ECSP056043A - Compuestos cristalinos de n-formil hidroxilamina - Google Patents

Compuestos cristalinos de n-formil hidroxilamina

Info

Publication number
ECSP056043A
ECSP056043A EC2005006043A ECSP056043A ECSP056043A EC SP056043 A ECSP056043 A EC SP056043A EC 2005006043 A EC2005006043 A EC 2005006043A EC SP056043 A ECSP056043 A EC SP056043A EC SP056043 A ECSP056043 A EC SP056043A
Authority
EC
Ecuador
Prior art keywords
hydroxylamine
formil
crystal compounds
7alkanes
compounds
Prior art date
Application number
EC2005006043A
Other languages
English (en)
Inventor
Joel Slade
Martin Mueller
Hui Liu
Joginder Singh Bajwa
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33131903&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP056043(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ECSP056043A publication Critical patent/ECSP056043A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Se describen ciertos compuestos de N-formil hidroxilamina, tales como N-[1-oxo-2-alquil-3-(N-hidroxiformamido)-propil]-(carbonilamino-aril o -heteroaril)-azaciclo4-7alcanos o tiazaciclo4-7alcanos o imidazaciclo4-7alcanos, que son útiles en el tratamiento de infecciones bacterianas. También se describen sales cristalinas de dichos compuestos de la fórmula (I), en donde M es un metal mono- o di-valente; a es ½ o 1.
EC2005006043A 2003-04-02 2005-09-28 Compuestos cristalinos de n-formil hidroxilamina ECSP056043A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45972603P 2003-04-02 2003-04-02

Publications (1)

Publication Number Publication Date
ECSP056043A true ECSP056043A (es) 2006-01-27

Family

ID=33131903

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2005006043A ECSP056043A (es) 2003-04-02 2005-09-28 Compuestos cristalinos de n-formil hidroxilamina

Country Status (25)

Country Link
US (1) US20070135353A1 (es)
EP (1) EP1613305A1 (es)
JP (1) JP2006522054A (es)
KR (1) KR20060002915A (es)
CN (1) CN1764450A (es)
AR (1) AR043804A1 (es)
AU (1) AU2004226815B2 (es)
BR (1) BRPI0409009A (es)
CA (1) CA2520682A1 (es)
CL (1) CL2004000705A1 (es)
CO (1) CO5630028A2 (es)
EC (1) ECSP056043A (es)
IS (1) IS8093A (es)
MA (1) MA27763A1 (es)
MX (1) MXPA05010610A (es)
MY (1) MY136854A (es)
NO (1) NO20055097L (es)
NZ (1) NZ542432A (es)
PE (1) PE20050392A1 (es)
RU (1) RU2005133660A (es)
SG (1) SG166681A1 (es)
TN (1) TNSN05248A1 (es)
TW (1) TW200427458A (es)
WO (1) WO2004087133A1 (es)
ZA (1) ZA200507179B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1406893B1 (en) 2001-06-15 2007-04-18 Vicuron Pharmaceuticals, Inc. Pyrrolidine bicyclic compounds
ES2321504T3 (es) 2002-09-19 2009-06-08 Novartis Ag Proceso para la preparacion de productos intermedios.
AU2004216178B2 (en) 2003-02-21 2008-07-03 Novartis Ag Chemical process for the preparation of intermediates to obtain N-formyl hydroxylamine compounds
GT200600196A (es) * 2005-05-23 2007-01-15 Compuestos n-formil de hidroxilamina
US10738028B2 (en) 2016-05-11 2020-08-11 Rudong Ruien Pharmaceutical Technology Co. Ltd Spiro three-membered ring, spiro five-membered ring peptide deformylase inhibitor and use thereof in antibacteria and anti-tumor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3282986A (en) * 1960-10-06 1966-11-01 Merck & Co Inc N-acylated hydroxamic acids and derivatives thereof
EP1052984B1 (en) * 1998-02-07 2004-05-12 Vernalis (Oxford) Ltd Antibacterial agents
AR036053A1 (es) * 2001-06-15 2004-08-04 Versicor Inc Compuestos de n-formil-hidroxilamina, un proceso para su preparacion y composiciones farmaceuticas

Also Published As

Publication number Publication date
AU2004226815B2 (en) 2007-07-19
AR043804A1 (es) 2005-08-10
IS8093A (is) 2005-10-27
MXPA05010610A (es) 2005-11-23
RU2005133660A (ru) 2006-06-10
NO20055097L (no) 2005-12-22
ZA200507179B (en) 2006-04-26
AU2004226815A1 (en) 2004-10-14
CA2520682A1 (en) 2004-10-14
WO2004087133A1 (en) 2004-10-14
TW200427458A (en) 2004-12-16
TNSN05248A1 (en) 2007-06-11
CN1764450A (zh) 2006-04-26
JP2006522054A (ja) 2006-09-28
PE20050392A1 (es) 2005-06-19
KR20060002915A (ko) 2006-01-09
SG166681A1 (en) 2010-12-29
CO5630028A2 (es) 2006-04-28
MY136854A (en) 2008-11-28
EP1613305A1 (en) 2006-01-11
MA27763A1 (fr) 2006-02-01
CL2004000705A1 (es) 2005-01-14
US20070135353A1 (en) 2007-06-14
NO20055097D0 (no) 2005-11-01
NZ542432A (en) 2009-04-30
BRPI0409009A (pt) 2006-03-28

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