ECSP099506A - DERIVATIVES OF 2-QUINOLINONA AND 2 QUINOXALINONA AND ITS USE AS ANTI BACTERIAL AGENTS - Google Patents

DERIVATIVES OF 2-QUINOLINONA AND 2 QUINOXALINONA AND ITS USE AS ANTI BACTERIAL AGENTS

Info

Publication number
ECSP099506A
ECSP099506A EC2009009506A ECSP099506A ECSP099506A EC SP099506 A ECSP099506 A EC SP099506A EC 2009009506 A EC2009009506 A EC 2009009506A EC SP099506 A ECSP099506 A EC SP099506A EC SP099506 A ECSP099506 A EC SP099506A
Authority
EC
Ecuador
Prior art keywords
quinoxalinona
quinolinona
derivatives
bacterial agents
anti bacterial
Prior art date
Application number
EC2009009506A
Other languages
Spanish (es)
Inventor
Folkert Reck
Janelle Comita-Prevoir
Mark Cronin
Bolin Geng
Andrew Aydon Godfrey
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39046831&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP099506(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ECSP099506A publication Critical patent/ECSP099506A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La presente invención se refiere a compuestos de Fórmula (I): y sales farmacéuticamente aceptables de los mismos, a su uso en el tratamiento de infecciones bacterianas y a sus métodos de preparación.The present invention relates to compounds of Formula (I): and pharmaceutically acceptable salts thereof, their use in the treatment of bacterial infections and their methods of preparation.

EC2009009506A 2006-12-15 2009-07-09 DERIVATIVES OF 2-QUINOLINONA AND 2 QUINOXALINONA AND ITS USE AS ANTI BACTERIAL AGENTS ECSP099506A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87018106P 2006-12-15 2006-12-15
US96916307P 2007-08-30 2007-08-30

Publications (1)

Publication Number Publication Date
ECSP099506A true ECSP099506A (en) 2009-08-28

Family

ID=39046831

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2009009506A ECSP099506A (en) 2006-12-15 2009-07-09 DERIVATIVES OF 2-QUINOLINONA AND 2 QUINOXALINONA AND ITS USE AS ANTI BACTERIAL AGENTS

Country Status (17)

Country Link
EP (1) EP2121702A1 (en)
JP (1) JP2010513255A (en)
KR (1) KR20090090385A (en)
AR (1) AR064369A1 (en)
AU (1) AU2007331247B2 (en)
BR (1) BRPI0720236A2 (en)
CA (1) CA2671485A1 (en)
CL (1) CL2007003641A1 (en)
CO (1) CO6190619A2 (en)
EC (1) ECSP099506A (en)
MX (1) MX2009006325A (en)
NO (1) NO20092655L (en)
PE (1) PE20081511A1 (en)
RU (1) RU2009126731A (en)
TW (1) TW200831517A (en)
UY (1) UY30788A1 (en)
WO (1) WO2008071961A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY150958A (en) 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
WO2006137485A1 (en) 2005-06-24 2006-12-28 Toyama Chemical Co., Ltd. Novel nitrogenated heterocyclic compound and salt thereof
EP1992628A1 (en) 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
MX2011003188A (en) 2008-10-10 2011-04-27 Actelion Pharmaceuticals Ltd Oxazolidinyl antibiotics.
AR076222A1 (en) 2009-04-09 2011-05-26 Actelion Pharmaceuticals Ltd DERIVATIVES 2-HYDROXIETIL-1H-QUINOLIN-ONA AND ITS AZAISOTHERAL ANALOGS WITH ANTIBACTERIAL ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
WO2012045150A1 (en) * 2010-10-04 2012-04-12 British Columbia Cancer Agency Branch Detection of fusobacterium in a gastrointestinal sample to diagnose gastrointestinal cancer
EP3672960A2 (en) * 2017-08-21 2020-07-01 Acadia Pharmaceuticals Inc. Compounds, salts thereof and their use for the treatment of diseases
MX2020001757A (en) 2017-08-21 2020-09-07 Acadia Pharm Inc COMPOUNDS, SALTS THEREOF AND METHODS FOR THE TREATMENT OF DISEASES.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19601265A1 (en) * 1996-01-16 1997-07-17 Bayer Ag 2-oxo and 2-thio-1,2-dihydroquinolinyl oxazolidinones
TW200409637A (en) 2002-06-26 2004-06-16 Glaxo Group Ltd Compounds
WO2006046552A1 (en) * 2004-10-27 2006-05-04 Toyama Chemical Co., Ltd. Novel nitrogenous heterocyclic compounds and salts thereof
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
WO2006137485A1 (en) * 2005-06-24 2006-12-28 Toyama Chemical Co., Ltd. Novel nitrogenated heterocyclic compound and salt thereof
MX2008014908A (en) * 2006-05-26 2009-05-13 Toyama Chemical Co Ltd Novel heterocyclic compound or salt thereof and intermediate thereof.
EP2029612A1 (en) * 2006-06-09 2009-03-04 Glaxo Group Limited Substituted 1-methyl-1h-quinolin-2-ones and 1-methyl-1h-1,5-naphthyridin-2-ones as antibacterials
GB0613208D0 (en) * 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
EP1992628A1 (en) * 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
JP5315239B2 (en) * 2006-07-20 2013-10-16 グラクソ グループ リミテッド N-ethylquinolone and derivatives and analogs of N-ethylazaquinolone

Also Published As

Publication number Publication date
AU2007331247B2 (en) 2011-10-20
BRPI0720236A2 (en) 2013-12-24
CA2671485A1 (en) 2008-06-19
NO20092655L (en) 2009-09-02
MX2009006325A (en) 2009-07-24
JP2010513255A (en) 2010-04-30
KR20090090385A (en) 2009-08-25
RU2009126731A (en) 2011-01-20
AR064369A1 (en) 2009-04-01
TW200831517A (en) 2008-08-01
AU2007331247A1 (en) 2008-06-19
CL2007003641A1 (en) 2008-09-22
WO2008071961A1 (en) 2008-06-19
WO2008071961A8 (en) 2009-10-22
PE20081511A1 (en) 2008-12-12
EP2121702A1 (en) 2009-11-25
CO6190619A2 (en) 2010-08-19
UY30788A1 (en) 2008-07-31

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