ECSP066722A - - Google Patents
Info
- Publication number
- ECSP066722A ECSP066722A EC2006006722A ECSP066722A ECSP066722A EC SP066722 A ECSP066722 A EC SP066722A EC 2006006722 A EC2006006722 A EC 2006006722A EC SP066722 A ECSP066722 A EC SP066722A EC SP066722 A ECSP066722 A EC SP066722A
- Authority
- EC
- Ecuador
- Prior art keywords
- sensory neuropathy
- polynucleotides
- polypeptides
- neuropathies
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
La invención se refiere a anticuerpos anti trkC agonistas, polipéptidos y polinucleótidos que los codifican. La invención además se refiere al uso de tales anticuerpos, polipéptidos y/o polinucleótidos en el tratamiento y/o prevención de neuropatías tales como, neuropatías sensoriales, incluyendo neuropatía sensorial inducida por taxol, neuropatía sensorial inducida por cisplatina, y neuropatía sensorial inducida por piridoxina.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53259203P | 2003-12-23 | 2003-12-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP066722A true ECSP066722A (es) | 2006-11-24 |
Family
ID=34738811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2006006722A ECSP066722A (es) | 2003-12-23 | 2006-07-21 |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US7968690B2 (es) |
| EP (2) | EP2402756A3 (es) |
| JP (1) | JP4503617B2 (es) |
| KR (1) | KR20070001932A (es) |
| CN (1) | CN1947012A (es) |
| AP (1) | AP2006003670A0 (es) |
| AU (1) | AU2004308482A1 (es) |
| BR (1) | BRPI0417270A (es) |
| CA (1) | CA2551097A1 (es) |
| CR (1) | CR8525A (es) |
| EA (1) | EA200601220A1 (es) |
| EC (1) | ECSP066722A (es) |
| IL (1) | IL176485A0 (es) |
| MA (1) | MA28395B1 (es) |
| NO (1) | NO20063375L (es) |
| SG (1) | SG166768A1 (es) |
| TN (1) | TNSN06202A1 (es) |
| WO (1) | WO2005062955A2 (es) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LT2077282T (lt) | 2003-11-05 | 2017-03-10 | Roche Glycart Ag | Antigeną surišančios molekulės su padidintu fc receptoriaus surišimo giminingumu ir efektoriaus funkcija |
| AU2012216702B2 (en) * | 2005-08-26 | 2014-12-04 | Roche Glycart Ag | Modified antigen binding molecules with altered cell signaling activity |
| US20070071745A1 (en) * | 2005-08-26 | 2007-03-29 | Pablo Umana | Modified antigen binding molecules with altered cell signaling activity |
| US8949033B2 (en) | 2006-04-28 | 2015-02-03 | The Chemo-Sero-Therapeutic Research Institute | Method for quantification of neurotoxin |
| ES2694203T3 (es) | 2012-03-08 | 2018-12-19 | Ludwig Institute For Cancer Research Limited | Anticuerpos específicos del Tgf-1 y métodos y usos de los mismos |
| CA2866378A1 (en) | 2012-03-08 | 2013-09-12 | Selig Sealing Products, Inc. | Container sealing member with protected security component and removal tab |
| RU2670943C9 (ru) | 2012-11-08 | 2018-11-26 | Илэвэн Байотерапьютикс, Инк. | Антагонисты ил-6 и их применение |
| ES3051832T3 (en) | 2014-11-07 | 2025-12-30 | F Hoffmann La Roche Ltd | Improved il-6 antibodies |
| BR112017021484A2 (pt) | 2015-06-05 | 2018-07-03 | Novartis Ag | anticorpos de direcionamento à proteína morfogenética óssea 9 (bmp9) e métodos para os mesmos |
| CA2993645A1 (en) | 2015-07-28 | 2017-02-02 | Otonomy, Inc. | Trkb or trkc agonist compositions and methods for the treatment of otic conditions |
| KR20180116359A (ko) | 2016-02-23 | 2018-10-24 | 세센 바이오, 아이엔씨. | 인터루킨-6의 길항제 제제 및 이의 용도 |
| CN109689027A (zh) | 2016-06-29 | 2019-04-26 | 奥德纳米有限公司 | 甘油三酯耳用制剂及其用途 |
| KR20210046716A (ko) * | 2018-08-22 | 2021-04-28 | 메르크 파텐트 게엠베하 | 표적화된 TGF-β 억제에 의한 삼중 음성 유방암의 치료 |
| EP4146706A4 (en) | 2020-05-04 | 2024-05-29 | The Regents of the University of California | INHIBITION OF ANTI-ENPP1 ANTIBODIES |
