ECSP099200A - Formulación de ibuprofeno con alto indice de disolución y proceso para su preparación - Google Patents

Formulación de ibuprofeno con alto indice de disolución y proceso para su preparación

Info

Publication number
ECSP099200A
ECSP099200A EC2009009200A ECSP099200A ECSP099200A EC SP099200 A ECSP099200 A EC SP099200A EC 2009009200 A EC2009009200 A EC 2009009200A EC SP099200 A ECSP099200 A EC SP099200A EC SP099200 A ECSP099200 A EC SP099200A
Authority
EC
Ecuador
Prior art keywords
ibuprofen
dissolution
formulation
preparation
high index
Prior art date
Application number
EC2009009200A
Other languages
English (en)
Inventor
Peter Gruber
Hubert Keck
Original Assignee
Losan Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Losan Pharma Gmbh filed Critical Losan Pharma Gmbh
Publication of ECSP099200A publication Critical patent/ECSP099200A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Formulaciones efervescentes de ibuprofeno, que contienen (a) un gránulo que contiene un ingrediente activo que contiene una sal de ibuprofeno soluble en agua y un excipiente básico, y (b) un gránulo efervescente que contiene un componente ácido y un componente que forma dióxido de carbono y un proceso para su preparación.
EC2009009200A 2006-09-26 2009-03-20 Formulación de ibuprofeno con alto indice de disolución y proceso para su preparación ECSP099200A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06121278A EP1905428A1 (de) 2006-09-26 2006-09-26 Ibuprofen-Brausezubereitung mit hoher Lösungsgeschwindigkeit und Verfahren zu deren Herstellung

Publications (1)

Publication Number Publication Date
ECSP099200A true ECSP099200A (es) 2009-06-30

Family

ID=37775689

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2009009200A ECSP099200A (es) 2006-09-26 2009-03-20 Formulación de ibuprofeno con alto indice de disolución y proceso para su preparación

Country Status (22)

Country Link
US (1) US20100172981A1 (es)
EP (2) EP1905428A1 (es)
JP (1) JP2010504366A (es)
KR (1) KR20090074784A (es)
CN (1) CN101534797B (es)
AT (1) ATE438387T1 (es)
AU (1) AU2007302161A1 (es)
BR (1) BRPI0717084A2 (es)
CA (1) CA2664420A1 (es)
CO (1) CO6180421A2 (es)
DE (1) DE502007001262D1 (es)
DK (1) DK2061436T3 (es)
EC (1) ECSP099200A (es)
ES (1) ES2331438T3 (es)
IL (1) IL197309A0 (es)
MX (1) MX2009003065A (es)
NZ (1) NZ575183A (es)
PL (1) PL2061436T3 (es)
PT (1) PT2061436E (es)
RU (1) RU2478381C2 (es)
WO (1) WO2008037555A1 (es)
ZA (1) ZA200901478B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2559430E (pt) 2005-03-22 2015-10-09 Stada Arzneimittel Ag Ibuprofeno solubilizado
KR101683293B1 (ko) * 2009-06-29 2016-12-06 라이온 가부시키가이샤 경구용 조성물
JP5663238B2 (ja) * 2009-08-31 2015-02-04 ライオン株式会社 内服固形製剤及びその製造方法
CN102100686A (zh) * 2009-12-21 2011-06-22 北京润德康医药技术有限公司 一种含有布洛芬与精氨酸的药用组合物及其制备方法、用途
CN102743366B (zh) * 2012-07-16 2013-11-20 海南葫芦娃制药有限公司 对乙酰氨基酚泡腾颗粒及其鉴别方法
WO2016042372A1 (en) 2014-09-17 2016-03-24 Steer Engineering Private Limited Effervescent composition and method of making it
WO2017098481A1 (en) 2015-12-12 2017-06-15 Steerlife India Private Limited Effervescent compositions of metformin and processes for preparation thereof
FR3055800B1 (fr) 2016-09-15 2020-06-26 Unither Pharmaceuticals Composition solide a ingestion rapide et deglutition facilitee, sous forme de particules solides non agglomerees, comprenant deux differents types de particules
JP6836375B2 (ja) * 2016-11-21 2021-03-03 花王株式会社 口腔内発泡製剤及びその製造法
GB2595300B (en) * 2020-05-21 2024-03-27 Reckitt Benckiser Health Ltd Novel Formulation
GB2595301B (en) * 2020-05-21 2025-01-08 Reckitt Benckiser Health Ltd Novel Formulation
GB2595453B (en) * 2020-05-21 2024-04-03 Reckitt Benckiser Health Ltd Novel Formulation
US20230292992A1 (en) * 2022-03-18 2023-09-21 CapsoVision, Inc. Apparatus for Thermally Stable Capsule Endoscope Using Effervescent Formulation for Controlling Balloon Inflation Rate
WO2023182904A1 (ru) * 2022-03-21 2023-09-28 Акционерное Общество "Производственная Фармацевтическая Компания Обновление" Шипучий лекарственный препарат для приготовления раствора, способ его изготовления

