ECSP045140A - Formulaciones farmacéuticas derivadas del platino - Google Patents
Formulaciones farmacéuticas derivadas del platinoInfo
- Publication number
- ECSP045140A ECSP045140A EC2004005140A ECSP045140A ECSP045140A EC SP045140 A ECSP045140 A EC SP045140A EC 2004005140 A EC2004005140 A EC 2004005140A EC SP045140 A ECSP045140 A EC SP045140A EC SP045140 A ECSP045140 A EC SP045140A
- Authority
- EC
- Ecuador
- Prior art keywords
- platinum
- pharmaceutical formulations
- formulations derived
- derived
- formulas
- Prior art date
Links
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 title 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229910052697 platinum Inorganic materials 0.000 title 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 235000014655 lactic acid Nutrition 0.000 abstract 1
- 239000004310 lactic acid Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- DWAFYCQODLXJNR-BNTLRKBRSA-L oxaliplatin Chemical compound O1C(=O)C(=O)O[Pt]11N[C@@H]2CCCC[C@H]2N1 DWAFYCQODLXJNR-BNTLRKBRSA-L 0.000 abstract 1
- 229960001756 oxaliplatin Drugs 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención está dirigida a nuevas fórmulas estables de oxaliplatino, en las cuales el ácido láctico y/o una sal farmacéuticamente aceptable funciona como un medio novedoso para preparar una unidad de dosis con una estabilidad mejorada. También está dentro del alcance de esta invención un método para elaborar tales formulaciones listas para ser administradas y su uso en una terapia contra tumores.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/010,122 US6476068B1 (en) | 2001-12-06 | 2001-12-06 | Platinum derivative pharmaceutical formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP045140A true ECSP045140A (es) | 2004-08-27 |
Family
ID=21744006
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2004005140A ECSP045140A (es) | 2001-12-06 | 2004-06-04 | Formulaciones farmacéuticas derivadas del platino |
Country Status (41)
| Country | Link |
|---|---|
| US (3) | US6476068B1 (es) |
| EP (1) | EP1453517B1 (es) |
| JP (1) | JP2005515202A (es) |
| KR (1) | KR100941210B1 (es) |
| CN (1) | CN100540006C (es) |
| AP (1) | AP1760A (es) |
| AR (1) | AR037629A1 (es) |
| AT (1) | ATE317260T1 (es) |
| AU (1) | AU2002352105B2 (es) |
| BR (1) | BR0214757A (es) |
| CA (1) | CA2468916C (es) |
| CO (1) | CO5580776A2 (es) |
| CR (1) | CR7362A (es) |
| CY (1) | CY1105608T1 (es) |
| DE (1) | DE60209145T2 (es) |
| DK (1) | DK1453517T3 (es) |
| EA (1) | EA008090B1 (es) |
| EC (1) | ECSP045140A (es) |
| ES (1) | ES2258661T3 (es) |
| GE (1) | GEP20063895B (es) |
| HR (1) | HRP20040514A2 (es) |
| HU (1) | HUP0402217A3 (es) |
| IL (2) | IL162348A0 (es) |
| IS (1) | IS2580B (es) |
| MA (1) | MA27153A1 (es) |
| ME (1) | MEP10408A (es) |
| MX (1) | MXPA04005423A (es) |
| MY (1) | MY134422A (es) |
| NO (1) | NO330159B1 (es) |
| NZ (1) | NZ533383A (es) |
| OA (1) | OA12739A (es) |