| WO2023091887A1 (en) | 2021-11-16 | 2023-05-25 | Genentech, Inc. | Methods and compositions for treating systemic lupus erythematosus (sle) with mosunetuzumab |
| CN120118180B (zh) * | 2025-03-13 | 2025-12-05 | 中国兽医药品监察所 | 一种非洲猪瘟病毒p30蛋白单克隆抗体的制备及其应用 |
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| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| FR2413974A1 (fr) | 1978-01-06 | 1979-08-03 | David Bernard | Sechoir pour feuilles imprimees par serigraphie |
| US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| US4816567A (en) * | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| US5807715A (en) * | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| US4754065A (en) | 1984-12-18 | 1988-06-28 | Cetus Corporation | Precursor to nucleic acid probe |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4676980A (en) | 1985-09-23 | 1987-06-30 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Target specific cross-linked heteroantibodies |
| US4777127A (en) | 1985-09-30 | 1988-10-11 | Labsystems Oy | Human retrovirus-related products and methods of diagnosing and treating conditions associated with said retrovirus |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
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| US6548640B1 (en) * | 1986-03-27 | 2003-04-15 | Btg International Limited | Altered antibodies |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| IL85035A0 (en) * | 1987-01-08 | 1988-06-30 | Int Genetic Eng | Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same |
| GB8702816D0 (en) | 1987-02-07 | 1987-03-11 | Al Sumidaie A M K | Obtaining retrovirus-containing fraction |
| US5219740A (en) | 1987-02-13 | 1993-06-15 | Fred Hutchinson Cancer Research Center | Retroviral gene transfer into diploid fibroblasts for gene therapy |
| US5422120A (en) | 1988-05-30 | 1995-06-06 | Depotech Corporation | Heterovesicular liposomes |
| AP129A (en) | 1988-06-03 | 1991-04-17 | Smithkline Biologicals S A | Expression of retrovirus gag protein eukaryotic cells |
| GB8823869D0 (en) * | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5750373A (en) | 1990-12-03 | 1998-05-12 | Genentech, Inc. | Enrichment method for variant proteins having altered binding properties, M13 phagemids, and growth hormone variants |
| US5047335A (en) | 1988-12-21 | 1991-09-10 | The Regents Of The University Of Calif. | Process for controlling intracellular glycosylation of proteins |
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| WO1990007936A1 (en) | 1989-01-23 | 1990-07-26 | Chiron Corporation | Recombinant therapies for infection and hyperproliferative disorders |
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| US5604202A (en) | 1990-11-13 | 1997-02-18 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Use of NGF growth factors to treat drug-induced neuropathy |
| US5278299A (en) | 1991-03-18 | 1994-01-11 | Scripps Clinic And Research Foundation | Method and composition for synthesizing sialylated glycosyl compounds |
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| AU3144193A (en) * | 1991-11-21 | 1993-06-15 | Board Of Trustees Of The Leland Stanford Junior University | Controlling degradation of glycoprotein oligosaccharides by extracellular glycosisases |
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| FR2688514A1 (fr) | 1992-03-16 | 1993-09-17 | Centre Nat Rech Scient | Adenovirus recombinants defectifs exprimant des cytokines et medicaments antitumoraux les contenant. |
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| CN1099868C (zh) | 1993-11-16 | 2003-01-29 | 斯卡法玛公司 | 具有控制释放活性成分作用的囊 |
