ECSP066647A - Derivados de triazol como antagonistas de vasopresina - Google Patents

Derivados de triazol como antagonistas de vasopresina

Info

Publication number: ECSP066647A
Authority: EC; Ecuador
Prior art keywords: saturated; optionally substituted; heterocyclic ring; ring; number chosen
Prior art date: 2003-12-22

Application number

EC2006006647A

Other languages

English (en)

Spanish (es)

Inventor

Patrick Stephen Johnson

Thomas Ryckmans

Lee Richard Roberts

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-12-22

Filing date

2006-06-15

Publication date

2006-10-25

2003-12-22 Priority claimed from GB0329693A external-priority patent/GB0329693D0/en

2004-04-20 Priority claimed from GB0408789A external-priority patent/GB0408789D0/en

2006-06-15 Application filed by Pfizer filed Critical Pfizer

2006-10-25 Publication of ECSP066647A publication Critical patent/ECSP066647A/es

Links

239000005557 antagonist Substances 0.000 title abstract 2
QWENRTYMTSOGBR-UHFFFAOYSA-N 1H-1,2,3-Triazole Chemical class C=1C=NNN=1 QWENRTYMTSOGBR-UHFFFAOYSA-N 0.000 title 1
229920006395 saturated elastomer Polymers 0.000 abstract 8
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 3
UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
125000006615 aromatic heterocyclic group Chemical group 0.000 abstract 3
125000000623 heterocyclic group Chemical group 0.000 abstract 3
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
125000006552 (C3-C8) cycloalkyl group Chemical group 0.000 abstract 2
101100070530 Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) het-6 gene Proteins 0.000 abstract 2
125000003118 aryl group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 1
125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
208000005171 Dysmenorrhea Diseases 0.000 abstract 1
206010013935 Dysmenorrhoea Diseases 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000000843 phenylene group Chemical group C1(=C(C=CC=C1)*)* 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
- A—HUMAN NECESSITIES
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- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Cardiology (AREA)
Diabetes (AREA)
Reproductive Health (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Ophthalmology & Optometry (AREA)
Hematology (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Gynecology & Obstetrics (AREA)
Vascular Medicine (AREA)
Pregnancy & Childbirth (AREA)
Obesity (AREA)
Psychiatry (AREA)
Rheumatology (AREA)
Anesthesiology (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Emergency Medicine (AREA)

EC2006006647A 2003-12-22 2006-06-15 Derivados de triazol como antagonistas de vasopresina ECSP066647A (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB0329693A GB0329693D0 (en)	2003-12-22	2003-12-22	Compounds useful in therapy
GB0408789A GB0408789D0 (en)	2004-04-20	2004-04-20	Triazole derivatives

Publications (1)

Publication Number	Publication Date
ECSP066647A true ECSP066647A (es)	2006-10-25

Family

ID=34740750

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EC2006006647A ECSP066647A (es)	2003-12-22	2006-06-15	Derivados de triazol como antagonistas de vasopresina

Country Status (24)

Country	Link
EP (1)	EP1701959A1 (is)
JP (1)	JP4698604B2 (is)
KR (1)	KR100854872B1 (is)
AP (1)	AP2331A (is)
AR (1)	AR047340A1 (is)
AU (1)	AU2004309164B2 (is)
BR (1)	BRPI0417267A (is)
CA (1)	CA2551038C (is)
CR (1)	CR8481A (is)
DO (1)	DOP2004001062A (is)
EA (1)	EA010132B1 (is)
EC (1)	ECSP066647A (is)
GE (1)	GEP20084571B (is)
IL (1)	IL176349A (is)
IS (1)	IS8472A (is)
MA (1)	MA28393B1 (is)
NL (1)	NL1027833C2 (is)
NO (1)	NO20063380L (is)
OA (1)	OA13347A (is)
PA (1)	PA8620501A1 (is)
PE (1)	PE20051051A1 (is)
TW (1)	TWI287541B (is)
UY (1)	UY28693A1 (is)
WO (1)	WO2005063754A1 (is)