| PL (1) | PL206755B1 (es) |
| PT (1) | PT1453517E (es) |
| RO (1) | RO121509B1 (es) |
| RS (1) | RS50360B (es) |
| SI (1) | SI21493A (es) |
| TN (1) | TNSN04104A1 (es) |
| TW (1) | TW200409640A (es) |
| UA (1) | UA77728C2 (es) |
| WO (1) | WO2003047587A1 (es) |
| ZA (1) | ZA200404525B (es) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1404689A1 (en) * | 2001-07-02 | 2004-04-07 | Debiopharm S.A. | Oxaliplatin active substance with a very low content of oxalic acid |
| CA2388352A1 (en) * | 2002-05-31 | 2003-11-30 | Voiceage Corporation | A method and device for frequency-selective pitch enhancement of synthesized speed |
| US20040022842A1 (en) * | 2002-06-03 | 2004-02-05 | Mebiopharm Co., Ltd. | Liposome preparations containing oxaliplatin |
| DE10314377A1 (de) * | 2003-03-28 | 2004-10-07 | Stada Arzneimittel Ag | Gebrauchsfertige Oxaliplatin-Lösungen |
| CN102048723A (zh) * | 2003-08-28 | 2011-05-11 | 梅恩医药有限公司 | 含有酸的奥沙利铂制剂 |
| GB2441445B (en) * | 2003-08-28 | 2008-04-23 | Mayne Pharma Ltd | Acid containing oxaliplatin formulation |
| TWI347940B (en) * | 2003-11-07 | 2011-09-01 | Novartis Ag | Methods for synthesizing quinolinone compounds |
| RU2273475C2 (ru) * | 2004-04-06 | 2006-04-10 | Государственное учреждение системы высшего и послевузовского профессионального образования "Сибирский государственный медицинский университет" (ГУ СВ ПО СибГМУ) | Способ лечения диссеминированного колоректального рака |
| US7795205B2 (en) * | 2004-04-12 | 2010-09-14 | Canyon Pharmaceuticals, Inc. | Methods for effecting regression of tumor mass and size in a metastasized pancreatic tumor |
| WO2005120480A1 (ja) * | 2004-06-09 | 2005-12-22 | Taiho Pharmaceutical Co., Ltd. | 抗腫瘍効果増強剤、抗腫瘍剤及び癌治療方法 |
| EP1658300A1 (en) * | 2004-07-12 | 2006-05-24 | Sicor Inc. | Cis-diiodo- (trans-l-1,2-cyclohexanediamine) platinum (ii) complex and processes for preparing high purity oxaliplatin |
| US20060063833A1 (en) * | 2004-09-22 | 2006-03-23 | Edgar Schridde | Ready-to-use oxaliplatin solutions |
| US20060063720A1 (en) * | 2004-09-22 | 2006-03-23 | Edgar Schridde | Oxaliplatin solution concentrate |
| DE102004052877B4 (de) * | 2004-11-02 | 2008-06-19 | Ebewe Pharma Ges.M.B.H. Nfg.Kg | Stabile wässrige Formulierungen eines Platin-Derivats |
| CN1311818C (zh) * | 2004-11-22 | 2007-04-25 | 山东蓝金生物工程有限公司 | 一种抗实体肿瘤的药物组合物 |
| DE102004063764A1 (de) * | 2004-12-29 | 2006-07-13 | Hexal Ag | Kunststoff-Flasche für Oxaliplatin |
| JP2006248978A (ja) | 2005-03-10 | 2006-09-21 | Mebiopharm Co Ltd | 新規なリポソーム製剤 |
| AU2005329764B2 (en) * | 2005-03-28 | 2010-08-12 | Dabur Pharma Ltd. | Stable pharmaceutical compositions of platinum (II) antitumour agents |
| WO2006124413A2 (en) * | 2005-05-13 | 2006-11-23 | Novartis Ag | Methods for treating drug resistant cancer |
| DE102005038347A1 (de) * | 2005-08-11 | 2007-02-15 | Hexal Ag | Herstellung einer Oxaliplatin-Lösung und Behälter sowie Behälter-Set mit der Lösung |