| US6436908B1 (en) | 1995-05-30 | 2002-08-20 | Duke University | Use of exogenous β-adrenergic receptor and β-adrenergic receptor kinase gene constructs to enhance myocardial function |
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| CA2212315A1 (en) * | 1997-08-05 | 1999-02-05 | Mcgill University | Pharmaceutical composition with neurotrophic-like biological activity |
| AU9692198A (en) | 1997-10-10 | 1999-05-03 | Kevin J. Donahue | Gene delivery compositions and methods |
| GB9809951D0 (en) | 1998-05-08 | 1998-07-08 | Univ Cambridge Tech | Binding molecules |
| WO2000053211A2 (en) | 1999-03-09 | 2000-09-14 | University Of Southern California | Method of promoting myocyte proliferation and myocardial tissue repair |
| ATE446366T1 (de) * | 2000-06-22 | 2009-11-15 | Genentech Inc | Agonistische monoklonale antikörper gegen trkc |
| WO2004058190A2 (en) * | 2002-12-23 | 2004-07-15 | Rinat Neuroscience Corp. | Methods for treating taxol-induced sensory neuropathy |
| SI1575517T1 (sl) | 2002-12-24 | 2012-06-29 | Rinat Neuroscience Corp | Protitelesa proti ĺ˝iväśnemu rastnemu dejavniku in metode njihove uporabe |
| EP1620127A4 (en) * | 2003-03-20 | 2007-04-04 | Rinat Neuroscience Corp | METHOD FOR TREATING TAXOL-INDUCED ANTI-FERROUS DISORDER |
-
2004
- 2004-12-23 KR KR1020067014886A patent/KR20070001932A/ko not_active Ceased
- 2004-12-23 US US10/584,443 patent/US7968690B2/en active Active
- 2004-12-23 EA EA200601220A patent/EA200601220A1/ru unknown
- 2004-12-23 WO PCT/US2004/043435 patent/WO2005062955A2/en not_active Ceased
- 2004-12-23 CA CA002551097A patent/CA2551097A1/en not_active Abandoned
- 2004-12-23 EP EP11183081A patent/EP2402756A3/en not_active Withdrawn
- 2004-12-23 EP EP04815503A patent/EP1700121A4/en not_active Withdrawn
- 2004-12-23 AP AP2006003670A patent/AP2006003670A0/xx unknown
- 2004-12-23 BR BRPI0417270-1A patent/BRPI0417270A/pt not_active Application Discontinuation
- 2004-12-23 AU AU2004308482A patent/AU2004308482A1/en not_active Abandoned
- 2004-12-23 SG SG201004521-9A patent/SG166768A1/en unknown
- 2004-12-23 JP JP2006547407A patent/JP4503617B2/ja not_active Expired - Fee Related
- 2004-12-23 CN CNA2004800414321A patent/CN1947012A/zh active Pending
-
2006
- 2006-06-21 IL IL176485A patent/IL176485A0/en unknown
- 2006-06-23 TN TNP2006000202A patent/TNSN06202A1/en unknown
- 2006-06-23 MA MA29131A patent/MA28395B1/fr unknown
- 2006-07-20 CR CR8525A patent/CR8525A/es not_active Application Discontinuation
- 2006-07-20 NO NO20063375A patent/NO20063375L/no not_active Application Discontinuation
- 2006-07-21 EC EC2006006722A patent/ECSP066722A/es unknown
-
2011
- 2011-05-13 US US13/107,861 patent/US20110281348A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP4503617B2 (ja) | 2010-07-14 |
| CN1947012A (zh) | 2007-04-11 |
| EP1700121A2 (en) | 2006-09-13 |
| US7968690B2 (en) | 2011-06-28 |
| MA28395B1 (fr) | 2007-01-02 |
| NO20063375L (no) | 2006-09-18 |
| WO2005062955A2 (en) | 2005-07-14 |
| AP2006003670A0 (en) | 2006-06-30 |
| EA200601220A1 (ru) | 2006-12-29 |
| CR8525A (es) | 2007-05-30 |
| IL176485A0 (en) | 2006-10-05 |
| EP2402756A2 (en) | 2012-01-04 |
| US20090202526A1 (en) | 2009-08-13 |
| AU2004308482A1 (en) | 2005-07-14 |
| CA2551097A1 (en) | 2005-07-14 |
| SG166768A1 (en) | 2010-12-29 |
| EP2402756A3 (en) | 2012-02-22 |
| TNSN06202A1 (en) | 2007-11-15 |
| KR20070001932A (ko) | 2007-01-04 |
| WO2005062955A3 (en) | 2006-06-22 |
| US20110281348A1 (en) | 2011-11-17 |
| EP1700121A4 (en) | 2008-09-03 |
| JP2007519401A (ja) | 2007-07-19 |
| BRPI0417270A (pt) | 2007-03-27 |
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