ECSP088102A - Compuestos para el tratamiento de infecciones bacterianas resistentes a múltiples fármacos - Google Patents
Compuestos para el tratamiento de infecciones bacterianas resistentes a múltiples fármacosInfo
- Publication number
- ECSP088102A ECSP088102A EC2008008102A ECSP088102A ECSP088102A EC SP088102 A ECSP088102 A EC SP088102A EC 2008008102 A EC2008008102 A EC 2008008102A EC SP088102 A ECSP088102 A EC SP088102A EC SP088102 A ECSP088102 A EC SP088102A
- Authority
- EC
- Ecuador
- Prior art keywords
- treatment
- compounds
- bacterial infections
- medicaments
- multiple drugs
- Prior art date
Links
- 208000035143 Bacterial infection Diseases 0.000 title abstract 4
- 208000022362 bacterial infectious disease Diseases 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 239000003814 drug Substances 0.000 title abstract 4
- 229940079593 drug Drugs 0.000 title 1
- 241001465754 Metazoa Species 0.000 abstract 3
- 241000282412 Homo Species 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 241000282414 Homo sapiens Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
La presente invención se refiere a compuestos que presentan actividad antibacteriana, a procesos para su preparación, a composiciones farmacéuticas que los contienen como ingrediente activo, a su uso como medicamentos y a su uso en la fabricación de medicamentos para uso en el tratamiento de infecciones bacterianas en animales de sangre caliente, tales como seres humanos. En particular, esta invención se refiere a compuestos útiles para el tratamiento de infecciones bacterianas en animales de sangre caliente, tales como seres humanos, más particularmente, al uso de estos compuestos en la fabricación de medicamentos para uso en el tratamiento de infecciones bacterianas en animales de sangre caliente, tales como seres humanos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69134005P | 2005-06-16 | 2005-06-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP088102A true ECSP088102A (es) | 2008-02-20 |
Family
ID=36956054
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2008008102A ECSP088102A (es) | 2005-06-16 | 2008-01-11 | Compuestos para el tratamiento de infecciones bacterianas resistentes a múltiples fármacos |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US7875715B2 (es) |
| EP (2) | EP1893599A1 (es) |
| JP (1) | JP5204649B2 (es) |
| KR (2) | KR20080021031A (es) |
| CN (1) | CN101243068B (es) |
| AR (1) | AR054781A1 (es) |
| AU (1) | AU2006258879C1 (es) |
| BR (1) | BRPI0611747A2 (es) |
| CA (1) | CA2610900A1 (es) |
| EC (1) | ECSP088102A (es) |
| IL (1) | IL187581A0 (es) |
| MX (1) | MX2007015297A (es) |
| MY (1) | MY150958A (es) |
| NO (1) | NO20080338L (es) |
| NZ (1) | NZ565110A (es) |
| RU (1) | RU2008100306A (es) |
| TW (1) | TW200716623A (es) |
| UY (1) | UY29608A1 (es) |
| WO (1) | WO2006134378A1 (es) |
| ZA (1) | ZA200710563B (es) |
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| HRP20100194T8 (hr) * | 2005-10-21 | 2010-06-30 | Glaxo Group Limited | Perikondenzirani triciklički spojevi, korisni kao antibakterijska sredstva |
| ATE481406T1 (de) | 2006-04-06 | 2010-10-15 | Glaxo Group Ltd | Pyrrolochinoxalinonderivate als antibakterielle mittel |
