, una cantidad con eficacia fibrinolítica de un activador del plasminógeno, y una cantidad de alcohol orgánico bacteriostático con eficacia preservativa. La composición no incluye un agente quelante.
EC2004005123A 2001-11-26 2004-05-26 Composición para catéteres y sus usos ECSP045123A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33336901P 2001-11-26 2001-11-26

Publications (1)

Publication Number Publication Date
ECSP045123A true ECSP045123A (es) 2004-07-23

Family

ID=23302492

Family Applications (2)

Application Number Title Priority Date Filing Date
EC2004005123A ECSP045123A (es) 2001-11-26 2004-05-26 Composición para catéteres y sus usos
EC2004005123F ECSDI045123S (es) 2001-11-26 2004-05-26

Family Applications After (1)

Application Number Title Priority Date Filing Date
EC2004005123F ECSDI045123S (es) 2001-11-26 2004-05-26

Country Status (28)

Country Link
US (3) US20030206906A1 (es)
EP (1) EP1455858A4 (es)
JP (1) JP4458240B2 (es)
KR (2) KR20100102745A (es)
CN (1) CN100478027C (es)
AR (1) AR037437A1 (es)
AU (2) AU2002365408B2 (es)
BR (1) BR0215098A (es)
CA (1) CA2467645C (es)
CO (1) CO5580795A2 (es)
EA (1) EA007594B1 (es)
EC (2) ECSP045123A (es)
HR (1) HRP20040502A2 (es)
HU (1) HUP0600436A3 (es)
IL (2) IL162083A0 (es)
IS (1) IS7275A (es)
ME (1) ME00015B (es)
MX (1) MXPA04004948A (es)
MY (1) MY140404A (es)
NO (1) NO331700B1 (es)
NZ (1) NZ533029A (es)
PL (1) PL371760A1 (es)
RS (1) RS46204A (es)
TW (1) TWI262794B (es)
UA (1) UA81235C2 (es)
UY (1) UY27550A1 (es)
WO (1) WO2003045466A2 (es)
ZA (1) ZA200404024B (es)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ533029A (en) 2001-11-26 2006-05-26 Genentech Inc Composition useful for removal of fibrin-bound blood clot from a catheter comprises water, a plasminogen activator and an alcohol
US7128923B2 (en) * 2003-03-31 2006-10-31 Procyte Corporation Preserved and stable compositions containing peptide copper complexes and method related thereto
ES2453496T3 (es) * 2006-08-28 2014-04-08 Omnio Healer Ab Diana farmacológica novedosa de prevención y tratamiento de enfermedad periodontal, mejora de la cicatrización de heridas periodontales y promoción de la salud oral
US8318661B2 (en) 2006-08-28 2012-11-27 Omnio Healer Ab Candidates against infection
CA2668347C (en) 2006-11-07 2017-06-20 Genentech, Inc. Tissue plasminogen activator variant uses
RU2323001C1 (ru) * 2007-05-30 2008-04-27 Общество с ограниченной ответственностью "Научно-производственное предприятие "Техноген" Фармацевтическая композиция, обладающая фибринолитическим действием
WO2008150375A1 (en) 2007-06-01 2008-12-11 Arrow International, Inc. Combined fibrinolytic and antimicrobial catheter and uses thereof
CN103181893A (zh) * 2007-09-07 2013-07-03 联合治疗公司 针对革兰氏阴性细菌具有选择性杀菌活性的缓冲液及其使用方法
US9333280B2 (en) 2009-02-25 2016-05-10 Teleflex Medical Incorporated Stabilized enzyme compositions
US8545459B2 (en) * 2009-02-25 2013-10-01 Teleflex Medical Incorporated Stabilized enzyme compositions
WO2011019710A2 (en) * 2009-08-10 2011-02-17 Proviflo, Llc Catheter lock solutions utilizing tocopheraol and mid-chain fatty acids
CN103083726A (zh) * 2013-03-04 2013-05-08 昆明市第一人民医院 一种肝脏组织脱细胞液
WO2016201269A2 (en) 2015-06-11 2016-12-15 Proviflo, Llc Graft-port hemodialysis systems, devices and methods

