ECSP055566A - Formulaciones de depósito de corta duración - Google Patents

Formulaciones de depósito de corta duración

Info

Publication number
ECSP055566A
ECSP055566A ECSP055566A ECSP055566A EC SP055566 A ECSP055566 A EC SP055566A EC SP055566 A ECSP055566 A EC SP055566A EC SP055566 A ECSP055566 A EC SP055566A
Authority
EC
Ecuador
Prior art keywords
short
term deposit
deposit formulations
solvent
polymer
Prior art date
Application number
Other languages
English (en)
Inventor
Guohua Chen
David T Priebe
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of ECSP055566A publication Critical patent/ECSP055566A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B18/00—Use of agglomerated or waste materials or refuse as fillers for mortars, concrete or artificial stone; Treatment of agglomerated or waste materials or refuse, specially adapted to enhance their filling properties in mortars, concrete or artificial stone
    • C04B18/04—Waste materials; Refuse
    • C04B18/18—Waste materials; Refuse organic
    • C04B18/20—Waste materials; Refuse organic from macromolecular compounds
    • C04B18/22—Rubber, e.g. ground waste tires
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B28/00—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
    • C04B28/02—Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing hydraulic cements other than calcium sulfates
    • C04B28/04—Portland cements
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B2111/00—Mortars, concrete or artificial stone or mixtures to prepare them, characterised by specific function, property or use
    • C04B2111/40—Porous or lightweight materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02W—CLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO WASTEWATER TREATMENT OR WASTE MANAGEMENT
    • Y02W30/00—Technologies for solid waste management
    • Y02W30/50—Reuse, recycling or recovery technologies
    • Y02W30/91—Use of waste materials as fillers for mortars or concrete

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ceramic Engineering (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Materials Engineering (AREA)
  • Structural Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Civil Engineering (AREA)
  • Environmental & Geological Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invención se refiere a una composición inyectable de depósito, que comprende:(a) un polímero de bajo peso molecular, biocorroible, biocompatible; (b) un solvente que tiene una miscibilidad en agua de menos de, o igual a 7% a 25ºC, en una cantidad efectiva para plasticizar el polímero y formar con ello un gel, donde dicho solvente es un alcohol aromático, y (c) un agente benéfico.
ECSP055566 2002-06-25 2005-01-24 Formulaciones de depósito de corta duración ECSP055566A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39186702P 2002-06-25 2002-06-25

Publications (1)

Publication Number Publication Date
ECSP055566A true ECSP055566A (es) 2005-04-18

Family

ID=30000765

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP055566 ECSP055566A (es) 2002-06-25 2005-01-24 Formulaciones de depósito de corta duración

Country Status (20)

Country Link
EP (3) EP2311431A1 (es)
JP (2) JP2005533081A (es)
KR (1) KR101172721B1 (es)
CN (1) CN1671357B (es)
AR (1) AR039729A1 (es)
AU (1) AU2003245643B2 (es)
BR (1) BR0312033A (es)
CA (1) CA2492047C (es)
EC (1) ECSP055566A (es)
ES (1) ES2530874T3 (es)
IL (1) IL165865A0 (es)
MA (1) MA27371A1 (es)
MX (1) MXPA05000199A (es)
NO (1) NO20050366L (es)
NZ (1) NZ574443A (es)
PL (1) PL207147B1 (es)
RU (1) RU2320321C2 (es)
TW (1) TWI353854B (es)
WO (1) WO2004000269A1 (es)
ZA (1) ZA200500677B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
MXPA05004927A (es) * 2002-11-06 2005-09-08 Alza Corp Formulaciones de deposito de liberacion controlada.
US20050106214A1 (en) * 2003-11-14 2005-05-19 Guohua Chen Excipients in drug delivery vehicles
US8852638B2 (en) 2005-09-30 2014-10-07 Durect Corporation Sustained release small molecule drug formulation
US8658210B2 (en) 2006-04-17 2014-02-25 Advanced Cardiovascular Systems, Inc. Polyesteramide platform for site specific drug delivery
WO2008143992A2 (en) 2007-05-18 2008-11-27 Durect Corporation Improved depot formulations
BRPI0811319A2 (pt) 2007-05-25 2015-02-10 Tolmar Therapeutics Inc Composição fluida, método de formação de uma composição fluida, implante biodegrádavel formado in situ, método de formação de um implante biodegradável in situ, kit, implante e método de trataento
US8846068B2 (en) * 2008-04-18 2014-09-30 Warsaw Orthopedic, Inc. Methods and compositions for treating post-operative pain comprising a local anesthetic
RS60051B1 (sr) * 2011-06-10 2020-04-30 Ramscor Inc Formulacije sa produženim oslobađanjem za isporuku proteina u oko i postupci njihove pripreme
EP2986278A1 (en) 2013-03-11 2016-02-24 DURECT Corporation Injectable controlled release composition comprising high viscosity liquid carrier
US20140308352A1 (en) 2013-03-11 2014-10-16 Zogenix Inc. Compositions and methods involving polymer, solvent, and high viscosity liquid carrier material
US20160303242A1 (en) 2013-12-09 2016-10-20 Durect Corporation Pharmaceutically Active Agent Complexes, Polymer Complexes, and Compositions and Methods Involving the Same
CA3167217A1 (en) 2020-01-13 2021-07-22 Durect Corporation Sustained release drug delivery systems with reduced impurities and related methods
CN111388406B (zh) * 2020-03-24 2024-02-23 西安力邦医药科技有限责任公司 氟维司群或其衍生物可注射递药贮库及其制备方法和应用
CN116940358A (zh) 2021-01-12 2023-10-24 度勒科特公司 持续释放药物递送系统和有关的方法

