ECSP088951A - /composición farmacéutica estable que contiene docetaxel y método para su fabricación - Google Patents

/composición farmacéutica estable que contiene docetaxel y método para su fabricación

Info

Publication number
ECSP088951A
ECSP088951A EC2008008951A ECSP088951A ECSP088951A EC SP088951 A ECSP088951 A EC SP088951A EC 2008008951 A EC2008008951 A EC 2008008951A EC SP088951 A ECSP088951 A EC SP088951A EC SP088951 A ECSP088951 A EC SP088951A
Authority
EC
Ecuador
Prior art keywords
pharmaceutical composition
containing docetaxel
stable pharmaceutical
manufacturing
composition containing
Prior art date
Application number
EC2008008951A
Other languages
English (en)
Inventor
Nam Ho Kim
Jin Young Lee
Jae-Sun Kim
Nam Kyu Lee
Woo Jae Jang
Joon Gyo Oh
Yoon-Jung Lee
Woong Sik Kim
Jin-Heung Sung
Key An Um
Original Assignee
Sk Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39090946&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP088951(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sk Chemicals Co Ltd filed Critical Sk Chemicals Co Ltd
Publication of ECSP088951A publication Critical patent/ECSP088951A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se relaciona con una composición farmacéutica estable para inyección que contiene docetaxel y un método de preparación de la misma. Más particularmente, la presente invención se relaciona con una composición farmacéutica para inyección que contiene docetaxel que tiene mejor estabilidad de almacenamiento que las medicaciones convencionales, que se prepara disolviendo el docetaxel, un compuesto insoluble en agua, en agua destilada después de mezclarlo con la ciclodextrina (CD) y un polímero soluble en agua, tal como metilcelulosa hidroxipropil (HPMC), glicol de polietileno (PEG ) o (PVP) y liofilizando la mezcla, y un método para prepararla.
EC2008008951A 2006-05-22 2008-12-11 /composición farmacéutica estable que contiene docetaxel y método para su fabricación ECSP088951A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20060045715 2006-05-22
KR1020070049340A KR100917809B1 (ko) 2006-05-22 2007-05-21 우수한 저장안정성을 갖는 도세탁셀 함유 주사제 조성물

Publications (1)

Publication Number Publication Date
ECSP088951A true ECSP088951A (es) 2009-02-27

Family

ID=39090946

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2008008951A ECSP088951A (es) 2006-05-22 2008-12-11 /composición farmacéutica estable que contiene docetaxel y método para su fabricación

Country Status (24)

Country Link
US (1) US8791152B2 (es)
EP (1) EP2019664B1 (es)
JP (1) JP5369332B2 (es)
KR (2) KR100917809B1 (es)
CN (1) CN101484137B (es)
AU (1) AU2007252371B2 (es)
BR (1) BRPI0711893A2 (es)
CA (1) CA2653124C (es)
CR (1) CR10485A (es)
EA (1) EA014071B1 (es)
EC (1) ECSP088951A (es)
ES (1) ES2560641T3 (es)
GE (1) GEP20115200B (es)
GT (1) GT200800257A (es)
IL (1) IL195459A (es)
MA (1) MA30501B1 (es)
MX (1) MX2008014948A (es)
MY (1) MY149627A (es)
NO (1) NO20084932L (es)
NZ (1) NZ573202A (es)
SV (1) SV2008003106A (es)
TN (1) TNSN08475A1 (es)
WO (1) WO2007136219A1 (es)
ZA (1) ZA200809998B (es)

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CN102781237A (zh) 2009-11-23 2012-11-14 天蓝制药公司 用于传递治疗剂的基于环糊精的聚合物
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WO2012161520A2 (ko) * 2011-05-23 2012-11-29 에스케이케미칼 주식회사 도세탁셀을 함유하는 액상 주사용 조성물
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MX2016016311A (es) * 2014-06-12 2017-10-12 Univ Notre Dame Du Lac Composición y método para el tratamiento de enfermedades neurológicas y lesión cerebral.
EP3270912B1 (en) * 2015-03-16 2021-08-18 Meridian Lab Pharmaceutical compositions containing taxane-cyclodextrin complexes, method of making and methods of use
ES2898425T3 (es) * 2015-10-20 2022-03-07 Braun Melsungen Ag Composición acuosa que comprende dantroleno
EP3509569A1 (en) * 2016-09-07 2019-07-17 Cadila Healthcare Limited Sterile injectable compositions comprising drug micelles
CN113559277B (zh) * 2018-01-11 2023-11-17 比卡生物科技（广州）有限公司 一种注射用卡巴他赛组合物及其制备方法
US12414914B2 (en) * 2018-07-25 2025-09-16 Bika Biotechnology (Guangzhou) Co., Ltd Docetaxel composition for injection and preparation method therefor
CN111603387A (zh) * 2020-06-03 2020-09-01 芜湖市第二人民医院 一种多西他赛注射液存储装置及其配制方法
CN116355289B (zh) * 2023-03-31 2026-02-03 北京工商大学 一种纳米纤维膜及其原料、制备方法和应用

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Also Published As

Publication number Publication date
KR20070112725A (ko) 2007-11-27
CR10485A (es) 2009-03-02
KR100917809B1 (ko) 2009-09-18
IL195459A (en) 2013-09-30
SV2008003106A (es) 2010-04-30
CN101484137A (zh) 2009-07-15
KR100983376B1 (ko) 2010-09-20
AU2007252371A1 (en) 2007-11-29
CA2653124A1 (en) 2007-11-29
JP2009538294A (ja) 2009-11-05
NO20084932L (no) 2008-12-19
EA014071B1 (ru) 2010-08-30
AU2007252371B2 (en) 2013-07-25
GEP20115200B (en) 2011-04-11
ES2560641T3 (es) 2016-02-22
GT200800257A (es) 2010-10-19
NZ573202A (en) 2010-08-27
HK1128874A1 (zh) 2009-11-13
WO2007136219A1 (en) 2007-11-29
EP2019664A1 (en) 2009-02-04
CN101484137B (zh) 2014-05-14
MA30501B1 (fr) 2009-06-01
KR20090101145A (ko) 2009-09-24
CA2653124C (en) 2014-04-22
JP5369332B2 (ja) 2013-12-18
EP2019664A4 (en) 2013-03-13
EP2019664B1 (en) 2016-01-06
TNSN08475A1 (en) 2010-04-14
US20090163574A1 (en) 2009-06-25
ZA200809998B (en) 2009-11-25
EA200870559A1 (ru) 2009-04-28
IL195459A0 (en) 2009-08-03
MY149627A (en) 2013-09-13
MX2008014948A (es) 2009-02-03
US8791152B2 (en) 2014-07-29
BRPI0711893A2 (pt) 2012-01-10

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