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US5000185A (en) 1986-02-28 1991-03-19 Cardiovascular Imaging Systems, Inc. Method for intravascular two-dimensional ultrasonography and recanalization
US5019096A (en) * 1988-02-11 1991-05-28 Trustees Of Columbia University In The City Of New York Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same
US5270198A (en) 1988-05-20 1993-12-14 Genentech, Inc. DNA molecules encoding variants of tissue plasminogen activators, vectors, and host cells
GB8820945D0 (en) * 1988-09-07 1988-10-05 Smith & Nephew Medical articles
FR2661790B1 (fr) * 1990-05-03 1995-08-25 France Etat Dispositif d'amplification tres large bande continu-hyperfrequences, notamment realisable en circuit integre.
WO1991017724A1 (en) 1990-05-17 1991-11-28 Harbor Medical Devices, Inc. Medical device polymer
US5399158A (en) 1990-05-31 1995-03-21 The United States Of America As Represented By The Secretary Of The Army Method of lysing thrombi
US5363754A (en) * 1991-09-03 1994-11-15 Grainco Queensland Co-Operative Association Limited Apparatus for preparing animal feedstuff from cotton seed
JPH05291891A (ja) * 1992-02-14 1993-11-05 Ricoh Co Ltd 一次乱数パルス列発生回路装置
ATE155816T1 (de) * 1992-06-03 1997-08-15 Genentech Inc Varianten des gewebeplasminogenaktivators mit verbesserter therapeutischer wirkung
US5688516A (en) * 1992-11-12 1997-11-18 Board Of Regents, The University Of Texas System Non-glycopeptide antimicrobial agents in combination with an anticoagulant, an antithrombotic or a chelating agent, and their uses in, for example, the preparation of medical devices
US5362754A (en) 1992-11-12 1994-11-08 Univ. Of Tx Md Anderson Cancer Center M-EDTA pharmaceutical preparations and uses thereof
DK0730590T3 (da) 1993-11-24 2001-03-19 Du Pont Pharm Co Isoxazolin og isozazol fibrinogenreceptorantagonister
US5849736A (en) 1993-11-24 1998-12-15 The Dupont Merck Pharmaceutical Company Isoxazoline and isoxazole fibrinogen receptor antagonists
US5885967A (en) * 1994-03-04 1999-03-23 Eli Lilly And Company Antithrombotic agents
US5509896A (en) 1994-09-09 1996-04-23 Coraje, Inc. Enhancement of thrombolysis with external ultrasound
AU716005B2 (en) * 1995-06-07 2000-02-17 Cook Medical Technologies Llc Implantable medical device
US5772640A (en) * 1996-01-05 1998-06-30 The Trustees Of Columbia University Of The City Of New York Triclosan-containing medical devices
US5932299A (en) * 1996-04-23 1999-08-03 Katoot; Mohammad W. Method for modifying the surface of an object
US5840733A (en) * 1996-07-01 1998-11-24 Redcell, Canada, Inc. Methods and compositions for producing novel conjugates of thrombin inhibitors and endogenous carriers resulting in anti-thrombins with extended lifetimes
US5837688A (en) * 1996-11-27 1998-11-17 Gelfand; Mathew I. Use of thrombolytic reagents for prevention of vascular disease
GB9626795D0 (en) * 1996-12-23 1997-02-12 Geistlich Soehne Ag Combating infection in delivery systems
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US5981826A (en) * 1997-05-05 1999-11-09 Georgia Tech Research Corporation Poly(vinyl alcohol) cryogel
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US6206914B1 (en) * 1998-04-30 2001-03-27 Medtronic, Inc. Implantable system with drug-eluting cells for on-demand local drug delivery
US6166007A (en) * 1998-07-02 2000-12-26 Sodemann; Klaus Antimicrobial locks comprising taurinamide derivatives and carboxylic acids and/or salts thereof
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CN1346292A (zh) 1999-03-11 2002-04-24 杜邦药品公司 凝血因子Xa抑制剂与阿司匹林、组织纤溶酶原激活物(TPA)、GPⅡb/Ⅲa拮抗剂、低分子量肝素或肝素联合用于治疗血栓形成
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US6592564B2 (en) * 1999-07-23 2003-07-15 Vasca, Inc. Methods and kits for locking and disinfecting implanted catheters
US6350251B1 (en) 2000-01-18 2002-02-26 Biolink Corporation Biocidal locks
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US6772640B1 (en) * 2000-10-10 2004-08-10 Mks Instruments, Inc. Multi-temperature heater for use with pressure transducers
US20050215978A1 (en) 2001-05-25 2005-09-29 Ash Stephen R Method of enhancing catheter patency using a citrate salt catheter lock solution
NZ533029A (en) 2001-11-26 2006-05-26 Genentech Inc Composition useful for removal of fibrin-bound blood clot from a catheter comprises water, a plasminogen activator and an alcohol
US20070014779A1 (en) 2002-11-14 2007-01-18 Genentech, Inc. Plasminogen activator variant formulations
ATE354380T1 (de) 2003-02-03 2007-03-15 Polaschegg Hans-Dietrich Dr Te Zusammensetzung zur prävention von infektionen durch subkutane prothesen
US7696182B2 (en) 2004-11-02 2010-04-13 Nd Partners, Llc Antimicrobial locking solutions comprising taurinamide derivatives and biologically acceptable salts and acids, with the addition of small concentrations of heparin
US7749529B2 (en) 2005-02-08 2010-07-06 Ash Access Technology, Inc. Catheter lock solution comprising citrate and a paraben
CA2668347C (en) 2006-11-07 2017-06-20 Genentech, Inc. Tissue plasminogen activator variant uses

