MA30922B1 - Anticorps d'agonistes de trkb et leurs utilisations - Google Patents

Anticorps d'agonistes de trkb et leurs utilisations

Info

Publication number
MA30922B1
MA30922B1 MA31923A MA31923A MA30922B1 MA 30922 B1 MA30922 B1 MA 30922B1 MA 31923 A MA31923 A MA 31923A MA 31923 A MA31923 A MA 31923A MA 30922 B1 MA30922 B1 MA 30922B1
Authority
MA
Morocco
Prior art keywords
agonist antibodies
trkb agonist
trkb
antibodies
methods
Prior art date
Application number
MA31923A
Other languages
English (en)
Inventor
Yan Wang
Steven B Cohen
Marc Nasoff
Original Assignee
Irm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Irm Llc filed Critical Irm Llc
Publication of MA30922B1 publication Critical patent/MA30922B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'INVENTION CONCERNE DES AGONISTES D'ANTICORPS DE TRKB ET LEURS PROCÉDÉS D'UTILISATION.
MA31923A 2006-11-09 2009-05-27 Anticorps d'agonistes de trkb et leurs utilisations MA30922B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85816906P 2006-11-09 2006-11-09

Publications (1)

Publication Number Publication Date
MA30922B1 true MA30922B1 (fr) 2009-11-02

Family

ID=39365312

Family Applications (1)

Application Number Title Priority Date Filing Date
MA31923A MA30922B1 (fr) 2006-11-09 2009-05-27 Anticorps d'agonistes de trkb et leurs utilisations

Country Status (27)

Country Link
US (1) US20100150914A1 (fr)
EP (1) EP2087007A2 (fr)
JP (1) JP2010509354A (fr)
KR (1) KR20090088896A (fr)
CN (1) CN101573381A (fr)
AR (1) AR063640A1 (fr)
AU (1) AU2007316418A1 (fr)
BR (1) BRPI0719000A2 (fr)
CA (1) CA2669205A1 (fr)
CL (1) CL2007003236A1 (fr)
CO (1) CO6180432A2 (fr)
CR (1) CR10779A (fr)
DO (1) DOP2009000102A (fr)
EA (1) EA200970469A1 (fr)
EC (1) ECSP099392A (fr)
IL (1) IL198468A0 (fr)
MA (1) MA30922B1 (fr)
MX (1) MX2009004881A (fr)
NI (1) NI200900081U (fr)
NO (1) NO20092217L (fr)
PE (1) PE20081168A1 (fr)
RU (1) RU2009121641A (fr)
SM (1) SMAP200900040A (fr)
TN (1) TN2009000181A1 (fr)
TW (1) TW200829270A (fr)
WO (1) WO2008058127A2 (fr)
ZA (1) ZA200902943B (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201000603A1 (ru) * 2007-10-23 2010-12-30 Новартис Аг ПРИМЕНЕНИЕ АНТИТЕЛ К TrkB ДЛЯ ЛЕЧЕНИЯ РЕСПИРАТОРНЫХ НАРУШЕНИЙ
CL2009000090A1 (es) 2008-01-17 2009-07-24 Irm Llc Anticuerpo que se une al receptor de tirosina quinasa b (trkb); composicion que comprende el anticuerpo; metodo para reducir los niveles de glucosa en la sangre y/o el peso corporal en un individuo.
EP2408455B1 (fr) * 2009-03-20 2014-06-04 INSERM (Institut National de la Santé et de la Recherche Médicale) Inhibiteurs de la cathepsine pour la prévention ou le traitement de troubles liés à l'obésité
GB2491106A (en) * 2011-05-18 2012-11-28 Univ Basel Antibodies against tropomyosin-related kinase B receptors
CN104244981A (zh) * 2011-12-09 2014-12-24 诺和诺德A/S Glp-1激动剂
CN102901815B (zh) * 2012-11-05 2014-10-22 武汉远征世纪制药有限公司 一种检测TrkB受体816/817位酪氨酸位点活性的ELISA试剂盒及其使用方法
CN102944674B (zh) * 2012-11-05 2014-10-22 武汉远征世纪制药有限公司 一种检测TrkB受体pan-Tyr位点活性的ELISA试剂盒及其使用方法
US10392438B2 (en) 2014-05-16 2019-08-27 Pfizer Inc. Bispecific antibodies
CN104524568B (zh) * 2015-01-08 2018-04-20 中国人民解放军第二军医大学 一种治疗肥胖症的药物组合物及其应用
WO2017019907A1 (fr) 2015-07-28 2017-02-02 Otonomy, Inc. Compositions d'agoniste trkb ou trkc et méthodes de traitement de troubles otiques
WO2017085035A1 (fr) * 2015-11-17 2017-05-26 Glaxosmithkline Intellectual Property Development Limited Agonistes de liaison utilisés pour le traitement de troubles neurologiques et d'autres troubles
US9914781B1 (en) 2016-11-08 2018-03-13 Glaxosmithkline Intellectual Property Development Limited Binding agonist for treatment of neurological and other disorders
JP7303182B2 (ja) 2017-04-21 2023-07-04 メリタス エルエルシー 糖尿病関連用途のための方法及び抗体
US10793634B2 (en) * 2017-06-09 2020-10-06 Boehringer Ingelheim International Gmbh Anti-TrkB antibodies
AU2018375340C1 (en) * 2017-11-30 2026-05-14 Regeneron Pharmaceuticals, Inc. Anti-TrkB monoclonal antibodies and methods of use
EP3759145A4 (fr) 2018-02-26 2022-03-09 Minerva Biotechnologies Corporation Procédés de diagnostic utilisant des anticorps anti-muc1*
CN110818797B (zh) * 2018-08-09 2022-11-04 东莞市朋志生物科技有限公司 一种抗人ca153蛋白的重组抗体
JP7633397B2 (ja) 2020-10-21 2025-02-19 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 眼の疾患の処置のための二重特異性抗ＶＥＧＦ及び抗ＴｒｋＢ結合分子
WO2023125485A1 (fr) * 2021-12-28 2023-07-06 4B Technologies (Beijing) Co., Limited Anticorps trkb et son application

