ECSP055682A - NEW OXAZOL AND TIAZOL COMPOUNDS AS INHIBITORS OF THE TRANSFORMING GROWTH FACTOR (TGF) - Google Patents

NEW OXAZOL AND TIAZOL COMPOUNDS AS INHIBITORS OF THE TRANSFORMING GROWTH FACTOR (TGF)

Info

Publication number
ECSP055682A
ECSP055682A ECSP055682A ECSP055682A EC SP055682 A ECSP055682 A EC SP055682A EC SP055682 A ECSP055682 A EC SP055682A EC SP055682 A ECSP055682 A EC SP055682A
Authority
EC
Ecuador
Prior art keywords
tgf
compounds
growth factor
transforming growth
new
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Laura Cook Blumberg
Michael John Munchhof
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ECSP055682A publication Critical patent/ECSP055682A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

. Se describen nuevos compuestos de oxazol y tiazol, incluyendo derivados de los mismos, intermedios para prepararlos, composiciones farmacéuticas que los contienen y su uso medicinal. Los compuestos de la presente invención son potentes inhibidores de la ruta de señalización del factor de crecimiento transformador ("TGF")-ß. Son útiles en el tratamiento de diversas patologías relacionadas con TGF incluyendo, por ejemplo, cáncer y enfermedades fibróticas. New oxazole and thiazole compounds, including derivatives thereof, intermediates for preparing them, pharmaceutical compositions containing them and their medicinal use are described. The compounds of the present invention are potent inhibitors of the signaling pathway of the transforming growth factor ("TGF") - ß. They are useful in the treatment of various pathologies related to TGF including, for example, cancer and fibrotic diseases

ECSP055682 2002-09-18 2005-03-17 NEW OXAZOL AND TIAZOL COMPOUNDS AS INHIBITORS OF THE TRANSFORMING GROWTH FACTOR (TGF) ECSP055682A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41212002P 2002-09-18 2002-09-18
US48458103P 2003-07-02 2003-07-02

Publications (1)

Publication Number Publication Date
ECSP055682A true ECSP055682A (en) 2005-05-30

Family

ID=40202989

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP055682 ECSP055682A (en) 2002-09-18 2005-03-17 NEW OXAZOL AND TIAZOL COMPOUNDS AS INHIBITORS OF THE TRANSFORMING GROWTH FACTOR (TGF)

Country Status (1)

Country Link
EC (1) ECSP055682A (en)

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