| MX2008014908A (es) * | 2006-05-26 | 2009-05-13 | Toyama Chemical Co Ltd | Compuesto heterociclico nuevo o sal del mismo e intermedio del mismo. |
| TW200815425A (en) * | 2006-06-08 | 2008-04-01 | Speedel Experimenta Ag | 2,5-disubstituted piperidines |
| EP1992628A1 (en) | 2007-05-18 | 2008-11-19 | Glaxo Group Limited | Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones |
| CA2657258A1 (en) | 2006-07-20 | 2008-01-24 | Novartis Ag | Amino-piperidine derivatives as cetp inhibitors |
| JP5315239B2 (ja) * | 2006-07-20 | 2013-10-16 | グラクソ グループ リミテッド | N−エチルキノロンおよびn−エチルアザキノロンの誘導体およびアナログ |
| US20100144717A1 (en) * | 2006-12-15 | 2010-06-10 | Janelle Comita-Prevoir | 2-quinolinone and 2-quinoxalinone-derivatives and their use as antibacterial agents |
| WO2008071981A1 (en) * | 2006-12-15 | 2008-06-19 | Astrazeneca Ab | Piperidines for the treatment of bacterial infections |
| WO2008071964A1 (en) * | 2006-12-15 | 2008-06-19 | Astrazeneca Ab | Naphthyridine bactericides |
| TW200831517A (en) * | 2006-12-15 | 2008-08-01 | Astrazeneca Ab | Chemical compounds |
| WO2008071962A1 (en) * | 2006-12-15 | 2008-06-19 | Astrazeneca Ab | Pteridines and pyrimidinopyridines as antibacterial agents |
| GB0707704D0 (en) * | 2007-04-20 | 2007-05-30 | Glaxo Group Ltd | Compounds |
| PT2137196E (pt) * | 2007-04-20 | 2010-12-16 | Glaxo Group Ltd | Compostos tricíclicos contendo azoto como agentes antibacterianos |
| US7662967B2 (en) | 2007-08-02 | 2010-02-16 | Cambridge Enterprise Limited | Anti-inflammatory compounds and compositions |
| GB2452696B (en) | 2007-08-02 | 2009-09-23 | Cambridge Entpr Ltd | 3-(2',2'-dimethylpropanoylamino)-tetrahydropyridin-2-one and its use in pharmaceutical compositions |
| PL2207775T3 (pl) | 2007-11-05 | 2012-08-31 | Novartis Ag | Pochodne 4-benzyloamino-1-karboksyacylo-piperydyny jako inhibitory CETP użyteczne do leczenia chorób, takich jak hiperlipidemia lub stwardnienie tętnic |
| US8354426B2 (en) * | 2007-11-26 | 2013-01-15 | Toyama Chemical Co., Ltd. | Naphthyridine derivative monohydrate and method for producing the same |
| JP5620636B2 (ja) * | 2007-11-26 | 2014-11-05 | 富山化学工業株式会社 | 新規な複素環化合物またはその塩を含有する抗菌剤 |
| AU2008333272B2 (en) | 2007-12-03 | 2012-03-29 | Novartis Ag | 1,2-disubstituted-4-benzylamino-pyrrolidine derivatives as CETP inhibitors useful for the treatment of diseases such as hyperli pidemia or arteriosclerosis |
| CA2713187C (en) * | 2008-02-22 | 2016-06-07 | Actelion Pharmaceuticals Ltd | Oxazolidinone derivatives |
| US7960377B2 (en) | 2008-03-28 | 2011-06-14 | Cara Therapeutics, Inc. | Substituted pyridoxazines |
| WO2009128019A1 (en) | 2008-04-15 | 2009-10-22 | Actelion Pharmaceuticals Ltd | Tricyclic antibiotics |
| AU2009254738B2 (en) * | 2008-06-03 | 2014-05-08 | Idorsia Pharmaceuticals Ltd | [4-(1-amino-ethyl) -cyclohexyl] -methyl-amine and [6-(1-amino-ethyl) -tetrahydro- pyran-3-yl] -methyl-amine derivatives as antibacterials |
| JP5490809B2 (ja) | 2008-10-10 | 2014-05-14 | アクテリオン ファーマシューティカルズ リミテッド | オキサゾリジニル抗生物質 |
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| TW201309689A (zh) | 2011-02-07 | 2013-03-01 | Daiichi Sankyo Co Ltd | 含胺基之吡咯啶酮衍生物 |