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0768377A1 (fr) 1988-09-02 1997-04-16 Protein Engineering Corporation Production et sélection de protéines de liaison diversifiées de recombinaison
AU7247191A (en) 1990-01-11 1991-08-05 Molecular Affinities Corporation Production of antibodies using gene libraries
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
AU662148B2 (en) 1991-04-10 1995-08-24 Scripps Research Institute, The Heterodimeric receptor libraries using phagemids
PT1696031E (pt) 1991-12-02 2010-06-25 Medical Res Council Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
JPH09506262A (ja) 1993-12-08 1997-06-24 ジェンザイム・コーポレイション 特異的抗体の製造方法
PT744958E (pt) 1994-01-31 2003-11-28 Univ Boston Bancos de anticorpos policlonais
US5601820A (en) * 1994-07-07 1997-02-11 Children's Hospital Of Philadelphia Compositions and methods of making and using human full length TRK-B
EP2298813A3 (fr) * 2005-06-06 2012-03-21 Wyeth LLC Anticorps monoclonaux anti-TRKB et utilisations de ceux-ci
CA2637707A1 (fr) * 2006-02-02 2007-08-09 Rinat Neuroscience Corporation Procedes de traitement de l'obesite par administration d'un antagoniste trkb
CN101400367A (zh) * 2006-02-02 2009-04-01 瑞纳神经科学公司 施用trkb激动剂治疗不希望的重量减轻或进食障碍的方法

Also Published As

Publication number Publication date
EP2087007A2 (fr) 2009-08-12
NO20092217L (no) 2009-06-09
NI200900081U (es) 2010-03-16
MX2009004881A (es) 2009-05-21
IL198468A0 (en) 2011-08-01
EA200970469A1 (ru) 2010-04-30
TW200829270A (en) 2008-07-16
SMAP200900040A (it) 2010-01-19
KR20090088896A (ko) 2009-08-20
WO2008058127A3 (fr) 2008-10-02
PE20081168A1 (es) 2008-09-22
BRPI0719000A2 (pt) 2013-12-10
WO2008058127A9 (fr) 2008-08-21
JP2010509354A (ja) 2010-03-25
ECSP099392A (es) 2009-07-31
WO2008058127A2 (fr) 2008-05-15
CL2007003236A1 (es) 2008-06-13
CO6180432A2 (es) 2010-07-19
TN2009000181A1 (en) 2010-10-18
AR063640A1 (es) 2009-02-04
AU2007316418A1 (en) 2008-05-15
ZA200902943B (en) 2010-05-26
RU2009121641A (ru) 2010-12-20
US20100150914A1 (en) 2010-06-17
DOP2009000102A (es) 2010-10-31
CN101573381A (zh) 2009-11-04
CA2669205A1 (fr) 2008-05-15
CR10779A (es) 2009-07-03

Similar Documents

Publication Publication Date Title
MA30910B1 (fr) Anticorps et immunoconjugues, et leurs utilisations
MA32535B1 (fr) Compositions et procédés pour des anticorps ciblant une protéine du complément c5
MA30153B1 (fr) Anticorps anti-ox40l et methodes correspondantes
MA30497B1 (fr) Anticorps et immunco-conjugues, et leurs utilisations.
MA30945B1 (fr) Anticorps anti-tat226 et immunoconjugués
MA29528B1 (fr) Agents de fixation
MA31231B1 (fr) Anticorps anti-robo4 et utilisations de ceux-ci
NO20083397L (no) Anti-EphB4-antistoffer og fremgangsmater for anvendelse av disse
MA33256B1 (fr) Anticorps et immunoconjugués anti-fcrh5 et procédés d'utilisation
EP2032159A4 (fr) Combinaison d'anticorps de fc riib et d'anticorps spécifiques de cd20 et leurs procédés d'utilisation
FR15C0048I1 (fr) Anticorps antagonistes de il-17
TN2009000181A1 (en) Agonist trkb antibodies and uses thereof
MA34749B1 (fr) Anticorps anti-récepteur de la barrière hémato-encéphalique à faible affinité et leurs utilisations
MA34818B1 (fr) Anticorps anti-pcsk9 et procédés d'utilisation
MA30684B1 (fr) Anticorps anti-mn et leurs procedes d'utilisation.
EP1915177A4 (fr) Anticorps d'alpha-synucléine et techniques associées
EP1964852A4 (fr) Anticorps anti-ilt7
MA33210B1 (fr) Nouveaux anticorps anti-a5b1 et leurs utilisations
EP2121008A4 (fr) Utilisations de l'anticorps monoclonal 8h9
PA8850201A1 (es) Combinaciones antitumorales que contienen anticuerpos
CL2008002885A1 (es) Anticuerpo anti-receptor de interleucina-6 (il-6); y composicion farmaceutica que lo comprende
PA8849901A1 (es) Combinaciones antitumorales que contienen anticuerpos que reconocen específicamente cd38 y la citarabina
EP2322562A4 (fr) Anticorps monoclonal et immunodosage l'utilisant
MA29154B1 (fr) Promedicament amide de gemcitabine, compositions et utilisations associees
HN2006015949A (es) Anticuerpos de p-caderina