| WO2007029268A2 (en) * | 2005-09-05 | 2007-03-15 | Dabur Pharma Limited | Stable oxaliplatin formulation |
| BRPI0619370A2 (pt) * | 2005-11-29 | 2011-09-27 | Novartis Ag | formulações de quinolinonas |
| US20090076139A1 (en) * | 2007-09-19 | 2009-03-19 | Protia, Llc | Deuterium-enriched oxalplatin |
| EP2152239A1 (en) | 2007-11-12 | 2010-02-17 | Intas Pharmaceuticals Limited | Stable oxaliplatin composition for parenteral administration |
| EP2259776A4 (en) * | 2008-02-29 | 2011-03-16 | Eagle Pharmaceuticals Inc | USEFUL TOPOTECAN SOLUTIONS |
| TW201021855A (en) * | 2008-11-13 | 2010-06-16 | Taigen Biotechnology Co Ltd | Lyophilization formulation |
| EP2481396A4 (en) | 2009-09-21 | 2014-03-05 | Jw Pharmaceutical Corp | OXALIPLATIN NANOPARTICLES AND MANUFACTURING METHOD THEREFOR |
| WO2012006101A2 (en) | 2010-06-28 | 2012-01-12 | The General Hospital Corporation | Blood substitutes and uses thereof |
| CN102274171A (zh) * | 2011-08-04 | 2011-12-14 | 上海希迪制药有限公司 | 一种奥沙利铂注射剂 |
| JP2015524411A (ja) | 2012-07-18 | 2015-08-24 | オニキス セラピューティクス, インク.Onyx Therapeutics, Inc. | エポキシケトン系プロテアソーム阻害剤のリポソーム組成物 |
| JP5929607B2 (ja) * | 2012-08-06 | 2016-06-08 | ニプロ株式会社 | オキサリプラチン製剤 |
| CN102885765B (zh) * | 2012-10-25 | 2013-11-06 | 哈药集团生物工程有限公司 | 一种盐酸伊立替康注射液及其制备方法 |
| US10098813B2 (en) * | 2014-09-03 | 2018-10-16 | Sun Pharmaceutical Industries Limited | Perfusion dosage form |
| KR101683635B1 (ko) | 2014-12-29 | 2016-12-09 | 가천대학교 산학협력단 | 락테이트 금속염을 포함하는 암 치료용 약학 조성물 |
| DK3256133T3 (da) * | 2015-02-13 | 2022-10-24 | Sun Pharmaceutical Ind Ltd | Intravenøs infusionsdoseringsform |
| KR102293907B1 (ko) | 2015-06-30 | 2021-08-26 | 한미약품 주식회사 | 이리노테칸 함유 경구용 고형제제 및 그 제조방법 |
| ES2968415T3 (es) | 2016-02-09 | 2024-05-09 | Sun Pharmaceutical Ind Ltd | Sistema de perfusión |
| EP3538546B1 (en) | 2016-11-14 | 2025-01-08 | Novartis AG | Compositions, methods, and therapeutic uses related to fusogenic protein minion |
| CN111587110A (zh) | 2018-01-12 | 2020-08-25 | 麦提麦迪制药有限公司 | 治疗慢性炎症性疾病的方法 |
| KR101998246B1 (ko) | 2018-08-22 | 2019-07-10 | 주식회사 메타파인즈 | 금속이온에 결합된 이온화합물을 포함하는 암 치료용 약학 조성물 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6041077B2 (ja) | 1976-09-06 | 1985-09-13 | 喜徳 喜谷 | 1,2‐ジアミノシクロヘキサン異性体のシス白金(2)錯体 |
| US5041578A (en) * | 1988-11-22 | 1991-08-20 | Board Of Regents, The University Of Texas System | Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as antitumor agents |
| WO1993009782A1 (en) | 1991-11-15 | 1993-05-27 | Smithkline Beecham Corporation | Combination chemotherapy |
| JPH0776230B2 (ja) | 1992-01-13 | 1995-08-16 | 田中貴金属工業株式会社 | 白金化合物の製造方法 |
| JP2673331B2 (ja) | 1993-01-12 | 1997-11-05 | 田中貴金属工業 株式会社 | 光学的に高純度なシス―オキザラート(トランス―1―1,2―シクロヘキサンジアミン)白金(▲ii▼) |
| JPH06287021A (ja) | 1992-04-22 | 1994-10-11 | Tanaka Kikinzoku Kogyo Kk | 光学活性な白金錯化合物の光学的分割方法 |
| WO1994012193A1 (fr) | 1992-11-24 | 1994-06-09 | Debiopharm S.A. | Combinaison de cisplatine avec l'oxaliplatine |