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| EP2888229B1 (en) * | 2012-08-01 | 2019-02-06 | Merck Sharp & Dohme Corp. | alpha7 NICOTINIC ACETYLCHOLINE RECEPTOR MODULATORS AND USES THEREOF |
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| CR20220170A (es) | 2019-10-11 | 2022-10-10 | Incyte Corp | Aminas bicíclicas como inhibidoras de la cdk2 |
| US11981671B2 (en) | 2021-06-21 | 2024-05-14 | Incyte Corporation | Bicyclic pyrazolyl amines as CDK2 inhibitors |
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| TW200507841A (en) | 2003-03-27 | 2005-03-01 | Glaxo Group Ltd | Antibacterial agents |
| US7232833B2 (en) | 2003-03-28 | 2007-06-19 | Novexel | 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them |
| FR2852954B1 (fr) * | 2003-03-28 | 2006-07-14 | Aventis Pharma Sa | Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent |
| DE10316081A1 (de) | 2003-04-08 | 2004-10-21 | Morphochem AG Aktiengesellschaft für kombinatorische Chemie | Neue Verbindungen mit antibakterieller Aktivität |
| CN101348824A (zh) * | 2003-06-12 | 2009-01-21 | 卫材R&D管理有限公司 | 神经细胞保护剂 |
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| CA2551686C (en) | 2004-01-07 | 2014-09-23 | Ian Irwin | Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
| EP1796466A4 (en) | 2004-06-15 | 2009-09-02 | Glaxo Group Ltd | ANTIBACTERIAL AGENTS |
| FR2872164B1 (fr) | 2004-06-29 | 2006-11-17 | Aventis Pharma Sa | Derives de quinoleines-4-substituees, leur procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent |
| JP5100376B2 (ja) * | 2004-06-30 | 2012-12-19 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Parp阻害剤としてのキナゾリンジオン誘導体 |
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| EP1784410A4 (en) | 2004-08-09 | 2009-07-15 | Glaxo Group Ltd | ANTIBACTERIAL AGENTS |
| DE102004041163A1 (de) | 2004-08-25 | 2006-03-02 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Neue Verbindungen mit antibakterieller Aktivität |
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| JP5314244B2 (ja) | 2004-10-27 | 2013-10-16 | 富山化学工業株式会社 | 新規な含窒素複素環化合物およびその塩 |
| ES2430569T3 (es) | 2005-02-18 | 2013-11-21 | Astrazeneca Ab | Compuestos antibacterianos derivados de piperidina |
| WO2006099884A1 (en) | 2005-03-24 | 2006-09-28 | Actelion Percurex Ag | Beta-aminoalcohol antibiotics |
| KR20080016577A (ko) | 2005-05-24 | 2008-02-21 | 아스트라제네카 아베 | 항균 활성을 갖는 아미노피페리딘 퀴놀린 및 이들의아자이소스테릭 유사체 |
| MY150958A (en) | 2005-06-16 | 2014-03-31 | Astrazeneca Ab | Compounds for the treatment of multi-drug resistant bacterial infections |
| EP2468743A1 (en) * | 2005-06-24 | 2012-06-27 | Toyama Chemical Co., Ltd. | Nitrogen-containing bicyclic compounds useful as antibacterial agents |
| WO2007042325A1 (de) | 2005-10-13 | 2007-04-19 | Morphochem Aktiengesellschaft für kombinatorische Chemie | 5-chinolinderivate mit antibakterieller aktivität |
| US7709496B2 (en) | 2006-04-06 | 2010-05-04 | Glaxo Group Limited | Antibacterial agents |
| MX2008014908A (es) | 2006-05-26 | 2009-05-13 | Toyama Chemical Co Ltd | Compuesto heterociclico nuevo o sal del mismo e intermedio del mismo. |
