ECSP088254A - Compuestos activos en ppar - Google Patents

Compuestos activos en ppar

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Publication number
ECSP088254A
ECSP088254A EC2008008254A ECSP088254A ECSP088254A EC SP088254 A ECSP088254 A EC SP088254A EC 2008008254 A EC2008008254 A EC 2008008254A EC SP088254 A ECSP088254 A EC SP088254A EC SP088254 A ECSP088254 A EC SP088254A
Authority
EC
Ecuador
Prior art keywords
ppar
active compounds
ppard
pparg
ppara
Prior art date
Application number
EC2008008254A
Other languages
English (en)
Inventor
Prabha N Ibrahim
Jack Lin
Weiru Wang
Chao Zhang
Shenghua Shi
Dean R Artis
Patrick Womack
Byunghun Lee
Rebecca Zuckerman
Original Assignee
Plexxikon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Plexxikon Inc filed Critical Plexxikon Inc
Publication of ECSP088254A publication Critical patent/ECSP088254A/es

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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/46—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
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    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
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    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
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    • C07C59/76—Unsaturated compounds containing keto groups
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    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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Abstract

Se describen compuestos que son activos en al menos uno de PPARa, PPARd, y PPARg, que son útiles para los métodos terapéuticos y/o profilácticos que involucran la modulación de al menos uno de PPARa, PPARd, y PPARg.
EC2008008254A 2005-09-07 2008-03-07 Compuestos activos en ppar ECSP088254A (es)

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US71521405P 2005-09-07 2005-09-07
US78938706P 2006-04-05 2006-04-05

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ECSP088254A true ECSP088254A (es) 2008-04-28

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US (1) US20080249137A1 (es)
EP (1) EP1940767A2 (es)
JP (1) JP2009507846A (es)
KR (1) KR20080042170A (es)
AR (1) AR057800A1 (es)
AU (1) AU2006287521A1 (es)
BR (1) BRPI0615948A2 (es)
CA (1) CA2621406A1 (es)
CR (1) CR9869A (es)
EC (1) ECSP088254A (es)
GT (1) GT200600407A (es)
IL (1) IL189775A0 (es)
NO (1) NO20081042L (es)
PE (1) PE20071185A1 (es)
RU (1) RU2008108221A (es)
TW (1) TW200800872A (es)
WO (1) WO2007030567A2 (es)

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US20080249137A1 (en) 2008-10-09
EP1940767A2 (en) 2008-07-09
NO20081042L (no) 2008-05-22
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JP2009507846A (ja) 2009-02-26
PE20071185A1 (es) 2007-12-01
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GT200600407A (es) 2007-04-10
AU2006287521A1 (en) 2007-03-15
AR057800A1 (es) 2007-12-19
IL189775A0 (en) 2008-08-07
KR20080042170A (ko) 2008-05-14
CR9869A (es) 2008-05-16
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