ECSP099392A - Anticuerpos agonistas trkb y usos de estos - Google Patents

Anticuerpos agonistas trkb y usos de estos

Info

Publication number
ECSP099392A
ECSP099392A EC2009009392A ECSP099392A ECSP099392A EC SP099392 A ECSP099392 A EC SP099392A EC 2009009392 A EC2009009392 A EC 2009009392A EC SP099392 A ECSP099392 A EC SP099392A EC SP099392 A ECSP099392 A EC SP099392A
Authority
EC
Ecuador
Prior art keywords
agonist antibodies
trkb agonist
trkb
antibodies
methods
Prior art date
Application number
EC2009009392A
Other languages
English (en)
Inventor
Marc Nasoff
Yan Wang
Steven B Cohen
Original Assignee
Irm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Irm Llc filed Critical Irm Llc
Publication of ECSP099392A publication Critical patent/ECSP099392A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Los anticuerpos agonistas TrkB y los métodos para sus usos son provistos.
EC2009009392A 2006-11-09 2009-06-08 Anticuerpos agonistas trkb y usos de estos ECSP099392A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85816906P 2006-11-09 2006-11-09

Publications (1)

Publication Number Publication Date
ECSP099392A true ECSP099392A (es) 2009-07-31

Family

ID=39365312

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2009009392A ECSP099392A (es) 2006-11-09 2009-06-08 Anticuerpos agonistas trkb y usos de estos

Country Status (27)

Country Link
US (1) US20100150914A1 (es)
EP (1) EP2087007A2 (es)
JP (1) JP2010509354A (es)
KR (1) KR20090088896A (es)
CN (1) CN101573381A (es)
AR (1) AR063640A1 (es)
AU (1) AU2007316418A1 (es)
BR (1) BRPI0719000A2 (es)
CA (1) CA2669205A1 (es)
CL (1) CL2007003236A1 (es)
CO (1) CO6180432A2 (es)
CR (1) CR10779A (es)
DO (1) DOP2009000102A (es)
EA (1) EA200970469A1 (es)
EC (1) ECSP099392A (es)
IL (1) IL198468A0 (es)
MA (1) MA30922B1 (es)
MX (1) MX2009004881A (es)
NI (1) NI200900081U (es)
NO (1) NO20092217L (es)
PE (1) PE20081168A1 (es)
RU (1) RU2009121641A (es)
SM (1) SMAP200900040A (es)
TN (1) TN2009000181A1 (es)
TW (1) TW200829270A (es)
WO (1) WO2008058127A2 (es)
ZA (1) ZA200902943B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201000603A1 (ru) * 2007-10-23 2010-12-30 Новартис Аг ПРИМЕНЕНИЕ АНТИТЕЛ К TrkB ДЛЯ ЛЕЧЕНИЯ РЕСПИРАТОРНЫХ НАРУШЕНИЙ
CN102015769B (zh) 2008-01-17 2014-12-10 Irm责任有限公司 改进的抗-trkb抗体
WO2010106187A2 (en) * 2009-03-20 2010-09-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Inhibitors of cathepsin s for prevention or treatment of obesity-associated disorders
GB2491106A (en) * 2011-05-18 2012-11-28 Univ Basel Antibodies against tropomyosin-related kinase B receptors
EP2788027A2 (en) * 2011-12-09 2014-10-15 Novo Nordisk A/S Glp-1 agonists
CN102901815B (zh) * 2012-11-05 2014-10-22 武汉远征世纪制药有限公司 一种检测TrkB受体816/817位酪氨酸位点活性的ELISA试剂盒及其使用方法
CN102944674B (zh) * 2012-11-05 2014-10-22 武汉远征世纪制药有限公司 一种检测TrkB受体pan-Tyr位点活性的ELISA试剂盒及其使用方法
JP6868394B2 (ja) 2014-05-16 2021-05-12 ファイザー・インク 二重特異性抗体
CN104524568B (zh) * 2015-01-08 2018-04-20 中国人民解放军第二军医大学 一种治疗肥胖症的药物组合物及其应用
BR112018001900A2 (pt) 2015-07-28 2018-09-18 Otonomy, Inc. composições agonistas de trkb ou trkc e métodos para o tratamento de condições óticas
TW201730206A (zh) * 2015-11-17 2017-09-01 葛蘭素史克智慧財產發展有限公司 用於治療神經及其他疾病之結合激動劑
US9914781B1 (en) 2016-11-08 2018-03-13 Glaxosmithkline Intellectual Property Development Limited Binding agonist for treatment of neurological and other disorders
EP3612625A4 (en) 2017-04-21 2021-08-18 Mellitus, LLC PROCEDURE AND ANTIBODIES FOR DIABETES ASSOCIATED APPLICATIONS
US10793634B2 (en) 2017-06-09 2020-10-06 Boehringer Ingelheim International Gmbh Anti-TrkB antibodies
EP3717514A1 (en) 2017-11-30 2020-10-07 Regeneron Pharmaceuticals, Inc. Anti-trkb monoclonal antibodies and methods of use
WO2019165421A1 (en) * 2018-02-26 2019-08-29 Minerva Biotechnologies Corporation Diagnostic methods using anti-muc1* antibodies
CN110818797B (zh) * 2018-08-09 2022-11-04 东莞市朋志生物科技有限公司 一种抗人ca153蛋白的重组抗体
JP7633397B2 (ja) 2020-10-21 2025-02-19 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 眼の疾患の処置のための二重特異性抗ＶＥＧＦ及び抗ＴｒｋＢ結合分子
WO2023125485A1 (en) * 2021-12-28 2023-07-06 4B Technologies (Beijing) Co., Limited TrkB ANTIBODY AND APPLICATION THEREOF

