ECSP10010664A - HETEROCYCLIC UREA DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS - Google Patents

HETEROCYCLIC UREA DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS

Info

Publication number
ECSP10010664A
ECSP10010664A EC2010010664A ECSP10010664A ECSP10010664A EC SP10010664 A ECSP10010664 A EC SP10010664A EC 2010010664 A EC2010010664 A EC 2010010664A EC SP10010664 A ECSP10010664 A EC SP10010664A EC SP10010664 A ECSP10010664 A EC SP10010664A
Authority
EC
Ecuador
Prior art keywords
treatment
bacterial infections
urea derivatives
heterocyclic urea
heterocyclic
Prior art date
Application number
EC2010010664A
Other languages
Spanish (es)
Inventor
Pamela Hill
Brian Sherer
John Irvin Manchester
Allison Laura Choy
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40823415&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP10010664(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ECSP10010664A publication Critical patent/ECSP10010664A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Se describen compuestos de fórmula (I) y sus sales farmacéuticamente aceptables. También se describen procedimientos para su preparación, composiciones farmacéuticas que los contienen, su uso como medicamentos y su uso en el tratamiento de infecciones bacterianasCompounds of formula (I) and their pharmaceutically acceptable salts are described. Methods for its preparation, pharmaceutical compositions containing them, their use as medicines and their use in the treatment of bacterial infections are also described.

EC2010010664A 2008-06-04 2010-12-07 HETEROCYCLIC UREA DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS ECSP10010664A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5873608P 2008-06-04 2008-06-04

Publications (1)

Publication Number Publication Date
ECSP10010664A true ECSP10010664A (en) 2011-01-31

Family

ID=40823415

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2010010664A ECSP10010664A (en) 2008-06-04 2010-12-07 HETEROCYCLIC UREA DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS

Country Status (23)

Country Link
US (1) US8283361B2 (en)
EP (1) EP2300463A1 (en)
JP (1) JP2011522026A (en)
KR (1) KR20110014710A (en)
CN (1) CN102105469A (en)
AR (1) AR072045A1 (en)
AU (1) AU2009254930A1 (en)
BR (1) BRPI0915471A2 (en)
CA (1) CA2725568A1 (en)
CL (1) CL2009001349A1 (en)
CO (1) CO6382176A2 (en)
CR (1) CR11825A (en)
DO (1) DOP2010000373A (en)
EA (1) EA201001858A1 (en)
EC (1) ECSP10010664A (en)
IL (1) IL209503A0 (en)
MX (1) MX2010013310A (en)
PE (1) PE20100155A1 (en)
SV (1) SV2010003752A (en)
TW (1) TW201000475A (en)
UY (1) UY31864A (en)
WO (1) WO2009147433A1 (en)
ZA (1) ZA201008610B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006088246A1 (en) * 2005-02-18 2006-08-24 Takeda Pharmaceutical Company Limited Agent for controlling function of gpr34 receptor
TW201102065A (en) * 2009-05-29 2011-01-16 Astrazeneca Ab Heterocyclic urea derivatives and methods of use thereof
US20100317624A1 (en) * 2009-06-08 2010-12-16 Astrazeneca Ab Heterocyclic urea derivatives and methods of use thereof
RU2012146246A (en) 2010-03-31 2014-05-10 Актелион Фармасьютиклз Лтд ANTIBACTERIAL DERIVATIVES OF ISOCHINOLIN-3-ILMOCHEIN
AR088729A1 (en) 2011-03-29 2014-07-02 Actelion Pharmaceuticals Ltd DERIVATIVES OF 3-UREIDOISOQUINOLIN-8-ILO AND A PHARMACEUTICAL COMPOSITION
CN105067814A (en) * 2015-07-24 2015-11-18 中国科学院成都生物研究所 Helicase hydrolysis ATP activity determination method
US11857352B2 (en) 2016-09-06 2024-01-02 The Research Foundation For The State University Of New York Positron imaging tomography imaging agent composition and method for bacterial infection
WO2018074880A2 (en) * 2016-10-20 2018-04-26 한국화학연구원 Pharmaceutical composition for preventing or treating pneumonia including quinolin-4-one derivative or pharmaceutically acceptable salt thereof as active ingredient
CA3057431A1 (en) 2017-03-24 2018-09-27 Taisho Pharmaceutical Co., Ltd. 2(1h)-quinolinone derivative
CN111808089B (en) * 2019-04-10 2023-04-11 四川大学华西医院 Preparation method of drug eprogliflozin for treating diabetes or derivative thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993000342A1 (en) 1991-06-21 1993-01-07 Boehringer Mannheim Italia S.P.A. 2-amino-4-aryl-thiazoles with antiasthmatic and anti-inflammatory activities on the respiratory tract
DE60131015T2 (en) 2000-12-15 2008-07-10 Vertex Pharmaceuticals Inc., Cambridge Bacterial gyrase inhibitors and their use
AR042956A1 (en) 2003-01-31 2005-07-13 Vertex Pharma GIRASA INHIBITORS AND USES OF THE SAME
CN101171247A (en) * 2005-03-04 2008-04-30 阿斯利康(瑞典)有限公司 Pyrrole derivatives as DNA gyrase and topoisomerase inhibitors
US8022816B2 (en) 2005-03-21 2011-09-20 Vela Systems, Inc. System and method for field management using radio frequency tags
US7569907B2 (en) 2005-03-28 2009-08-04 Cooper Technologies Company Hybrid chip fuse assembly having wire leads and fabrication method therefor
WO2006109259A1 (en) 2005-04-13 2006-10-19 Koninklijke Philips Electronics N.V. Encoding with watermarking prior to phase modulation
BRPI0620196A2 (en) * 2005-12-23 2013-01-15 Astrazeneca Ab compound, process for preparing the same, pharmaceutical composition, use of a compound, and methods for producing an antibacterial effect in a warm-blooded animal, for inhibition of bacterial dna gyrase and / or topoisomerase in an animal warm blood and for the treatment of a bacterial infection in a warm-blooded animal
DE102006012337B3 (en) 2006-03-17 2007-11-29 Amphenol-Tuchel Electronics Gmbh Electrical connector
RU2469034C2 (en) * 2006-12-04 2012-12-10 Астразенека Аб Chemical compounds
CN201038186Y (en) 2007-03-08 2008-03-19 鹤山丽得电子实业有限公司 A high power LED
TW200940537A (en) 2008-02-26 2009-10-01 Astrazeneca Ab Heterocyclic urea derivatives and methods of use thereof
WO2009110688A2 (en) 2008-03-06 2009-09-11 Jang Gum Sik Solar light power generator
US20100317624A1 (en) * 2009-06-08 2010-12-16 Astrazeneca Ab Heterocyclic urea derivatives and methods of use thereof