| ES2224200T3 (es) * | 1992-11-27 | 2005-03-01 | Mayne Pharma (Usa) Inc. | Composicion inyectable estable de paclitaxel. |
| JP3025602B2 (ja) | 1993-05-21 | 2000-03-27 | デビオファーム エス.アー. | 光学的に高純度なシス−オキザラート(トランス−l−1,2−シクロヘキサンジアミン)白金(II)錯体の製造方法 |
| US5455270A (en) * | 1993-08-11 | 1995-10-03 | Bristol-Myers Squibb Co. | Stabilized solutions of platinum(II) antitumor agents |
| JP3547755B2 (ja) | 1994-08-08 | 2004-07-28 | デビオファーム・エス・アー | オキサリプラティヌムの医薬的に安定な製剤 |
| EP0715854B1 (en) | 1994-11-11 | 2003-09-10 | Debiopharm S.A. | Carcinostatic compositions containing cis-oxaliplatinum and one or more other compatible carcinostatic substances |
| US5919816A (en) | 1994-11-14 | 1999-07-06 | Bionumerik Pharmaceuticals, Inc. | Formulations and methods of reducing toxicity of antineoplastic agents |
| WO1996026949A1 (en) * | 1995-02-28 | 1996-09-06 | Debiopharm Sa | Novel platinum (iv) complexes, process for producing the same, and carcinostatic agents containing the same |
| US5776959A (en) | 1995-06-05 | 1998-07-07 | Washington University | Anticonvulsant and anxiolytic lactam and thiolactam derivatives |
| JP3154399B2 (ja) | 1996-07-04 | 2001-04-09 | デビオファーム エス.アー. | 白金化合物の製造方法 |
| WO1997033894A1 (fr) * | 1996-03-11 | 1997-09-18 | Debiopharm Sa | Complexes de platine dinucleaires, procede pour leur preparation et compositions pharmaceutiques en contenant |
| DE69725747T2 (de) | 1996-08-23 | 2004-07-29 | Sequus Pharmaceuticals, Inc., Menlo Park | Liposome enthaltend cisplatin |
| US6056973A (en) | 1996-10-11 | 2000-05-02 | Sequus Pharmaceuticals, Inc. | Therapeutic liposome composition and method of preparation |
| IL131008A (en) | 1997-02-05 | 2003-06-24 | Upjohn Co | Lipid complexes and liposomes of highly insoluble platinum complex dicarboxylate |
| AU6178198A (en) | 1997-03-07 | 1998-09-22 | Sanofi Pharmaceuticals, Inc. | Method of treating a tumor |
| GB9727523D0 (en) | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
| GB9804013D0 (en) * | 1998-02-25 | 1998-04-22 | Sanofi Sa | Formulations |
| US6866857B1 (en) | 1998-10-14 | 2005-03-15 | Debiopharm S.A. | Oxalipatinum preparation packaging |
| CA2382389C (fr) | 1999-08-30 | 2010-06-29 | Debiopharm S.A. | Preparation pharmaceutique stable d'oxaliplatine pour administration par voie parenterale |
| AU2001240001A1 (en) | 2000-03-08 | 2001-09-17 | Bristol-Myers Squibb Company | Oral dosage form for administration of the combination of tegafur, uracil, folinic acid, and oxaliplatin and method of using the same |
| SE0003026D0 (sv) * | 2000-08-25 | 2000-08-25 | Kerstin Sunnerheim | Use for conifer sapling protection |
-
2001
- 2001-12-06 US US10/010,122 patent/US6476068B1/en not_active Expired - Fee Related
-
2002
- 2002-08-22 US US10/225,607 patent/US6673805B2/en not_active Expired - Fee Related
- 2002-11-15 US US10/295,799 patent/US20030109515A1/en not_active Abandoned