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1541682A3 (en) 1988-09-02 2005-07-06 Dyax Corp. Generation and selection of recombinant varied binding proteins
WO1991010737A1 (en) 1990-01-11 1991-07-25 Molecular Affinities Corporation Production of antibodies using gene libraries
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
ATE414768T1 (de) 1991-04-10 2008-12-15 Scripps Research Inst Bibliotheken heterodimerer rezeptoren mittels phagemiden
ATE463573T1 (de) 1991-12-02 2010-04-15 Medimmune Ltd Herstellung von autoantikörpern auf phagenoberflächen ausgehend von antikörpersegmentbibliotheken
WO1995015982A2 (en) 1993-12-08 1995-06-15 Genzyme Corporation Process for generating specific antibodies
DE69531148T2 (de) 1994-01-31 2004-04-29 Trustees Of Boston University, Boston Bibliotheken aus polyklonalen antikörpern
US5601820A (en) * 1994-07-07 1997-02-11 Children's Hospital Of Philadelphia Compositions and methods of making and using human full length TRK-B
GT200600240A (es) * 2005-06-06 2007-03-14 Anticuerpos monoclonales anti-trkb y usos de los mismos
EP1988923A1 (en) * 2006-02-02 2008-11-12 Rinat Neuroscience Corp. Methods for treating unwanted weight loss or eating disorders by administering a trkb agonist
US7935342B2 (en) * 2006-02-02 2011-05-03 Rinat Neuroscience Corp. Methods for treating obesity by administering a trkB antagonist

Also Published As

Publication number Publication date
BRPI0719000A2 (pt) 2013-12-10
NO20092217L (no) 2009-06-09
NI200900081U (es) 2010-03-16
CA2669205A1 (en) 2008-05-15
AU2007316418A1 (en) 2008-05-15
CN101573381A (zh) 2009-11-04
US20100150914A1 (en) 2010-06-17
MA30922B1 (fr) 2009-11-02
MX2009004881A (es) 2009-05-21
PE20081168A1 (es) 2008-09-22
CO6180432A2 (es) 2010-07-19
CL2007003236A1 (es) 2008-06-13
IL198468A0 (en) 2011-08-01
AR063640A1 (es) 2009-02-04
WO2008058127A3 (en) 2008-10-02
DOP2009000102A (es) 2010-10-31
EA200970469A1 (ru) 2010-04-30
JP2010509354A (ja) 2010-03-25
WO2008058127A2 (en) 2008-05-15
KR20090088896A (ko) 2009-08-20
CR10779A (es) 2009-07-03
TW200829270A (en) 2008-07-16
TN2009000181A1 (en) 2010-10-18
WO2008058127A9 (en) 2008-08-21
EP2087007A2 (en) 2009-08-12
ZA200902943B (en) 2010-05-26
SMAP200900040A (it) 2010-01-19
RU2009121641A (ru) 2010-12-20

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