ECSP088796A - Metodos para la prevencion y tratamiento de condiciones que surgen de deficiencia de estrogeno local - Google Patents
Metodos para la prevencion y tratamiento de condiciones que surgen de deficiencia de estrogeno localInfo
- Publication number
- ECSP088796A ECSP088796A EC2008008796A ECSP088796A ECSP088796A EC SP088796 A ECSP088796 A EC SP088796A EC 2008008796 A EC2008008796 A EC 2008008796A EC SP088796 A ECSP088796 A EC SP088796A EC SP088796 A ECSP088796 A EC SP088796A
- Authority
- EC
- Ecuador
- Prior art keywords
- vulvar
- vaginal
- local
- methods
- conjugated estrogens
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 230000002265 prevention Effects 0.000 title abstract 2
- 230000007812 deficiency Effects 0.000 title 1
- 229940035811 conjugated estrogen Drugs 0.000 abstract 4
- 206010003694 Atrophy Diseases 0.000 abstract 2
- 230000037444 atrophy Effects 0.000 abstract 2
- 239000000262 estrogen Substances 0.000 abstract 2
- 229940011871 estrogen Drugs 0.000 abstract 2
- 208000004746 Atrophic Vaginitis Diseases 0.000 abstract 1
- 206010003693 Atrophic vulvovaginitis Diseases 0.000 abstract 1
- 208000004483 Dyspareunia Diseases 0.000 abstract 1
- 206010030247 Oestrogen deficiency Diseases 0.000 abstract 1
- 208000003251 Pruritus Diseases 0.000 abstract 1
- 201000001880 Sexual dysfunction Diseases 0.000 abstract 1
- 206010047791 Vulvovaginal dryness Diseases 0.000 abstract 1
- 206010056530 Vulvovaginal pruritus Diseases 0.000 abstract 1
- -1 conjugated estrogens Substances 0.000 abstract 1
- 239000006071 cream Substances 0.000 abstract 1
- 230000007803 itching Effects 0.000 abstract 1
- 201000010808 postmenopausal atrophic vaginitis Diseases 0.000 abstract 1
- 239000000583 progesterone congener Substances 0.000 abstract 1
- 231100000872 sexual dysfunction Toxicity 0.000 abstract 1
- 238000007910 systemic administration Methods 0.000 abstract 1
- 201000006669 vulvar dystrophy Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
La presente invención se refiere a métodos para la prevención y tratamiento de condiciones que surgen de deficiencia de estrógeno local, tales como dispareunia, atrofia vulvar, atrofia vaginal, resequedad vaginal, comezón vulvar, comezón vaginal, ardor vulvar, ardor vaginal, distrofia vulvar, vaginitis atrófica o disfunción sexual menopáusica; en algunas modalidades, los métodos incluyen administración sistémica, por ejemplo oral, de un estrógeno, tal como estrógenos conjugados, y un progestágeno, tal como MPA, contemporáneamente con administración local de un estrógeno, por ejemplo, estrógenos conjugados; en algunas modalidades, los métodos incluyen la administración oral de estrógenos conjugados y MPA, y la administración vulvar, vaginal, o vulvar y vaginal, de estrógenos conjugados, por ejemplo, en una crema
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78951706P | 2006-04-05 | 2006-04-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP088796A true ECSP088796A (es) | 2008-11-27 |
Family
ID=38523460
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2008008796A ECSP088796A (es) | 2006-04-05 | 2008-10-06 | Metodos para la prevencion y tratamiento de condiciones que surgen de deficiencia de estrogeno local |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20070238713A1 (es) |
| EP (1) | EP2004200A2 (es) |
| JP (1) | JP2009532505A (es) |
| KR (1) | KR20080108120A (es) |
| CN (1) | CN101415427A (es) |
| AU (1) | AU2007234841A1 (es) |
| BR (1) | BRPI0709924A2 (es) |
| CA (1) | CA2644913A1 (es) |
| CR (1) | CR10259A (es) |
| EC (1) | ECSP088796A (es) |
| GT (1) | GT200800205A (es) |
| IL (1) | IL193810A0 (es) |
| MX (1) | MX2008012880A (es) |
| NO (1) | NO20083789L (es) |
| RU (1) | RU2008136024A (es) |
| WO (1) | WO2007118135A2 (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2381947A4 (en) | 2008-12-23 | 2012-08-22 | Quest Diagnostics Invest Inc | MASS SPECTROMETRY ASSAY FOR STROGENIC COMPOUNDS |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| RS62297B1 (sr) | 2011-11-23 | 2021-09-30 | Therapeuticsmd Inc | Prirodne kombinovane hormonske supstitucione formulacije i terapije |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| US9931349B2 (en) | 2016-04-01 | 2018-04-03 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010034340A1 (en) * | 2000-03-20 | 2001-10-25 | American Home Products Corporation | Hormone replacement therapy |
| AU2002338277B2 (en) * | 2001-03-16 | 2007-11-22 | Wyeth | Estrogen replacement therapy |
| CA2446849A1 (en) * | 2001-05-16 | 2002-11-21 | Endeavor Pharmaceuticals | Treatment of conditions relating to hormone deficiencies by administration of progestins |
-
2007
- 2007-04-05 CA CA002644913A patent/CA2644913A1/en not_active Abandoned
- 2007-04-05 CN CNA2007800124125A patent/CN101415427A/zh not_active Withdrawn