- 2002-11-22 DE DE60209145T patent/DE60209145T2/de not_active Expired - Lifetime
- 2002-11-22 NZ NZ533383A patent/NZ533383A/en not_active IP Right Cessation
- 2002-11-22 BR BR0214757-2A patent/BR0214757A/pt not_active IP Right Cessation
- 2002-11-22 RS YUP-597/04A patent/RS50360B/sr unknown
- 2002-11-22 HU HU0402217A patent/HUP0402217A3/hu unknown
- 2002-11-22 CA CA002468916A patent/CA2468916C/en not_active Expired - Fee Related
- 2002-11-22 OA OA1200400165A patent/OA12739A/en unknown
- 2002-11-22 IL IL16234802A patent/IL162348A0/xx unknown
- 2002-11-22 AU AU2002352105A patent/AU2002352105B2/en not_active Ceased
- 2002-11-22 ME MEP-104/08A patent/MEP10408A/xx unknown
- 2002-11-22 AT AT02787779T patent/ATE317260T1/de active
- 2002-11-22 EP EP02787779A patent/EP1453517B1/en not_active Expired - Lifetime
- 2002-11-22 KR KR1020047008709A patent/KR100941210B1/ko not_active Expired - Fee Related
- 2002-11-22 SI SI200220035A patent/SI21493A/sl not_active IP Right Cessation
- 2002-11-22 CN CNB028268431A patent/CN100540006C/zh not_active Expired - Fee Related
- 2002-11-22 HR HR20040514A patent/HRP20040514A2/hr not_active Application Discontinuation
- 2002-11-22 JP JP2003548842A patent/JP2005515202A/ja not_active Withdrawn
- 2002-11-22 PT PT02787779T patent/PT1453517E/pt unknown
- 2002-11-22 DK DK02787779T patent/DK1453517T3/da active
- 2002-11-22 MX MXPA04005423A patent/MXPA04005423A/es active IP Right Grant
- 2002-11-22 ES ES02787779T patent/ES2258661T3/es not_active Expired - Lifetime
- 2002-11-22 AP APAP/P/2004/003055A patent/AP1760A/en active
- 2002-11-22 EA EA200400777A patent/EA008090B1/ru not_active IP Right Cessation
- 2002-11-22 GE GE5607A patent/GEP20063895B/en unknown
- 2002-11-22 WO PCT/EP2002/013146 patent/WO2003047587A1/en not_active Ceased
- 2002-11-22 UA UA20040705324A patent/UA77728C2/uk unknown
- 2002-11-22 RO ROA200400514A patent/RO121509B1/ro unknown
- 2002-11-22 PL PL370254A patent/PL206755B1/pl not_active IP Right Cessation
- 2002-12-04 MY MYPI20024553A patent/MY134422A/en unknown
- 2002-12-04 AR ARP020104679A patent/AR037629A1/es unknown
- 2002-12-05 TW TW091135278A patent/TW200409640A/zh unknown
-
2004
- 2004-06-03 IL IL162348A patent/IL162348A/en not_active IP Right Cessation
- 2004-06-03 IS IS7298A patent/IS2580B/is unknown
- 2004-06-04 MA MA27715A patent/MA27153A1/fr unknown
- 2004-06-04 TN TNP2004000104A patent/TNSN04104A1/fr unknown
- 2004-06-04 EC EC2004005140A patent/ECSP045140A/es unknown
- 2004-06-04 CR CR7362A patent/CR7362A/es not_active Application Discontinuation
- 2004-06-07 CO CO04053199A patent/CO5580776A2/es not_active Application Discontinuation
- 2004-06-08 ZA ZA200404525A patent/ZA200404525B/en unknown
- 2004-07-05 NO NO20042842A patent/NO330159B1/no not_active IP Right Cessation
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2006
- 2006-05-04 CY CY20061100574T patent/CY1105608T1/el unknown
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