ECSP088835A - Terapia combinatoria que involucra antagonistas de alfa5beta1 - Google Patents

Terapia combinatoria que involucra antagonistas de alfa5beta1

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Publication number
ECSP088835A
ECSP088835A EC2008008835A ECSP088835A ECSP088835A EC SP088835 A ECSP088835 A EC SP088835A EC 2008008835 A EC2008008835 A EC 2008008835A EC SP088835 A ECSP088835 A EC SP088835A EC SP088835 A ECSP088835 A EC SP088835A
Authority
EC
Ecuador
Prior art keywords
antagonists
alfa5beta1
therapy involving
relates
present
Prior art date
Application number
EC2008008835A
Other languages
English (en)
Inventor
Yan Wu
Weilan Ye
Anan Chuntharapai
Greg Plowman
Marc Tessier-Lavigne
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of ECSP088835A publication Critical patent/ECSP088835A/es

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    • C07K16/2842—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
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Abstract

La presente invención se refiere al uso de antagonistas del VEGF y antagonistas de la alfa5beta1 para el tratamiento del cáncer y la inhibición de la angiogénesis y/o la permeabilidad vascular, incluida la inhibición de la angiogénesis anormal en las enfermedades. La presente invención también se refiere al uso de agonistas del VEGFR y agonistas de la alfa5beta1 para promover la angiogénesis y la permeabilidad vascular. La presente invención se refiere también a nuevos anticuerpos anti-alfa5beta1, composiciones y kits que los comprenden y a los métodos de obtenerlos y usarlos.
EC2008008835A 2006-03-21 2008-10-21 Terapia combinatoria que involucra antagonistas de alfa5beta1 ECSP088835A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78470406P 2006-03-21 2006-03-21
US78533006P 2006-03-22 2006-03-22
US87174306P 2006-12-22 2006-12-22

Publications (1)

Publication Number Publication Date
ECSP088835A true ECSP088835A (es) 2008-11-27

Family

ID=39402298

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2008008835A ECSP088835A (es) 2006-03-21 2008-10-21 Terapia combinatoria que involucra antagonistas de alfa5beta1

Country Status (27)

Country Link
US (3) US20090220504A1 (es)
EP (2) EP1989231B1 (es)
JP (2) JP5298007B2 (es)
KR (1) KR101454491B1 (es)
AR (1) AR060040A1 (es)
AU (1) AU2007319757B2 (es)
BR (1) BRPI0709338A2 (es)
CA (1) CA2646611A1 (es)
CR (1) CR10311A (es)
DK (1) DK1989231T3 (es)
EC (1) ECSP088835A (es)
ES (1) ES2544957T3 (es)
HR (1) HRP20150884T1 (es)
HU (1) HUE025989T2 (es)
IL (1) IL193926A (es)
MA (1) MA30384B1 (es)
MX (1) MX2008011905A (es)
MY (1) MY159375A (es)
NO (1) NO20084396L (es)
NZ (3) NZ615012A (es)
PL (1) PL1989231T3 (es)
PT (1) PT1989231E (es)
RS (1) RS54156B1 (es)
RU (1) RU2012129350A (es)
TW (1) TWI397535B (es)
UA (1) UA100969C2 (es)
WO (1) WO2008060645A2 (es)

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