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TW200626138A (en)	2004-09-20	2006-08-01	Xenon Pharmaceuticals Inc	Heterocyclic derivatives and their use as therapeutic agents
AR051026A1 (es)	2004-09-20	2006-12-13	Xenon Pharmaceuticals Inc	Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
WO2006034341A2 (en)	2004-09-20	2006-03-30	Xenon Pharmaceuticals Inc.	Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase
US8071603B2 (en)	2004-09-20	2011-12-06	Xenon Pharmaceuticals Inc.	Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
BRPI0515482A (pt)	2004-09-20	2008-07-22	Xenon Pharmaceuticals Inc	derivados heterocìclicos e seus usos como agentes terapêuticos
CA2580855A1 (en) *	2004-09-20	2006-03-30	Xenon Pharmaceuticals Inc.	Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
AU2005297966B2 (en)	2004-10-26	2010-12-23	Eisai R & D Management Co., Ltd.	Amorphous object of cinnamide compound
AP2007004047A0 (en)	2005-01-20	2007-06-30	Pfizer Ltd	Substituted triazole derivatives as oxtocin antagonists
US8541457B2 (en)	2005-06-03	2013-09-24	Xenon Pharmaceuticals Inc.	Aminothiazole derivatives as human stearoyl-CoA desaturase inhibitors
CN102295636A (zh) *	2005-07-29	2011-12-28	弗·哈夫曼-拉罗切有限公司	吲哚-3-基-羰基-哌啶和哌嗪衍生物
TWI370130B (en)	2005-11-24	2012-08-11	Eisai R&D Man Co Ltd	Two cyclic cinnamide compound
TWI378091B (en)	2006-03-09	2012-12-01	Eisai R&D Man Co Ltd	Multi-cyclic cinnamide derivatives
WO2008013622A2 (en)	2006-07-27	2008-01-31	E. I. Du Pont De Nemours And Company	Fungicidal azocyclic amides
US9090604B2 (en)	2006-07-27	2015-07-28	E I Du Pont De Nemours And Company	Fungicidal azocyclic amides
US7737141B2 (en)	2006-07-28	2010-06-15	Eisai R&D Management Co., Ltd.	Prodrug of cinnamide compound
ATE469899T1 (de) *	2006-12-07	2010-06-15	Hoffmann La Roche	Spiropiperidinderivate
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2004
- 2004-12-09 BR BRPI0417267-1A patent/BRPI0417267A/pt active Search and Examination
- 2004-12-09 KR KR1020067012328A patent/KR100854872B1/ko not_active Expired - Fee Related
- 2004-12-09 EP EP04801354A patent/EP1701959A1/en not_active Withdrawn
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- 2006-06-15 IL IL176349A patent/IL176349A/en not_active IP Right Cessation
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Also Published As

Publication number	Publication date
EA200600925A1 (ru)	2006-12-29
KR100854872B1 (ko)	2008-08-28
JP2007515468A (ja)	2007-06-14
PE20051051A1 (es)	2005-12-17
BRPI0417267A (pt)	2007-04-17
DOP2004001062A (es)	2005-06-30
TW200528099A (en)	2005-09-01
IL176349A0 (en)	2006-10-05
KR20060101546A (ko)	2006-09-25
AR047340A1 (es)	2006-01-18
NO20063380L (no)	2006-09-22
WO2005063754A1 (en)	2005-07-14
UY28693A1 (es)	2005-07-29
EP1701959A1 (en)	2006-09-20
CR8481A (es)	2007-12-04
AP2006003631A0 (en)	2006-06-30
AU2004309164B2 (en)	2007-11-15
OA13347A (en)	2007-04-13
CA2551038A1 (en)	2005-07-14
JP4698604B2 (ja)	2011-06-08
NL1027833C2 (nl)	2006-03-06
AP2331A (en)	2011-12-05
GEP20084571B (en)	2008-12-25
EA010132B1 (ru)	2008-06-30
IS8472A (is)	2006-05-18
CA2551038C (en)	2010-04-27
IL176349A (en)	2011-11-30
PA8620501A1 (es)	2005-08-04
MA28393B1 (fr)	2007-01-02
HK1095822A1 (en)	2007-07-06
NL1027833A1 (nl)	2005-06-23
TWI287541B (en)	2007-10-01
AU2004309164A1 (en)	2005-07-14

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