| US20100144717A1 (en) | 2006-12-15 | 2010-06-10 | Janelle Comita-Prevoir | 2-quinolinone and 2-quinoxalinone-derivatives and their use as antibacterial agents |
| TW200831517A (en) | 2006-12-15 | 2008-08-01 | Astrazeneca Ab | Chemical compounds |
-
2006
- 2006-06-14 MY MYPI20062824 patent/MY150958A/en unknown
- 2006-06-16 MX MX2007015297A patent/MX2007015297A/es active IP Right Grant
- 2006-06-16 JP JP2008516408A patent/JP5204649B2/ja not_active Expired - Fee Related
- 2006-06-16 WO PCT/GB2006/002207 patent/WO2006134378A1/en not_active Ceased
- 2006-06-16 US US11/917,394 patent/US7875715B2/en not_active Expired - Fee Related
- 2006-06-16 EP EP06744233A patent/EP1893599A1/en not_active Withdrawn
- 2006-06-16 UY UY29608A patent/UY29608A1/es unknown
- 2006-06-16 EP EP10178524A patent/EP2289890A1/en not_active Withdrawn
- 2006-06-16 NZ NZ565110A patent/NZ565110A/en not_active IP Right Cessation
- 2006-06-16 AR ARP060102576A patent/AR054781A1/es not_active Application Discontinuation
- 2006-06-16 KR KR1020077029378A patent/KR20080021031A/ko not_active Ceased
- 2006-06-16 TW TW095121757A patent/TW200716623A/zh unknown
- 2006-06-16 AU AU2006258879A patent/AU2006258879C1/en not_active Ceased
- 2006-06-16 RU RU2008100306/04A patent/RU2008100306A/ru not_active Application Discontinuation
- 2006-06-16 KR KR1020137021678A patent/KR101351160B1/ko not_active Expired - Fee Related
- 2006-06-16 BR BRPI0611747-3A patent/BRPI0611747A2/pt not_active IP Right Cessation
- 2006-06-16 CN CN2006800293947A patent/CN101243068B/zh not_active Expired - Fee Related
- 2006-06-16 CA CA002610900A patent/CA2610900A1/en not_active Abandoned
-
2007
- 2007-11-22 IL IL187581A patent/IL187581A0/en unknown
- 2007-12-04 ZA ZA200710563A patent/ZA200710563B/xx unknown
-
2008
- 2008-01-11 EC EC2008008102A patent/ECSP088102A/es unknown
- 2008-01-16 NO NO20080338A patent/NO20080338L/no not_active Application Discontinuation
-
2010
- 2010-12-09 US US12/964,366 patent/US8124602B2/en not_active Expired - Fee Related
-
2012
- 2012-01-11 US US13/348,143 patent/US20120108577A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| RU2008100306A (ru) | 2009-07-27 |
| KR20080021031A (ko) | 2008-03-06 |
| UY29608A1 (es) | 2007-01-31 |
| KR20130108468A (ko) | 2013-10-02 |
| US7875715B2 (en) | 2011-01-25 |
| AR054781A1 (es) | 2007-07-18 |
| NZ565110A (en) | 2011-05-27 |
| US20120108577A1 (en) | 2012-05-03 |
| CN101243068B (zh) | 2012-08-08 |
| WO2006134378A1 (en) | 2006-12-21 |
| AU2006258879B2 (en) | 2009-11-19 |
| CN101243068A (zh) | 2008-08-13 |
| CA2610900A1 (en) | 2006-12-21 |
| KR101351160B1 (ko) | 2014-01-14 |
| MY150958A (en) | 2014-03-31 |
| TW200716623A (en) | 2007-05-01 |
| AU2006258879C1 (en) | 2011-09-01 |
| NO20080338L (no) | 2008-02-29 |
| US20100152441A1 (en) | 2010-06-17 |
| MX2007015297A (es) | 2008-02-21 |
| EP2289890A1 (en) | 2011-03-02 |
| IL187581A0 (en) | 2008-03-20 |
| JP5204649B2 (ja) | 2013-06-05 |
| US8124602B2 (en) | 2012-02-28 |
| ZA200710563B (en) | 2008-12-31 |
| JP2008543819A (ja) | 2008-12-04 |
| US20110092495A1 (en) | 2011-04-21 |
| BRPI0611747A2 (pt) | 2008-12-02 |
| EP1893599A1 (en) | 2008-03-05 |
| AU2006258879A1 (en) | 2006-12-21 |
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