- 2007-04-05 MX MX2008012880A patent/MX2008012880A/es unknown
- 2007-04-05 AU AU2007234841A patent/AU2007234841A1/en not_active Abandoned
- 2007-04-05 JP JP2009504473A patent/JP2009532505A/ja active Pending
- 2007-04-05 BR BRPI0709924-0A patent/BRPI0709924A2/pt not_active Application Discontinuation
- 2007-04-05 WO PCT/US2007/066042 patent/WO2007118135A2/en not_active Ceased
- 2007-04-05 RU RU2008136024/14A patent/RU2008136024A/ru not_active Application Discontinuation
- 2007-04-05 US US11/696,917 patent/US20070238713A1/en not_active Abandoned
- 2007-04-05 KR KR1020087024302A patent/KR20080108120A/ko not_active Withdrawn
- 2007-04-05 EP EP07760168A patent/EP2004200A2/en not_active Withdrawn
-
2008
- 2008-08-28 CR CR10259A patent/CR10259A/es not_active Application Discontinuation
- 2008-09-01 IL IL193810A patent/IL193810A0/en unknown
- 2008-09-03 NO NO20083789A patent/NO20083789L/no not_active Application Discontinuation
- 2008-10-02 GT GT200800205A patent/GT200800205A/es unknown
- 2008-10-06 EC EC2008008796A patent/ECSP088796A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO20083789L (no) | 2008-09-30 |
| MX2008012880A (es) | 2008-10-13 |
| GT200800205A (es) | 2009-05-15 |
| RU2008136024A (ru) | 2010-05-10 |
| CR10259A (es) | 2008-11-26 |
| AU2007234841A1 (en) | 2007-10-18 |
| EP2004200A2 (en) | 2008-12-24 |
| US20070238713A1 (en) | 2007-10-11 |
| CA2644913A1 (en) | 2007-10-18 |
| BRPI0709924A2 (pt) | 2011-07-26 |
| JP2009532505A (ja) | 2009-09-10 |
| IL193810A0 (en) | 2009-08-03 |
| CN101415427A (zh) | 2009-04-22 |
| KR20080108120A (ko) | 2008-12-11 |
| WO2007118135A2 (en) | 2007-10-18 |
| WO2007118135A3 (en) | 2008-04-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CR10259A (es) | Metodos para la prevencion y tratamiento de condiciones que surgen de deficiencia de estrogeno local | |
| HN2008000621A (es) | Metodo para la anticopcepcion hormonal preventiva bajo demanda | |
| MX2010005346A (es) | Composiciones farmaceuticas. | |
| GEP20156281B (en) | Orally administered corticosteroid compositions | |
| AR064077A1 (es) | Composiciones bajo forma de unguento sin vaselina que comprende un derivado de vitamina d y eventualmente un anti-inflamatorio esteroide | |
| NI201700100A (es) | Composiciones farmacéuticas para terapia combinada | |
| UY30109A1 (es) | Formas farmacológicas en forma de película para usar en la cavidad bucal (obleas) | |
| PE20120860A1 (es) | Combinacion farmaceutica que comprende levonorgestrel en combinacion con piroxicam, indometacina o diclofenaco | |
| PE20070329A1 (es) | Composiciones con estrogenos y metodos terapeuticos para su uso | |
| IN2012DN02661A (es) | ||
| ECSP034654A (es) | Productos de hormona esteroide y metodos para preparar los mismos | |
| MX2010004353A (es) | Combinación anticonceptiva oral entiemética. | |
| NI201000183A (es) | Regímenes de dosificación de antiprogestina. | |
| CL2012002722A1 (es) | Forma farmaceutica parenteral que libera un inhibidor de aromatasa tal como anastrozol y exemestano, y un gestageno tal como levonorgestrel y gestodeno; y su uso para el tratamiento simultaneo de endometriosis y para la anticoncepcion. | |
| CL2011003172A1 (es) | Composicion farmaceutica que comprende a) un excepiente, b) al menos un precursor de esteroides sexuales, c) al menos un modulador selectivo del receptor de estrogenos o una antiestrogeno y no contiene una progestina y/o un estrogeno; kit farmaceutico; y uso para reducir o eliminar sofocos, sintomas vasomotores y sudores nocturnos. | |
| BR112014012444A2 (pt) | formulações e terapias de reposição hormonal natural combinada | |
| AR066824A1 (es) | Metodo y disposicion para preparar lodo de yeso que contiene un eter de celulosa | |
| CL2011000214A1 (es) | Composicion farmaceutica que comprende progesterona micronizada y aceite de cartamo tipo ii; y uso para el tratamiento de una condicion relacionada con la insuficiencia de secrecion de progesterona. | |
| PE20060275A1 (es) | Composicion farmaceutica que contiene progestina y estrogeno para el tratamiento de trastorno disforico premenstrual | |
| ECSP077131A (es) | Regímenes y los juegos de anticonceptivos del antagonista del receptor de progesterona | |
| PE20070188A1 (es) | Formulaciones de estrogenos conjugados y bazedoxifeno | |
| ECSP099482A (es) | Preparación farmacéutica para reducir la endometriosis | |
| TW200612962A (en) | Estriol and estetrol prodrugs | |
| PA8803001A1 (es) | Uso de un gestágeno en combinacion con un estrogeno y uno o varios excipientes/portadores farmaceuticamente aceptables para la anticoncepcion oral sin lactosa | |
| CU20100084A7 (es) | Uso de un gestágeno en combinación con un estrógeno y uno o varios excipientes/portadores farmacéuticamente aceptables para la anticoncepción oral sin lactosa |