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1209667B (it) * 1985-11-12 1989-08-30 Zambon Spa Composizione effeverscente adattivita' analgesica.
CH677606A5 (es) * 1988-07-12 1991-06-14 Aesculapius Pharma Sa
DE3838431A1 (de) * 1988-11-12 1990-05-17 Bayer Ag Ibuprofen-brausezubereitungen
CH684929A5 (de) * 1992-11-19 1995-02-15 Sipharm Sisseln Ag Ibuprofen-haltige Brausezusammensetzung und ihre Herstellung.
EP0667149A1 (en) * 1994-02-14 1995-08-16 E-PHARMA TRENTO S.p.A. Ibuprofen based effervescent composition
US5639475A (en) * 1995-02-03 1997-06-17 Eurand America, Incorporated Effervescent microcapsules
DE19606151C2 (de) * 1996-02-20 1999-05-12 Losan Pharma Gmbh Ibuprofen-Brausezubereitung sowie Verfahren zur Herstellung derselben
GB9816899D0 (en) * 1998-08-05 1998-09-30 Boots Co Plc Therapeutic agents
ATE534371T1 (de) * 2003-02-06 2011-12-15 Gebro Pharma Gmbh Pharmazeutische zubereitungen und verfahren zu deren herstellung
WO2006002836A1 (de) * 2004-07-01 2006-01-12 Losan Pharma Gmbh Brausezusammensetzungen von einschlafmitteln
PT2559430E (pt) * 2005-03-22 2015-10-09 Stada Arzneimittel Ag Ibuprofeno solubilizado
EP1886423A1 (en) 2005-05-12 2008-02-13 Perlos Oyj Optical signal processing device

Also Published As

Publication number Publication date
ZA200901478B (en) 2010-03-31
CN101534797A (zh) 2009-09-16
CO6180421A2 (es) 2010-07-19
WO2008037555A1 (de) 2008-04-03
KR20090074784A (ko) 2009-07-07
EP2061436A1 (de) 2009-05-27
PT2061436E (pt) 2009-10-30
MX2009003065A (es) 2009-05-28
RU2478381C2 (ru) 2013-04-10
PL2061436T3 (pl) 2009-12-31
JP2010504366A (ja) 2010-02-12
BRPI0717084A2 (pt) 2013-10-29
IL197309A0 (en) 2009-12-24
CA2664420A1 (en) 2008-04-03
ES2331438T3 (es) 2010-01-04
DK2061436T3 (da) 2009-11-02
EP2061436B1 (de) 2009-08-05
ATE438387T1 (de) 2009-08-15
DE502007001262D1 (de) 2009-09-17
EP1905428A1 (de) 2008-04-02
RU2009107536A (ru) 2010-11-20
US20100172981A1 (en) 2010-07-08
AU2007302161A1 (en) 2008-04-03
CN101534797B (zh) 2012-03-28
NZ575183A (en) 2012-03-30

Similar Documents

Publication Publication Date Title
ECSP099200A (es) Formulación de ibuprofeno con alto indice de disolución y proceso para su preparación
EA200702552A1 (ru) Непрерывный способ получения хлоргидринов
BRPI0512347B8 (pt) preparação da pregabalina e compostos relacionados
DK2264043T3 (da) Heterobifunktionelle pan-selektin-inhibitorer
MX2009013255A (es) Matriz de solidificacion que incluye una sal de un acido mono-, di- o tri-carboxilico saturado de cadena recta.
IL189995A (en) Agrochemical formulations
WO2006081252A3 (en) Use of 1-benzyl-1-hydr0xy-2, 3-diamino-propyl amines, 3-benzyl-3-hydroxy-2-amino-propionic acid amides and related compounds as analgesics
WO2009098191A3 (en) Method to produce hyperpolarised amino acids and aminosulphonic acids
EA200701073A1 (ru) Способ получения севофлурана
AU2008242996A8 (en) Polyquaternium-1 synthesis methods
BRPI0416298A (pt) método para manufatura de poliacroleìna
ATE474556T1 (de) Galenische form zur transmukosalen verabreichung von paracetamol
WO2007120725A3 (en) Pharmaceutical composition containing sympathomimetic amine salt and co-distillable additive
SG149080A1 (en) Composition comprising a nsaid and paracetamol
GEP20105079B (en) Method for producing 3-(2,2,2-trimethylhydrazinium) propionate dihydrate
DK2094116T3 (da) Fast eller vandig alkalisk fremstilling omfattende en kreatinkomponent, fremgangsmåde til fremstilling heraf og anvendelse heraf
WO2007098924A3 (de) Zusammensetzung umfassend ein mittel zum stabilisieren von wirkstoffen im trinkwasser und eine brausemischung, verfahren zu deren herstellung und deren verwendung
DK1765770T3 (da) Fremgangsmåde til fremstilling af gabapentin
FR2956810B1 (fr) Composition cosmetique a base d'acide ellagique ou d'un de ses derives et d'un melange particulier de tensioactifs anioniques et amphoteres ou zwitterioniques.
AR056469A1 (es) Ibuprofeno solubilizado
BRPI0406626A (pt) Método para fazer um arranjo de formulações para tratar descontinuidades mucosais, produto, formulação para tratar descontinuidades mucosais, kit, dispositivo para tratar descontinuidades mucosais, sistema, e, composição esfoliante
DE502004010375D1 (de) Gezielte granulation durch neutralisation im compomix
ATE533536T1 (de) Verfahren zur herstellung niedrigviskoser polymergele
UA96940C2 (ru) Композиция, которая содержит агент для стабилизации активных ингредиентов в питьевой воде и шипучую смесь, способ приготовления такой композиции и ее использование
BRPI0516106A (pt) método para a limpeza de derivados de 3-hidroxiamidinofenilalanina pela precipitação e recristalização de sal e um ácido sulfÈnico aromático