ECSP056078A - Composición de insulina inyectable de acción prolongada y métodos de fabricación y uso del mismo - Google Patents

Composición de insulina inyectable de acción prolongada y métodos de fabricación y uso del mismo

Info

Publication number
ECSP056078A
ECSP056078A EC2005006078A ECSP056078A ECSP056078A EC SP056078 A ECSP056078 A EC SP056078A EC 2005006078 A EC2005006078 A EC 2005006078A EC SP056078 A ECSP056078 A EC SP056078A EC SP056078 A ECSP056078 A EC SP056078A
Authority
EC
Ecuador
Prior art keywords
composition
manufacture
methods
prolonged action
insulin
Prior art date
Application number
EC2005006078A
Other languages
English (en)
Inventor
Vladimir Sabetsky
Original Assignee
Technology Dev Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technology Dev Company filed Critical Technology Dev Company
Publication of ECSP056078A publication Critical patent/ECSP056078A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

Un método para reducir la glucosa sanguínea en un mamífero incluye inyectar una cantidad terapéuticamente efectiva de micropartículas de dextrán cristalizada e insulina al mamífero para reducir la glucosa sanguínea del mamífero. La composición puede ser una fase o una composición multi-fase estructurada para liberación controlada de insulina durante un periodo de tiempo extendido.
EC2005006078A 2003-03-04 2005-10-04 Composición de insulina inyectable de acción prolongada y métodos de fabricación y uso del mismo ECSP056078A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US45124503P 2003-03-04 2003-03-04
US46760103P 2003-05-05 2003-05-05
US46901703P 2003-05-09 2003-05-09
US49509703P 2003-08-15 2003-08-15

Publications (1)

Publication Number Publication Date
ECSP056078A true ECSP056078A (es) 2006-08-30

Family

ID=32831112

Family Applications (3)

Application Number Title Priority Date Filing Date
EC2005006078A ECSP056078A (es) 2003-03-04 2005-10-04 Composición de insulina inyectable de acción prolongada y métodos de fabricación y uso del mismo
EC2005006077A ECSP056077A (es) 2003-03-04 2005-10-04 Composición de insulina oral y métodos de fabricación y uso de estos
EC2005006076A ECSP056076A (es) 2003-03-04 2005-10-04 Sistema de suministro para droga y terapia celular

Family Applications After (2)

Application Number Title Priority Date Filing Date
EC2005006077A ECSP056077A (es) 2003-03-04 2005-10-04 Composición de insulina oral y métodos de fabricación y uso de estos
EC2005006076A ECSP056076A (es) 2003-03-04 2005-10-04 Sistema de suministro para droga y terapia celular

Country Status (17)

Country Link
US (5) US20040234615A1 (es)
EP (3) EP1603589A1 (es)
JP (3) JP2006519252A (es)
KR (3) KR20060015469A (es)
AR (1) AR046485A1 (es)
AT (1) ATE485051T1 (es)
AU (3) AU2004216908A1 (es)
BR (3) BRPI0408105A (es)
CA (3) CA2518136A1 (es)
DE (1) DE602004029630D1 (es)
EA (3) EA200501422A1 (es)
EC (3) ECSP056078A (es)
MX (1) MXPA05009493A (es)
NO (3) NO20054533L (es)
PT (1) PT1454630E (es)
TW (1) TW200529869A (es)
WO (3) WO2004078198A1 (es)

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KR20200108392A (ko) 2020-08-31 2020-09-18 김용원 전동 오토바이 모터의 정격에 맞는 오토바이바퀴에 회전자와 물받이 고정자 발전기를 설치한 오토바이에 모터가 장착된 항공기 공기추진기(Propulsor)와 장착한 드론의 프로퓰러(Propullor)를 장착하는 제조기술)
WO2022149125A1 (en) * 2021-01-07 2022-07-14 Ramot At Tel Aviv University Ltd. Methods and compositions for melanin synthesis
KR20210018367A (ko) 2021-01-26 2021-02-17 김용원 전동 오토바이에 설치한 모터가 장착된 항공기 공기추진기와 장착한 프로퓰러(Propullor)로 구성한 오토에어크라프트(Autoaircraft)
KR20210029730A (ko) 2021-02-22 2021-03-16 김용원 산사태에 대비, 대응하는 에어 레이어들 블록들이 형성된 거대장비들(에어 레이어들 블록들)
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KR20210045369A (ko) 2021-03-31 2021-04-26 김용원 전기 에어 카
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KR20210055643A (ko) 2021-04-27 2021-05-17 김용원 모터가 장착된 회전축에 다량의 회전자바퀴와 다량의 고정자바퀴발전기를 설치한 전동보드
KR20210072739A (ko) 2021-05-27 2021-06-17 김용원 의료용 전동보드
KR20210080293A (ko) 2021-06-11 2021-06-30 김용원 바퀴 사이 발전기 케이스
CN115702880B (zh) * 2021-08-12 2023-11-03 山东新时代药业有限公司 一种重组甘精胰岛素注射液及其制备工艺
KR20220016234A (ko) 2022-01-14 2022-02-08 김용원 공기추진기(공기펌프와 공기터빈)를 장착한 3륜 자전거
KR20220038026A (ko) 2022-02-24 2022-03-25 김용원 4합 공기터빈 : 공기터빈 축에 1. 인너 팬들의 인너 실린더와 2. 아웃터 팬들의 아웃터 실린더와 3. 양쪽 1. 인너 실린더들과 2. 아웃터 실린더들의 사이에 아웃터 팬들에 덕트팬들과 덕트흡입구와 4 1. 인너 실린더들과 2. 아웃터 실린더들의 사이에 아웃터 팬들의 3. 덕트팬들에 블레이드와 블레이드 외부 형틀
KR20220056159A (ko) 2022-04-04 2022-05-04 김용원 물탱크 내의 스팀집 슈퍼히터에 전력공급한 스팀공급으로 스팀터빈을 구동하는 것과 슈퍼히터로 스팀을 공급하는 스팀청소기에 발전기들을 설치하는 것과 공기터빈의 흡입구들의 공기필터들 설치와 펠티에소자를 이용한 냉온 공기배출과 얼음제조기 시스템
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KR20220080053A (ko) 2022-05-27 2022-06-14 김용원 다중 에어 레이어 튜브보트
KR20240124226A (ko) * 2023-02-08 2024-08-16 주식회사 인벤테라 체내 구조물 사이에서 응집없이 압축가능한 다당류 가교 콜로이드 입자 및 이의 생체내 주입용 개질제로서의 용도
KR20250070006A (ko) 2025-04-23 2025-05-20 김용원 수륙양용 전동보드

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