Also Published As

Publication number Publication date
MX2010013310A (en) 2011-03-01
EP2300463A1 (en) 2011-03-30
WO2009147433A1 (en) 2009-12-10
EA201001858A1 (en) 2011-08-30
TW201000475A (en) 2010-01-01
US20100190745A1 (en) 2010-07-29
CL2009001349A1 (en) 2010-12-31
CN102105469A (en) 2011-06-22
JP2011522026A (en) 2011-07-28
US8283361B2 (en) 2012-10-09
IL209503A0 (en) 2011-01-31
AR072045A1 (en) 2010-08-04
DOP2010000373A (en) 2011-01-15
AU2009254930A1 (en) 2009-12-10
SV2010003752A (en) 2011-04-14
CR11825A (en) 2011-02-04
UY31864A (en) 2010-01-29
CA2725568A1 (en) 2009-12-10
ZA201008610B (en) 2012-08-29
KR20110014710A (en) 2011-02-11
CO6382176A2 (en) 2012-02-15
BRPI0915471A2 (en) 2017-06-27
PE20100155A1 (en) 2010-03-25

Similar Documents

Publication Publication Date Title
ECSP10010419A (en) UREA HETEROCYCLIC DERIVATIVES AND METHODS OF USE OF THE SAME-211
UY32158A (en) HETEROCICLIC DERIVATIVES AND METHODS OF USE OF THE SAME
UY30759A1 (en) CHEMICAL COMPOUNDS
UY32315A (en) PIPERIDINE COMPOUNDS AND USES OF THE SAME-596
ECSP10010664A (en) HETEROCYCLIC UREA DERIVATIVES FOR THE TREATMENT OF BACTERIAL INFECTIONS
UY32856A (en) UREA HETEROCYCLIC DERIVATIVES AND METHODS OF USE OF THE SAME
UY32203A (en) AMINO PIRIMIDINAS AND ITS USE IN THERAPY
UY31860A (en) PIRIDINES OF TIAZOLO AS INHIBITORS OF THE GIRASA DNA
UY31865A (en) HETEROCYCLIC UREA DERIVATIVES AND METHODS FOR THE USE OF THE SAME
UY31141A1 (en) PIPERIDINE COMPOUNDS AND ITS USES
ECSP109856A (en) DERIVATIVES OF OXADIAZOL AND ITS USE AS POTENTIALS OF METABOTROPIC RECEIVERS OF GLUTAMATE - 842
NI201100130A (en) PIRIMIDIN INDOLE DERIVATIVES FOR THE TREATMENT OF CANCER.
UY32674A (en) UREA HETEROCICLICAL DERIVATIVES AND THEIR EMPLOYMENT METHODS
UY31481A1 (en) NEW PIRIMIDINE DERIVATIVES, PREPARATION PROCESSES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND APPLICATIONS
UY30544A1 (en) PIRROLO-PIPERIDINE COMPOUNDS AND PHARMACEUTICAL SALTS ACCEPTABLE OF THE SAME, MANUFACTURING PROCESSES, COMPOSITIONS AND APPLICATIONS
CL2011000589A1 (en) Compounds derived from pyrrolidin-2-carboxamide, p53-mdm2 interaction inhibitors; pharmaceutical composition that includes them; and its use in the preparation of useful medicines for the treatment of cancer.
NI201200184A (en) MORPHOLINOPYRIMIDINES AND THEIR USE IN THERAPY
UY31069A1 (en) NEW DERIVATIVES OF IMIDAZOQUINOLA, COMPOSITIONS CONTAINING THEM, PREPARATION PROCESS AND APPLICATIONS
UY32694A (en) UREA HETEROCYCLIC DERIVATIVES AND METHODS OF USE OF THE SAME
UY32316A (en) USEFUL PIPERIDINE DERIVATIVES IN THE TREATMENT OF BACTERIAL INFECTIONS
UY31839A (en) COMPOUNDS
ECSP099506A (en) DERIVATIVES OF 2-QUINOLINONA AND 2 QUINOXALINONA AND ITS USE AS ANTI BACTERIAL AGENTS
CU20110108A7 (en) [4- (1-AMINO-ETIL) -CICLOHEXIL] -METIL-AMINAS AS ANTIBACTERIALS
UY31805A (en) AGONISTS M1, PHARMACEUTICAL COMPOSITIONS OF THE SAME, PROCESSES FOR THEIR PREPARATION AND ITS USES FOR THE TREATMENT OF PAIN
CU20100172A7 (en) UREA HETEROCYCLIC DERIVATIVES AND METHODS OF USE OF THE SAME-211