ECSP056043A - Compuestos cristalinos de n-formil hidroxilamina - Google Patents

Compuestos cristalinos de n-formil hidroxilamina

Info

Publication number
ECSP056043A
ECSP056043A EC2005006043A ECSP056043A ECSP056043A EC SP056043 A ECSP056043 A EC SP056043A EC 2005006043 A EC2005006043 A EC 2005006043A EC SP056043 A ECSP056043 A EC SP056043A EC SP056043 A ECSP056043 A EC SP056043A
Authority
EC
Ecuador
Prior art keywords
hydroxylamine
formil
crystal compounds
7alkanes
compounds
Prior art date
Application number
EC2005006043A
Other languages
English (en)
Inventor
Joel Slade
Martin Mueller
Hui Liu
Joginder Singh Bajwa
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33131903&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP056043(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ECSP056043A publication Critical patent/ECSP056043A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se describen ciertos compuestos de N-formil hidroxilamina, tales como N-[1-oxo-2-alquil-3-(N-hidroxiformamido)-propil]-(carbonilamino-aril o -heteroaril)-azaciclo4-7alcanos o tiazaciclo4-7alcanos o imidazaciclo4-7alcanos, que son útiles en el tratamiento de infecciones bacterianas. También se describen sales cristalinas de dichos compuestos de la fórmula (I), en donde M es un metal mono- o di-valente; a es ½ o 1.
EC2005006043A 2003-04-02 2005-09-28 Compuestos cristalinos de n-formil hidroxilamina ECSP056043A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45972603P 2003-04-02 2003-04-02

Publications (1)

Publication Number Publication Date
ECSP056043A true ECSP056043A (es) 2006-01-27

Family

ID=33131903

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2005006043A ECSP056043A (es) 2003-04-02 2005-09-28 Compuestos cristalinos de n-formil hidroxilamina

Country Status (25)

Country Link
US (1) US20070135353A1 (es)
EP (1) EP1613305A1 (es)
JP (1) JP2006522054A (es)
KR (1) KR20060002915A (es)
CN (1) CN1764450A (es)
AR (1) AR043804A1 (es)
AU (1) AU2004226815B2 (es)
BR (1) BRPI0409009A (es)
CA (1) CA2520682A1 (es)
CL (1) CL2004000705A1 (es)
CO (1) CO5630028A2 (es)
EC (1) ECSP056043A (es)
IS (1) IS8093A (es)
MA (1) MA27763A1 (es)
MX (1) MXPA05010610A (es)
MY (1) MY136854A (es)
NO (1) NO20055097L (es)
NZ (1) NZ542432A (es)
PE (1) PE20050392A1 (es)
RU (1) RU2005133660A (es)
SG (1) SG166681A1 (es)
TN (1) TNSN05248A1 (es)
TW (1) TW200427458A (es)
WO (1) WO2004087133A1 (es)
ZA (1) ZA200507179B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1406893T3 (da) 2001-06-15 2007-08-06 Vicuron Pharm Inc Bicykliske pyrrolidinforbindelser
WO2004026824A1 (en) 2002-09-19 2004-04-01 Novartis Ag Process for preparing intermediates
PL379008A1 (pl) 2003-02-21 2006-06-26 Novartis Ag Chemiczny sposób wytwarzania związków pośrednich do otrzymywania związków N-formylohydroksyloaminowych
GT200600196A (es) * 2005-05-23 2007-01-15 Compuestos n-formil de hidroxilamina
JP7001898B2 (ja) * 2016-05-11 2022-01-20 グアンドン・ヘボ・ファーマシューティカル・カンパニー・リミテッド スピロ３員環、スピロ５員環系ペプチドデホルミラーゼ阻害剤および抗菌と抗腫瘍におけるその使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3282986A (en) * 1960-10-06 1966-11-01 Merck & Co Inc N-acylated hydroxamic acids and derivatives thereof
PL194240B1 (pl) * 1998-02-07 2007-05-31 British Biotech Pharm Zastosowanie pochodnych N-formylohydroksyloaminy i amidowa pochodna N-formylohydroksyloaminy
AR036053A1 (es) * 2001-06-15 2004-08-04 Versicor Inc Compuestos de n-formil-hidroxilamina, un proceso para su preparacion y composiciones farmaceuticas