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3797492A (en) 1972-12-27 1974-03-19 Alza Corp Device for dispensing product with directional guidance member
US3987790A (en) 1975-10-01 1976-10-26 Alza Corporation Osmotically driven fluid dispenser
US4008719A (en) 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
US4443340A (en) 1981-10-09 1984-04-17 Betz Laboratories, Inc. Control of iron induced fouling in water systems
US4985404A (en) 1984-10-04 1991-01-15 Monsanto Company Prolonged release of biologically active polypeptides
US4865845A (en) 1986-03-21 1989-09-12 Alza Corporation Release rate adjustment of osmotic or diffusional delivery devices
US4853218A (en) 1987-02-24 1989-08-01 Schering Corporation Zinc-protamine-alpha interferon complex
US4938763B1 (en) 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
US5085866A (en) 1988-12-02 1992-02-04 Southern Research Institute Method of producing zero-order controlled-released devices
US5057318A (en) 1988-12-13 1991-10-15 Alza Corporation Delivery system for beneficial agent over a broad range of rates
US5059423A (en) 1988-12-13 1991-10-22 Alza Corporation Delivery system comprising biocompatible beneficial agent formulation
US5324519A (en) 1989-07-24 1994-06-28 Atrix Laboratories, Inc. Biodegradable polymer composition
US5112614A (en) 1989-09-14 1992-05-12 Alza Corporation Implantable delivery dispenser
US5234693A (en) 1990-07-11 1993-08-10 Alza Corporation Delivery device with a protective sleeve
US5234692A (en) 1990-07-11 1993-08-10 Alza Corporation Delivery device with a protective sleeve
US5151093A (en) 1990-10-29 1992-09-29 Alza Corporation Osmotically driven syringe with programmable agent delivery
US5620700A (en) 1990-10-30 1997-04-15 Alza Corporation Injectable drug delivery system and method
GB9027422D0 (en) 1990-12-18 1991-02-06 Scras Osmotically driven infusion device
US5137727A (en) 1991-06-12 1992-08-11 Alza Corporation Delivery device providing beneficial agent stability
US5288214A (en) 1991-09-30 1994-02-22 Toshio Fukuda Micropump
FI933471A0 (fi) 1991-12-19 1993-08-05 Mitsui Toatsu Chemicals Polyhydroxikarboxylsyra och foerfarande foer dess framstaellning
WO1993012765A1 (en) * 1991-12-27 1993-07-08 Merck & Co., Inc. A controlled release drug dispersion delivery device
US5308348A (en) 1992-02-18 1994-05-03 Alza Corporation Delivery devices with pulsatile effect
US5209746A (en) 1992-02-18 1993-05-11 Alza Corporation Osmotically driven delivery devices with pulsatile effect
US5456679A (en) 1992-02-18 1995-10-10 Alza Corporation Delivery devices with pulsatile effect
US5656297A (en) 1992-03-12 1997-08-12 Alkermes Controlled Therapeutics, Incorporated Modulated release from biocompatible polymers
GB9211268D0 (en) * 1992-05-28 1992-07-15 Ici Plc Salts of basic peptides with carboxyterminated polyesters
US5242910A (en) 1992-10-13 1993-09-07 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
DK0674506T3 (da) 1992-12-02 2001-01-08 Alkermes Inc Væksthormonholdige mikrosfærer med styret frigivelse
US5556905A (en) 1994-03-30 1996-09-17 Reilly Industries, Inc. Physically-modified degradable thermoplastic compositions
ES2258495T3 (es) 1994-04-08 2006-09-01 Qlt Usa, Inc. Composiciones de administracion liquida de farmacos.
US5626862A (en) 1994-08-02 1997-05-06 Massachusetts Institute Of Technology Controlled local delivery of chemotherapeutic agents for treating solid tumors
US5968895A (en) * 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
JP2002512597A (ja) * 1996-12-20 2002-04-23 アルザ コーポレイション 注射可能な貯留槽ゲル組成物およびこの組成物の製造方法
US6841617B2 (en) * 2000-09-28 2005-01-11 Battelle Memorial Institute Thermogelling biodegradable aqueous polymer solution
NZ515911A (en) * 1999-06-04 2004-02-27 Alza Corp Implantable gel compositions and method of manufacture
ATE407676T1 (de) * 2000-02-28 2008-09-15 Univ British Columbia Topoisomerasehemmern zur behandlung von chirurgischen verklebungen
CN1283215C (zh) * 2000-06-28 2006-11-08 A·J·舒克拉 生物活性物质的可生物降解载体和释放系统
US7194507B2 (en) * 2000-06-29 2007-03-20 Ntt Docomo, Inc. Method and apparatus for setting communication parameter in information terminal
WO2002038185A2 (en) * 2000-11-13 2002-05-16 Atrix Laboratories, Inc. Injectable sustained release delivery system with loperamide
DE60231862D1 (de) * 2001-02-23 2009-05-20 Genentech Inc Erodierbare polymere zur injektion
WO2003041757A2 (en) * 2001-11-14 2003-05-22 Alza Corporation Catheter injectable depot compositions and uses thereof
CA2466632C (en) * 2001-11-14 2014-02-11 Alza Corporation Injectable depot compositions and uses thereof