Also Published As

Publication number Publication date
TWI262794B (en) 2006-10-01
TW200303743A (en) 2003-09-16
EA200400712A1 (ru) 2005-06-30
CN1617738A (zh) 2005-05-18
EA007594B1 (ru) 2006-12-29
AU2002365408B2 (en) 2008-04-24
ECSDI045123S (es) 2004-07-23
JP4458240B2 (ja) 2010-04-28
WO2003045466A2 (en) 2003-06-05
ZA200404024B (en) 2005-07-27
CA2467645C (en) 2017-01-17
KR20100102745A (ko) 2010-09-24
RS46204A (sr) 2006-10-27
NZ533029A (en) 2006-05-26
EP1455858A2 (en) 2004-09-15
AU2002365408A1 (en) 2003-06-10
MXPA04004948A (es) 2004-08-11
EP1455858A4 (en) 2006-02-15
US20060257390A1 (en) 2006-11-16
CO5580795A2 (es) 2005-11-30
NO331700B1 (no) 2012-02-27
UY27550A1 (es) 2003-06-30
NO20042693L (no) 2004-08-25
HUP0600436A2 (en) 2006-09-28
HRP20040502A2 (en) 2004-12-31
JP2005510302A (ja) 2005-04-21
HUP0600436A3 (en) 2010-12-28
WO2003045466A3 (en) 2003-10-09
IS7275A (is) 2004-05-21
US20030206906A1 (en) 2003-11-06
BR0215098A (pt) 2004-12-14
US20060246050A1 (en) 2006-11-02
UA81235C2 (en) 2007-12-25
IL162083A0 (en) 2005-11-20
IL162083A (en) 2012-12-31
MY140404A (en) 2009-12-31
US7829082B2 (en) 2010-11-09
CN100478027C (zh) 2009-04-15
MEP8008A (xx) 2010-02-10
ME00015B (me) 2010-06-10
PL371760A1 (en) 2005-06-27
AR037437A1 (es) 2004-11-10
KR20040054803A (ko) 2004-06-25
AU2008203131A1 (en) 2008-08-07
CA2467645A1 (en) 2003-06-05

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