Also Published As

Publication number Publication date
MY136854A (en) 2008-11-28
MA27763A1 (fr) 2006-02-01
JP2006522054A (ja) 2006-09-28
US20070135353A1 (en) 2007-06-14
ZA200507179B (en) 2006-04-26
WO2004087133A1 (en) 2004-10-14
CN1764450A (zh) 2006-04-26
BRPI0409009A (pt) 2006-03-28
PE20050392A1 (es) 2005-06-19
EP1613305A1 (en) 2006-01-11
NO20055097D0 (no) 2005-11-01
AU2004226815A1 (en) 2004-10-14
KR20060002915A (ko) 2006-01-09
AR043804A1 (es) 2005-08-10
IS8093A (is) 2005-10-27
NZ542432A (en) 2009-04-30
CO5630028A2 (es) 2006-04-28
AU2004226815B2 (en) 2007-07-19
TNSN05248A1 (en) 2007-06-11
TW200427458A (en) 2004-12-16
SG166681A1 (en) 2010-12-29
CA2520682A1 (en) 2004-10-14
MXPA05010610A (es) 2005-11-23
CL2004000705A1 (es) 2005-01-14
NO20055097L (no) 2005-12-22
RU2005133660A (ru) 2006-06-10

Similar Documents

Publication Publication Date Title
NO20070606L (no) Inhibitorer av IAP
ATE368031T1 (de) Neue gamma secretase inhibitoren
MXPA05012323A (es) Sulfonamidas ciclicas para la inhibicion de gama-secretasa.
ATE433981T1 (de) Heterocyclische verbindungen
CL2004000076A1 (es) Compuestos derivados de indol, inhibidores de polimerasa, sales; composicion farmaceutica que los comprende; procedimiento de preparacion de dichos compuestos; compuestos intermediarios; y uso del compuesto para tratar una infeccion causada por el vi
DE60334536D1 (de) Furylverbindungen
ATE433447T1 (de) Pyrimiidinverbindungen
NO20073783L (no) Pyrrolidininhibitorer for IAP
DE60329533D1 (de) Cyclische sulfamide zur inhibierung von gamma-sekretase
ATE466856T1 (de) Verbindungen und methoden zum behandeln oder vorbeugen von flavivirus infektionen
CO5570678A2 (es) N-alquilo-4-metileneamino-3-hidroxilo-2-piridonas como anti- microbianos
NO20040100L (no) Nye forbindelser som anti-inflammasjons, immunmodulerende og anti-proliferative midler
CY1107688T1 (el) Δικυκλικες ενωσεις πυρρολιδινης
SE0400043D0 (sv) New compounds
MY138619A (en) N-formyl hydroxylamine compounds
EA200801607A1 (ru) Производные бензимидазолонкарбоновой кислоты
SE0403171D0 (sv) New compounds
HRP20090159T1 (en) Use of glucosidase inhibitors for therapy of mucovisidosis
NO20054361D0 (no) Benzensylfonamidderivater, fremgangsmate for fremstilling og anvendelse derav for behandlig av smerte
HRP20050517B1 (hr) N-sulfonil-4-metilenamino-3-hidroksi-2-piridoni kao antimikrobni lijekovi
DE602004018162D1 (de) hERG1-KANAL-ÖFFNER ZUR BEHANDLUNG VON HERZARRYTHMIEN
SE0002739D0 (sv) New use
NO20060718L (no) Substituerte tiofoner og deres anvendelse
TNSN05248A1 (en) Crystalline n-formyl hydroxylamine compounds
NO20081103L (no) 9-Aminoklarbonylsubstituerte derivater av glycylcykliner