Also Published As

Publication number Publication date
IL165865A0 (en) 2006-01-15
RU2320321C2 (ru) 2008-03-27
JP5631708B2 (ja) 2014-11-26
HK1082412A1 (en) 2006-06-09
JP2011068670A (ja) 2011-04-07
AU2003245643A1 (en) 2004-01-06
MXPA05000199A (es) 2005-06-06
CN1671357A (zh) 2005-09-21
CN1671357B (zh) 2010-08-11
PL373123A1 (en) 2005-08-08
AR039729A1 (es) 2005-03-09
BR0312033A (pt) 2005-04-26
AU2003245643B2 (en) 2009-02-26
MA27371A1 (fr) 2005-06-01
EP1515697B1 (en) 2014-11-19
KR101172721B1 (ko) 2012-08-30
NZ574443A (en) 2010-08-27
CA2492047A1 (en) 2003-12-31
KR20050026414A (ko) 2005-03-15
TW200404578A (en) 2004-04-01
EP2316421A1 (en) 2011-05-04
JP2005533081A (ja) 2005-11-04
WO2004000269A1 (en) 2003-12-31
EP2311431A1 (en) 2011-04-20
EP1515697A1 (en) 2005-03-23
PL207147B1 (pl) 2010-11-30
TWI353854B (en) 2011-12-11
NO20050366L (no) 2005-03-23
ES2530874T3 (es) 2015-03-06
ZA200500677B (en) 2006-08-30
CA2492047C (en) 2014-08-12
RU2005101640A (ru) 2005-08-10

Similar Documents

Publication Publication Date Title
BR0317822A (pt) Composição fluoroquìmica
BR0316310A (pt) Composições farmacêuticas tendo um veìculo modificado
DK1162943T3 (da) Ikke-sviende coatingpræparat
BR0206984A (pt) Composições de depósito injetáveis e uso destas
BR9810291A (pt) Composições antitranspirantes em bastão de gel sólido com baixa formação residual contendo solventes de hidrocarboneto não-polares voláteis
ES2079943T3 (es) Composiciones acuosas en aerosol para la pulverizacion del cabello que tienen un contenido relativamente bajo en compuestos organicos volatiles.
BRPI0511966A (pt) composições farmacêuticas contendo polietileno glicol tendo um peso molecular menor do que 600 daltons
ATE392886T1 (de) Injizierbare depotzusammensetzungen und deren verwendung
AR054637A1 (es) Aerosoles y composiciones hemostaticas
AR035415A1 (es) Composiciones de fluidos para tratamiento de pozos y metodos para su uso
MXPA00012959A (es) Combinacion de composiciones de silicio con llenador.
NO20033178D0 (no) Kateterinjiserbare depotforbindelser og deres anvendelse
PE24591A1 (es) Composicion cosmetica
UY25055A1 (es) Formulaciones farmacéuticas que contienen voriconazol
BRPI0414461A (pt) microgéis em meio orgánico não-reticulável
BRPI0500968A (pt) Emulsificador
EP1219289A3 (en) Cosmetic compositions containing silicone gel
AR052069A1 (es) Composiciones detergentes liquidas substancialmente no acuosas y su utilizacion
BRPI0601896A (pt) composições que contêm microgéis e agentes espessantes
ES2163457T3 (es) Composiciones de revestimiento que comprenden 1,4-ciclohexano dimetanol.
BR0006810A (pt) Composição compreendendo um amido, e, fibra oufilamento compreendendo amido
PA8584101A1 (es) Composicion antihelmintica e inyectable mejoradora de crecimiento
CO4920220A1 (es) Composiciones que contienen compuestos fluoroeter y metodos para inhibir su degradacion en presencia de un acido de lewis
ES2175825T3 (es) Antitraspirante con dibencilidensorbitol.
PE20030402A1 (es) Productos para la axila con componentes de bloqueo de agua