ECSP088281A - Moduladores del metabolismo y tratamiento de los trastornos metabólicos - Google Patents

Moduladores del metabolismo y tratamiento de los trastornos metabólicos

Info

Publication number
ECSP088281A
ECSP088281A EC2008008281A ECSP088281A ECSP088281A EC SP088281 A ECSP088281 A EC SP088281A EC 2008008281 A EC2008008281 A EC 2008008281A EC SP088281 A ECSP088281 A EC SP088281A EC SP088281 A ECSP088281 A EC SP088281A
Authority
EC
Ecuador
Prior art keywords
treatment
metabolic disorders
metabolism modulators
yloxy
modulators
Prior art date
Application number
EC2008008281A
Other languages
English (en)
Inventor
Robert M Jones
Juerg Lehmann
Original Assignee
Arena Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37845245&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP088281(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
Publication of ECSP088281A publication Critical patent/ECSP088281A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se refiere al éster isopropílico del ácido 4-[5-metil-6-(2-metil-piridin-3-iloxi)-pirimidin-4-iloxi]-piperidin-l-carboxílico, sus sales, solvatos e hidratos farmacéuticamente aceptables que son moduladores del metabolismo de la glucosa. En consecuencia, los compuestos de la presente invención son útiles en el tratamiento de los trastornos metabólicos y sus complicaciones, como la diabetes y la obesidad.
EC2008008281A 2005-09-16 2008-03-14 Moduladores del metabolismo y tratamiento de los trastornos metabólicos ECSP088281A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US71801505P 2005-09-16 2005-09-16

Publications (1)

Publication Number Publication Date
ECSP088281A true ECSP088281A (es) 2008-04-28

Family

ID=37845245

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2008008281A ECSP088281A (es) 2005-09-16 2008-03-14 Moduladores del metabolismo y tratamiento de los trastornos metabólicos

Country Status (25)

Country Link
US (1) US20100160359A1 (es)
EP (1) EP1931654B1 (es)
JP (1) JP2009508861A (es)
KR (1) KR20080044296A (es)
CN (1) CN101263135A (es)
AT (1) ATE429430T1 (es)
AU (1) AU2006292620A1 (es)
BR (1) BRPI0616245A2 (es)
CA (1) CA2619093A1 (es)
DE (1) DE602006006461D1 (es)
DK (1) DK1931654T3 (es)
EA (1) EA013084B1 (es)
EC (1) ECSP088281A (es)
ES (1) ES2326391T3 (es)
GE (1) GEP20104966B (es)
IL (1) IL189490A0 (es)
MA (1) MA29860B1 (es)
MX (1) MX2008003634A (es)
NI (1) NI200800078A (es)
NO (1) NO20081810L (es)
NZ (1) NZ565898A (es)
RS (1) RS20080112A (es)
TN (1) TNSN08097A1 (es)
WO (1) WO2007035355A2 (es)
ZA (1) ZA200801704B (es)

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MA29860B1 (fr) 2008-10-03
EA013084B1 (ru) 2010-02-26
JP2009508861A (ja) 2009-03-05
NZ565898A (en) 2010-07-30
IL189490A0 (en) 2008-08-07
ZA200801704B (en) 2008-11-26
NI200800078A (es) 2009-03-03
WO2007035355A2 (en) 2007-03-29
ATE429430T1 (de) 2009-05-15
US20100160359A1 (en) 2010-06-24
AU2006292620A1 (en) 2007-03-29
EP1931654B1 (en) 2009-04-22
DE602006006461D1 (de) 2009-06-04
CA2619093A1 (en) 2007-03-29
DK1931654T3 (da) 2009-07-27
EP1931654A2 (en) 2008-06-18
BRPI0616245A2 (pt) 2011-06-14
TNSN08097A1 (en) 2009-07-14
MX2008003634A (es) 2009-10-08
WO2007035355A3 (en) 2007-06-21
NO20081810L (no) 2008-04-14
KR20080044296A (ko) 2008-05-20
RS20080112A (sr) 2009-05-06
EA200800834A1 (ru) 2008-08-29
CN101263135A (zh) 2008-09-10
GEP20104966B (en) 2010-04-26
HK1112908A1 (en) 2008-09-19

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